Homo sapiens

8 known processes

ACAT1

acetyl-CoA acetyltransferase 1

(Aliases: ACAT,T2,MAT,THIL)

ACAT1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid catabolic process GO:0046395 71 0.824
acetyl coa metabolic process GO:0006084 8 0.803
oxidation reduction process GO:0055114 396 0.769
cofactor metabolic process GO:0051186 87 0.720
organic acid catabolic process GO:0016054 71 0.719
monocarboxylic acid catabolic process GO:0072329 37 0.710
lipid modification GO:0030258 84 0.669
lipid oxidation GO:0034440 33 0.663
small molecule catabolic process GO:0044282 92 0.654
fatty acid catabolic process GO:0009062 29 0.574
lipid catabolic process GO:0016042 84 0.567
sulfur compound metabolic process GO:0006790 101 0.543
fatty acid metabolic process GO:0006631 115 0.514
coenzyme metabolic process GO:0006732 65 0.464
cellular lipid catabolic process GO:0044242 65 0.453
lipid metabolic process GO:0006629 381 0.435
Yeast
cellular lipid metabolic process GO:0044255 303 0.375
post embryonic development GO:0009791 2 0.304
multicellular organismal aging GO:0010259 3 0.291
determination of adult lifespan GO:0008340 2 0.200
monocarboxylic acid metabolic process GO:0032787 185 0.181
cellular amino acid metabolic process GO:0006520 116 0.111
fatty acid oxidation GO:0019395 31 0.106
mitochondrial membrane organization GO:0007006 40 0.098
thioester metabolic process GO:0035383 23 0.094
regulation of mitochondrion organization GO:0010821 54 0.088
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.078
apoptotic mitochondrial changes GO:0008637 57 0.078
membrane organization GO:0061024 292 0.073
ribonucleoside triphosphate metabolic process GO:0009199 412 0.072
regulation of cellular ketone metabolic process GO:0010565 50 0.071
negative regulation of transport GO:0051051 176 0.070
regulation of membrane permeability GO:0090559 25 0.068
acyl coa metabolic process GO:0006637 23 0.068
negative regulation of cell death GO:0060548 345 0.066
response to abiotic stimulus GO:0009628 336 0.064
cellular ketone metabolic process GO:0042180 80 0.060
single organism membrane organization GO:0044802 268 0.059
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.058
nucleoside triphosphate metabolic process GO:0009141 422 0.057
amine metabolic process GO:0009308 44 0.054
organic hydroxy compound metabolic process GO:1901615 147 0.054
Yeast
purine nucleoside monophosphate metabolic process GO:0009126 186 0.051
purine ribonucleoside metabolic process GO:0046128 437 0.050
organic acid biosynthetic process GO:0016053 97 0.048
regulation of mitochondrial membrane permeability GO:0046902 25 0.047
regulation of apoptotic signaling pathway GO:2001233 175 0.046
reactive oxygen species metabolic process GO:0072593 75 0.044
fatty acid beta oxidation GO:0006635 22 0.044
energy derivation by oxidation of organic compounds GO:0015980 43 0.044
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.043
mitochondrial transport GO:0006839 60 0.042
regulation of intracellular transport GO:0032386 195 0.040
regulation of cellular amino acid metabolic process GO:0006521 6 0.040
negative regulation of cellular component organization GO:0051129 235 0.040
cellular amine metabolic process GO:0044106 41 0.040
organonitrogen compound biosynthetic process GO:1901566 200 0.039
regulation of cellular amine metabolic process GO:0033238 11 0.039
nucleoside catabolic process GO:0009164 408 0.038
nervous system development GO:0007399 293 0.038
Rat
negative regulation of apoptotic signaling pathway GO:2001234 97 0.037
response to hypoxia GO:0001666 96 0.037
glycosyl compound catabolic process GO:1901658 413 0.037
negative regulation of programmed cell death GO:0043069 321 0.036
alcohol metabolic process GO:0006066 114 0.036
Yeast
small molecule biosynthetic process GO:0044283 157 0.036
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 412 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
purine nucleoside triphosphate catabolic process GO:0009146 392 0.035
female gamete generation GO:0007292 2 0.033
negative regulation of organelle organization GO:0010639 126 0.033
cellular macromolecular complex assembly GO:0034622 324 0.033
ribonucleoside catabolic process GO:0042454 406 0.033
organophosphate catabolic process GO:0046434 430 0.032
ribonucleoside monophosphate metabolic process GO:0009161 187 0.031
alpha amino acid metabolic process GO:1901605 72 0.031
response to decreased oxygen levels GO:0036293 96 0.031
carboxylic acid biosynthetic process GO:0046394 97 0.031
cellular response to decreased oxygen levels GO:0036294 51 0.030
ribonucleotide catabolic process GO:0009261 405 0.030
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.030
cofactor biosynthetic process GO:0051188 31 0.029
cellular response to hypoxia GO:0071456 51 0.029
negative regulation of protein metabolic process GO:0051248 391 0.028
nucleoside monophosphate metabolic process GO:0009123 191 0.028
ribonucleoside triphosphate catabolic process GO:0009203 391 0.028
response to oxygen containing compound GO:1901700 369 0.028
response to external biotic stimulus GO:0043207 261 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.027
atp metabolic process GO:0046034 176 0.027
cellular response to oxygen levels GO:0071453 55 0.026
purine containing compound catabolic process GO:0072523 411 0.025
oogenesis GO:0048477 2 0.025
immune response GO:0006955 307 0.025
cation transport GO:0006812 331 0.025
nucleoside triphosphate catabolic process GO:0009143 394 0.025
regulation of membrane potential GO:0042391 95 0.025
generation of precursor metabolites and energy GO:0006091 68 0.025
nucleotide catabolic process GO:0009166 408 0.024
transmembrane transport GO:0055085 399 0.024
purine nucleoside catabolic process GO:0006152 398 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
ras protein signal transduction GO:0007265 73 0.023
protein processing GO:0016485 226 0.023
dicarboxylic acid metabolic process GO:0043648 29 0.023
response to hormone GO:0009725 175 0.023
Rat
diterpenoid metabolic process GO:0016101 20 0.023
purine nucleotide catabolic process GO:0006195 405 0.022
locomotory behavior GO:0007626 1 0.022
neuromuscular junction development GO:0007528 3 0.022
carbohydrate metabolic process GO:0005975 207 0.022
protein homooligomerization GO:0051260 100 0.021
Rat
purine ribonucleotide catabolic process GO:0009154 404 0.021
succinate metabolic process GO:0006105 1 0.021
vesicle mediated transport GO:0016192 371 0.021
mating GO:0007618 1 0.021
negative regulation of intracellular transport GO:0032387 60 0.020
nerve development GO:0021675 4 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
lipid localization GO:0010876 106 0.020
Worm
maintenance of location GO:0051235 112 0.020
Worm
nucleoside phosphate catabolic process GO:1901292 412 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
sulfur compound biosynthetic process GO:0044272 38 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
chemical homeostasis GO:0048878 306 0.019
spermatid differentiation GO:0048515 4 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
memory GO:0007613 3 0.018
ion transmembrane transport GO:0034220 338 0.018
tripartite regional subdivision GO:0007351 2 0.018
blastoderm segmentation GO:0007350 2 0.018
regeneration GO:0031099 4 0.018
protein tetramerization GO:0051262 47 0.018
single organism cellular localization GO:1902580 332 0.018
segmentation GO:0035282 4 0.018
protein localization to organelle GO:0033365 280 0.018
response to organic cyclic compound GO:0014070 204 0.018
Rat
response to nitrogen compound GO:1901698 184 0.018
cranial nerve development GO:0021545 4 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
positive regulation of transport GO:0051050 336 0.017
rna interference GO:0016246 4 0.017
oocyte differentiation GO:0009994 2 0.017
tricarboxylic acid cycle GO:0006099 4 0.017
regulation of transferase activity GO:0051338 355 0.017
negative regulation of mitochondrion organization GO:0010823 22 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
nitrogen compound transport GO:0071705 191 0.017
rho protein signal transduction GO:0007266 26 0.017
mitochondrial outer membrane permeabilization GO:0097345 15 0.016
reactive oxygen species biosynthetic process GO:1903409 4 0.016
inorganic ion transmembrane transport GO:0098660 231 0.016
monocarboxylic acid biosynthetic process GO:0072330 67 0.016
response to metal ion GO:0010038 84 0.016
innate immune response GO:0045087 178 0.016
regulation of secretion GO:0051046 194 0.016
protein maturation GO:0051604 233 0.016
monovalent inorganic cation transport GO:0015672 128 0.016
citrate metabolic process GO:0006101 2 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 16 0.016
aging GO:0007568 66 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
mitochondrion organization GO:0007005 156 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.015
regulation of protein localization GO:0032880 296 0.015
secretion GO:0046903 254 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
defense response GO:0006952 315 0.015
cellular ion homeostasis GO:0006873 168 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
long chain fatty acid metabolic process GO:0001676 30 0.015
regulation of hormone levels GO:0010817 125 0.015
regulation of protein maturation GO:1903317 150 0.015
purine nucleoside monophosphate catabolic process GO:0009128 158 0.015
fatty acid beta oxidation using acyl coa dehydrogenase GO:0033539 3 0.015
hindbrain development GO:0030902 3 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
lipid biosynthetic process GO:0008610 177 0.015
Yeast
anterior posterior axis specification GO:0009948 2 0.015
protein oligomerization GO:0051259 173 0.015
Rat
small gtpase mediated signal transduction GO:0007264 78 0.015
peripheral nervous system development GO:0007422 2 0.015
regulation of kinase activity GO:0043549 314 0.014
cellular protein complex assembly GO:0043623 188 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
ion homeostasis GO:0050801 230 0.014
cellular modified amino acid metabolic process GO:0006575 64 0.014
biological adhesion GO:0022610 331 0.014
cellular homeostasis GO:0019725 196 0.014
response to organonitrogen compound GO:0010243 156 0.014
regulation of secretion by cell GO:1903530 177 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
negative regulation of protein maturation GO:1903318 142 0.014
cardiac muscle cell contraction GO:0086003 4 0.014
actin mediated cell contraction GO:0070252 12 0.014
metal ion transport GO:0030001 272 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
cell morphogenesis GO:0000902 296 0.014
purine nucleotide biosynthetic process GO:0006164 84 0.014
cell projection organization GO:0030030 252 0.014
cellular respiration GO:0045333 21 0.013
adult locomotory behavior GO:0008344 1 0.013
tricarboxylic acid metabolic process GO:0072350 4 0.013
cytoplasmic transport GO:0016482 379 0.013
oocyte development GO:0048599 1 0.013
metal ion homeostasis GO:0055065 169 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
cellular component morphogenesis GO:0032989 314 0.013
circulatory system development GO:0072359 262 0.013
regulation of cellular response to stress GO:0080135 244 0.013
regulation of protein kinase activity GO:0045859 289 0.013
mitotic cell cycle GO:0000278 326 0.013
Fly
reactive nitrogen species metabolic process GO:2001057 3 0.013
spermatid development GO:0007286 4 0.013
regulation of cellular component movement GO:0051270 334 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
endocytosis GO:0006897 159 0.013
response to activity GO:0014823 0 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
morphogenesis of embryonic epithelium GO:0016331 4 0.013
positive regulation of catabolic process GO:0009896 310 0.013
purine containing compound biosynthetic process GO:0072522 88 0.013
cardiovascular system development GO:0072358 262 0.013
dephosphorylation GO:0016311 209 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
cellular chemical homeostasis GO:0055082 180 0.013
negative regulation of proteolysis GO:0045861 132 0.012
response to other organism GO:0051707 261 0.012
response to biotic stimulus GO:0009607 276 0.012
regulation of protein processing GO:0070613 150 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
cation transmembrane transport GO:0098655 238 0.012
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901029 4 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
cell adhesion GO:0007155 325 0.012
response to bacterium GO:0009617 144 0.012
negative regulation of protein modification process GO:0031400 200 0.012
translation GO:0006412 132 0.012
regulation of cell adhesion GO:0030155 166 0.012
fatty alcohol metabolic process GO:1903173 2 0.012
positive regulation of cell death GO:0010942 263 0.012
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 16 0.012
intracellular protein transport GO:0006886 270 0.012
cation homeostasis GO:0055080 189 0.012
system process GO:0003008 349 0.012
cellular amino acid biosynthetic process GO:0008652 30 0.012
cellular cation homeostasis GO:0030003 163 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
isoprenoid metabolic process GO:0006720 39 0.012
negative regulation of transferase activity GO:0051348 124 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
actin filament based process GO:0030029 224 0.012
organic hydroxy compound transport GO:0015850 63 0.012
negative regulation of cell proliferation GO:0008285 228 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
tissue regeneration GO:0042246 3 0.011
protein targeting GO:0006605 187 0.011
gtp metabolic process GO:0046039 239 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
sleep GO:0030431 2 0.011
neurotransmitter secretion GO:0007269 4 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
glial cell migration GO:0008347 4 0.011
apoptotic signaling pathway GO:0097190 268 0.011
defense response to other organism GO:0098542 129 0.011
protein catabolic process GO:0030163 325 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
response to inorganic substance GO:0010035 127 0.011
cellular macromolecule catabolic process GO:0044265 380 0.011
atp catabolic process GO:0006200 157 0.011
multicellular organismal response to stress GO:0033555 1 0.011
regulation of response to external stimulus GO:0032101 222 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
rhythmic behavior GO:0007622 2 0.011
epithelium development GO:0060429 227 0.011
Rat
negative regulation of apoptotic process GO:0043066 316 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
head development GO:0060322 108 0.011
Rat
endomembrane system organization GO:0010256 196 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
anion transport GO:0006820 161 0.011
negative regulation of developmental process GO:0051093 247 0.011
regulation of peptidase activity GO:0052547 180 0.011
atp synthesis coupled electron transport GO:0042773 4 0.011
regulation of cell differentiation GO:0045595 393 0.011
mitochondrial respiratory chain complex assembly GO:0033108 23 0.011
gtp catabolic process GO:0006184 237 0.011
regulation of cell motility GO:2000145 299 0.011
regulation of cell cycle GO:0051726 393 0.010
negative regulation of endopeptidase activity GO:0010951 84 0.010
protein localization to membrane GO:0072657 160 0.010
secretion by cell GO:0032940 226 0.010
defense response to bacterium GO:0042742 63 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010
pyruvate metabolic process GO:0006090 26 0.010
regulation of cell migration GO:0030334 289 0.010
embryo development GO:0009790 123 0.010
sequestering of metal ion GO:0051238 24 0.010
aerobic respiration GO:0009060 7 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
positive regulation of organelle organization GO:0010638 195 0.010
negative regulation of cell cycle GO:0045786 193 0.010
ossification GO:0001503 121 0.010
interspecies interaction between organisms GO:0044419 156 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
coenzyme biosynthetic process GO:0009108 24 0.010
negative regulation of protein processing GO:0010955 142 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
regulation of synaptic plasticity GO:0048167 3 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
signal transduction by phosphorylation GO:0023014 297 0.010

ACAT1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.153
inherited metabolic disorder DOID:655 242 0.125
amino acid metabolic disorder DOID:9252 50 0.060
cancer DOID:162 167 0.057
disease of cellular proliferation DOID:14566 174 0.057
organ system cancer DOID:0050686 164 0.048
musculoskeletal system disease DOID:17 223 0.043
cardiovascular system disease DOID:1287 106 0.038
central nervous system disease DOID:331 186 0.035
nervous system disease DOID:863 431 0.035
neurodegenerative disease DOID:1289 102 0.034
myopathy DOID:423 104 0.033
muscular disease DOID:0080000 114 0.033
muscle tissue disease DOID:66 113 0.033
endocrine gland cancer DOID:170 26 0.021
sensory system disease DOID:0050155 203 0.020
carbohydrate metabolic disorder DOID:2978 55 0.018
heart disease DOID:114 68 0.016
eye and adnexa disease DOID:1492 150 0.015
gastrointestinal system cancer DOID:3119 52 0.014
organic acidemia DOID:0060159 14 0.014
eye disease DOID:5614 149 0.014
brain disease DOID:936 73 0.013
hyperinsulinemic hypoglycemia DOID:13317 7 0.012
cardiomyopathy DOID:0050700 50 0.011
intrinsic cardiomyopathy DOID:0060036 50 0.011
immune system disease DOID:2914 155 0.011