|
|
positive regulation of actin nucleation
|
GO:0051127 |
6 |
1.000
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
1.000
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
Rat |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
1.000
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
1.000
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.999
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.999
|
Mouse Rat |
|
|
positive regulation of arp2 3 complex mediated actin nucleation
|
GO:2000601 |
5 |
0.999
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.998
|
Human Mouse Rat Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.998
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.998
|
Human Mouse Rat Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.997
|
Human Mouse Rat Fly |
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.996
|
Rat |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.996
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.996
|
Human Rat |
|
|
cell development
|
GO:0048468 |
328 |
0.995
|
Human Mouse Rat Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.994
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.994
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.994
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.992
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.991
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.988
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.988
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.987
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.987
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.986
|
Worm |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.985
|
Mouse Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.985
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.985
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.984
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.983
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.983
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.983
|
Mouse |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.982
|
Mouse |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.979
|
Mouse Rat |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.979
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.979
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.976
|
Mouse Rat |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.976
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.975
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.973
|
Mouse |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.972
|
Rat |
|
|
growth
|
GO:0040007 |
202 |
0.971
|
Mouse Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.971
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.971
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.971
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.969
|
Human Mouse Rat Fly |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.966
|
Worm |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.965
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.965
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.964
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.963
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.960
|
Fly |
|
|
taxis
|
GO:0042330 |
157 |
0.959
|
Fly |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.954
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.953
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.953
|
Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.952
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.952
|
Mouse Fly |
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.949
|
Worm |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.949
|
Mouse Rat |
|
|
nervous system development
|
GO:0007399 |
293 |
0.948
|
Human Mouse Rat Fly |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.946
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.945
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.944
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.943
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.941
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.940
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.936
|
Rat |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.936
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.936
|
Mouse |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.936
|
Mouse Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.935
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.934
|
Mouse Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.928
|
Rat |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.928
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.926
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.925
|
Mouse Rat |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.923
|
Mouse |
|
|
defense response
|
GO:0006952 |
315 |
0.921
|
Worm |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.921
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.921
|
Mouse Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.916
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.916
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.914
|
Mouse Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.912
|
Fly |
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.912
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
6 |
0.909
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.909
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.901
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.900
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.899
|
Mouse Fly |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.896
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.895
|
Mouse Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.894
|
Human Rat |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.889
|
Mouse |
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.887
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.884
|
Mouse Worm |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.884
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.883
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.883
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.876
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.869
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.865
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.861
|
Mouse |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.857
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.855
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.855
|
Mouse Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.854
|
Mouse Worm |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.853
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.850
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.850
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.850
|
Rat |
|
|
oogenesis
|
GO:0048477 |
2 |
0.844
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.840
|
Human Mouse Rat |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.839
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.839
|
Mouse Worm |
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.838
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.837
|
Mouse |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.836
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.832
|
Mouse Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.829
|
Human Mouse Rat |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.829
|
Human Rat |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.823
|
Mouse Worm |
|
|
system process
|
GO:0003008 |
349 |
0.821
|
Mouse Rat |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.821
|
Mouse Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.820
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.811
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.810
|
Fly |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.809
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.809
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.808
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.802
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.802
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.800
|
Mouse |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.797
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.797
|
Rat |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.771
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.770
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.766
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.764
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.763
|
Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.760
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.760
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.750
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.749
|
Rat |
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.749
|
Mouse |
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.749
|
Human Rat |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.749
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.743
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.739
|
Mouse |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.737
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.735
|
Mouse Fly |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.734
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.729
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.728
|
|
|
|
regulation of apoptotic cell clearance
|
GO:2000425 |
5 |
0.728
|
Worm |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.724
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.723
|
Human Rat |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.723
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.721
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.717
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.716
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.714
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.711
|
Mouse Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.709
|
Mouse |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.707
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.701
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.700
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.700
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.696
|
Human Rat |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.696
|
Fly |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.696
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.695
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.694
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.690
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.690
|
Mouse |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.687
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.686
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.684
|
Mouse |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.681
|
Mouse |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.681
|
Human Rat |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.679
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.679
|
Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.679
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.678
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.678
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.674
|
Human Rat |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.674
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.664
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.659
|
Worm |
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.653
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.641
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.641
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.637
|
Mouse Worm |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.637
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.636
|
Rat |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.632
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.630
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.628
|
|
|
|
parathyroid gland development
|
GO:0060017 |
2 |
0.624
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.620
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.612
|
Mouse |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.612
|
Rat |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.610
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.607
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.603
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.597
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.597
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.596
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.594
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.592
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.586
|
Rat |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.582
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.581
|
Mouse |
|
|
immune system development
|
GO:0002520 |
195 |
0.580
|
Mouse |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.578
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.575
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.575
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.573
|
Rat |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.571
|
|
|
|
neuron projection guidance
|
GO:0097485 |
12 |
0.570
|
Fly |
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.565
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.565
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.561
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.557
|
Fly |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.557
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.555
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.555
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.551
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.550
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.549
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.547
|
Mouse |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.544
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.543
|
Mouse Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.542
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.541
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.540
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.538
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.531
|
Mouse Worm |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.528
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.524
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.523
|
|
|
|
cellular response to camp
|
GO:0071320 |
21 |
0.522
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.521
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.516
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.513
|
|
|
|
reciprocal meiotic recombination
|
GO:0007131 |
4 |
0.510
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.504
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.496
|
Fly |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.494
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.491
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.488
|
Human Rat |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.484
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.473
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.473
|
Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.471
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.469
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.469
|
Mouse Rat |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.467
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.463
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.459
|
Rat |
|
|
dna recombination
|
GO:0006310 |
77 |
0.456
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.455
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.453
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.453
|
Mouse |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.453
|
Worm Fly |
|
|
oocyte development
|
GO:0048599 |
1 |
0.452
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.450
|
Mouse |
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.449
|
Worm |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.447
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.446
|
Human Mouse Rat Fly |
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.441
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.440
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.438
|
Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.438
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.436
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.430
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.428
|
Mouse |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.428
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.422
|
|
|
|
establishment of endothelial barrier
|
GO:0061028 |
16 |
0.421
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.418
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.418
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.416
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.415
|
Worm |
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.413
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.412
|
|
|
|
neuron migration
|
GO:0001764 |
11 |
0.412
|
Fly |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.411
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
1 |
0.410
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.409
|
Worm |
|
|
cognition
|
GO:0050890 |
43 |
0.407
|
Rat |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.403
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.400
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.398
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.395
|
|
|
|
regulation of rap protein signal transduction
|
GO:0032487 |
9 |
0.394
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.394
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.394
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.393
|
Mouse |
|
|
tor signaling
|
GO:0031929 |
39 |
0.389
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.389
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.389
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.387
|
Worm |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.386
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.384
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.382
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.381
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.379
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.378
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.376
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.371
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.371
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.370
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.365
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.364
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.364
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.364
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.364
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.360
|
Fly |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.358
|
Rat |
|
|
cell growth
|
GO:0016049 |
160 |
0.357
|
Mouse |
|
|
axon development
|
GO:0061564 |
34 |
0.357
|
Mouse Fly |
|
|
dna repair
|
GO:0006281 |
198 |
0.352
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.352
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.347
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.345
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.343
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.343
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.340
|
Fly |
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.340
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.337
|
|
|
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.333
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.329
|
Mouse |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.319
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.318
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.317
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.315
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.314
|
Mouse Fly |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.310
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.309
|
Mouse Fly |
|
|
nerve growth factor signaling pathway
|
GO:0038180 |
4 |
0.301
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.300
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.296
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.296
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.293
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.292
|
Worm |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.289
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.288
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.285
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.282
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.282
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.282
|
Rat |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.277
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.275
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.273
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.271
|
Rat |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.269
|
Worm |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.268
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.266
|
Human Rat |
|
|
digestive system development
|
GO:0055123 |
75 |
0.265
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.265
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.264
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
1 |
0.264
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.263
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.263
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.262
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.258
|
Mouse Fly |
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.257
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.257
|
Worm |
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.256
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.254
|
Worm |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.254
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.254
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.253
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.250
|
Worm Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.250
|
Fly |
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.248
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.246
|
Rat |
|
|
regulation of phagocytosis
|
GO:0050764 |
21 |
0.244
|
Worm |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.243
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.242
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.241
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.241
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.240
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.237
|
Worm |
|
|
protein maturation
|
GO:0051604 |
233 |
0.236
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.236
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.233
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.232
|
Mouse |
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.231
|
|
|
|
axon extension involved in axon guidance
|
GO:0048846 |
5 |
0.230
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.230
|
Worm |
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.230
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.229
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.229
|
Fly |
|
|
response to wounding
|
GO:0009611 |
168 |
0.227
|
|
|
|
reciprocal dna recombination
|
GO:0035825 |
4 |
0.227
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.226
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.223
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.223
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.222
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.222
|
Mouse |
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.220
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.219
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.219
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.217
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.216
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.215
|
Mouse |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.214
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.213
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.213
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.209
|
Mouse |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.207
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.206
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.204
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.204
|
Human Mouse Rat Fly |
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.203
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.203
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.203
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.200
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.199
|
|
|
|
neurotrophin signaling pathway
|
GO:0038179 |
8 |
0.199
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.199
|
Worm |
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.198
|
Mouse Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.197
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.195
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.193
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.191
|
Worm |
|
|
compound eye development
|
GO:0048749 |
1 |
0.191
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.191
|
Mouse |
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.191
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.191
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.190
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.190
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.188
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.187
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.185
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.182
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.182
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.181
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.181
|
Mouse |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.180
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.179
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.175
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.175
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.175
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.174
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.174
|
Mouse |
|
|
head development
|
GO:0060322 |
108 |
0.174
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.172
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.172
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.170
|
Mouse |
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.169
|
Mouse |
|
|
meiosis i
|
GO:0007127 |
4 |
0.169
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.168
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.166
|
Fly |
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031659 |
8 |
0.163
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.160
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.160
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.159
|
Mouse |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.159
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.157
|
Mouse Fly |
|
|
axon extension
|
GO:0048675 |
13 |
0.157
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.154
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.152
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.151
|
Fly |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.151
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.149
|
Mouse Worm |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.149
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.148
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.148
|
Fly |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.147
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.147
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.147
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.146
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.146
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.146
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.145
|
Mouse |
|
|
neural tube closure
|
GO:0001843 |
3 |
0.145
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.141
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.140
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.139
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.138
|
Mouse Fly |
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.138
|
Human Rat |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.137
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.136
|
Mouse |
|
|
histone acetylation
|
GO:0016573 |
93 |
0.134
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.132
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.132
|
Human Mouse |
|
|
secretion
|
GO:0046903 |
254 |
0.131
|
Mouse |
