Homo sapiens

19 known processes

ADAMTS13

ADAM metallopeptidase with thrombospondin type 1 motif, 13

(Aliases: FLJ42993,vWF-CP,MGC118900,TTP,VWFCP,DKFZp434C2322,MGC118899,C9orf8)

ADAMTS13 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
metal ion transport GO:0030001 272 0.076
cation transport GO:0006812 331 0.076
ion transmembrane transport GO:0034220 338 0.070
cellular amino acid metabolic process GO:0006520 116 0.067
cellular ketone metabolic process GO:0042180 80 0.064
post embryonic development GO:0009791 2 0.059
nucleoside triphosphate metabolic process GO:0009141 422 0.054
ribonucleoside triphosphate metabolic process GO:0009199 412 0.054
nucleoside catabolic process GO:0009164 408 0.052
purine nucleotide catabolic process GO:0006195 405 0.051
amine metabolic process GO:0009308 44 0.050
regulation of cell motility GO:2000145 299 0.050
ribonucleoside triphosphate catabolic process GO:0009203 391 0.050
cellular homeostasis GO:0019725 196 0.048
organophosphate catabolic process GO:0046434 430 0.048
nucleoside phosphate catabolic process GO:1901292 412 0.048
purine nucleoside triphosphate metabolic process GO:0009144 412 0.046
ribonucleotide catabolic process GO:0009261 405 0.046
purine nucleoside triphosphate catabolic process GO:0009146 392 0.046
nucleoside triphosphate catabolic process GO:0009143 394 0.044
cation transmembrane transport GO:0098655 238 0.044
purine containing compound catabolic process GO:0072523 411 0.044
regulation of cellular amino acid metabolic process GO:0006521 6 0.043
glycosyl compound catabolic process GO:1901658 413 0.043
regulation of purine nucleotide metabolic process GO:1900542 264 0.043
regulation of cellular amine metabolic process GO:0033238 11 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
response to oxygen containing compound GO:1901700 369 0.041
purine ribonucleotide catabolic process GO:0009154 404 0.041
g protein coupled receptor signaling pathway GO:0007186 207 0.041
biological adhesion GO:0022610 331 0.040
Human
membrane organization GO:0061024 292 0.040
defense response GO:0006952 315 0.040
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.039
regulation of nucleotide metabolic process GO:0006140 269 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.039
negative regulation of cell death GO:0060548 345 0.039
regulation of cellular ketone metabolic process GO:0010565 50 0.038
purine ribonucleoside catabolic process GO:0046130 398 0.037
micturition GO:0060073 3 0.037
regulation of anatomical structure morphogenesis GO:0022603 286 0.037
Human
response to abiotic stimulus GO:0009628 336 0.037
cell adhesion GO:0007155 325 0.036
Human
regulation of cellular component movement GO:0051270 334 0.036
purine ribonucleoside metabolic process GO:0046128 437 0.036
positive regulation of nucleotide metabolic process GO:0045981 230 0.036
regulation of locomotion GO:0040012 329 0.035
positive regulation of transport GO:0051050 336 0.035
positive regulation of phosphorylation GO:0042327 394 0.035
system process GO:0003008 349 0.035
vesicle mediated transport GO:0016192 371 0.034
immune response GO:0006955 307 0.034
cytoplasmic transport GO:0016482 379 0.034
cell projection organization GO:0030030 252 0.034
nucleotide catabolic process GO:0009166 408 0.033
synaptic transmission involved in micturition GO:0060084 2 0.033
negative regulation of apoptotic process GO:0043066 316 0.033
cellular amine metabolic process GO:0044106 41 0.033
chemical homeostasis GO:0048878 306 0.032
cardiovascular system development GO:0072358 262 0.032
protein maturation GO:0051604 233 0.032
Human
regulation of cell migration GO:0030334 289 0.032
rho protein signal transduction GO:0007266 26 0.031
purine nucleoside catabolic process GO:0006152 398 0.031
protein processing GO:0016485 226 0.031
Human
locomotory behavior GO:0007626 1 0.031
positive regulation of cellular amine metabolic process GO:0033240 7 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
oxidation reduction process GO:0055114 396 0.030
ribonucleoside catabolic process GO:0042454 406 0.030
cytokine production GO:0001816 247 0.030
Human
single organism membrane organization GO:0044802 268 0.029
nervous system development GO:0007399 293 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
ras protein signal transduction GO:0007265 73 0.029
lipid metabolic process GO:0006629 381 0.029
cell development GO:0048468 328 0.028
memory GO:0007613 3 0.028
cellular response to endogenous stimulus GO:0071495 336 0.028
Human
guanosine containing compound metabolic process GO:1901068 244 0.028
multicellular organismal aging GO:0010259 3 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
positive regulation of cellular component organization GO:0051130 376 0.027
transmembrane transport GO:0055085 399 0.027
determination of adult lifespan GO:0008340 2 0.027
regulation of nucleotide catabolic process GO:0030811 205 0.027
calcium ion transport GO:0006816 147 0.026
negative regulation of acetylcholine gated cation channel activity GO:1903049 1 0.026
vasculature development GO:0001944 181 0.026
circulatory system development GO:0072359 262 0.026
inorganic ion transmembrane transport GO:0098660 231 0.026
regulation of purine nucleotide catabolic process GO:0033121 205 0.026
positive regulation of catabolic process GO:0009896 310 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.025
organophosphate biosynthetic process GO:0090407 163 0.025
small gtpase mediated signal transduction GO:0007264 78 0.025
gtp metabolic process GO:0046039 239 0.025
regulation of cellular component biogenesis GO:0044087 281 0.025
cell substrate adhesion GO:0031589 132 0.025
Human
negative regulation of programmed cell death GO:0043069 321 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.025
divalent metal ion transport GO:0070838 152 0.025
guanosine containing compound catabolic process GO:1901069 239 0.025
neuromuscular junction development GO:0007528 3 0.025
regulation of acetylcholine gated cation channel activity GO:1903048 1 0.024
positive regulation of cell motility GO:2000147 177 0.024
carbohydrate metabolic process GO:0005975 207 0.024
positive regulation of developmental process GO:0051094 314 0.024
positive regulation of hydrolase activity GO:0051345 331 0.024
signal transduction by phosphorylation GO:0023014 297 0.024
cellular lipid metabolic process GO:0044255 303 0.024
ion homeostasis GO:0050801 230 0.023
inorganic cation transmembrane transport GO:0098662 194 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
protein modification by small protein conjugation GO:0032446 342 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
positive regulation of protein phosphorylation GO:0001934 313 0.023
regulation of mapk cascade GO:0043408 262 0.023
cellular protein catabolic process GO:0044257 261 0.023
Human
gtp catabolic process GO:0006184 237 0.023
cellular ion homeostasis GO:0006873 168 0.023
nitrogen compound transport GO:0071705 191 0.022
female gamete generation GO:0007292 2 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.022
regulation of kinase activity GO:0043549 314 0.022
regulation of cellular response to stress GO:0080135 244 0.021
cell matrix adhesion GO:0007160 85 0.021
Human
cellular chemical homeostasis GO:0055082 180 0.021
positive regulation of immune system process GO:0002684 283 0.021
divalent inorganic cation transport GO:0072511 158 0.021
reactive oxygen species metabolic process GO:0072593 75 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
cellular cation homeostasis GO:0030003 163 0.020
epithelium development GO:0060429 227 0.020
Human
cellular response to dna damage stimulus GO:0006974 379 0.020
single organism cellular localization GO:1902580 332 0.020
angiogenesis GO:0001525 147 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
cellular component morphogenesis GO:0032989 314 0.020
regulation of gtpase activity GO:0043087 180 0.020
regulation of gtp catabolic process GO:0033124 180 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
negative regulation of multicellular organismal process GO:0051241 317 0.020
Human
secretion GO:0046903 254 0.019
oogenesis GO:0048477 2 0.019
monovalent inorganic cation transport GO:0015672 128 0.019
apoptotic signaling pathway GO:0097190 268 0.019
regulation of cell differentiation GO:0045595 393 0.019
Human
secretion by cell GO:0032940 226 0.019
hormone secretion GO:0046879 65 0.019
protein catabolic process GO:0030163 325 0.019
Human
regulation of secretion GO:0051046 194 0.019
response to external biotic stimulus GO:0043207 261 0.019
segmentation GO:0035282 4 0.019
wnt signaling pathway GO:0016055 156 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
nucleotide biosynthetic process GO:0009165 109 0.019
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
blood vessel development GO:0001568 172 0.018
positive regulation of cellular component movement GO:0051272 181 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.018
regulation of transferase activity GO:0051338 355 0.018
regulation of defense response GO:0031347 154 0.018
Human
associative learning GO:0008306 1 0.018
positive regulation of locomotion GO:0040017 186 0.018
hindbrain development GO:0030902 3 0.018
protein ubiquitination GO:0016567 314 0.018
regulation of protein localization GO:0032880 296 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
Human
regulation of cytokine production GO:0001817 232 0.018
regulation of protein kinase activity GO:0045859 289 0.018
negative regulation of hydrolase activity GO:0051346 182 0.017
ribonucleoside monophosphate metabolic process GO:0009161 187 0.017
maintenance of location GO:0051235 112 0.017
cell cell signaling GO:0007267 155 0.017
striated muscle contraction GO:0006941 52 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
response to inorganic substance GO:0010035 127 0.017
mating GO:0007618 1 0.017
blood vessel morphogenesis GO:0048514 162 0.017
positive regulation of cell migration GO:0030335 172 0.017
negative regulation of protein modification process GO:0031400 200 0.017
response to other organism GO:0051707 261 0.017
intracellular protein transport GO:0006886 270 0.017
blastoderm segmentation GO:0007350 2 0.017
regulation of secretion by cell GO:1903530 177 0.017
single organism cell adhesion GO:0098602 179 0.017
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
atp metabolic process GO:0046034 176 0.016
dna repair GO:0006281 198 0.016
nerve development GO:0021675 4 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
cellular metal ion homeostasis GO:0006875 146 0.016
regulation of cell cycle GO:0051726 393 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
rhythmic behavior GO:0007622 2 0.016
cell morphogenesis GO:0000902 296 0.016
negative regulation of developmental process GO:0051093 247 0.016
Human
cellular response to oxygen containing compound GO:1901701 276 0.016
divalent inorganic cation homeostasis GO:0072507 136 0.016
anion transport GO:0006820 161 0.016
anatomical structure homeostasis GO:0060249 100 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
mapk cascade GO:0000165 288 0.016
regulation of response to external stimulus GO:0032101 222 0.016
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
Human
regulation of vasculature development GO:1901342 97 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
visual behavior GO:0007632 2 0.016
cation homeostasis GO:0055080 189 0.015
response to oxygen levels GO:0070482 100 0.015
regulation of protein maturation GO:1903317 150 0.015
regulation of proteolysis GO:0030162 293 0.015
cyclic nucleotide metabolic process GO:0009187 82 0.015
visual learning GO:0008542 1 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
response to hypoxia GO:0001666 96 0.015
mitotic cell cycle GO:0000278 326 0.015
protein localization to organelle GO:0033365 280 0.015
metal ion homeostasis GO:0055065 169 0.015
response to biotic stimulus GO:0009607 276 0.015
regulation of protein transport GO:0051223 213 0.015
actin filament based process GO:0030029 224 0.015
taxis GO:0042330 157 0.015
regulation of hormone levels GO:0010817 125 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
organic hydroxy compound metabolic process GO:1901615 147 0.015
nucleoside phosphate biosynthetic process GO:1901293 109 0.015
response to metal ion GO:0010038 84 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
neurogenesis GO:0022008 169 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
regulation of membrane potential GO:0042391 95 0.015
endomembrane system organization GO:0010256 196 0.015
positive regulation of kinase activity GO:0033674 204 0.015
regulation of cell cycle process GO:0010564 266 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.014
positive regulation of cell cycle GO:0045787 140 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
regulation of protein processing GO:0070613 150 0.014
response to lipid GO:0033993 206 0.014
peptidyl tyrosine modification GO:0018212 170 0.014
microtubule based process GO:0007017 210 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
positive regulation of transferase activity GO:0051347 227 0.014
regulation of angiogenesis GO:0045765 92 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
negative regulation of organelle organization GO:0010639 126 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
innate immune response GO:0045087 178 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
histone modification GO:0016570 251 0.014
metencephalon development GO:0022037 2 0.014
embryonic camera type eye development GO:0031076 2 0.014
circadian behavior GO:0048512 2 0.014
response to hormone GO:0009725 175 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
response to cytokine GO:0034097 232 0.014
Human
ameboidal type cell migration GO:0001667 135 0.014
regulation of peptidase activity GO:0052547 180 0.013
oocyte development GO:0048599 1 0.013
synaptic transmission cholinergic GO:0007271 2 0.013
negative regulation of protein maturation GO:1903318 142 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.013
negative regulation of protein processing GO:0010955 142 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
response to extracellular stimulus GO:0009991 85 0.013
mitotic cell cycle process GO:1903047 286 0.013
generation of neurons GO:0048699 152 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
dephosphorylation GO:0016311 209 0.013
cell part morphogenesis GO:0032990 137 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
regulation of protein complex assembly GO:0043254 147 0.013
response to growth factor GO:0070848 205 0.013
Human
protein oligomerization GO:0051259 173 0.013
postsynaptic membrane organization GO:0001941 2 0.013
small molecule catabolic process GO:0044282 92 0.013
actin cytoskeleton organization GO:0030036 207 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
positive regulation of vascular endothelial growth factor signaling pathway GO:1900748 3 0.013
Human
regulation of rho protein signal transduction GO:0035023 79 0.013
signal release GO:0023061 70 0.013
endocytosis GO:0006897 159 0.013
protein targeting GO:0006605 187 0.013
hormone transport GO:0009914 68 0.013
response to nutrient levels GO:0031667 81 0.013
cellular protein complex assembly GO:0043623 188 0.012
epithelial cell migration GO:0010631 119 0.012
tissue morphogenesis GO:0048729 96 0.012
Human
negative regulation of cellular component movement GO:0051271 106 0.012
purine nucleotide biosynthetic process GO:0006164 84 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
negative regulation of proteolysis GO:0045861 132 0.012
chemotaxis GO:0006935 157 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
anterior posterior axis specification GO:0009948 2 0.012
regulation of anatomical structure size GO:0090066 101 0.012
response to radiation GO:0009314 151 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
response to nitrogen compound GO:1901698 184 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
tissue migration GO:0090130 119 0.012
growth GO:0040007 202 0.012
adult locomotory behavior GO:0008344 1 0.012
peripheral nervous system development GO:0007422 2 0.012
cell growth GO:0016049 160 0.012
multicellular organismal homeostasis GO:0048871 67 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
neurological system process GO:0050877 163 0.012
negative regulation of transferase activity GO:0051348 124 0.012
central nervous system development GO:0007417 123 0.012
cerebellum development GO:0021549 2 0.012
negative regulation of locomotion GO:0040013 118 0.012
ribose phosphate biosynthetic process GO:0046390 82 0.012
motor neuron axon guidance GO:0008045 2 0.012
organelle assembly GO:0070925 176 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
muscle contraction GO:0006936 73 0.012
plasma membrane organization GO:0007009 115 0.012
cell division GO:0051301 168 0.012
endosomal transport GO:0016197 129 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
salivary gland morphogenesis GO:0007435 4 0.012
spermatid differentiation GO:0048515 4 0.012
glycoprotein metabolic process GO:0009100 110 0.012
Human
sequestering of metal ion GO:0051238 24 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
regulation of ion transport GO:0043269 189 0.012
muscle cell cellular homeostasis GO:0046716 3 0.012
leukocyte migration GO:0050900 107 0.012
cellular response to lipid GO:0071396 127 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
blood coagulation GO:0007596 76 0.012
Human
calcium ion homeostasis GO:0055074 122 0.011
circulatory system process GO:0003013 113 0.011
regulation of homeostatic process GO:0032844 121 0.011
organ morphogenesis GO:0009887 147 0.011
cellular calcium ion homeostasis GO:0006874 117 0.011
negative regulation of cell motility GO:2000146 104 0.011
phospholipid metabolic process GO:0006644 99 0.011
sensory perception GO:0007600 103 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
cell projection assembly GO:0030031 126 0.011
ribonucleoside monophosphate catabolic process GO:0009158 158 0.011
second messenger mediated signaling GO:0019932 78 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
atp catabolic process GO:0006200 157 0.011
positive regulation of secretion GO:0051047 116 0.011
tripartite regional subdivision GO:0007351 2 0.011
receptor metabolic process GO:0043112 81 0.011
response to oxidative stress GO:0006979 121 0.011
negative regulation of transport GO:0051051 176 0.011
inner ear morphogenesis GO:0042472 4 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
multi organism cellular process GO:0044764 156 0.011
regulation of canonical wnt signaling pathway GO:0060828 88 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
engulfment of apoptotic cell GO:0043652 2 0.011
cellular divalent inorganic cation homeostasis GO:0072503 128 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
cell cycle phase transition GO:0044770 173 0.011
response to tumor necrosis factor GO:0034612 76 0.011
Human
response to decreased oxygen levels GO:0036293 96 0.011
oocyte differentiation GO:0009994 2 0.011
regulation of chemotaxis GO:0050920 74 0.011
immune system development GO:0002520 195 0.011
response to fungus GO:0009620 4 0.011
epithelium migration GO:0090132 119 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
organic acid catabolic process GO:0016054 71 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of cell projection organization GO:0031344 107 0.011
regulation of cell adhesion GO:0030155 166 0.011
Human
negative regulation of protein phosphorylation GO:0001933 140 0.010
neuron differentiation GO:0030182 138 0.010
peptide transport GO:0015833 74 0.010
carboxylic acid catabolic process GO:0046395 71 0.010
regulation of dna metabolic process GO:0051052 153 0.010
single organismal cell cell adhesion GO:0016337 148 0.010
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.010
hemopoiesis GO:0030097 180 0.010
regulation of body fluid levels GO:0050878 99 0.010
Human
regulation of cell development GO:0060284 161 0.010
regulation of dephosphorylation GO:0035303 96 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
neuroblast proliferation GO:0007405 4 0.010
protein modification by small protein removal GO:0070646 92 0.010
negative regulation of cell migration GO:0030336 102 0.010
protein localization to membrane GO:0072657 160 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
Human
embryonic viscerocranium morphogenesis GO:0048703 1 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
monocarboxylic acid metabolic process GO:0032787 185 0.010
neuron development GO:0048666 113 0.010
regulation of behavior GO:0050795 82 0.010

ADAMTS13 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.033
sensory system disease DOID:0050155 203 0.030
nervous system disease DOID:863 431 0.030
eye and adnexa disease DOID:1492 150 0.027
eye disease DOID:5614 149 0.023
musculoskeletal system disease DOID:17 223 0.019
inherited metabolic disorder DOID:655 242 0.016
disease of cellular proliferation DOID:14566 174 0.015
retinal disease DOID:5679 118 0.015
cancer DOID:162 167 0.013
organ system cancer DOID:0050686 164 0.013
heart disease DOID:114 68 0.013
cardiovascular system disease DOID:1287 106 0.013
immune system disease DOID:2914 155 0.013
connective tissue disease DOID:65 109 0.012
central nervous system disease DOID:331 186 0.011
neurodegenerative disease DOID:1289 102 0.011