Homo sapiens

60 known processes

UGT1A1

UDP glucuronosyltransferase 1 family, polypeptide A1

(Aliases: HUG-BR1,UGT1,UGT1A,BILIQTL1,UDPGT,UDPGT 1-1,GNT1)

UGT1A1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
uronic acid metabolic process GO:0006063 16 1.000
glucuronate metabolic process GO:0019585 16 1.000
cellular glucuronidation GO:0052695 16 1.000
flavonoid glucuronidation GO:0052696 5 1.000
xenobiotic metabolic process GO:0006805 28 0.971
cellular response to xenobiotic stimulus GO:0071466 29 0.965
response to xenobiotic stimulus GO:0009410 30 0.946
monocarboxylic acid metabolic process GO:0032787 185 0.933
flavonoid metabolic process GO:0009812 8 0.925
xenobiotic glucuronidation GO:0052697 5 0.904
estrogen catabolic process GO:0006711 1 0.876
carbohydrate metabolic process GO:0005975 207 0.842
single organism carbohydrate metabolic process GO:0044723 193 0.823
monosaccharide metabolic process GO:0005996 74 0.818
regulation of cellular glucuronidation GO:2001029 5 0.645
cellular lipid metabolic process GO:0044255 303 0.452
cellular response to hydroxyisoflavone GO:0071413 1 0.319
lipid metabolic process GO:0006629 381 0.274
drug metabolic process GO:0017144 19 0.247
sensory perception of smell GO:0007608 2 0.178
regulation of lipid metabolic process GO:0019216 96 0.161
regulation of hormone levels GO:0010817 125 0.130
hormone metabolic process GO:0042445 61 0.120
oxidation reduction process GO:0055114 396 0.097
cellular ketone metabolic process GO:0042180 80 0.070
regulation of carbohydrate metabolic process GO:0006109 54 0.070
cellular amino acid metabolic process GO:0006520 116 0.065
regulation of transferase activity GO:0051338 355 0.065
cellular amine metabolic process GO:0044106 41 0.057
chemical homeostasis GO:0048878 306 0.056
response to organic cyclic compound GO:0014070 204 0.050
protein processing GO:0016485 226 0.046
anion transport GO:0006820 161 0.045
epithelium development GO:0060429 227 0.042
negative regulation of transferase activity GO:0051348 124 0.042
post embryonic development GO:0009791 2 0.042
organic anion transport GO:0015711 103 0.039
regulation of cellular ketone metabolic process GO:0010565 50 0.039
epoxygenase p450 pathway GO:0019373 3 0.037
organic hydroxy compound metabolic process GO:1901615 147 0.035
cellular response to endogenous stimulus GO:0071495 336 0.034
determination of adult lifespan GO:0008340 2 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
negative regulation of protein metabolic process GO:0051248 391 0.031
negative regulation of cellular carbohydrate metabolic process GO:0010677 14 0.031
ion homeostasis GO:0050801 230 0.031
system process GO:0003008 349 0.030
response to steroid hormone GO:0048545 80 0.030
female gamete generation GO:0007292 2 0.029
cellular response to lipid GO:0071396 127 0.029
carboxylic acid biosynthetic process GO:0046394 97 0.029
multicellular organismal aging GO:0010259 3 0.028
cellular response to oxygen containing compound GO:1901701 276 0.026
amine metabolic process GO:0009308 44 0.026
cytoplasmic transport GO:0016482 379 0.026
fatty acid derivative metabolic process GO:1901568 35 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
regulation of cellular amine metabolic process GO:0033238 11 0.024
alcohol metabolic process GO:0006066 114 0.024
cellular response to hormone stimulus GO:0032870 125 0.024
defense response GO:0006952 315 0.023
immune response GO:0006955 307 0.023
nitrogen compound transport GO:0071705 191 0.022
response to phenylpropanoid GO:0080184 1 0.022
sulfur compound metabolic process GO:0006790 101 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
protein maturation GO:0051604 233 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
regulation of proteolysis GO:0030162 293 0.021
cellular amide metabolic process GO:0043603 69 0.021
regulation of cell cycle GO:0051726 393 0.020
demethylation GO:0070988 37 0.020
dephosphorylation GO:0016311 209 0.020
9 cis retinoic acid metabolic process GO:0042905 1 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
epithelial cell differentiation GO:0030855 141 0.020
fatty acid metabolic process GO:0006631 115 0.020
multi organism cellular process GO:0044764 156 0.020
positive regulation of apoptotic process GO:0043065 246 0.019
response to other organism GO:0051707 261 0.019
blood circulation GO:0008015 113 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
regulation of cell cycle process GO:0010564 266 0.019
monocarboxylic acid biosynthetic process GO:0072330 67 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.018
regulation of protein processing GO:0070613 150 0.018
oogenesis GO:0048477 2 0.018
purine containing compound catabolic process GO:0072523 411 0.018
circulatory system process GO:0003013 113 0.018
ras protein signal transduction GO:0007265 73 0.018
negative regulation of cell proliferation GO:0008285 228 0.018
unsaturated fatty acid metabolic process GO:0033559 37 0.018
segmentation GO:0035282 4 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
protein catabolic process GO:0030163 325 0.017
regulation of kinase activity GO:0043549 314 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
interspecies interaction between organisms GO:0044419 156 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
primary alcohol metabolic process GO:0034308 17 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
neuromuscular junction development GO:0007528 3 0.017
regulation of response to external stimulus GO:0032101 222 0.017
nucleotide catabolic process GO:0009166 408 0.017
regeneration GO:0031099 4 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
regulation of cellular component movement GO:0051270 334 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
epithelial cell proliferation GO:0050673 128 0.016
mitotic cell cycle GO:0000278 326 0.016
rho protein signal transduction GO:0007266 26 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
cellular component morphogenesis GO:0032989 314 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
cellular protein catabolic process GO:0044257 261 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
metal ion homeostasis GO:0055065 169 0.016
apoptotic signaling pathway GO:0097190 268 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
cell morphogenesis GO:0000902 296 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
innate immune response GO:0045087 178 0.015
viral process GO:0016032 146 0.015
cellular carbohydrate metabolic process GO:0044262 84 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
vitamin e metabolic process GO:0042360 1 0.015
actin filament based process GO:0030029 224 0.015
mapk cascade GO:0000165 288 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
regulation of multi organism process GO:0043900 157 0.015
positive regulation of catabolic process GO:0009896 310 0.015
chromatin organization GO:0006325 351 0.015
positive regulation of transport GO:0051050 336 0.015
transmembrane transport GO:0055085 399 0.015
single organism membrane organization GO:0044802 268 0.015
viral life cycle GO:0019058 132 0.015
mitotic cell cycle process GO:1903047 286 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
single organism cellular localization GO:1902580 332 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
immune effector process GO:0002252 159 0.015
negative regulation of protein modification process GO:0031400 200 0.015
peripheral nervous system development GO:0007422 2 0.015
secretion GO:0046903 254 0.015
regulation of locomotion GO:0040012 329 0.015
positive regulation of hydrolase activity GO:0051345 331 0.014
cellular lipid catabolic process GO:0044242 65 0.014
response to oxygen containing compound GO:1901700 369 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
cellular modified amino acid metabolic process GO:0006575 64 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
naphthalene containing compound metabolic process GO:0090420 1 0.014
icosanoid catabolic process GO:1901523 2 0.014
organophosphate catabolic process GO:0046434 430 0.014
cation homeostasis GO:0055080 189 0.014
regulation of protein localization GO:0032880 296 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
negative regulation of cell death GO:0060548 345 0.014
ion transmembrane transport GO:0034220 338 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
regulation of protein maturation GO:1903317 150 0.014
response to external biotic stimulus GO:0043207 261 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
negative regulation of proteolysis GO:0045861 132 0.014
response to abiotic stimulus GO:0009628 336 0.014
regulation of cellular response to stress GO:0080135 244 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.014
positive regulation of immune system process GO:0002684 283 0.014
organic acid transport GO:0015849 65 0.014
nucleoside catabolic process GO:0009164 408 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
protein targeting GO:0006605 187 0.013
intracellular protein transport GO:0006886 270 0.013
response to biotic stimulus GO:0009607 276 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
regulation of immune response GO:0050776 201 0.013
intracellular receptor signaling pathway GO:0030522 104 0.013
defense response to other organism GO:0098542 129 0.013
nitrogen cycle metabolic process GO:0071941 3 0.013
response to virus GO:0009615 126 0.013
cellular cation homeostasis GO:0030003 163 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
regulation of protein kinase activity GO:0045859 289 0.013
anterior posterior axis specification GO:0009948 2 0.013
positive regulation of plasminogen activation GO:0010756 3 0.013
oocyte development GO:0048599 1 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
lipid biosynthetic process GO:0008610 177 0.013
blastoderm segmentation GO:0007350 2 0.013
urea metabolic process GO:0019627 3 0.013
negative regulation of protein processing GO:0010955 142 0.013
regulation of peptidase activity GO:0052547 180 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
cell division GO:0051301 168 0.013
small molecule biosynthetic process GO:0044283 157 0.013
purine nucleoside triphosphate catabolic process GO:0009146 392 0.013
maintenance of location GO:0051235 112 0.013
negative regulation of protein maturation GO:1903318 142 0.013
positive regulation of organelle organization GO:0010638 195 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
regulation of intracellular transport GO:0032386 195 0.013
protein localization to organelle GO:0033365 280 0.012
spermatid differentiation GO:0048515 4 0.012
response to inorganic substance GO:0010035 127 0.012
biological adhesion GO:0022610 331 0.012
cell growth GO:0016049 160 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
regulation of viral process GO:0050792 103 0.012
response to fungus GO:0009620 4 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
endomembrane system organization GO:0010256 196 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
histone modification GO:0016570 251 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
coumarin metabolic process GO:0009804 2 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
protein ubiquitination GO:0016567 314 0.012
positive regulation of cell death GO:0010942 263 0.012
positive regulation of locomotion GO:0040017 186 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
covalent chromatin modification GO:0016569 254 0.012
membrane organization GO:0061024 292 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
neurological system process GO:0050877 163 0.012
nuclear transport GO:0051169 179 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
g protein coupled receptor signaling pathway GO:0007186 207 0.012
regulation of cell differentiation GO:0045595 393 0.012
carboxylic acid transport GO:0046942 63 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
drug catabolic process GO:0042737 10 0.012
response to organonitrogen compound GO:0010243 156 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
cellular ion homeostasis GO:0006873 168 0.011
positive regulation of cell cycle process GO:0090068 106 0.011
protein oligomerization GO:0051259 173 0.011
negative regulation of cellular organohalogen metabolic process GO:0090349 1 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
regulation of mapk cascade GO:0043408 262 0.011
tripartite regional subdivision GO:0007351 2 0.011
locomotory behavior GO:0007626 1 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
response to bacterium GO:0009617 144 0.011
actin cytoskeleton organization GO:0030036 207 0.011
compound eye development GO:0048749 1 0.011
regulation of protein catabolic process GO:0042176 155 0.011
chromatin modification GO:0016568 298 0.011
response to nutrient levels GO:0031667 81 0.011
protein autophosphorylation GO:0046777 123 0.011
regulation of cell division GO:0051302 116 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
lipid transport GO:0006869 90 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
hindbrain development GO:0030902 3 0.011
positive regulation of ion transport GO:0043270 87 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
cytokine production GO:0001816 247 0.011
cellular chemical homeostasis GO:0055082 180 0.011
cell adhesion GO:0007155 325 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
oocyte differentiation GO:0009994 2 0.011
cellular homeostasis GO:0019725 196 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
negative regulation of organelle organization GO:0010639 126 0.011
tissue regeneration GO:0042246 3 0.011
spermatid development GO:0007286 4 0.011
cellular protein complex assembly GO:0043623 188 0.011
vesicle mediated transport GO:0016192 371 0.011
cofactor metabolic process GO:0051186 87 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
organic acid biosynthetic process GO:0016053 97 0.011
response to genistein GO:0033595 1 0.011
response to lipid GO:0033993 206 0.010
embryonic epithelial tube formation GO:0001838 4 0.010
retinoid metabolic process GO:0001523 18 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.010
tissue migration GO:0090130 119 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
growth GO:0040007 202 0.010
organic hydroxy compound biosynthetic process GO:1901617 71 0.010
developmental programmed cell death GO:0010623 3 0.010
glycosylation GO:0070085 71 0.010
macromolecule glycosylation GO:0043413 63 0.010
protein homooligomerization GO:0051260 100 0.010
regulation of protein transport GO:0051223 213 0.010
anterior posterior axis specification embryo GO:0008595 2 0.010
negative regulation of endopeptidase activity GO:0010951 84 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
cell projection organization GO:0030030 252 0.010
regulation of epithelial cell proliferation GO:0050678 113 0.010
nervous system development GO:0007399 293 0.010
negative regulation of developmental process GO:0051093 247 0.010
regulation of actin filament based process GO:0032970 141 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
regulation of dna metabolic process GO:0051052 153 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010

UGT1A1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.029
inherited metabolic disorder DOID:655 242 0.029
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020
musculoskeletal system disease DOID:17 223 0.018
disease of cellular proliferation DOID:14566 174 0.016
cancer DOID:162 167 0.015
organ system cancer DOID:0050686 164 0.015
sensory system disease DOID:0050155 203 0.011
neurodegenerative disease DOID:1289 102 0.011