Homo sapiens

46 known processes

NUMB

numb homolog (Drosophila)

(Aliases: S171)

NUMB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cd4 positive alpha beta t cell cytokine production GO:0035743 4 1.000
synaptic vesicle endocytosis GO:0048488 2 0.993
synaptic vesicle transport GO:0048489 5 0.987
phospholipid catabolic process GO:0009395 12 0.987
interleukin 13 secretion GO:0072611 2 0.981
regulation of interleukin 5 secretion GO:2000662 2 0.976
polysaccharide metabolic process GO:0005976 33 0.913
synaptic vesicle recycling GO:0036465 3 0.877
synaptic vesicle localization GO:0097479 5 0.847
carbohydrate metabolic process GO:0005975 207 0.812
positive regulation of interleukin 5 production GO:0032754 3 0.803
regulation of polysaccharide biosynthetic process GO:0032885 20 0.740
organonitrogen compound biosynthetic process GO:1901566 200 0.736
regulation of glucosylceramide catabolic process GO:2000752 1 0.727
phospholipid transport GO:0015914 23 0.708
Worm
single organism carbohydrate metabolic process GO:0044723 193 0.708
regulation of polysaccharide metabolic process GO:0032881 21 0.701
positive regulation of fatty acid beta oxidation GO:0032000 5 0.652
regulation of vesicle mediated transport GO:0060627 130 0.637
Human Fly
regulation of interleukin 13 secretion GO:2000665 2 0.632
establishment of vesicle localization GO:0051650 23 0.625
vesicle mediated transport GO:0016192 371 0.615
Human Worm Fly
positive regulation of cellular component organization GO:0051130 376 0.595
Human Fly
regulation of carbohydrate metabolic process GO:0006109 54 0.587
carbohydrate derivative biosynthetic process GO:1901137 207 0.577
mucopolysaccharide metabolic process GO:1903510 27 0.560
carbohydrate biosynthetic process GO:0016051 42 0.560
synaptic transmission GO:0007268 61 0.525
post embryonic development GO:0009791 2 0.499
interleukin 5 secretion GO:0072603 2 0.487
negative regulation of t cell apoptotic process GO:0070233 4 0.477
hyaluronan metabolic process GO:0030212 15 0.474
membrane hyperpolarization GO:0060081 1 0.470
establishment of organelle localization GO:0051656 59 0.467
vesicle organization GO:0016050 62 0.455
neurogenesis GO:0022008 169 0.451
Mouse Fly
positive regulation of sphingolipid biosynthetic process GO:0090154 1 0.446
secretion GO:0046903 254 0.441
polysaccharide biosynthetic process GO:0000271 27 0.419
aminoglycan metabolic process GO:0006022 39 0.395
long term synaptic potentiation GO:0060291 1 0.361
vesicle localization GO:0051648 26 0.357
endomembrane system organization GO:0010256 196 0.355
negative regulation of hyaluronan biosynthetic process GO:1900126 3 0.318
positive regulation of glucosylceramide catabolic process GO:2000753 1 0.312
glucosylceramide catabolic process GO:0006680 2 0.300
membrane lipid biosynthetic process GO:0046467 27 0.299
memory GO:0007613 3 0.289
positive regulation of transport GO:0051050 336 0.281
Human Fly
aminoglycan biosynthetic process GO:0006023 29 0.272
negative regulation of cellular protein metabolic process GO:0032269 353 0.249
regulation of cellular ketone metabolic process GO:0010565 50 0.249
protein processing GO:0016485 226 0.246
negative regulation of protein metabolic process GO:0051248 391 0.239
ras protein signal transduction GO:0007265 73 0.238
purine containing compound catabolic process GO:0072523 411 0.238
negative regulation of fatty acid beta oxidation GO:0031999 1 0.225
positive regulation of interleukin 13 secretion GO:2000667 1 0.222
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.217
secretion by cell GO:0032940 226 0.215
sphingomyelin catabolic process GO:0006685 2 0.212
establishment of synaptic vesicle localization GO:0097480 5 0.212
regulation of sphingomyelin catabolic process GO:2000754 1 0.208
cellular biogenic amine metabolic process GO:0006576 34 0.206
multicellular organismal aging GO:0010259 3 0.202
regulation of peptidase activity GO:0052547 180 0.201
protein secretion GO:0009306 98 0.199
regulation of ceramide biosynthetic process GO:2000303 2 0.197
protein modification by small protein conjugation GO:0032446 342 0.196
determination of adult lifespan GO:0008340 2 0.195
cellular component morphogenesis GO:0032989 314 0.191
Mouse
regulation of carbohydrate biosynthetic process GO:0043255 27 0.191
regulation of synaptic plasticity GO:0048167 3 0.180
nervous system development GO:0007399 293 0.179
Mouse Fly
endocytosis GO:0006897 159 0.176
Human Fly
phototransduction visible light GO:0007603 2 0.167
positive regulation of interleukin 5 secretion GO:2000664 1 0.167
rhodopsin mediated signaling pathway GO:0016056 1 0.164
regulation of anion transport GO:0044070 25 0.159
positive regulation of immune system process GO:0002684 283 0.155
positive regulation of nucleotide catabolic process GO:0030813 185 0.153
positive regulation of sphingomyelin catabolic process GO:2000755 1 0.150
protein maturation GO:0051604 233 0.144
regulation of ion transport GO:0043269 189 0.144
activation induced cell death of t cells GO:0006924 2 0.144
organophosphate catabolic process GO:0046434 430 0.144
positive regulation of superoxide anion generation GO:0032930 4 0.143
cellular amino acid metabolic process GO:0006520 116 0.143
negative regulation of cell death GO:0060548 345 0.142
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.142
regulation of nucleoside metabolic process GO:0009118 209 0.142
establishment of neuroblast polarity GO:0045200 1 0.137
cell morphogenesis GO:0000902 296 0.135
Mouse
positive regulation of gliogenesis GO:0014015 4 0.135
protein localization to plasma membrane GO:0072659 93 0.134
glycosaminoglycan biosynthetic process GO:0006024 27 0.132
receptor mediated endocytosis GO:0006898 84 0.131
Human
cell cell signaling GO:0007267 155 0.128
negative regulation of catalytic activity GO:0043086 335 0.128
glycosaminoglycan metabolic process GO:0030203 35 0.127
ceramide biosynthetic process GO:0046513 11 0.127
response to light stimulus GO:0009416 87 0.125
collateral sprouting GO:0048668 2 0.122
amine metabolic process GO:0009308 44 0.121
regulation of cellular amino acid metabolic process GO:0006521 6 0.121
regulation of fatty acid transport GO:2000191 8 0.121
positive regulation of mapk cascade GO:0043410 190 0.120
positive regulation of secretion by cell GO:1903532 108 0.117
regulation of hyaluronan biosynthetic process GO:1900125 6 0.117
regulation of proteolysis GO:0030162 293 0.113
regulation of endopeptidase activity GO:0052548 170 0.112
positive regulation of endocytosis GO:0045807 42 0.112
Human Fly
single organism cellular localization GO:1902580 332 0.112
positive regulation of lipid biosynthetic process GO:0046889 22 0.107
negative regulation of peptidase activity GO:0010466 91 0.106
glucosylceramide metabolic process GO:0006678 3 0.103
regulation of kinase activity GO:0043549 314 0.103
cellular macromolecule catabolic process GO:0044265 380 0.101
cardiovascular system development GO:0072358 262 0.100
Fly
regulation of neuron differentiation GO:0045664 70 0.099
regulation of synaptic vesicle endocytosis GO:1900242 1 0.099
rna processing GO:0006396 255 0.098
rab protein signal transduction GO:0032482 4 0.098
cloaca development GO:0035844 1 0.097
peroxisome degradation GO:0030242 1 0.097
leukocyte activation GO:0045321 164 0.097
interleukin 5 production GO:0032634 6 0.096
regulation of protein secretion GO:0050708 86 0.096
regulation of gtpase activity GO:0043087 180 0.096
regulation of t helper cell differentiation GO:0045622 3 0.095
negative regulation of endopeptidase activity GO:0010951 84 0.095
negative regulation of protein processing GO:0010955 142 0.093
neuronal stem cell division GO:0036445 1 0.092
Mouse Fly
long term memory GO:0007616 2 0.091
actin filament based process GO:0030029 224 0.089
cell adhesion GO:0007155 325 0.089
negative regulation of glial cell apoptotic process GO:0034351 6 0.088
protein ubiquitination GO:0016567 314 0.088
negative regulation of transferase activity GO:0051348 124 0.087
regulation of fatty acid oxidation GO:0046320 9 0.086
negative regulation of proteolysis GO:0045861 132 0.086
positive regulation of interleukin 13 production GO:0032736 4 0.086
positive regulation of hydrolase activity GO:0051345 331 0.084
asymmetric neuroblast division GO:0055059 1 0.084
Fly
vesicle coating GO:0006901 9 0.083
epithelial cell migration GO:0010631 119 0.082
negative regulation of apoptotic process GO:0043066 316 0.079
positive regulation of glial cell proliferation GO:0060252 2 0.078
axon regeneration GO:0031103 1 0.077
hemopoiesis GO:0030097 180 0.077
cell projection morphogenesis GO:0048858 129 0.075
Mouse
actin cytoskeleton organization GO:0030036 207 0.075
termination of signal transduction GO:0023021 3 0.074
positive regulation of cell adhesion GO:0045785 84 0.074
organic anion transport GO:0015711 103 0.073
Worm
negative regulation of protein phosphorylation GO:0001933 140 0.073
protein oligomerization GO:0051259 173 0.072
membrane organization GO:0061024 292 0.072
response to radiation GO:0009314 151 0.072
ribonucleoside triphosphate metabolic process GO:0009199 412 0.071
positive regulation of secretion GO:0051047 116 0.071
phototransduction GO:0007602 3 0.070
biological adhesion GO:0022610 331 0.069
cellular macromolecular complex assembly GO:0034622 324 0.069
positive regulation of immune response GO:0050778 159 0.069
regulation of synaptic vesicle transport GO:1902803 3 0.069
gtp metabolic process GO:0046039 239 0.068
t cell activation GO:0042110 99 0.068
purine ribonucleoside metabolic process GO:0046128 437 0.068
cell activation GO:0001775 213 0.068
generation of neurons GO:0048699 152 0.067
Mouse Fly
regulation of glial cell proliferation GO:0060251 4 0.067
regulation of cell migration GO:0030334 289 0.066
negative regulation of fatty acid transport GO:2000192 6 0.066
reactive nitrogen species metabolic process GO:2001057 3 0.065
regulation of transferase activity GO:0051338 355 0.065
neuromuscular junction development GO:0007528 3 0.065
immune response GO:0006955 307 0.065
regulation of endocytosis GO:0030100 72 0.065
Human Fly
monocarboxylic acid catabolic process GO:0072329 37 0.064
gtp catabolic process GO:0006184 237 0.064
fatty acid metabolic process GO:0006631 115 0.064
positive regulation of programmed cell death GO:0043068 249 0.064
positive regulation of ceramide biosynthetic process GO:2000304 1 0.064
positive regulation of cellular amine metabolic process GO:0033240 7 0.064
enzyme linked receptor protein signaling pathway GO:0007167 303 0.063
Worm
ceramide metabolic process GO:0006672 25 0.063
positive regulation of developmental process GO:0051094 314 0.063
Mouse
neuron projection regeneration GO:0031102 1 0.062
regulation of lamellipodium assembly GO:0010591 14 0.062
positive regulation of interleukin 4 production GO:0032753 3 0.062
aging GO:0007568 66 0.062
regulation of postsynaptic membrane potential GO:0060078 1 0.061
regulation of protein kinase activity GO:0045859 289 0.061
regulation of protein serine threonine kinase activity GO:0071900 179 0.061
membrane lipid metabolic process GO:0006643 53 0.061
regulation of mismatch repair GO:0032423 2 0.061
regulation of growth GO:0040008 165 0.060
growth GO:0040007 202 0.060
lamellipodium assembly GO:0030032 26 0.060
mitotic cell cycle GO:0000278 326 0.060
regulation of immune response GO:0050776 201 0.059
negative regulation of protein modification process GO:0031400 200 0.059
organic acid catabolic process GO:0016054 71 0.058
positive regulation of synaptic transmission GO:0050806 4 0.058
negative regulation of phosphorylation GO:0042326 174 0.058
ribonucleoside catabolic process GO:0042454 406 0.058
positive regulation of protein phosphorylation GO:0001934 313 0.058
neuron differentiation GO:0030182 138 0.057
Mouse
guanosine containing compound catabolic process GO:1901069 239 0.057
negative regulation of lymphocyte apoptotic process GO:0070229 8 0.057
regulation of cell morphogenesis GO:0022604 153 0.057
mrna metabolic process GO:0016071 175 0.056
positive regulation of phospholipid scramblase activity GO:1900163 1 0.055
regeneration GO:0031099 4 0.055
apoptotic signaling pathway GO:0097190 268 0.054
lipid transport GO:0006869 90 0.054
Human Worm
regulation of establishment of protein localization GO:0070201 242 0.054
Human
regulation of protein processing GO:0070613 150 0.054
regulation of mapk cascade GO:0043408 262 0.054
regulation of cell growth GO:0001558 135 0.054
regulation of rab protein signal transduction GO:0032483 39 0.054
cell cell junction organization GO:0045216 69 0.054
Mouse
small molecule catabolic process GO:0044282 92 0.054
regulation of synaptic vesicle recycling GO:1903421 1 0.053
regulation of phospholipid catabolic process GO:0060696 3 0.053
nucleoside triphosphate metabolic process GO:0009141 422 0.053
positive regulation of growth GO:0045927 58 0.053
negative regulation of programmed cell death GO:0043069 321 0.053
response to abiotic stimulus GO:0009628 336 0.052
negative regulation of lipid catabolic process GO:0050995 9 0.052
notch signaling pathway GO:0007219 31 0.052
Mouse
lipid localization GO:0010876 106 0.052
Human Worm
cell morphogenesis involved in differentiation GO:0000904 144 0.051
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.051
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.051
oogenesis GO:0048477 2 0.051
reactive oxygen species biosynthetic process GO:1903409 4 0.050
guanosine containing compound metabolic process GO:1901068 244 0.050
positive regulation of protein transport GO:0051222 135 0.050
regulation of ras protein signal transduction GO:0046578 155 0.050
purine nucleoside triphosphate metabolic process GO:0009144 412 0.050
regulation of secretion by cell GO:1903530 177 0.050
cellular protein complex assembly GO:0043623 188 0.050
positive regulation of nucleoside metabolic process GO:0045979 186 0.050
lymphocyte mediated immunity GO:0002449 48 0.049
cellular ketone metabolic process GO:0042180 80 0.049
positive regulation of gtpase activity GO:0043547 166 0.049
negative regulation of plasma membrane long chain fatty acid transport GO:0010748 4 0.049
organic acid transport GO:0015849 65 0.049
negative regulation of hydrolase activity GO:0051346 182 0.048
neurotransmitter secretion GO:0007269 4 0.048
reproductive process GO:0022414 106 0.048
regulation of protein maturation GO:1903317 150 0.048
dephosphorylation GO:0016311 209 0.047
cytoplasmic transport GO:0016482 379 0.047
mrna processing GO:0006397 133 0.047
organelle assembly GO:0070925 176 0.046
positive regulation of phospholipid transport GO:2001140 4 0.046
intermediate filament cytoskeleton organization GO:0045104 17 0.046
regulation of locomotion GO:0040012 329 0.046
t cell homeostasis GO:0043029 3 0.045
immune system development GO:0002520 195 0.045
maintenance of location GO:0051235 112 0.045
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 3 0.045
spinal cord development GO:0021510 4 0.045
positive regulation of ion transport GO:0043270 87 0.045
endothelial cell apoptotic process GO:0072577 26 0.045
lipid metabolic process GO:0006629 381 0.044
negative regulation of protein maturation GO:1903318 142 0.044
positive regulation of interleukin 10 secretion GO:2001181 2 0.044
morphogenesis of embryonic epithelium GO:0016331 4 0.044
lipid modification GO:0030258 84 0.044
anatomical structure formation involved in morphogenesis GO:0048646 284 0.044
positive regulation of phospholipid catabolic process GO:0060697 2 0.043
regulation of lipid biosynthetic process GO:0046890 47 0.043
neuroblast proliferation GO:0007405 4 0.043
Mouse Fly
locomotory behavior GO:0007626 1 0.043
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.042
cellular component assembly involved in morphogenesis GO:0010927 73 0.042
actin filament organization GO:0007015 128 0.042
regulation of endothelial cell migration GO:0010594 67 0.041
organelle fission GO:0048285 149 0.041
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.041
lymphocyte activation GO:0046649 133 0.041
protein stabilization GO:0050821 64 0.041
liposaccharide metabolic process GO:1903509 27 0.041
cellular amine metabolic process GO:0044106 41 0.041
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.041
signal transduction by phosphorylation GO:0023014 297 0.040
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.040
response to oxidative stress GO:0006979 121 0.040
lipid biosynthetic process GO:0008610 177 0.040
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.040
Worm
ameboidal type cell migration GO:0001667 135 0.040
cellular protein catabolic process GO:0044257 261 0.039
covalent chromatin modification GO:0016569 254 0.038
activation of protein kinase activity GO:0032147 90 0.038
sphingolipid metabolic process GO:0006665 38 0.038
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.038
sphingolipid biosynthetic process GO:0030148 18 0.038
negative regulation of cellular amine metabolic process GO:0033239 3 0.037
cellular lipid metabolic process GO:0044255 303 0.037
negative regulation of carbohydrate metabolic process GO:0045912 20 0.037
leukocyte differentiation GO:0002521 98 0.037
regulation of phospholipid scramblase activity GO:1900161 1 0.037
protein catabolic process GO:0030163 325 0.037
regulation of interleukin 10 secretion GO:2001179 4 0.037
regulation of protein stability GO:0031647 87 0.037
ubiquitin dependent protein catabolic process GO:0006511 206 0.036
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
negative regulation of ion transport GO:0043271 39 0.036
neuron projection development GO:0031175 106 0.036
Mouse
regulation of purine nucleotide catabolic process GO:0033121 205 0.035
embryo development GO:0009790 123 0.035
Fly
positive regulation of endothelial cell apoptotic process GO:2000353 8 0.035
cell projection organization GO:0030030 252 0.035
Mouse
peptidyl serine phosphorylation GO:0018105 101 0.035
adult locomotory behavior GO:0008344 1 0.035
hematopoietic or lymphoid organ development GO:0048534 186 0.035
regulation of angiogenesis GO:0045765 92 0.035
lamellipodium organization GO:0097581 30 0.035
nucleoside phosphate catabolic process GO:1901292 412 0.034
regulation of cardioblast differentiation GO:0051890 4 0.034
regulation of leukocyte activation GO:0002694 115 0.034
asymmetric stem cell division GO:0098722 1 0.034
Fly
cell growth GO:0016049 160 0.034
regulation of cell development GO:0060284 161 0.034
Mouse Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.033
positive regulation of vasoconstriction GO:0045907 3 0.033
regulation of rhodopsin mediated signaling pathway GO:0022400 1 0.033
neuron development GO:0048666 113 0.033
Mouse
monocarboxylic acid metabolic process GO:0032787 185 0.032
cellular polysaccharide metabolic process GO:0044264 27 0.032
positive regulation of protein secretion GO:0050714 60 0.032
glycogen metabolic process GO:0005977 22 0.032
purine nucleotide catabolic process GO:0006195 405 0.032
glycolipid metabolic process GO:0006664 27 0.032
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.032
regulation of cellular component biogenesis GO:0044087 281 0.031
peptidyl tyrosine phosphorylation GO:0018108 170 0.031
microtubule based process GO:0007017 210 0.031
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
positive regulation of cell proliferation GO:0008284 301 0.031
glycosphingolipid metabolic process GO:0006687 13 0.031
regulation of cell activation GO:0050865 125 0.031
positive regulation of cell division GO:0051781 59 0.031
positive regulation of neuron projection development GO:0010976 34 0.031
negative regulation of protein kinase activity GO:0006469 98 0.030
regulation of small gtpase mediated signal transduction GO:0051056 156 0.030
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.030
regulation of protein ubiquitination GO:0031396 95 0.030
organelle localization GO:0051640 84 0.030
Fly
regulation of secretion GO:0051046 194 0.030
regulation of fatty acid beta oxidation GO:0031998 8 0.030
positive regulation of organ growth GO:0046622 2 0.030
positive regulation of cell motility GO:2000147 177 0.030
interleukin 13 production GO:0032616 7 0.030
peripheral nervous system development GO:0007422 2 0.030
mitochondrion organization GO:0007005 156 0.029
cellular carbohydrate metabolic process GO:0044262 84 0.029
regulation of interleukin 5 production GO:0032674 6 0.029
alcohol metabolic process GO:0006066 114 0.029
single organismal cell cell adhesion GO:0016337 148 0.029
hyaluronan biosynthetic process GO:0030213 10 0.029
ribonucleotide catabolic process GO:0009261 405 0.029
ion transmembrane transport GO:0034220 338 0.029
neuroblast division GO:0055057 1 0.029
Mouse Fly
cell development GO:0048468 328 0.029
Mouse Fly
membrane budding GO:0006900 28 0.029
negative regulation of ion transmembrane transport GO:0034766 26 0.029
negative regulation of cellular component organization GO:0051129 235 0.029
regulation of protein localization GO:0032880 296 0.029
negative regulation of phosphate metabolic process GO:0045936 267 0.028
positive regulation of cell growth GO:0030307 48 0.028
axonogenesis GO:0007409 31 0.028
Mouse
positive regulation of cellular component biogenesis GO:0044089 158 0.028
regulation of protein complex assembly GO:0043254 147 0.028
pronephros development GO:0048793 2 0.028
nucleocytoplasmic transport GO:0006913 176 0.028
positive regulation of cell differentiation GO:0045597 211 0.028
Mouse
meiosis i GO:0007127 4 0.028
cellular response to dna damage stimulus GO:0006974 379 0.028
regulation of anatomical structure morphogenesis GO:0022603 286 0.028
Mouse
axis elongation GO:0003401 4 0.028
ethanolamine containing compound metabolic process GO:0042439 26 0.028
small gtpase mediated signal transduction GO:0007264 78 0.028
lymphocyte homeostasis GO:0002260 4 0.027
positive regulation of cellular catabolic process GO:0031331 284 0.027
positive regulation of locomotion GO:0040017 186 0.027
negative regulation of protein ubiquitination GO:0031397 35 0.027
regulation of glucose import GO:0046324 21 0.027
neurological system process GO:0050877 163 0.027
positive regulation of lamellipodium assembly GO:0010592 9 0.027
positive regulation of nucleotide metabolic process GO:0045981 230 0.027
positive regulation of phosphorylation GO:0042327 394 0.027
single organism membrane organization GO:0044802 268 0.027
glycosyl compound catabolic process GO:1901658 413 0.027
mrna 3 end processing GO:0031124 24 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.027
axon development GO:0061564 34 0.026
Mouse
regulation of dephosphorylation GO:0035303 96 0.026
renal system development GO:0072001 63 0.026
Fly
jnk cascade GO:0007254 80 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
carboxylic acid transport GO:0046942 63 0.026
negative regulation of kinase activity GO:0033673 106 0.025
cellular response to oxygen containing compound GO:1901701 276 0.025
positive regulation of lipid catabolic process GO:0050996 13 0.025
regulation of generation of precursor metabolites and energy GO:0043467 27 0.025
positive regulation of protein kinase activity GO:0045860 190 0.025
plasma membrane long chain fatty acid transport GO:0015911 5 0.025
organophosphate ester transport GO:0015748 32 0.025
Worm
cellular amide metabolic process GO:0043603 69 0.025
regulation of cell differentiation GO:0045595 393 0.025
Mouse Fly
cell type specific apoptotic process GO:0097285 125 0.025
system process GO:0003008 349 0.025
regulation of protein localization to plasma membrane GO:1903076 40 0.025
regulation of erk1 and erk2 cascade GO:0070372 99 0.025
positive regulation of cell development GO:0010720 92 0.025
Mouse
mitotic cell cycle process GO:1903047 286 0.024
regulation of cell motility GO:2000145 299 0.024
regulation of membrane potential GO:0042391 95 0.024
ribonucleoprotein complex assembly GO:0022618 78 0.024
cell aging GO:0007569 52 0.024
positive regulation of ras gtpase activity GO:0032320 117 0.024
epithelium migration GO:0090132 119 0.024
positive regulation of cytokine production GO:0001819 167 0.024
metal ion transport GO:0030001 272 0.024
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.024
circulatory system development GO:0072359 262 0.024
Fly
g1 s transition of mitotic cell cycle GO:0000082 78 0.024
plasma membrane organization GO:0007009 115 0.024
endothelial cell migration GO:0043542 86 0.023
associative learning GO:0008306 1 0.023
positive regulation of lymphocyte activation GO:0051251 73 0.023
golgi vesicle transport GO:0048193 80 0.023
regulation of rab gtpase activity GO:0032313 39 0.023
dna repair GO:0006281 198 0.023
granulocyte activation GO:0036230 10 0.023
negative regulation of protein catabolic process GO:0042177 59 0.023
regulation of glial cell apoptotic process GO:0034350 6 0.023
nucleoside catabolic process GO:0009164 408 0.023
regulation of lymphocyte activation GO:0051249 103 0.023
modification dependent macromolecule catabolic process GO:0043632 212 0.023
cellular response to organonitrogen compound GO:0071417 124 0.023
convergent extension GO:0060026 1 0.023
ion homeostasis GO:0050801 230 0.023
regulation of gtp catabolic process GO:0033124 180 0.023
mapk cascade GO:0000165 288 0.022
regulation of cell cycle GO:0051726 393 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
negative regulation of transport GO:0051051 176 0.022
rna 3 end processing GO:0031123 35 0.022
purine nucleoside catabolic process GO:0006152 398 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
response to organonitrogen compound GO:0010243 156 0.022
positive regulation of cell cycle GO:0045787 140 0.022
protein targeting to nucleus GO:0044744 104 0.022
blood vessel endothelial cell migration GO:0043534 42 0.022
nuclear transport GO:0051169 179 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.022
cellular response to hormone stimulus GO:0032870 125 0.022
regulation of notch signaling pathway GO:0008593 18 0.021
Mouse
positive regulation of cellular component movement GO:0051272 181 0.021
chemotaxis GO:0006935 157 0.021
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.021
regulation of lamellipodium organization GO:1902743 19 0.021
negative regulation of growth GO:0045926 97 0.021
regulation of nucleotide catabolic process GO:0030811 205 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
negative regulation of cellular catabolic process GO:0031330 83 0.021
cellular senescence GO:0090398 34 0.021
regulation of protein transport GO:0051223 213 0.021
reactive oxygen species metabolic process GO:0072593 75 0.021
regulation of leukocyte differentiation GO:1902105 61 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
nuclear transcribed mrna catabolic process GO:0000956 48 0.021
tube development GO:0035295 125 0.021
Mouse Fly
negative regulation of catabolic process GO:0009895 104 0.021
positive regulation of oxidoreductase activity GO:0051353 26 0.020
positive regulation of cell projection organization GO:0031346 64 0.020
reproductive structure development GO:0048608 55 0.020
positive regulation of intracellular transport GO:0032388 104 0.020
cell division GO:0051301 168 0.020
Mouse Fly
hexose metabolic process GO:0019318 55 0.020
embryonic morphogenesis GO:0048598 85 0.020
phospholipid metabolic process GO:0006644 99 0.020

NUMB disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.072
nervous system disease DOID:863 431 0.072
cancer DOID:162 167 0.070
disease of cellular proliferation DOID:14566 174 0.070
organ system cancer DOID:0050686 164 0.070
disease of metabolism DOID:0014667 295 0.034
disease of mental health DOID:150 70 0.032
cognitive disorder DOID:1561 29 0.025
neurodegenerative disease DOID:1289 102 0.024
tauopathy DOID:680 16 0.023