Homo sapiens

24 known processes

SHANK2

SH3 and multiple ankyrin repeat domains 2

(Aliases: SHANK,ProSAP1,CORTBP1,CTTNBP1,SPANK-3,AUTS17)

SHANK2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amine metabolic process GO:0033238 11 0.332
inorganic cation transmembrane transport GO:0098662 194 0.247
post embryonic development GO:0009791 2 0.216
regulation of cellular amino acid metabolic process GO:0006521 6 0.215
epithelium development GO:0060429 227 0.198
regulation of cell differentiation GO:0045595 393 0.190
positive regulation of cellular component movement GO:0051272 181 0.183
cellular amino acid metabolic process GO:0006520 116 0.181
gtp catabolic process GO:0006184 237 0.180
regulation of cellular component movement GO:0051270 334 0.175
positive regulation of hydrolase activity GO:0051345 331 0.166
purine containing compound catabolic process GO:0072523 411 0.161
endodermal cell fate commitment GO:0001711 4 0.161
regulation of cellular ketone metabolic process GO:0010565 50 0.159
positive regulation of cellular amine metabolic process GO:0033240 7 0.158
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.153
small gtpase mediated signal transduction GO:0007264 78 0.153
system process GO:0003008 349 0.153
purine nucleotide catabolic process GO:0006195 405 0.151
nucleoside triphosphate catabolic process GO:0009143 394 0.149
ras protein signal transduction GO:0007265 73 0.145
nucleoside catabolic process GO:0009164 408 0.143
behavior GO:0007610 112 0.140
gtp metabolic process GO:0046039 239 0.135
cell morphogenesis GO:0000902 296 0.135
regulation of cell motility GO:2000145 299 0.134
epithelial cell differentiation GO:0030855 141 0.132
purine nucleoside triphosphate catabolic process GO:0009146 392 0.131
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.127
nucleoside triphosphate metabolic process GO:0009141 422 0.127
ribonucleoside triphosphate metabolic process GO:0009199 412 0.127
regulation of cell migration GO:0030334 289 0.126
metal ion homeostasis GO:0055065 169 0.125
cation transmembrane transport GO:0098655 238 0.125
ion transmembrane transport GO:0034220 338 0.124
locomotory behavior GO:0007626 1 0.124
nucleotide catabolic process GO:0009166 408 0.123
regulation of gtp catabolic process GO:0033124 180 0.123
positive regulation of cell motility GO:2000147 177 0.121
positive regulation of ras gtpase activity GO:0032320 117 0.121
rho protein signal transduction GO:0007266 26 0.116
nervous system development GO:0007399 293 0.115
Mouse Rat
positive regulation of locomotion GO:0040017 186 0.111
cell adhesion GO:0007155 325 0.109
actin filament based process GO:0030029 224 0.108
positive regulation of nucleotide catabolic process GO:0030813 185 0.107
signal transduction by phosphorylation GO:0023014 297 0.107
purine ribonucleotide catabolic process GO:0009154 404 0.107
ribonucleotide catabolic process GO:0009261 405 0.105
positive regulation of developmental process GO:0051094 314 0.104
nucleoside phosphate catabolic process GO:1901292 412 0.104
amine metabolic process GO:0009308 44 0.104
mapk cascade GO:0000165 288 0.104
regulation of hormone levels GO:0010817 125 0.103
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.103
purine ribonucleoside metabolic process GO:0046128 437 0.103
ribonucleoside triphosphate catabolic process GO:0009203 391 0.103
regulation of nucleotide catabolic process GO:0030811 205 0.102
positive regulation of cellular catabolic process GO:0031331 284 0.100
guanosine containing compound catabolic process GO:1901069 239 0.099
negative regulation of cell death GO:0060548 345 0.097
regulation of nucleoside metabolic process GO:0009118 209 0.096
cellular component morphogenesis GO:0032989 314 0.096
glycosyl compound catabolic process GO:1901658 413 0.096
cell projection morphogenesis GO:0048858 129 0.094
nerve development GO:0021675 4 0.093
regulation of purine nucleotide metabolic process GO:1900542 264 0.093
purine nucleoside triphosphate metabolic process GO:0009144 412 0.089
purine ribonucleoside catabolic process GO:0046130 398 0.087
regulation of purine nucleotide catabolic process GO:0033121 205 0.084
enzyme linked receptor protein signaling pathway GO:0007167 303 0.084
organophosphate catabolic process GO:0046434 430 0.084
cellular amine metabolic process GO:0044106 41 0.084
positive regulation of gtp catabolic process GO:0033126 166 0.083
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.080
memory GO:0007613 3 0.080
Mouse
cardiovascular system development GO:0072358 262 0.079
response to abiotic stimulus GO:0009628 336 0.079
transmembrane transport GO:0055085 399 0.078
second messenger mediated signaling GO:0019932 78 0.077
purine nucleoside catabolic process GO:0006152 398 0.077
positive regulation of phosphorylation GO:0042327 394 0.076
cell development GO:0048468 328 0.076
regulation of nucleotide metabolic process GO:0006140 269 0.076
positive regulation of catabolic process GO:0009896 310 0.075
regulation of ras protein signal transduction GO:0046578 155 0.074
anatomical structure formation involved in morphogenesis GO:0048646 284 0.074
positive regulation of nucleoside metabolic process GO:0045979 186 0.073
female gamete generation GO:0007292 2 0.071
positive regulation of gtpase activity GO:0043547 166 0.071
positive regulation of nucleotide metabolic process GO:0045981 230 0.070
positive regulation of cell migration GO:0030335 172 0.070
cell cell signaling GO:0007267 155 0.068
Mouse
organ morphogenesis GO:0009887 147 0.068
regulation of ras gtpase activity GO:0032318 128 0.066
negative regulation of apoptotic process GO:0043066 316 0.065
segmentation GO:0035282 4 0.064
morphogenesis of embryonic epithelium GO:0016331 4 0.064
ion homeostasis GO:0050801 230 0.062
regulation of proteolysis GO:0030162 293 0.062
neuromuscular junction development GO:0007528 3 0.062
cell projection organization GO:0030030 252 0.061
cellular ketone metabolic process GO:0042180 80 0.061
peptidyl tyrosine phosphorylation GO:0018108 170 0.060
regulation of anatomical structure morphogenesis GO:0022603 286 0.060
ribonucleoside catabolic process GO:0042454 406 0.060
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.059
cell fate determination GO:0001709 3 0.059
positive regulation of cellular component organization GO:0051130 376 0.059
regulation of cellular response to stress GO:0080135 244 0.058
negative regulation of phosphate metabolic process GO:0045936 267 0.058
negative regulation of developmental process GO:0051093 247 0.058
positive regulation of mapk cascade GO:0043410 190 0.056
regulation of actin filament based process GO:0032970 141 0.056
tube morphogenesis GO:0035239 95 0.056
regeneration GO:0031099 4 0.056
positive regulation of cell differentiation GO:0045597 211 0.056
tissue morphogenesis GO:0048729 96 0.055
forebrain generation of neurons GO:0021872 3 0.055
single organism cell adhesion GO:0098602 179 0.055
cellular ion homeostasis GO:0006873 168 0.054
protein catabolic process GO:0030163 325 0.054
regulation of cellular component biogenesis GO:0044087 281 0.053
regulation of gtpase activity GO:0043087 180 0.053
inorganic ion transmembrane transport GO:0098660 231 0.053
cytoplasmic transport GO:0016482 379 0.052
regulation of locomotion GO:0040012 329 0.052
cellular macromolecule catabolic process GO:0044265 380 0.051
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.051
cellular response to growth factor stimulus GO:0071363 197 0.051
divalent inorganic cation homeostasis GO:0072507 136 0.051
positive regulation of protein phosphorylation GO:0001934 313 0.050
biological adhesion GO:0022610 331 0.050
neurogenesis GO:0022008 169 0.049
oogenesis GO:0048477 2 0.048
metal ion transport GO:0030001 272 0.048
regulation of mapk cascade GO:0043408 262 0.048
cranial nerve development GO:0021545 4 0.048
intracellular protein transport GO:0006886 270 0.047
tube development GO:0035295 125 0.047
cellular response to oxygen containing compound GO:1901701 276 0.047
regulation of small gtpase mediated signal transduction GO:0051056 156 0.046
regulation of mitotic cell cycle GO:0007346 189 0.046
mitotic cell cycle process GO:1903047 286 0.046
digestive system development GO:0055123 75 0.045
secretion GO:0046903 254 0.045
peripheral nervous system development GO:0007422 2 0.045
cation transport GO:0006812 331 0.045
chemical homeostasis GO:0048878 306 0.044
microtubule based process GO:0007017 210 0.044
single organismal cell cell adhesion GO:0016337 148 0.044
neuron projection development GO:0031175 106 0.044
guanosine containing compound metabolic process GO:1901068 244 0.043
cellular response to endogenous stimulus GO:0071495 336 0.043
regulation of growth GO:0040008 165 0.043
muscle structure development GO:0061061 98 0.042
compound eye development GO:0048749 1 0.042
negative regulation of cell cycle GO:0045786 193 0.042
cation homeostasis GO:0055080 189 0.042
forebrain neuron differentiation GO:0021879 3 0.042
monovalent inorganic cation transport GO:0015672 128 0.042
actin cytoskeleton organization GO:0030036 207 0.042
regulation of transferase activity GO:0051338 355 0.041
negative regulation of transport GO:0051051 176 0.040
regulation of intracellular transport GO:0032386 195 0.040
mitotic cell cycle GO:0000278 326 0.040
regulation of cell cycle GO:0051726 393 0.040
growth GO:0040007 202 0.040
regulation of secretion by cell GO:1903530 177 0.040
calcium ion homeostasis GO:0055074 122 0.039
nitrogen compound transport GO:0071705 191 0.039
positive regulation of proteolysis GO:0045862 142 0.039
regulation of cell development GO:0060284 161 0.039
circadian behavior GO:0048512 2 0.038
regulation of cell growth GO:0001558 135 0.038
endodermal cell fate specification GO:0001714 4 0.038
negative regulation of programmed cell death GO:0043069 321 0.038
immune system development GO:0002520 195 0.038
positive regulation of protein kinase activity GO:0045860 190 0.038
regulation of ion transport GO:0043269 189 0.038
small molecule biosynthetic process GO:0044283 157 0.038
response to growth factor GO:0070848 205 0.037
regulation of protein serine threonine kinase activity GO:0071900 179 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.037
cell substrate adhesion GO:0031589 132 0.037
cell part morphogenesis GO:0032990 137 0.036
circulatory system development GO:0072359 262 0.036
peptidyl tyrosine modification GO:0018212 170 0.036
organic hydroxy compound metabolic process GO:1901615 147 0.036
embryonic epithelial tube formation GO:0001838 4 0.036
protein autophosphorylation GO:0046777 123 0.036
blood vessel development GO:0001568 172 0.036
vasculature development GO:0001944 181 0.035
positive regulation of intracellular transport GO:0032388 104 0.035
regulation of epithelial cell migration GO:0010632 93 0.034
response to lipid GO:0033993 206 0.034
regulation of body fluid levels GO:0050878 99 0.034
regulation of protein catabolic process GO:0042176 155 0.033
negative regulation of phosphorus metabolic process GO:0010563 267 0.033
wnt signaling pathway GO:0016055 156 0.033
oocyte differentiation GO:0009994 2 0.033
ameboidal type cell migration GO:0001667 135 0.033
sequestering of metal ion GO:0051238 24 0.033
neural crest cell development GO:0014032 3 0.033
digestive tract development GO:0048565 75 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.032
extrinsic apoptotic signaling pathway GO:0097191 119 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.032
regulation of intracellular protein transport GO:0033157 123 0.031
response to oxygen containing compound GO:1901700 369 0.031
cellular metal ion homeostasis GO:0006875 146 0.031
blood vessel morphogenesis GO:0048514 162 0.031
cellular response to cytokine stimulus GO:0071345 181 0.031
cellular macromolecular complex assembly GO:0034622 324 0.031
regulation of cytoplasmic transport GO:1903649 149 0.031
response to cytokine GO:0034097 232 0.031
regulation of peptidase activity GO:0052547 180 0.031
regulation of protein transport GO:0051223 213 0.031
apoptotic signaling pathway GO:0097190 268 0.030
cell projection assembly GO:0030031 126 0.030
positive regulation of transport GO:0051050 336 0.030
positive regulation of programmed cell death GO:0043068 249 0.030
positive regulation of cell death GO:0010942 263 0.030
synaptic transmission GO:0007268 61 0.030
Mouse
embryo development GO:0009790 123 0.030
regulation of cell adhesion GO:0030155 166 0.030
single organism reproductive process GO:0044702 98 0.029
epithelial cell proliferation GO:0050673 128 0.029
stress activated protein kinase signaling cascade GO:0031098 94 0.029
reactive oxygen species metabolic process GO:0072593 75 0.029
blastoderm segmentation GO:0007350 2 0.029
epithelial cell migration GO:0010631 119 0.029
regulation of membrane potential GO:0042391 95 0.029
motor neuron axon guidance GO:0008045 2 0.029
immune response GO:0006955 307 0.028
regulation of epithelial cell proliferation GO:0050678 113 0.028
regulation of cytoskeleton organization GO:0051493 177 0.028
cellular homeostasis GO:0019725 196 0.028
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.028
regulation of kinase activity GO:0043549 314 0.027
stem cell differentiation GO:0048863 93 0.027
wound healing GO:0042060 115 0.027
positive regulation of protein transport GO:0051222 135 0.027
membrane organization GO:0061024 292 0.027
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.027
generation of neurons GO:0048699 152 0.027
photoreceptor cell differentiation GO:0046530 2 0.027
positive regulation of cytoplasmic transport GO:1903651 82 0.027
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.027
regulation of jnk cascade GO:0046328 73 0.027
male genitalia development GO:0030539 1 0.027
microtubule cytoskeleton organization GO:0000226 176 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
regulation of cell cycle phase transition GO:1901987 126 0.027
lipid metabolic process GO:0006629 381 0.027
regulation of transmembrane transport GO:0034762 139 0.027
sequestering of calcium ion GO:0051208 17 0.026
regulation of rho gtpase activity GO:0032319 66 0.026
hematopoietic or lymphoid organ development GO:0048534 186 0.026
multicellular organismal aging GO:0010259 3 0.026
vesicle mediated transport GO:0016192 371 0.026
organophosphate biosynthetic process GO:0090407 163 0.026
actin filament organization GO:0007015 128 0.026
cell cycle phase transition GO:0044770 173 0.026
regulation of cell morphogenesis GO:0022604 153 0.026
tissue regeneration GO:0042246 3 0.026
negative regulation of cell differentiation GO:0045596 171 0.026
phosphatidylinositol mediated signaling GO:0048015 55 0.026
multicellular organismal homeostasis GO:0048871 67 0.026
oocyte development GO:0048599 1 0.026
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
associative learning GO:0008306 1 0.025
divalent metal ion transport GO:0070838 152 0.025
cell morphogenesis involved in differentiation GO:0000904 144 0.025
negative regulation of hydrolase activity GO:0051346 182 0.025
regulation of nervous system development GO:0051960 88 0.025
regulation of protein localization GO:0032880 296 0.025
cellular cation homeostasis GO:0030003 163 0.025
positive regulation of cellular component biogenesis GO:0044089 158 0.025
mesenchymal cell development GO:0014031 50 0.025
cellular lipid metabolic process GO:0044255 303 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
response to hormone GO:0009725 175 0.024
negative regulation of cell proliferation GO:0008285 228 0.024
cellular response to lipid GO:0071396 127 0.024
morphogenesis of an epithelium GO:0002009 60 0.024
angiogenesis GO:0001525 147 0.024
endodermal cell differentiation GO:0035987 31 0.024
response to wounding GO:0009611 168 0.024
jnk cascade GO:0007254 80 0.024
response to nitrogen compound GO:1901698 184 0.024
regulation of apoptotic signaling pathway GO:2001233 175 0.024
regulation of wnt signaling pathway GO:0030111 123 0.024
secretion by cell GO:0032940 226 0.024
positive regulation of kinase activity GO:0033674 204 0.023
taxis GO:0042330 157 0.023
reproductive process GO:0022414 106 0.023
organic hydroxy compound biosynthetic process GO:1901617 71 0.023
central nervous system development GO:0007417 123 0.023
Rat
organelle assembly GO:0070925 176 0.023
skin development GO:0043588 76 0.023
proteasomal protein catabolic process GO:0010498 176 0.023
ossification GO:0001503 121 0.023
phospholipid metabolic process GO:0006644 99 0.023
glial cell migration GO:0008347 4 0.023
response to oxidative stress GO:0006979 121 0.023
positive regulation of map kinase activity GO:0043406 80 0.023
protein ubiquitination GO:0016567 314 0.023
neuroblast proliferation GO:0007405 4 0.022
response to organic cyclic compound GO:0014070 204 0.022
endomembrane system organization GO:0010256 196 0.022
neural crest cell migration GO:0001755 2 0.022
negative regulation of mitotic cell cycle GO:0045930 102 0.022
chordate embryonic development GO:0043009 34 0.022
activation of protein kinase activity GO:0032147 90 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.022
neurotransmitter secretion GO:0007269 4 0.022
lipid biosynthetic process GO:0008610 177 0.022
positive regulation of secretion by cell GO:1903532 108 0.022
protein localization to organelle GO:0033365 280 0.022
regulation of neuron differentiation GO:0045664 70 0.022
single organism cellular localization GO:1902580 332 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
cellular potassium ion transport GO:0071804 60 0.022
regulation of cell cycle process GO:0010564 266 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
alcohol metabolic process GO:0006066 114 0.021
cell type specific apoptotic process GO:0097285 125 0.021
neuron fate commitment GO:0048663 2 0.021
dephosphorylation GO:0016311 209 0.021
erk1 and erk2 cascade GO:0070371 104 0.021
circulatory system process GO:0003013 113 0.021
regulation of protein kinase activity GO:0045859 289 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.021
single organism membrane organization GO:0044802 268 0.021
protein processing GO:0016485 226 0.021
spermatid differentiation GO:0048515 4 0.021
mesenchyme development GO:0060485 59 0.021
regulation of stress activated mapk cascade GO:0032872 84 0.021
epithelium migration GO:0090132 119 0.021
negative regulation of cell migration GO:0030336 102 0.021
positive regulation of apoptotic process GO:0043065 246 0.021
glycerolipid metabolic process GO:0046486 107 0.021
protein localization to nucleus GO:0034504 136 0.021
renal system development GO:0072001 63 0.021
endothelial cell migration GO:0043542 86 0.020
regulation of neurogenesis GO:0050767 82 0.020
determination of adult lifespan GO:0008340 2 0.020
neuron development GO:0048666 113 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
maintenance of location GO:0051235 112 0.020
regulation of actin cytoskeleton organization GO:0032956 116 0.020
anatomical structure homeostasis GO:0060249 100 0.020
chromatin modification GO:0016568 298 0.020
neuron differentiation GO:0030182 138 0.020
canonical wnt signaling pathway GO:0060070 116 0.020
cytosolic calcium ion homeostasis GO:0051480 89 0.020
actin filament based movement GO:0030048 17 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.020
regulation of cell projection organization GO:0031344 107 0.019
leukocyte activation GO:0045321 164 0.019
negative regulation of wnt signaling pathway GO:0030178 69 0.019
digestive tract morphogenesis GO:0048546 56 0.019
neural tube formation GO:0001841 3 0.019
morphogenesis of a polarized epithelium GO:0001738 3 0.019
innate immune response GO:0045087 178 0.019
stem cell development GO:0048864 69 0.019
cyclic nucleotide metabolic process GO:0009187 82 0.019
regulation of erk1 and erk2 cascade GO:0070372 99 0.019
endocrine system development GO:0035270 26 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
sensory organ development GO:0007423 52 0.019
divalent inorganic cation transport GO:0072511 158 0.019
cell junction organization GO:0034330 79 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.019
regulation of secretion GO:0051046 194 0.019
regulation of mitotic cell cycle phase transition GO:1901990 118 0.019
regulation of behavior GO:0050795 82 0.019
cell cell junction organization GO:0045216 69 0.019
positive regulation of cell development GO:0010720 92 0.018
mesodermal cell fate commitment GO:0001710 2 0.018
negative regulation of protein metabolic process GO:0051248 391 0.018
hemopoiesis GO:0030097 180 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
cilium morphogenesis GO:0060271 75 0.018
positive regulation of cell cycle GO:0045787 140 0.018
cell growth GO:0016049 160 0.018
cell matrix adhesion GO:0007160 85 0.018
defense response GO:0006952 315 0.018
regulation of ion transmembrane transporter activity GO:0032412 72 0.018
cellular divalent inorganic cation homeostasis GO:0072503 128 0.018
hormone transport GO:0009914 68 0.018
cellular protein complex assembly GO:0043623 188 0.018
limb bud formation GO:0060174 1 0.018
negative regulation of cell growth GO:0030308 83 0.018
cell activation GO:0001775 213 0.018
sex determination GO:0007530 3 0.018
inner ear morphogenesis GO:0042472 4 0.018
tissue migration GO:0090130 119 0.018
positive regulation of neurogenesis GO:0050769 49 0.018
salivary gland morphogenesis GO:0007435 4 0.018
regulation of endopeptidase activity GO:0052548 170 0.018
mitotic cell cycle phase transition GO:0044772 162 0.018
regulation of dephosphorylation GO:0035303 96 0.018
positive regulation of dna metabolic process GO:0051054 73 0.018
nucleocytoplasmic transport GO:0006913 176 0.017
negative regulation of growth GO:0045926 97 0.017
response to transforming growth factor beta GO:0071559 94 0.017
negative regulation of apoptotic signaling pathway GO:2001234 97 0.017
epidermis development GO:0008544 59 0.017
regulation of ion homeostasis GO:2000021 73 0.017
regulation of proteasomal protein catabolic process GO:0061136 87 0.017
muscle cell fate commitment GO:0042693 4 0.017
gastrulation GO:0007369 51 0.017
neurological system process GO:0050877 163 0.017
positive regulation of cytokine production GO:0001819 167 0.017
regulation of neuron projection development GO:0010975 57 0.017
adult locomotory behavior GO:0008344 1 0.017
peptidyl serine modification GO:0018209 106 0.017
endoderm development GO:0007492 33 0.017
eye photoreceptor cell differentiation GO:0001754 2 0.017
gland development GO:0048732 48 0.017
glycerolipid biosynthetic process GO:0045017 51 0.017
positive regulation of endopeptidase activity GO:0010950 84 0.017
regulation of vesicle mediated transport GO:0060627 130 0.017
soft palate development GO:0060023 3 0.017
negative regulation of locomotion GO:0040013 118 0.017
regulation of cysteine type endopeptidase activity GO:2000116 127 0.017
action potential GO:0001508 34 0.017
endoderm formation GO:0001706 33 0.016
regulation of endothelial cell migration GO:0010594 67 0.016
regulation of map kinase activity GO:0043405 108 0.016
negative regulation of protein modification process GO:0031400 200 0.016
positive regulation of transferase activity GO:0051347 227 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.016
eye development GO:0001654 42 0.016
response to acid chemical GO:0001101 66 0.016
carbohydrate metabolic process GO:0005975 207 0.016
regulation of phosphatase activity GO:0010921 81 0.016
response to biotic stimulus GO:0009607 276 0.016
protein import GO:0017038 130 0.016
reproductive system development GO:0061458 56 0.016
peptidyl serine phosphorylation GO:0018105 101 0.016
osteoblast differentiation GO:0001649 92 0.016
cellular protein catabolic process GO:0044257 261 0.016
negative regulation of cell cycle phase transition GO:1901988 89 0.016
plasma membrane organization GO:0007009 115 0.016
negative regulation of cell motility GO:2000146 104 0.016
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.016
regulation of dna metabolic process GO:0051052 153 0.016
regulation of calcium ion transport into cytosol GO:0010522 33 0.016
cellular response to nitrogen compound GO:1901699 144 0.016
tissue homeostasis GO:0001894 63 0.016
hormone metabolic process GO:0042445 61 0.016
regulation of binding GO:0051098 111 0.016
regulation of male gonad development GO:2000018 4 0.016
regulation of anatomical structure size GO:0090066 101 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
regulation of cardiac muscle cell proliferation GO:0060043 4 0.016
head development GO:0060322 108 0.016
Rat
signal release GO:0023061 70 0.015
cellular calcium ion homeostasis GO:0006874 117 0.015
positive regulation of epithelial cell proliferation GO:0050679 65 0.015
cell cycle g1 s phase transition GO:0044843 80 0.015
regulation of cytokine production GO:0001817 232 0.015
epithelial cell development GO:0002064 34 0.015
response to other organism GO:0051707 261 0.015
mitochondrion organization GO:0007005 156 0.015
reactive nitrogen species metabolic process GO:2001057 3 0.015
negative regulation of gliogenesis GO:0014014 3 0.015
negative regulation of cell adhesion GO:0007162 64 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.015
kidney development GO:0001822 53 0.015
hindbrain development GO:0030902 3 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
g1 s transition of mitotic cell cycle GO:0000082 78 0.015
regulation of camp biosynthetic process GO:0030817 45 0.015
pattern specification process GO:0007389 43 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
positive regulation of rho gtpase activity GO:0032321 56 0.015
dendritic spine morphogenesis GO:0060997 3 0.015
developmental process involved in reproduction GO:0003006 66 0.015

SHANK2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.036
cancer DOID:162 167 0.028
organ system cancer DOID:0050686 164 0.024
sensory system disease DOID:0050155 203 0.022
nervous system disease DOID:863 431 0.022
musculoskeletal system disease DOID:17 223 0.018
connective tissue disease DOID:65 109 0.018
central nervous system disease DOID:331 186 0.017
neurodegenerative disease DOID:1289 102 0.017
disease of metabolism DOID:0014667 295 0.015
bone disease DOID:0080001 88 0.015