Homo sapiens

26 known processes

TDP2

tyrosyl-DNA phosphodiesterase 2

(Aliases: AD022,MGC111021,TTRAP,dJ30M3.3,MGC9099,EAP2)

TDP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organophosphate catabolic process GO:0046434 430 0.439
nucleoside triphosphate catabolic process GO:0009143 394 0.428
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.368
cellular response to acidic ph GO:0071468 3 0.270
nucleoside catabolic process GO:0009164 408 0.262
ribonucleotide catabolic process GO:0009261 405 0.259
ribonucleoside triphosphate metabolic process GO:0009199 412 0.251
purine ribonucleotide catabolic process GO:0009154 404 0.251
glycosyl compound catabolic process GO:1901658 413 0.248
ribonucleoside catabolic process GO:0042454 406 0.207
purine containing compound catabolic process GO:0072523 411 0.198
purine nucleoside triphosphate catabolic process GO:0009146 392 0.190
endosome organization GO:0007032 20 0.188
nucleoside triphosphate metabolic process GO:0009141 422 0.174
purine ribonucleoside catabolic process GO:0046130 398 0.167
constitutive secretory pathway GO:0045054 3 0.160
post embryonic development GO:0009791 2 0.155
ribonucleoside triphosphate catabolic process GO:0009203 391 0.149
nucleoside phosphate catabolic process GO:1901292 412 0.141
cell fate determination GO:0001709 3 0.139
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.138
nucleotide catabolic process GO:0009166 408 0.131
purine nucleoside catabolic process GO:0006152 398 0.118
purine ribonucleoside metabolic process GO:0046128 437 0.109
endosomal transport GO:0016197 129 0.104
endomembrane system organization GO:0010256 196 0.094
purine nucleoside triphosphate metabolic process GO:0009144 412 0.090
mrna processing GO:0006397 133 0.085
positive regulation of developmental process GO:0051094 314 0.083
cytoplasmic transport GO:0016482 379 0.077
regulation of oocyte development GO:0060281 1 0.076
golgi vesicle fusion to target membrane GO:0048210 2 0.075
intracellular protein transport GO:0006886 270 0.074
cardiovascular system development GO:0072358 262 0.067
purine nucleotide catabolic process GO:0006195 405 0.064
female gamete generation GO:0007292 2 0.061
rab protein signal transduction GO:0032482 4 0.060
neuromuscular junction development GO:0007528 3 0.058
regulation of nucleoside metabolic process GO:0009118 209 0.055
membrane organization GO:0061024 292 0.055
positive regulation of cell differentiation GO:0045597 211 0.054
late endosome to vacuole transport GO:0045324 2 0.051
response to other organism GO:0051707 261 0.050
single organism cellular localization GO:1902580 332 0.050
response to abiotic stimulus GO:0009628 336 0.050
oogenesis GO:0048477 2 0.049
vasculature development GO:0001944 181 0.048
organelle assembly GO:0070925 176 0.047
growth GO:0040007 202 0.047
positive regulation of catabolic process GO:0009896 310 0.046
epithelium development GO:0060429 227 0.045
gtp catabolic process GO:0006184 237 0.044
guanosine containing compound metabolic process GO:1901068 244 0.044
single organism membrane fusion GO:0044801 37 0.044
alcohol metabolic process GO:0006066 114 0.043
multivesicular body organization GO:0036257 2 0.042
cilium morphogenesis GO:0060271 75 0.041
circulatory system development GO:0072359 262 0.040
single organism membrane organization GO:0044802 268 0.040
regulation of golgi to plasma membrane protein transport GO:0042996 3 0.040
multicellular organismal aging GO:0010259 3 0.039
regulation of cell morphogenesis GO:0022604 153 0.036
nucleoside monophosphate catabolic process GO:0009125 159 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.035
microtubule based process GO:0007017 210 0.035
cell fate commitment involved in pattern specification GO:0060581 1 0.035
plasma membrane organization GO:0007009 115 0.034
positive regulation of cell development GO:0010720 92 0.033
cellular amine metabolic process GO:0044106 41 0.033
positive regulation of axon extension GO:0045773 4 0.033
regulation of anatomical structure morphogenesis GO:0022603 286 0.033
cell morphogenesis GO:0000902 296 0.032
glycerolipid metabolic process GO:0046486 107 0.032
secretion GO:0046903 254 0.031
anatomical structure formation involved in morphogenesis GO:0048646 284 0.031
cellular component morphogenesis GO:0032989 314 0.031
regulation of neuronal synaptic plasticity GO:0048168 1 0.030
rna splicing via transesterification reactions GO:0000375 90 0.030
embryo development GO:0009790 123 0.030
rna splicing GO:0008380 131 0.029
vesicle organization GO:0016050 62 0.029
regulation of cell maturation GO:1903429 3 0.029
blood vessel development GO:0001568 172 0.028
regulation of cellular response to growth factor stimulus GO:0090287 76 0.027
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.027
positive regulation of growth GO:0045927 58 0.026
protein localization to membrane GO:0072657 160 0.026
chemical homeostasis GO:0048878 306 0.026
mrna metabolic process GO:0016071 175 0.025
myoblast fusion GO:0007520 1 0.025
cell development GO:0048468 328 0.024
protein localization to plasma membrane GO:0072659 93 0.024
neurotransmitter secretion GO:0007269 4 0.024
regulation of growth GO:0040008 165 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
establishment of protein localization to membrane GO:0090150 121 0.023
locomotory behavior GO:0007626 1 0.023
cilium organization GO:0044782 68 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
segmentation GO:0035282 4 0.022
golgi vesicle transport GO:0048193 80 0.022
macromolecule methylation GO:0043414 97 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
dephosphorylation GO:0016311 209 0.021
immune response GO:0006955 307 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
response to external biotic stimulus GO:0043207 261 0.021
ras protein signal transduction GO:0007265 73 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
regulation of protein catabolic process GO:0042176 155 0.020
retrograde transport endosome to golgi GO:0042147 45 0.020
nucleoside monophosphate metabolic process GO:0009123 191 0.019
atp metabolic process GO:0046034 176 0.019
positive regulation of gtpase activity GO:0043547 166 0.019
protein localization to synapse GO:0035418 2 0.018
microtubule cytoskeleton organization GO:0000226 176 0.018
blood vessel morphogenesis GO:0048514 162 0.018
receptor mediated endocytosis GO:0006898 84 0.018
dna conformation change GO:0071103 113 0.018
cellular protein complex assembly GO:0043623 188 0.018
neuron projection development GO:0031175 106 0.018
cell cell junction organization GO:0045216 69 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
cell morphogenesis involved in differentiation GO:0000904 144 0.018
oocyte differentiation GO:0009994 2 0.017
cell projection morphogenesis GO:0048858 129 0.017
secretion by cell GO:0032940 226 0.017
negative regulation of growth GO:0045926 97 0.017
response to biotic stimulus GO:0009607 276 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.017
organ formation GO:0048645 3 0.016
multi organism cellular process GO:0044764 156 0.016
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.016
organophosphate biosynthetic process GO:0090407 163 0.016
regulation of cell growth GO:0001558 135 0.016
amine metabolic process GO:0009308 44 0.016
cellular response to growth factor stimulus GO:0071363 197 0.015
vacuolar transport GO:0007034 34 0.015
lipid metabolic process GO:0006629 381 0.015
actin filament based process GO:0030029 224 0.015
retrograde transport endosome to plasma membrane GO:1990126 3 0.015
developmental growth GO:0048589 48 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.015
generation of neurons GO:0048699 152 0.014
cell junction organization GO:0034330 79 0.014
stem cell development GO:0048864 69 0.014
cell part morphogenesis GO:0032990 137 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
neuron development GO:0048666 113 0.014
cellular response to external stimulus GO:0071496 111 0.014
early endosome to golgi transport GO:0034498 3 0.014
negative regulation of multi organism process GO:0043901 92 0.014
positive regulation of cell cycle process GO:0090068 106 0.014
oocyte development GO:0048599 1 0.014
regulation of protein transport GO:0051223 213 0.014
determination of adult lifespan GO:0008340 2 0.014
cellular ketone metabolic process GO:0042180 80 0.013
rna processing GO:0006396 255 0.013
cellular component disassembly GO:0022411 92 0.013
tripartite regional subdivision GO:0007351 2 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
reproductive process GO:0022414 106 0.013
stem cell division GO:0017145 2 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
phospholipid metabolic process GO:0006644 99 0.013
sulfur compound metabolic process GO:0006790 101 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
positive regulation of dendrite morphogenesis GO:0050775 3 0.013
negative regulation of developmental process GO:0051093 247 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
gtp metabolic process GO:0046039 239 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.013
glycerophospholipid metabolic process GO:0006650 84 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
positive regulation of nervous system development GO:0051962 54 0.013
regulation of cell development GO:0060284 161 0.012
interspecies interaction between organisms GO:0044419 156 0.012
organic hydroxy compound metabolic process GO:1901615 147 0.012
neurogenesis GO:0022008 169 0.012
cell growth GO:0016049 160 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
anterior posterior axis specification GO:0009948 2 0.012
regulation of gtpase activity GO:0043087 180 0.012
angiogenesis GO:0001525 147 0.012
compound eye development GO:0048749 1 0.012
positive regulation of transport GO:0051050 336 0.012
positive regulation of cytoplasmic transport GO:1903651 82 0.012
positive regulation of neurogenesis GO:0050769 49 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
mitotic cell cycle GO:0000278 326 0.011
regulation of proteolysis GO:0030162 293 0.011
regulation of intracellular transport GO:0032386 195 0.011
lipid transport GO:0006869 90 0.011
cardiac muscle tissue development GO:0048738 39 0.011
positive regulation of protein transport GO:0051222 135 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
response to oxygen containing compound GO:1901700 369 0.011
ameboidal type cell migration GO:0001667 135 0.011
mrna splicing via spliceosome GO:0000398 89 0.011
viral process GO:0016032 146 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
regulation of vesicle mediated transport GO:0060627 130 0.010
purine nucleoside monophosphate metabolic process GO:0009126 186 0.010
cellular response to ph GO:0071467 9 0.010
associative learning GO:0008306 1 0.010
cellular homeostasis GO:0019725 196 0.010
multi organism reproductive process GO:0044703 54 0.010
sequestering of metal ion GO:0051238 24 0.010
aging GO:0007568 66 0.010

TDP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.021
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
central nervous system disease DOID:331 186 0.014
nervous system disease DOID:863 431 0.014