Homo sapiens

0 known processes

GAK

cyclin G associated kinase

(Aliases: FLJ40395,FLJ16629,MGC99654)

GAK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotory behavior GO:0007626 1 0.382
ribonucleotide catabolic process GO:0009261 405 0.247
protein modification by small protein conjugation GO:0032446 342 0.209
vesicle mediated transport GO:0016192 371 0.198
Mouse
nucleotide catabolic process GO:0009166 408 0.177
single organism membrane organization GO:0044802 268 0.166
small gtpase mediated signal transduction GO:0007264 78 0.158
purine ribonucleoside metabolic process GO:0046128 437 0.158
ribonucleoside triphosphate metabolic process GO:0009199 412 0.155
membrane organization GO:0061024 292 0.154
positive regulation of catabolic process GO:0009896 310 0.149
purine nucleoside catabolic process GO:0006152 398 0.146
regulation of small gtpase mediated signal transduction GO:0051056 156 0.140
actin filament organization GO:0007015 128 0.130
regulation of ras protein signal transduction GO:0046578 155 0.123
ras protein signal transduction GO:0007265 73 0.121
guanosine containing compound metabolic process GO:1901068 244 0.119
rho protein signal transduction GO:0007266 26 0.114
covalent chromatin modification GO:0016569 254 0.112
endomembrane system organization GO:0010256 196 0.112
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.111
actin cytoskeleton organization GO:0030036 207 0.108
gtp metabolic process GO:0046039 239 0.106
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.105
cellular amine metabolic process GO:0044106 41 0.104
guanosine containing compound catabolic process GO:1901069 239 0.103
regulation of purine nucleotide catabolic process GO:0033121 205 0.097
ribonucleoside catabolic process GO:0042454 406 0.096
regulation of cellular amine metabolic process GO:0033238 11 0.093
cytoplasmic transport GO:0016482 379 0.093
glycosyl compound catabolic process GO:1901658 413 0.093
ribonucleoside triphosphate catabolic process GO:0009203 391 0.090
forebrain regionalization GO:0021871 3 0.088
purine nucleoside triphosphate catabolic process GO:0009146 392 0.083
cellular macromolecule catabolic process GO:0044265 380 0.082
actin filament based process GO:0030029 224 0.082
positive regulation of cellular catabolic process GO:0031331 284 0.081
cellular amino acid metabolic process GO:0006520 116 0.080
positive regulation of nucleotide metabolic process GO:0045981 230 0.077
secretion by cell GO:0032940 226 0.076
chromatin modification GO:0016568 298 0.075
positive regulation of nucleoside metabolic process GO:0045979 186 0.073
protein localization to membrane GO:0072657 160 0.070
regulation of protein kinase activity GO:0045859 289 0.069
histone modification GO:0016570 251 0.068
regulation of cellular ketone metabolic process GO:0010565 50 0.068
regulation of gtpase activity GO:0043087 180 0.066
microtubule based process GO:0007017 210 0.065
gtp catabolic process GO:0006184 237 0.064
organophosphate catabolic process GO:0046434 430 0.063
positive regulation of gtp catabolic process GO:0033126 166 0.061
purine containing compound catabolic process GO:0072523 411 0.061
protein ubiquitination GO:0016567 314 0.060
forebrain generation of neurons GO:0021872 3 0.060
purine ribonucleotide catabolic process GO:0009154 404 0.059
cellular ketone metabolic process GO:0042180 80 0.059
positive regulation of rab gtpase activity GO:0032851 39 0.058
activation of protein kinase activity GO:0032147 90 0.058
rab protein signal transduction GO:0032482 4 0.057
determination of adult lifespan GO:0008340 2 0.057
post embryonic development GO:0009791 2 0.057
single organism cellular localization GO:1902580 332 0.056
regulation of cell cycle GO:0051726 393 0.056
cellular protein complex assembly GO:0043623 188 0.055
adult locomotory behavior GO:0008344 1 0.054
establishment of protein localization to membrane GO:0090150 121 0.053
intracellular protein transport GO:0006886 270 0.053
sensory perception GO:0007600 103 0.053
cellular macromolecular complex assembly GO:0034622 324 0.052
regulation of response to dna damage stimulus GO:2001020 94 0.052
positive regulation of nucleotide catabolic process GO:0030813 185 0.052
cellular component morphogenesis GO:0032989 314 0.051
cellular lipid metabolic process GO:0044255 303 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.051
amine metabolic process GO:0009308 44 0.051
nucleoside catabolic process GO:0009164 408 0.050
regulation of nucleoside metabolic process GO:0009118 209 0.050
regulation of nucleotide metabolic process GO:0006140 269 0.050
neuromuscular junction development GO:0007528 3 0.050
behavior GO:0007610 112 0.050
female gamete generation GO:0007292 2 0.049
positive regulation of hydrolase activity GO:0051345 331 0.048
regulation of gtp catabolic process GO:0033124 180 0.048
nucleoside triphosphate metabolic process GO:0009141 422 0.046
modification dependent protein catabolic process GO:0019941 209 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.045
lysosomal transport GO:0007041 33 0.045
segmentation GO:0035282 4 0.044
regulation of secretion by cell GO:1903530 177 0.044
nucleoside triphosphate catabolic process GO:0009143 394 0.043
multicellular organismal aging GO:0010259 3 0.043
macroautophagy GO:0016236 39 0.041
purine ribonucleoside catabolic process GO:0046130 398 0.039
alcohol metabolic process GO:0006066 114 0.039
endocytosis GO:0006897 159 0.039
Mouse
apoptotic signaling pathway GO:0097190 268 0.038
regulation of kinase activity GO:0043549 314 0.038
blastoderm segmentation GO:0007350 2 0.038
positive regulation of transferase activity GO:0051347 227 0.037
protein processing GO:0016485 226 0.037
cellular response to dna damage stimulus GO:0006974 379 0.037
neurotransmitter secretion GO:0007269 4 0.037
modification dependent macromolecule catabolic process GO:0043632 212 0.036
regulation of proteolysis GO:0030162 293 0.036
nucleoside phosphate catabolic process GO:1901292 412 0.036
regulation of dna repair GO:0006282 47 0.036
cell morphogenesis GO:0000902 296 0.036
regulation of establishment of protein localization GO:0070201 242 0.036
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
chromosome segregation GO:0007059 114 0.035
purine nucleotide catabolic process GO:0006195 405 0.035
organophosphate biosynthetic process GO:0090407 163 0.035
positive regulation of cellular component organization GO:0051130 376 0.035
regulation of secretion GO:0051046 194 0.034
cellular protein catabolic process GO:0044257 261 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
negative regulation of cell death GO:0060548 345 0.034
system process GO:0003008 349 0.034
protein maturation GO:0051604 233 0.033
protein localization to organelle GO:0033365 280 0.032
positive regulation of transport GO:0051050 336 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.032
positive regulation of gtpase activity GO:0043547 166 0.032
endosome to lysosome transport GO:0008333 21 0.032
protein oligomerization GO:0051259 173 0.032
regulation of nucleotide catabolic process GO:0030811 205 0.031
positive regulation of protein phosphorylation GO:0001934 313 0.031
cell projection organization GO:0030030 252 0.030
dna repair GO:0006281 198 0.030
negative regulation of cellular component organization GO:0051129 235 0.030
protein catabolic process GO:0030163 325 0.030
lipid modification GO:0030258 84 0.030
regulation of vesicle mediated transport GO:0060627 130 0.029
golgi vesicle transport GO:0048193 80 0.029
innate immune response GO:0045087 178 0.029
regulation of protein transport GO:0051223 213 0.029
regulation of rab protein signal transduction GO:0032483 39 0.029
endosomal transport GO:0016197 129 0.028
response to external biotic stimulus GO:0043207 261 0.028
response to virus GO:0009615 126 0.028
regeneration GO:0031099 4 0.027
organic hydroxy compound metabolic process GO:1901615 147 0.027
lipid metabolic process GO:0006629 381 0.027
compound eye development GO:0048749 1 0.027
Fly
vacuolar transport GO:0007034 34 0.027
endoplasmic reticulum organization GO:0007029 20 0.027
Mouse
neurological system process GO:0050877 163 0.027
regulation of body fluid levels GO:0050878 99 0.027
Mouse
chromatin assembly or disassembly GO:0006333 78 0.026
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.026
histone acetylation GO:0016573 93 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.026
regulation of map kinase activity GO:0043405 108 0.026
response to oxygen containing compound GO:1901700 369 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
negative regulation of protein metabolic process GO:0051248 391 0.025
immune response GO:0006955 307 0.025
regulation of transferase activity GO:0051338 355 0.025
secretion GO:0046903 254 0.024
dna conformation change GO:0071103 113 0.024
microtubule cytoskeleton organization GO:0000226 176 0.024
cation homeostasis GO:0055080 189 0.024
regulation of cellular response to stress GO:0080135 244 0.024
signal transduction by phosphorylation GO:0023014 297 0.023
positive regulation of phosphorylation GO:0042327 394 0.023
cellular response to starvation GO:0009267 58 0.023
protein homooligomerization GO:0051260 100 0.023
positive regulation of ras gtpase activity GO:0032320 117 0.023
defense response GO:0006952 315 0.023
g protein coupled receptor signaling pathway GO:0007186 207 0.022
generation of neurons GO:0048699 152 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
negative regulation of protein transport GO:0051224 75 0.022
regulation of chromosome organization GO:0033044 103 0.022
negative regulation of programmed cell death GO:0043069 321 0.022
negative regulation of phosphorylation GO:0042326 174 0.021
regulation of ras gtpase activity GO:0032318 128 0.021
regulation of rab gtpase activity GO:0032313 39 0.021
cellular component disassembly GO:0022411 92 0.021
Mouse
proteasomal protein catabolic process GO:0010498 176 0.021
mitotic cell cycle GO:0000278 326 0.021
regulation of growth GO:0040008 165 0.021
regulation of mitotic cell cycle GO:0007346 189 0.021
nucleosome assembly GO:0006334 50 0.021
protein acetylation GO:0006473 116 0.021
cellular cation homeostasis GO:0030003 163 0.021
negative regulation of protein phosphorylation GO:0001933 140 0.021
dna packaging GO:0006323 77 0.020
negative regulation of transport GO:0051051 176 0.020
oogenesis GO:0048477 2 0.020
regulation of protein localization GO:0032880 296 0.020
maintenance of location GO:0051235 112 0.020
glycerolipid metabolic process GO:0046486 107 0.020
ribonucleoside monophosphate metabolic process GO:0009161 187 0.020
central nervous system development GO:0007417 123 0.020
Mouse
regulation of mapk cascade GO:0043408 262 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
negative regulation of developmental process GO:0051093 247 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
negative regulation of protein modification process GO:0031400 200 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.019
tissue regeneration GO:0042246 3 0.019
response to organonitrogen compound GO:0010243 156 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
protein localization to plasma membrane GO:0072659 93 0.019
protein polyubiquitination GO:0000209 110 0.019
negative regulation of organelle organization GO:0010639 126 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.018
mapk cascade GO:0000165 288 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
regulation of protein processing GO:0070613 150 0.018
chromatin organization GO:0006325 351 0.018
internal protein amino acid acetylation GO:0006475 101 0.018
cell cell signaling GO:0007267 155 0.018
regulation of cell cycle process GO:0010564 266 0.018
positive regulation of transcription during mitosis GO:0045897 2 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
forebrain neuron differentiation GO:0021879 3 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
actin filament bundle organization GO:0061572 54 0.017
steroid metabolic process GO:0008202 94 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
mitotic cell cycle process GO:1903047 286 0.017
protein dna complex subunit organization GO:0071824 80 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
positive regulation of protein kinase activity GO:0045860 190 0.017
regulation of rho protein signal transduction GO:0035023 79 0.017
dephosphorylation GO:0016311 209 0.017
protein autophosphorylation GO:0046777 123 0.017
neuron differentiation GO:0030182 138 0.017
establishment of protein localization to plasma membrane GO:0090002 68 0.016
plasma membrane organization GO:0007009 115 0.016
sensory perception of mechanical stimulus GO:0050954 37 0.016
peptidyl tyrosine phosphorylation GO:0018108 170 0.016
embryonic skeletal joint morphogenesis GO:0060272 2 0.016
endochondral bone morphogenesis GO:0060350 3 0.016
negative regulation of protein processing GO:0010955 142 0.016
neurogenesis GO:0022008 169 0.016
cell division GO:0051301 168 0.016
regulation of dephosphorylation GO:0035303 96 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
actin filament reorganization GO:0090527 1 0.016
spermatid development GO:0007286 4 0.016
Fly
regulation of protein maturation GO:1903317 150 0.016
protein dna complex assembly GO:0065004 64 0.015
positive regulation of cell death GO:0010942 263 0.015
neuron fate commitment GO:0048663 2 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
peptide secretion GO:0002790 51 0.015
lipid biosynthetic process GO:0008610 177 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
anion transport GO:0006820 161 0.015
response to nitrogen compound GO:1901698 184 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
rna processing GO:0006396 255 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.015
positive regulation of innate immune response GO:0045089 79 0.015
positive regulation of kinase activity GO:0033674 204 0.015
peptidyl lysine acetylation GO:0018394 101 0.015
somitogenesis GO:0001756 2 0.014
embryonic eye morphogenesis GO:0048048 2 0.014
transmembrane transport GO:0055085 399 0.014
signal release GO:0023061 70 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.014
cellular response to external stimulus GO:0071496 111 0.014
actin filament based movement GO:0030048 17 0.014
regulation of cell motility GO:2000145 299 0.014
protein targeting GO:0006605 187 0.014
regulation of cell differentiation GO:0045595 393 0.014
carbohydrate metabolic process GO:0005975 207 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
cellular ion homeostasis GO:0006873 168 0.014
response to extracellular stimulus GO:0009991 85 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
macromolecule deacylation GO:0098732 41 0.014
small molecule biosynthetic process GO:0044283 157 0.014
regulation of protein complex assembly GO:0043254 147 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.013
immune system development GO:0002520 195 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.013
regulation of hormone levels GO:0010817 125 0.013
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 4 0.013
regulation of protein ubiquitination GO:0031396 95 0.013
cell growth GO:0016049 160 0.013
organelle fission GO:0048285 149 0.013
nucleoside phosphate biosynthetic process GO:1901293 109 0.013
exocytosis GO:0006887 71 0.013
nervous system development GO:0007399 293 0.013
Mouse
embryo development GO:0009790 123 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
positive regulation of immune system process GO:0002684 283 0.013
cellular response to nutrient levels GO:0031669 69 0.013
actin mediated cell contraction GO:0070252 12 0.013
positive regulation of map kinase activity GO:0043406 80 0.013
response to hormone GO:0009725 175 0.013
ncrna processing GO:0034470 83 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
cell cycle phase transition GO:0044770 173 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
regulation of exocytosis GO:0017157 46 0.013
negative regulation of protein maturation GO:1903318 142 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
response to fungus GO:0009620 4 0.013
cardiovascular system development GO:0072358 262 0.013
head development GO:0060322 108 0.013
Mouse
rhythmic behavior GO:0007622 2 0.013
organelle localization GO:0051640 84 0.013
spermatid differentiation GO:0048515 4 0.012
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
positive regulation of protein ubiquitination GO:0031398 53 0.012
atp metabolic process GO:0046034 176 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
regulation of defense response GO:0031347 154 0.012
actin filament bundle assembly GO:0051017 54 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
negative regulation of growth GO:0045926 97 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
toxin transport GO:1901998 4 0.012
cellular homeostasis GO:0019725 196 0.012
response to starvation GO:0042594 59 0.012
autophagy GO:0006914 88 0.012
protein acylation GO:0043543 138 0.012
regulation of leukocyte activation GO:0002694 115 0.012
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
response to biotic stimulus GO:0009607 276 0.012
cardiac muscle adaptation GO:0014887 4 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.012
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.012
response to nutrient levels GO:0031667 81 0.012
histone h4 acetylation GO:0043967 47 0.012
synaptic vesicle endocytosis GO:0048488 2 0.012
regulation of synaptic plasticity GO:0048167 3 0.011
anterior posterior axis specification GO:0009948 2 0.011
cell development GO:0048468 328 0.011
Mouse Fly
organ morphogenesis GO:0009887 147 0.011
Mouse Fly
ion homeostasis GO:0050801 230 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
pancreatic juice secretion GO:0030157 4 0.011
response to other organism GO:0051707 261 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
regulation of protein secretion GO:0050708 86 0.011
regulation of cell projection organization GO:0031344 107 0.011
regulation of response to external stimulus GO:0032101 222 0.011
regulation of cellular component movement GO:0051270 334 0.011
taxis GO:0042330 157 0.011
protein secretion GO:0009306 98 0.011
organelle assembly GO:0070925 176 0.011
cell cycle g1 s phase transition GO:0044843 80 0.011
neural plate regionalization GO:0060897 1 0.011
regulation of cell migration GO:0030334 289 0.011
chloride transport GO:0006821 41 0.011
regulation of locomotion GO:0040012 329 0.011
positive regulation of proteolysis GO:0045862 142 0.011
regulation of intracellular transport GO:0032386 195 0.011
mitotic nuclear division GO:0007067 119 0.011
oocyte differentiation GO:0009994 2 0.011
growth GO:0040007 202 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
protein deacylation GO:0035601 39 0.011
positive regulation of rho gtpase activity GO:0032321 56 0.011
hindbrain development GO:0030902 3 0.011
neuroblast proliferation GO:0007405 4 0.011
regulation of peptidase activity GO:0052547 180 0.011
receptor mediated endocytosis GO:0006898 84 0.010
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010
regulation of cytokine production GO:0001817 232 0.010
epithelium development GO:0060429 227 0.010
Mouse
ribose phosphate biosynthetic process GO:0046390 82 0.010
chemical homeostasis GO:0048878 306 0.010
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 97 0.010
cell projection assembly GO:0030031 126 0.010
immune response activating signal transduction GO:0002757 90 0.010
defense response to other organism GO:0098542 129 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.010
ribonucleotide biosynthetic process GO:0009260 81 0.010
nucleosome organization GO:0034728 66 0.010
double strand break repair GO:0006302 101 0.010
oocyte development GO:0048599 1 0.010
response to abiotic stimulus GO:0009628 336 0.010
defense response to virus GO:0051607 71 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
regulation of nervous system development GO:0051960 88 0.010
reproductive process GO:0022414 106 0.010
Fly
positive regulation of mapk cascade GO:0043410 190 0.010

GAK disease predictions

Disease DO term ID Size Probability Func Analog Org
synucleinopathy DOID:0050890 22 0.172
Human
central nervous system disease DOID:331 186 0.172
Human
neurodegenerative disease DOID:1289 102 0.172
Human
nervous system disease DOID:863 431 0.172
Human
parkinson s disease DOID:14330 18 0.059
Human
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
organ system cancer DOID:0050686 164 0.022
musculoskeletal system disease DOID:17 223 0.021
connective tissue disease DOID:65 109 0.015
bone remodeling disease DOID:0080005 26 0.013
bone disease DOID:0080001 88 0.013
osteopetrosis DOID:13533 9 0.013
osteosclerosis DOID:4254 16 0.013