Homo sapiens

269 known processes

GDNF

glial cell derived neurotrophic factor

(Aliases: HFB1-GDNF,ATF1,HSCR3,ATF2)

GDNF biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 80 0.326
regulation of cellular ketone metabolic process GO:0010565 50 0.309
regulation of cellular amine metabolic process GO:0033238 11 0.247
cellular amino acid metabolic process GO:0006520 116 0.245
circulatory system development GO:0072359 262 0.244
positive regulation of protein phosphorylation GO:0001934 313 0.233
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.227
regulation of cell differentiation GO:0045595 393 0.223
Mouse
cellular amine metabolic process GO:0044106 41 0.221
positive regulation of cellular amine metabolic process GO:0033240 7 0.219
positive regulation of cellular component organization GO:0051130 376 0.214
Mouse
positive regulation of cell proliferation GO:0008284 301 0.213
positive regulation of phosphorylation GO:0042327 394 0.209
negative regulation of multicellular organismal process GO:0051241 317 0.207
cellular response to endogenous stimulus GO:0071495 336 0.204
Rat
amine metabolic process GO:0009308 44 0.199
regulation of cellular amino acid metabolic process GO:0006521 6 0.188
system process GO:0003008 349 0.181
Mouse
positive regulation of developmental process GO:0051094 314 0.173
negative regulation of developmental process GO:0051093 247 0.171
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.169
cell development GO:0048468 328 0.168
regulation of hormone levels GO:0010817 125 0.159
positive regulation of aldosterone metabolic process GO:0032346 2 0.154
enzyme linked receptor protein signaling pathway GO:0007167 303 0.152
regulation of anatomical structure morphogenesis GO:0022603 286 0.152
nervous system development GO:0007399 293 0.151
epithelium development GO:0060429 227 0.147
organ formation GO:0048645 3 0.143
Mouse
cardiovascular system development GO:0072358 262 0.143
positive regulation of mapk cascade GO:0043410 190 0.141
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.139
mesenchyme development GO:0060485 59 0.134
regulation of cellular component movement GO:0051270 334 0.129
anatomical structure formation involved in morphogenesis GO:0048646 284 0.127
negative regulation of cell death GO:0060548 345 0.126
specification of organ identity GO:0010092 3 0.125
Mouse
regulation of cell motility GO:2000145 299 0.124
regulation of cell migration GO:0030334 289 0.121
regulation of locomotion GO:0040012 329 0.120
regulation of transferase activity GO:0051338 355 0.119
regulation of dermatome development GO:0061183 3 0.117
signal transduction by phosphorylation GO:0023014 297 0.117
positive regulation of cell differentiation GO:0045597 211 0.117
Mouse
extraocular skeletal muscle development GO:0002074 1 0.116
regulation of kinase activity GO:0043549 314 0.114
organ morphogenesis GO:0009887 147 0.113
dermatome development GO:0061054 3 0.110
regulation of protein kinase activity GO:0045859 289 0.107
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.107
negative regulation of protein metabolic process GO:0051248 391 0.105
forelimb morphogenesis GO:0035136 4 0.103
regulation of protein localization GO:0032880 296 0.102
cell cell signaling GO:0007267 155 0.102
negative regulation of cell differentiation GO:0045596 171 0.101
cell adhesion GO:0007155 325 0.101
response to growth factor GO:0070848 205 0.100
regulation of mapk cascade GO:0043408 262 0.100
neuron fate commitment GO:0048663 2 0.099
negative regulation of cell proliferation GO:0008285 228 0.098
urogenital system development GO:0001655 65 0.097
negative regulation of apoptotic process GO:0043066 316 0.097
mapk cascade GO:0000165 288 0.096
regulation of cell cycle GO:0051726 393 0.095
tube development GO:0035295 125 0.095
chemical homeostasis GO:0048878 306 0.094
positive regulation of transferase activity GO:0051347 227 0.093
tube morphogenesis GO:0035239 95 0.092
positive regulation of epithelial cell proliferation GO:0050679 65 0.092
lipid metabolic process GO:0006629 381 0.091
mesenchymal cell differentiation GO:0048762 52 0.090
cell morphogenesis GO:0000902 296 0.089
Mouse Rat
post embryonic development GO:0009791 2 0.089
negative regulation of testosterone biosynthetic process GO:2000225 1 0.089
response to abiotic stimulus GO:0009628 336 0.088
positive regulation of locomotion GO:0040017 186 0.087
negative regulation of programmed cell death GO:0043069 321 0.085
positive regulation of protein kinase activity GO:0045860 190 0.084
immune system development GO:0002520 195 0.084
hematopoietic or lymphoid organ development GO:0048534 186 0.084
positive regulation of catabolic process GO:0009896 310 0.083
stem cell differentiation GO:0048863 93 0.083
spinal cord development GO:0021510 4 0.083
regulation of epithelial cell proliferation GO:0050678 113 0.082
ras protein signal transduction GO:0007265 73 0.082
cell fate determination GO:0001709 3 0.082
response to lipid GO:0033993 206 0.081
Rat
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.079
negative regulation of cell migration GO:0030336 102 0.078
response to oxygen containing compound GO:1901700 369 0.078
Rat
cellular response to growth factor stimulus GO:0071363 197 0.078
blood vessel morphogenesis GO:0048514 162 0.078
positive regulation of kinase activity GO:0033674 204 0.077
positive regulation of hydrolase activity GO:0051345 331 0.077
cellular response to dna damage stimulus GO:0006974 379 0.075
skeletal system development GO:0001501 79 0.073
positive regulation of cell motility GO:2000147 177 0.072
small gtpase mediated signal transduction GO:0007264 78 0.072
cellular component morphogenesis GO:0032989 314 0.072
Mouse Rat
positive regulation of hormone biosynthetic process GO:0046886 4 0.072
positive regulation of cellular component movement GO:0051272 181 0.071
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.069
regulation of cellular component biogenesis GO:0044087 281 0.069
muscle structure development GO:0061061 98 0.069
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.068
mesonephric duct development GO:0072177 3 0.068
regulation of biomineral tissue development GO:0070167 31 0.068
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.068
positive regulation of cellular catabolic process GO:0031331 284 0.067
cytoplasmic transport GO:0016482 379 0.066
ossification GO:0001503 121 0.066
blood vessel development GO:0001568 172 0.065
positive regulation of glucocorticoid biosynthetic process GO:0031948 1 0.065
response to organic cyclic compound GO:0014070 204 0.065
Rat
angiogenesis GO:0001525 147 0.064
small molecule biosynthetic process GO:0044283 157 0.064
cellular cation homeostasis GO:0030003 163 0.064
cell morphogenesis involved in differentiation GO:0000904 144 0.064
Mouse Rat
tissue morphogenesis GO:0048729 96 0.063
kidney development GO:0001822 53 0.063
embryonic morphogenesis GO:0048598 85 0.063
purine nucleoside catabolic process GO:0006152 398 0.062
mitotic cell cycle GO:0000278 326 0.062
regulation of secretion GO:0051046 194 0.062
positive regulation of odontogenesis GO:0042482 3 0.062
testosterone biosynthetic process GO:0061370 2 0.062
regulation of male gonad development GO:2000018 4 0.062
segmentation GO:0035282 4 0.061
positive regulation of apoptotic process GO:0043065 246 0.061
negative regulation of cellular protein metabolic process GO:0032269 353 0.060
bone mineralization GO:0030282 34 0.060
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.060
negative regulation of locomotion GO:0040013 118 0.059
forebrain regionalization GO:0021871 3 0.059
muscle tissue development GO:0060537 62 0.059
hemopoiesis GO:0030097 180 0.059
positive regulation of programmed cell death GO:0043068 249 0.059
epithelial cell proliferation GO:0050673 128 0.059
positive regulation of organelle organization GO:0010638 195 0.058
regulation of protein transport GO:0051223 213 0.057
secretion by cell GO:0032940 226 0.057
nucleoside triphosphate catabolic process GO:0009143 394 0.057
paramesonephric duct development GO:0061205 2 0.056
nucleoside triphosphate metabolic process GO:0009141 422 0.056
embryonic forelimb morphogenesis GO:0035115 4 0.056
regulation of cell development GO:0060284 161 0.056
Mouse
regulation of protein serine threonine kinase activity GO:0071900 179 0.055
regulation of ossification GO:0030278 58 0.055
osteoblast differentiation GO:0001649 92 0.055
regulation of establishment of protein localization GO:0070201 242 0.054
positive regulation of nucleotide metabolic process GO:0045981 230 0.053
protein localization to organelle GO:0033365 280 0.052
cellular response to oxygen containing compound GO:1901701 276 0.052
Rat
regulation of nucleotide metabolic process GO:0006140 269 0.052
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.052
neuron differentiation GO:0030182 138 0.052
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.052
regulation of cellular response to stress GO:0080135 244 0.052
mesenchymal cell development GO:0014031 50 0.052
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.052
cellular response to lipid GO:0071396 127 0.052
Rat
biological adhesion GO:0022610 331 0.051
negative regulation of testicular blood vessel morphogenesis GO:0061369 1 0.051
glycosyl compound catabolic process GO:1901658 413 0.051
micturition GO:0060073 3 0.051
positive regulation of tooth mineralization GO:0070172 2 0.051
ribonucleotide catabolic process GO:0009261 405 0.050
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.050
purine ribonucleoside metabolic process GO:0046128 437 0.050
hormone secretion GO:0046879 65 0.050
organic hydroxy compound metabolic process GO:1901615 147 0.050
connective tissue development GO:0061448 39 0.050
regulation of secretion by cell GO:1903530 177 0.050
cell projection organization GO:0030030 252 0.049
single organism cellular localization GO:1902580 332 0.049
regulation of cell adhesion GO:0030155 166 0.049
positive regulation of cell death GO:0010942 263 0.049
secretion GO:0046903 254 0.049
regulation of purine nucleotide metabolic process GO:1900542 264 0.049
intracellular protein transport GO:0006886 270 0.049
response to hormone GO:0009725 175 0.049
Rat
cell differentiation in spinal cord GO:0021515 1 0.048
negative regulation of phosphate metabolic process GO:0045936 267 0.048
locomotory behavior GO:0007626 1 0.048
negative regulation of androgen biosynthetic process GO:2000180 1 0.048
negative regulation of protein modification process GO:0031400 200 0.048
ribonucleoside triphosphate metabolic process GO:0009199 412 0.047
vasculature development GO:0001944 181 0.047
cytokine production GO:0001816 247 0.047
purine nucleoside triphosphate metabolic process GO:0009144 412 0.047
positive regulation of cytokine production GO:0001819 167 0.047
morphogenesis of an epithelium GO:0002009 60 0.047
regulation of cytokine production GO:0001817 232 0.047
ribonucleoside triphosphate catabolic process GO:0009203 391 0.046
regulation of homeostatic process GO:0032844 121 0.046
activation of protein kinase activity GO:0032147 90 0.046
cartilage condensation GO:0001502 1 0.045
regulation of cell cycle process GO:0010564 266 0.045
regulation of mitotic cell cycle GO:0007346 189 0.045
cellular homeostasis GO:0019725 196 0.045
positive regulation of transport GO:0051050 336 0.045
ribonucleoside catabolic process GO:0042454 406 0.045
mitotic cell cycle process GO:1903047 286 0.045
response to wounding GO:0009611 168 0.045
Rat
nitrogen compound transport GO:0071705 191 0.045
lipid biosynthetic process GO:0008610 177 0.045
positive regulation of cell migration GO:0030335 172 0.044
gland development GO:0048732 48 0.044
kidney morphogenesis GO:0060993 19 0.044
generation of neurons GO:0048699 152 0.044
regulation of purine nucleotide catabolic process GO:0033121 205 0.043
head development GO:0060322 108 0.043
Rat
cellular macromolecule catabolic process GO:0044265 380 0.043
negative regulation of phosphorus metabolic process GO:0010563 267 0.043
sex determination GO:0007530 3 0.043
central nervous system development GO:0007417 123 0.043
Rat
negative regulation of cellular component movement GO:0051271 106 0.043
cellular chemical homeostasis GO:0055082 180 0.042
purine nucleotide catabolic process GO:0006195 405 0.042
metal ion transport GO:0030001 272 0.042
protein catabolic process GO:0030163 325 0.042
nucleotide catabolic process GO:0009166 408 0.042
negative regulation of cell cycle GO:0045786 193 0.042
biomineral tissue development GO:0031214 39 0.041
cellular ion homeostasis GO:0006873 168 0.041
steroid biosynthetic process GO:0006694 46 0.041
hormone metabolic process GO:0042445 61 0.041
regulation of cell morphogenesis GO:0022604 153 0.041
Mouse
renal system development GO:0072001 63 0.041
cation transport GO:0006812 331 0.041
reproductive process GO:0022414 106 0.041
Rat
purine ribonucleotide catabolic process GO:0009154 404 0.041
growth GO:0040007 202 0.040
female gamete generation GO:0007292 2 0.040
regulation of bone mineralization GO:0030500 29 0.040
purine ribonucleoside catabolic process GO:0046130 398 0.040
immune response GO:0006955 307 0.040
regulation of proteolysis GO:0030162 293 0.040
transmembrane transport GO:0055085 399 0.040
nucleoside catabolic process GO:0009164 408 0.040
heart development GO:0007507 95 0.040
brain development GO:0007420 97 0.040
Rat
erk1 and erk2 cascade GO:0070371 104 0.040
regulation of erk1 and erk2 cascade GO:0070372 99 0.039
blastoderm segmentation GO:0007350 2 0.039
cardiac right ventricle morphogenesis GO:0003215 3 0.039
neurogenesis GO:0022008 169 0.039
positive regulation of protein transport GO:0051222 135 0.039
hindbrain development GO:0030902 3 0.039
purine containing compound catabolic process GO:0072523 411 0.039
negative regulation of male gonad development GO:2000019 1 0.039
multicellular organismal aging GO:0010259 3 0.039
gtp metabolic process GO:0046039 239 0.039
organophosphate catabolic process GO:0046434 430 0.039
ion homeostasis GO:0050801 230 0.039
positive regulation of cellular component biogenesis GO:0044089 158 0.039
morphogenesis of embryonic epithelium GO:0016331 4 0.039
carbohydrate derivative biosynthetic process GO:1901137 207 0.038
inner ear morphogenesis GO:0042472 4 0.038
androgen biosynthetic process GO:0006702 3 0.038
positive regulation of immune system process GO:0002684 283 0.038
striated muscle tissue development GO:0014706 59 0.038
cell aggregation GO:0098743 1 0.038
negative regulation of cell motility GO:2000146 104 0.038
regulation of nucleotide catabolic process GO:0030811 205 0.038
embryo development GO:0009790 123 0.037
regulation of lipid metabolic process GO:0019216 96 0.037
oogenesis GO:0048477 2 0.037
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.037
cellular metal ion homeostasis GO:0006875 146 0.037
neuromuscular junction development GO:0007528 3 0.037
regulation of intracellular transport GO:0032386 195 0.037
hindlimb morphogenesis GO:0035137 2 0.036
male gonad development GO:0008584 23 0.036
Rat
calcium ion homeostasis GO:0055074 122 0.036
protein targeting GO:0006605 187 0.036
epithelial tube morphogenesis GO:0060562 38 0.036
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.036
regulation of vasculature development GO:1901342 97 0.036
nucleoside phosphate catabolic process GO:1901292 412 0.036
actin cytoskeleton organization GO:0030036 207 0.035
regulation of growth GO:0040008 165 0.035
actin filament based process GO:0030029 224 0.035
peptidyl tyrosine phosphorylation GO:0018108 170 0.035
negative regulation of kidney development GO:0090185 2 0.035
negative regulation of catalytic activity GO:0043086 335 0.035
regulation of small gtpase mediated signal transduction GO:0051056 156 0.035
gtp catabolic process GO:0006184 237 0.035
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.035
purine nucleoside triphosphate catabolic process GO:0009146 392 0.034
nucleocytoplasmic transport GO:0006913 176 0.034
epithelium migration GO:0090132 119 0.034
regulation of testosterone biosynthetic process GO:2000224 2 0.034
cellular divalent inorganic cation homeostasis GO:0072503 128 0.034
epithelial to mesenchymal transition GO:0001837 48 0.034
wnt signaling pathway GO:0016055 156 0.034
establishment of protein localization to organelle GO:0072594 172 0.034
peptide transport GO:0015833 74 0.033
protein maturation GO:0051604 233 0.033
nuclear transport GO:0051169 179 0.033
determination of adult lifespan GO:0008340 2 0.033
embryonic epithelial tube formation GO:0001838 4 0.033
chemotaxis GO:0006935 157 0.033
canonical wnt signaling pathway GO:0060070 116 0.033
single organism cell adhesion GO:0098602 179 0.033
neurological system process GO:0050877 163 0.033
tissue migration GO:0090130 119 0.033
regulation of cytoplasmic transport GO:1903649 149 0.033
single organism reproductive process GO:0044702 98 0.033
Rat
protein modification by small protein conjugation GO:0032446 342 0.032
guanosine containing compound catabolic process GO:1901069 239 0.032
regulation of odontogenesis GO:0042481 4 0.032
positive regulation of cytoplasmic transport GO:1903651 82 0.032
regulation of ion homeostasis GO:2000021 73 0.032
positive regulation of cell cycle GO:0045787 140 0.032
peptidyl tyrosine modification GO:0018212 170 0.032
positive regulation of glucocorticoid metabolic process GO:0031945 1 0.032
nerve development GO:0021675 4 0.032
epithelial cell differentiation GO:0030855 141 0.032
Mouse Rat
chromatin organization GO:0006325 351 0.032
protein import into nucleus GO:0006606 104 0.032
development of primary male sexual characteristics GO:0046546 23 0.032
Rat
regulation of canonical wnt signaling pathway GO:0060828 88 0.031
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.031
muscle organ development GO:0007517 56 0.031
cation homeostasis GO:0055080 189 0.031
regulation of stem cell differentiation GO:2000736 56 0.031
response to cytokine GO:0034097 232 0.031
cell growth GO:0016049 160 0.031
negative regulation of cellular component organization GO:0051129 235 0.031
protein localization to nucleus GO:0034504 136 0.031
regulation of protein localization to nucleus GO:1900180 85 0.031
cellular lipid metabolic process GO:0044255 303 0.030
positive regulation of nucleotide catabolic process GO:0030813 185 0.030
epithelial cell migration GO:0010631 119 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
metencephalon development GO:0022037 2 0.030
protein processing GO:0016485 226 0.030
amide transport GO:0042886 76 0.030
regulation of wnt signaling pathway GO:0030111 123 0.030
regulation of gtpase activity GO:0043087 180 0.030
muscle contraction GO:0006936 73 0.030
Mouse
lung alveolus development GO:0048286 4 0.030
kidney epithelium development GO:0072073 25 0.030
calcium ion transport GO:0006816 147 0.030
cardiac muscle cell fate commitment GO:0060923 4 0.030
regulation of ras protein signal transduction GO:0046578 155 0.030
muscle cell fate commitment GO:0042693 4 0.030
covalent chromatin modification GO:0016569 254 0.030
wnt signaling pathway involved in wound healing spreading of epidermal cells GO:0035659 1 0.029
apoptotic signaling pathway GO:0097190 268 0.029
regeneration GO:0031099 4 0.029
positive regulation of dermatome development GO:0061184 3 0.029
single organism nuclear import GO:1902593 104 0.029
regulation of nucleoside metabolic process GO:0009118 209 0.029
nephric duct development GO:0072176 4 0.029
regulation of cytoskeleton organization GO:0051493 177 0.029
ameboidal type cell migration GO:0001667 135 0.029
negative regulation of protein phosphorylation GO:0001933 140 0.029
cellular response to hormone stimulus GO:0032870 125 0.029
Rat
cell cycle phase transition GO:0044770 173 0.029
protein ubiquitination GO:0016567 314 0.029
metal ion homeostasis GO:0055065 169 0.029
sensory perception of pain GO:0019233 4 0.029
membrane organization GO:0061024 292 0.029
Mouse
endocrine system development GO:0035270 26 0.029
positive regulation of lipid metabolic process GO:0045834 50 0.028
cellular response to cytokine stimulus GO:0071345 181 0.028
cell projection morphogenesis GO:0048858 129 0.028
nephron epithelium morphogenesis GO:0072088 15 0.028
rho protein signal transduction GO:0007266 26 0.028
positive regulation of gtp catabolic process GO:0033126 166 0.028
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.028
somatic stem cell maintenance GO:0035019 4 0.028
cellular macromolecular complex assembly GO:0034622 324 0.028
sequestering of metal ion GO:0051238 24 0.028
cranial nerve development GO:0021545 4 0.028
ion transmembrane transport GO:0034220 338 0.028
leukocyte differentiation GO:0002521 98 0.028
myeloid cell differentiation GO:0030099 117 0.028
muscle cell differentiation GO:0042692 63 0.028
negative regulation of cell cycle process GO:0010948 121 0.028
heart morphogenesis GO:0003007 48 0.028
regulation of endopeptidase activity GO:0052548 170 0.027
sensory perception GO:0007600 103 0.027
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.027
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.027
mesonephros development GO:0001823 17 0.027
regulation of epithelial cell migration GO:0010632 93 0.027
guanosine containing compound metabolic process GO:1901068 244 0.027
renal system pattern specification GO:0072048 1 0.027
hormone transport GO:0009914 68 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.027
taxis GO:0042330 157 0.027
cellular calcium ion homeostasis GO:0006874 117 0.027
alcohol metabolic process GO:0006066 114 0.027
regulation of gtp catabolic process GO:0033124 180 0.027
regulation of actin filament based process GO:0032970 141 0.027
regulation of intracellular protein transport GO:0033157 123 0.026
regulation of response to wounding GO:1903034 101 0.026
cell activation GO:0001775 213 0.026
regulation of dna metabolic process GO:0051052 153 0.026
positive regulation of nucleoside metabolic process GO:0045979 186 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
histone modification GO:0016570 251 0.026
cloacal septation GO:0060197 1 0.026
positive regulation of cell development GO:0010720 92 0.026
Mouse
steroid metabolic process GO:0008202 94 0.026
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.026
cartilage development GO:0051216 31 0.026
limb bud formation GO:0060174 1 0.026
positive regulation of proteolysis GO:0045862 142 0.026
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.026
divalent inorganic cation homeostasis GO:0072507 136 0.026
organic hydroxy compound biosynthetic process GO:1901617 71 0.026
neuron development GO:0048666 113 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.025
motor neuron axon guidance GO:0008045 2 0.025
positive regulation of ras gtpase activity GO:0032320 117 0.025
regionalization GO:0003002 29 0.025
Mouse
leukocyte migration GO:0050900 107 0.025
regulation of map kinase activity GO:0043405 108 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.025
negative regulation of growth GO:0045926 97 0.025
maintenance of location GO:0051235 112 0.025
negative regulation of transport GO:0051051 176 0.025
positive regulation of gtpase activity GO:0043547 166 0.025
cellular protein catabolic process GO:0044257 261 0.025
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.025
Mouse Rat
divalent metal ion transport GO:0070838 152 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.025
Mouse
regulation of muscle cell differentiation GO:0051147 31 0.024
response to other organism GO:0051707 261 0.024
endothelial cell migration GO:0043542 86 0.024
negative regulation of cell growth GO:0030308 83 0.024
renal tubule morphogenesis GO:0061333 14 0.024
single organism membrane organization GO:0044802 268 0.024
Mouse
behavior GO:0007610 112 0.024
cytosolic calcium ion homeostasis GO:0051480 89 0.024
response to biotic stimulus GO:0009607 276 0.024
regulation of protein targeting GO:1903533 91 0.024
protein import GO:0017038 130 0.024
regulation of lipid biosynthetic process GO:0046890 47 0.024
developmental process involved in reproduction GO:0003006 66 0.024
Rat
reactive oxygen species biosynthetic process GO:1903409 4 0.024
reactive oxygen species metabolic process GO:0072593 75 0.024
stress activated protein kinase signaling cascade GO:0031098 94 0.024
dephosphorylation GO:0016311 209 0.024
digestive system development GO:0055123 75 0.024
reactive nitrogen species metabolic process GO:2001057 3 0.024
heart formation GO:0060914 2 0.024
anterior posterior axis specification GO:0009948 2 0.024
regulation of response to external stimulus GO:0032101 222 0.024
regulation of myeloid cell differentiation GO:0045637 81 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
oxidative stress induced premature senescence GO:0090403 3 0.024
myeloid leukocyte differentiation GO:0002573 60 0.024
protein acylation GO:0043543 138 0.024
reproductive system development GO:0061458 56 0.023
Rat
embryonic hindlimb morphogenesis GO:0035116 2 0.023
neuroblast proliferation GO:0007405 4 0.023
carbohydrate metabolic process GO:0005975 207 0.023
digestive tract development GO:0048565 75 0.023
regulation of cell growth GO:0001558 135 0.023
hair follicle morphogenesis GO:0031069 2 0.023
ventral spinal cord development GO:0021517 1 0.023
mitotic cell cycle phase transition GO:0044772 162 0.023
photoreceptor cell differentiation GO:0046530 2 0.023
striated muscle cell differentiation GO:0051146 43 0.023
embryonic camera type eye development GO:0031076 2 0.023
mesodermal cell fate specification GO:0007501 2 0.023
defense response GO:0006952 315 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
signal release GO:0023061 70 0.023
dna replication GO:0006260 116 0.023
sequestering of calcium ion GO:0051208 17 0.022
cell substrate adhesion GO:0031589 132 0.022
regulation of hormone metabolic process GO:0032350 14 0.022
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.022
chromatin modification GO:0016568 298 0.022
response to external biotic stimulus GO:0043207 261 0.022
response to oxygen levels GO:0070482 100 0.022
peripheral nervous system development GO:0007422 2 0.022
Mouse
regulation of nervous system development GO:0051960 88 0.022
leukocyte activation GO:0045321 164 0.022
nephron tubule morphogenesis GO:0072078 13 0.022

GDNF disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.046
disease of metabolism DOID:0014667 295 0.029
sensory system disease DOID:0050155 203 0.026
nervous system disease DOID:863 431 0.026
bone disease DOID:0080001 88 0.023
connective tissue disease DOID:65 109 0.023
inherited metabolic disorder DOID:655 242 0.022