|
|
response to unfolded protein
|
GO:0006986 |
24 |
1.000
|
Yeast Mouse Worm |
|
|
cellular response to unfolded protein
|
GO:0034620 |
16 |
1.000
|
Mouse Worm |
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.999
|
Mouse Worm |
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.999
|
Mouse Worm |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.991
|
Yeast Mouse |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.990
|
Yeast |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.989
|
Yeast Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.981
|
Yeast |
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.967
|
Mouse Worm |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.962
|
Yeast Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.955
|
Yeast |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.950
|
Yeast |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.946
|
Yeast |
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.941
|
Mouse Rat Worm |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.915
|
Yeast |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.890
|
Yeast |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.872
|
Yeast |
|
|
endoplasmic reticulum organization
|
GO:0007029 |
20 |
0.809
|
|
|
|
intracellular protein transmembrane transport
|
GO:0065002 |
24 |
0.785
|
Yeast |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.770
|
Worm |
|
|
protein folding
|
GO:0006457 |
38 |
0.740
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.724
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.720
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.692
|
Yeast Mouse Worm |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.690
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.685
|
Yeast Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.679
|
Yeast |
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
31 |
0.640
|
Yeast |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.632
|
Yeast |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.618
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.610
|
Yeast |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.600
|
|
|
|
protein transmembrane transport
|
GO:0071806 |
25 |
0.587
|
Yeast |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.577
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.576
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.537
|
Yeast |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.526
|
|
|
|
regulation of atpase activity
|
GO:0043462 |
25 |
0.519
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.509
|
Yeast |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.488
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.482
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.457
|
Yeast |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.455
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.437
|
Yeast |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.426
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.424
|
Yeast |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.393
|
Yeast |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.354
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.349
|
Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.333
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.327
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.324
|
Yeast |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.316
|
Yeast |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.315
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.312
|
Yeast |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.294
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.290
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.289
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.285
|
Yeast |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.276
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.271
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.270
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.252
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.245
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.245
|
Yeast |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.243
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.240
|
Yeast |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.239
|
|
|
|
system process
|
GO:0003008 |
349 |
0.233
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.224
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.221
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.218
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.214
|
Yeast |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.214
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.213
|
Worm |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.212
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.205
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.204
|
Yeast |
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.196
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.195
|
Yeast |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.193
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.188
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.188
|
|
|
|
chaperone mediated protein folding
|
GO:0061077 |
13 |
0.180
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.178
|
Yeast |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.177
|
Yeast |
|
|
intracellular protein transmembrane import
|
GO:0044743 |
23 |
0.172
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.172
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.171
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.171
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.168
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.167
|
Yeast |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.161
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.160
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.158
|
Yeast |
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
12 |
0.157
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.156
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.156
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.153
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.152
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.146
|
Yeast |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.145
|
Yeast |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.140
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.137
|
|
|
|
growth
|
GO:0040007 |
202 |
0.135
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.135
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.132
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.132
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.132
|
Yeast |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.127
|
|
|
|
positive regulation of blood pressure
|
GO:0045777 |
3 |
0.127
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.124
|
|
|
|
regulation of atp metabolic process
|
GO:1903578 |
29 |
0.124
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.123
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.123
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.123
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.117
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.114
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.114
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.112
|
Yeast |
|
|
immune response
|
GO:0006955 |
307 |
0.111
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.110
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.110
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.106
|
Yeast |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.105
|
Yeast |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.105
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.104
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.103
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.099
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.095
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.093
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.092
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.091
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.090
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.087
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.086
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.084
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.083
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.083
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.083
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.082
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.081
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.081
|
Yeast |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.080
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.080
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.079
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.079
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.079
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.075
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.075
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.073
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.072
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.071
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.069
|
Worm |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.069
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.068
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.067
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.067
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.067
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.066
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.066
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.065
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.065
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.064
|
|
|
|
srp dependent cotranslational protein targeting to membrane
|
GO:0006614 |
2 |
0.064
|
Yeast |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.063
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.062
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.062
|
|
|
|
protein targeting to membrane
|
GO:0006612 |
42 |
0.062
|
Yeast |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.061
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.061
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.060
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.060
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.059
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.059
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.058
|
|
|
|
aging
|
GO:0007568 |
66 |
0.058
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.057
|
Yeast |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.057
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.056
|
Yeast |
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.056
|
Yeast |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.055
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.055
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.054
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.052
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.052
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.052
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.051
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.051
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.050
|
Yeast |
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.050
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.050
|
Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.049
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.049
|
|
|
|
translation
|
GO:0006412 |
132 |
0.049
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.049
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.048
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.045
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.044
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.044
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.044
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.044
|
|
|
|
positive regulation of systemic arterial blood pressure
|
GO:0003084 |
2 |
0.043
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.043
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.043
|
|
|
|
ear development
|
GO:0043583 |
14 |
0.042
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.042
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.042
|
Yeast |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.042
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.041
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.039
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.039
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.039
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.038
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.038
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.037
|
Yeast |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.036
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.036
|
|
|
|
regulation of acute inflammatory response to antigenic stimulus
|
GO:0002864 |
1 |
0.036
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.036
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.036
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.035
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.035
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.035
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.035
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.034
|
Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.034
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.034
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.034
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.033
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.033
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.033
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.033
|
|
|
|
protein refolding
|
GO:0042026 |
14 |
0.033
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.033
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.033
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.032
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.032
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.032
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.031
|
Mouse |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.031
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.031
|
Yeast |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.030
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.030
|
Yeast |
|
|
inner ear development
|
GO:0048839 |
8 |
0.029
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.029
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.029
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.028
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.028
|
|
|
|
de novo protein folding
|
GO:0006458 |
2 |
0.028
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.028
|
Mouse |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.028
|
|
|
|
head development
|
GO:0060322 |
108 |
0.027
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.027
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.027
|
Yeast |
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.027
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.027
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.027
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.027
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.027
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.027
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.026
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.026
|
Mouse |
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.025
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.025
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.025
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.025
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.025
|
|
|
|
male genitalia development
|
GO:0030539 |
1 |
0.025
|
|
|
|
lactation
|
GO:0007595 |
3 |
0.024
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.024
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.024
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.024
|
|
|
|
protein targeting to er
|
GO:0045047 |
7 |
0.023
|
Yeast |
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.023
|
|
|
|
protein targeting to mitochondrion
|
GO:0006626 |
19 |
0.023
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.023
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.023
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.023
|
Mouse |
|
|
negative regulation of nitric oxide synthase biosynthetic process
|
GO:0051771 |
3 |
0.023
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.022
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.022
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.022
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.022
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.022
|
|
|
|
eye pigmentation
|
GO:0048069 |
1 |
0.022
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.022
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.022
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.022
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.022
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.022
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.022
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.021
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.021
|
Yeast Worm |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.021
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.021
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.021
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.021
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.021
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.021
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.021
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.021
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.021
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.021
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.020
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.020
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.020
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.020
|
Mouse |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.020
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.020
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.020
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.020
|
|
|
|
inclusion body assembly
|
GO:0070841 |
17 |
0.020
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.020
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.019
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.019
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.019
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.019
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.019
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.019
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.019
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.018
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.018
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.018
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.018
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.018
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.018
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.018
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.018
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.018
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.018
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.018
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.018
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.018
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.017
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.017
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.017
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.017
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.017
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.017
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.017
|
Worm |
|
|
response to disaccharide
|
GO:0034285 |
1 |
0.017
|
|
|
|
negative regulation of neurological system process
|
GO:0031645 |
2 |
0.017
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.017
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.017
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.017
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.017
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.016
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.016
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.016
|
|
|
|
golgi inheritance
|
GO:0048313 |
2 |
0.016
|
|
|
|
positive regulation of atp catabolic process
|
GO:1903291 |
19 |
0.016
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.016
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.016
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.016
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.016
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.016
|
|
|
|
regulation of response to osmotic stress
|
GO:0047484 |
3 |
0.016
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.016
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.015
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.015
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.015
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.015
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.015
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.015
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.015
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.015
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.015
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.014
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.014
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.014
|
|
|
|
cotranslational protein targeting to membrane
|
GO:0006613 |
2 |
0.014
|
Yeast |
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.014
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.014
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.014
|
Mouse |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.014
|
|
|
|
response to electrical stimulus
|
GO:0051602 |
1 |
0.014
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.014
|
Mouse |
|
|
spermatid development
|
GO:0007286 |
4 |
0.014
|
|
|
|
misfolded protein transport
|
GO:0070843 |
1 |
0.014
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.013
|
|
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
19 |
0.013
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.013
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.013
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.013
|
Mouse |
|
|
endocytosis
|
GO:0006897 |
159 |
0.013
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.013
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.013
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.013
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.013
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.013
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.013
|
|
|
|
regulation of phosphoprotein phosphatase activity
|
GO:0043666 |
23 |
0.013
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.013
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.013
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.013
|
Yeast |
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.013
|
Yeast |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.013
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.013
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.013
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.013
|
|
|
|
heat acclimation
|
GO:0010286 |
3 |
0.013
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.012
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.012
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.012
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.012
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.012
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
25 |
0.012
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.012
|
|
|
|
negative regulation of translation
|
GO:0017148 |
37 |
0.012
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.012
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.012
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.012
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.012
|
|
|
|
peptidyl asparagine modification
|
GO:0018196 |
11 |
0.012
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.012
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
22 |
0.012
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.012
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.012
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.012
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.012
|
|
|
|
response to atp
|
GO:0033198 |
10 |
0.011
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.011
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.011
|
|
|
|
vasoconstriction
|
GO:0042310 |
11 |
0.011
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.011
|
Zebrafish Mouse |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.011
|
|
|
|
negative regulation of homotypic cell cell adhesion
|
GO:0034111 |
3 |
0.011
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.011
|
Mouse |
|
|
heart development
|
GO:0007507 |
95 |
0.011
|
|
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.011
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.011
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.011
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.011
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.011
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.011
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.011
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.011
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.011
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.011
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
3 |
0.011
|
|
|
|
positive regulation of atpase activity
|
GO:0032781 |
19 |
0.010
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.010
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.010
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.010
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.010
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.010
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.010
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.010
|
|
|
|
gamete generation
|
GO:0007276 |
25 |
0.010
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.010
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
1 |
0.010
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.010
|
Yeast |
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.010
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.010
|
|
