Homo sapiens

39 known processes

CHAF1A

chromatin assembly factor 1, subunit A (p150)

(Aliases: CAF1P150,CAF1B,CAF1,MGC71229,CAF-1,P150)

CHAF1A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleosome organization GO:0034728 66 0.999
dna replication dependent nucleosome assembly GO:0006335 32 0.998
protein dna complex assembly GO:0065004 64 0.998
chromatin assembly or disassembly GO:0006333 78 0.996
dna replication GO:0006260 116 0.994
histone exchange GO:0043486 3 0.985
dna repair GO:0006281 198 0.978
nucleosome assembly GO:0006334 50 0.977
cellular response to dna damage stimulus GO:0006974 379 0.973
chromatin assembly GO:0031497 61 0.968
dna packaging GO:0006323 77 0.962
nucleotide excision repair GO:0006289 31 0.955
regulation of mitosis GO:0007088 63 0.943
dna replication independent nucleosome assembly GO:0006336 27 0.933
dna replication independent nucleosome organization GO:0034724 27 0.920
dna conformation change GO:0071103 113 0.902
chromatin organization GO:0006325 351 0.886
mitotic cell cycle GO:0000278 326 0.871
atp catabolic process GO:0006200 157 0.867
base excision repair GO:0006284 21 0.865
dna replication dependent nucleosome organization GO:0034723 32 0.839
covalent chromatin modification GO:0016569 254 0.827
chromosome segregation GO:0007059 114 0.826
regulation of cell cycle phase transition GO:1901987 126 0.805
dna strand elongation involved in dna replication GO:0006271 3 0.787
dna dependent dna replication GO:0006261 44 0.777
mitotic cell cycle process GO:1903047 286 0.766
regulation of gene silencing GO:0060968 24 0.760
mitotic nuclear division GO:0007067 119 0.722
mitotic cell cycle phase transition GO:0044772 162 0.709
negative regulation of mitotic cell cycle GO:0045930 102 0.693
dna replication initiation GO:0006270 6 0.685
dna hypermethylation GO:0044026 1 0.608
positive regulation of dna templated transcription elongation GO:0032786 18 0.605
double strand break repair GO:0006302 101 0.598
lagging strand elongation GO:0006273 3 0.593
cell cycle phase transition GO:0044770 173 0.590
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.577
regulation of mitotic sister chromatid segregation GO:0033047 27 0.518
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.479
determination of adult lifespan GO:0008340 2 0.475
peptidyl lysine methylation GO:0018022 37 0.474
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.470
peptidyl lysine dimethylation GO:0018027 3 0.456
dna synthesis involved in dna repair GO:0000731 6 0.445
histone modification GO:0016570 251 0.435
proteasomal protein catabolic process GO:0010498 176 0.433
mitotic sister chromatid segregation GO:0000070 53 0.431
g2 dna damage checkpoint GO:0031572 26 0.426
protein dna complex subunit organization GO:0071824 80 0.400
cellular protein catabolic process GO:0044257 261 0.398
post embryonic development GO:0009791 2 0.384
cellular component disassembly GO:0022411 92 0.375
regulation of cell cycle GO:0051726 393 0.363
mitotic sister chromatid separation GO:0051306 18 0.356
chromatin remodeling GO:0006338 55 0.345
growth GO:0040007 202 0.342
chromatin silencing GO:0006342 12 0.317
positive regulation of chromatin modification GO:1903310 30 0.308
nervous system development GO:0007399 293 0.300
protein catabolic process GO:0030163 325 0.287
positive regulation of mitotic cell cycle GO:0045931 60 0.279
sister chromatid segregation GO:0000819 54 0.275
gene silencing GO:0016458 49 0.274
regulation of meiotic cell cycle GO:0051445 4 0.269
nucleoside triphosphate catabolic process GO:0009143 394 0.268
organelle fission GO:0048285 149 0.265
cell cycle checkpoint GO:0000075 117 0.259
dna biosynthetic process GO:0071897 40 0.242
cellular macromolecular complex assembly GO:0034622 324 0.242
mitotic dna integrity checkpoint GO:0044774 30 0.241
positive regulation of dna metabolic process GO:0051054 73 0.231
digestive system development GO:0055123 75 0.225
regulation of mitotic sister chromatid separation GO:0010965 27 0.219
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.214
dna damage checkpoint GO:0000077 68 0.212
atp metabolic process GO:0046034 176 0.210
mitotic cell cycle checkpoint GO:0007093 68 0.203
regulation of chromosome segregation GO:0051983 44 0.200
meiosis i GO:0007127 4 0.199
positive regulation of heterochromatin assembly GO:0031453 1 0.196
negative regulation of dna metabolic process GO:0051053 57 0.193
sensory organ development GO:0007423 52 0.190
regulation of mitotic cell cycle phase transition GO:1901990 118 0.189
internal protein amino acid acetylation GO:0006475 101 0.188
organophosphate catabolic process GO:0046434 430 0.182
glycosyl compound catabolic process GO:1901658 413 0.180
ribonucleoside triphosphate catabolic process GO:0009203 391 0.180
response to external biotic stimulus GO:0043207 261 0.179
nucleoside monophosphate catabolic process GO:0009125 159 0.178
cellular amino acid metabolic process GO:0006520 116 0.173
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.172
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.171
retina development in camera type eye GO:0060041 15 0.168
ras protein signal transduction GO:0007265 73 0.167
metaphase anaphase transition of cell cycle GO:0044784 21 0.163
negative regulation of gene expression epigenetic GO:0045814 19 0.161
chromosome separation GO:0051304 23 0.159
ubiquitin dependent protein catabolic process GO:0006511 206 0.157
regulation of chromosome organization GO:0033044 103 0.155
cell development GO:0048468 328 0.149
immune response GO:0006955 307 0.145
atp dependent chromatin remodeling GO:0043044 25 0.144
regulation of chromatin organization GO:1902275 56 0.143
positive regulation of organelle organization GO:0010638 195 0.139
regulation of histone h3 k9 methylation GO:0051570 6 0.136
regulation of mitotic cell cycle GO:0007346 189 0.135
eye development GO:0001654 42 0.135
regulation of proteasomal protein catabolic process GO:0061136 87 0.135
nuclear division GO:0000280 128 0.126
protein alkylation GO:0008213 74 0.126
g1 s transition of mitotic cell cycle GO:0000082 78 0.126
ribonucleoside catabolic process GO:0042454 406 0.124
nucleotide catabolic process GO:0009166 408 0.124
reproductive process GO:0022414 106 0.123
histone h2b ubiquitination GO:0033523 8 0.122
regulation of binding GO:0051098 111 0.122
multicellular organismal aging GO:0010259 3 0.121
replicative cell aging GO:0001302 3 0.119
negative regulation of cell cycle phase transition GO:1901988 89 0.116
nucleoside catabolic process GO:0009164 408 0.114
negative regulation of cell cycle process GO:0010948 121 0.113
regulation of multicellular organism growth GO:0040014 8 0.113
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.112
regulation of growth GO:0040008 165 0.111
mitotic dna damage checkpoint GO:0044773 28 0.110
regulation of dna metabolic process GO:0051052 153 0.109
regulation of gene expression epigenetic GO:0040029 73 0.108
g2 m transition of mitotic cell cycle GO:0000086 41 0.108
single organism reproductive process GO:0044702 98 0.107
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.106
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.106
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.102
regulation of cellular ketone metabolic process GO:0010565 50 0.098
dephosphorylation GO:0016311 209 0.098
response to biotic stimulus GO:0009607 276 0.097
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.094
dna strand elongation GO:0022616 5 0.093
cellular macromolecule catabolic process GO:0044265 380 0.091
regulation of cell cycle process GO:0010564 266 0.091
purine containing compound catabolic process GO:0072523 411 0.091
negative regulation of cell differentiation GO:0045596 171 0.089
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.088
double strand break repair via nonhomologous end joining GO:0006303 10 0.087
regulation of dna replication GO:0006275 68 0.086
cell cycle g2 m phase transition GO:0044839 43 0.086
gene conversion GO:0035822 1 0.086
purine nucleoside triphosphate catabolic process GO:0009146 392 0.085
histone h4 k20 methylation GO:0034770 1 0.084
positive regulation of chromosome organization GO:2001252 41 0.083
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.081
developmental process involved in reproduction GO:0003006 66 0.081
chromatin modification GO:0016568 298 0.080
ribonucleoside triphosphate metabolic process GO:0009199 412 0.078
positive regulation of cellular component organization GO:0051130 376 0.078
modification dependent macromolecule catabolic process GO:0043632 212 0.077
internal peptidyl lysine acetylation GO:0018393 97 0.077
maintenance of dna repeat elements GO:0043570 4 0.076
purine nucleoside triphosphate metabolic process GO:0009144 412 0.074
negative regulation of cell cycle GO:0045786 193 0.074
rna catabolic process GO:0006401 71 0.074
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.073
mitotic sister chromatid cohesion GO:0007064 12 0.073
positive regulation of cell cycle process GO:0090068 106 0.071
regulation of sister chromatid segregation GO:0033045 27 0.070
negative regulation of cellular catabolic process GO:0031330 83 0.068
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.068
purine ribonucleoside catabolic process GO:0046130 398 0.064
single organism cellular localization GO:1902580 332 0.064
sex determination GO:0007530 3 0.063
positive regulation of developmental process GO:0051094 314 0.063
negative regulation of catabolic process GO:0009895 104 0.063
heterochromatin organization GO:0070828 6 0.063
positive regulation of hydrolase activity GO:0051345 331 0.063
cell type specific apoptotic process GO:0097285 125 0.062
embryonic organ development GO:0048568 36 0.060
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.059
ribonucleotide catabolic process GO:0009261 405 0.058
ribonucleoside monophosphate metabolic process GO:0009161 187 0.058
purine nucleoside catabolic process GO:0006152 398 0.058
camera type eye development GO:0043010 25 0.058
cellular response to endogenous stimulus GO:0071495 336 0.058
cell cycle g1 s phase transition GO:0044843 80 0.058
reproductive structure development GO:0048608 55 0.056
stem cell development GO:0048864 69 0.055
heterochromatin assembly GO:0031507 6 0.054
rna splicing GO:0008380 131 0.054
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.054
male meiosis GO:0007140 1 0.053
nucleoside phosphate catabolic process GO:1901292 412 0.051
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.051
meiotic cell cycle GO:0051321 13 0.050
positive regulation of notch signaling pathway GO:0045747 6 0.049
double strand break repair via homologous recombination GO:0000724 50 0.049
response to abiotic stimulus GO:0009628 336 0.048
regulation of cell cycle g1 s phase transition GO:1902806 42 0.048
regulation of proteolysis GO:0030162 293 0.047
nucleoside triphosphate metabolic process GO:0009141 422 0.047
purine ribonucleotide catabolic process GO:0009154 404 0.047
cell cycle arrest GO:0007050 71 0.045
negative regulation of organelle organization GO:0010639 126 0.045
cytoplasmic transport GO:0016482 379 0.043
positive regulation of cell cycle GO:0045787 140 0.043
reproduction GO:0000003 63 0.042
negative regulation of sister chromatid segregation GO:0033046 17 0.042
telomere maintenance GO:0000723 32 0.041
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.041
response to uv GO:0009411 73 0.040
response to organic cyclic compound GO:0014070 204 0.040
anatomical structure homeostasis GO:0060249 100 0.040
cell fate determination GO:0001709 3 0.040
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.040
positive regulation of cell proliferation GO:0008284 301 0.039
aging GO:0007568 66 0.038
cellular component morphogenesis GO:0032989 314 0.038
positive regulation of cellular amine metabolic process GO:0033240 7 0.038
cell growth GO:0016049 160 0.037
spermatid differentiation GO:0048515 4 0.037
response to other organism GO:0051707 261 0.036
histone methylation GO:0016571 60 0.035
regulation of establishment of protein localization GO:0070201 242 0.035
cellular response to inorganic substance GO:0071241 45 0.034
vesicle mediated transport GO:0016192 371 0.034
nucleoside monophosphate metabolic process GO:0009123 191 0.034
spermatid development GO:0007286 4 0.033
response to inorganic substance GO:0010035 127 0.033
regulation of dna methylation GO:0044030 2 0.033
positive regulation of chromatin assembly or disassembly GO:0045799 2 0.033
ribonucleoside monophosphate catabolic process GO:0009158 158 0.032
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.032
protein processing GO:0016485 226 0.031
tube development GO:0035295 125 0.031
modification dependent protein catabolic process GO:0019941 209 0.031
neurogenesis GO:0022008 169 0.031
autophagic cell death GO:0048102 3 0.031
digestive tract morphogenesis GO:0048546 56 0.031
regulation of cellular amino acid metabolic process GO:0006521 6 0.031
regulation of protein catabolic process GO:0042176 155 0.030
cellular response to organic cyclic compound GO:0071407 127 0.030
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.030
regulation of cellular amine metabolic process GO:0033238 11 0.030
neuron differentiation GO:0030182 138 0.029
peptidyl lysine modification GO:0018205 144 0.029
embryo development GO:0009790 123 0.029
Worm
regulation of histone modification GO:0031056 47 0.029
digestive tract development GO:0048565 75 0.028
negative regulation of mitosis GO:0045839 24 0.028
oogenesis GO:0048477 2 0.028
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
regulation of nucleotide metabolic process GO:0006140 269 0.027
positive regulation of growth GO:0045927 58 0.027
regeneration GO:0031099 4 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.027
regulation of protein maturation GO:1903317 150 0.027
small gtpase mediated signal transduction GO:0007264 78 0.026
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.026
non recombinational repair GO:0000726 14 0.026
positive regulation of catabolic process GO:0009896 310 0.026
actin filament based process GO:0030029 224 0.026
regulation of microtubule cytoskeleton organization GO:0070507 61 0.025
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.025
intracellular protein transport GO:0006886 270 0.025
methylation GO:0032259 106 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
regulation of dna templated transcription elongation GO:0032784 23 0.024
positive regulation of cell cycle phase transition GO:1901989 22 0.024
negative regulation of cell division GO:0051782 31 0.023
rna processing GO:0006396 255 0.023
protein maturation GO:0051604 233 0.023
purine nucleoside monophosphate catabolic process GO:0009128 158 0.023
regulation of cellular component biogenesis GO:0044087 281 0.023
regulation of transcription by chromatin organization GO:0034401 1 0.023
histone lysine methylation GO:0034968 50 0.023
regulation of mrna metabolic process GO:1903311 53 0.023
cell aging GO:0007569 52 0.022
exit from mitosis GO:0010458 10 0.022
positive regulation of multicellular organism growth GO:0040018 6 0.022
dna modification GO:0006304 27 0.021
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.021
dna integrity checkpoint GO:0031570 71 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
purine nucleoside monophosphate metabolic process GO:0009126 186 0.021
mitotic g2 dna damage checkpoint GO:0007095 7 0.021
protein acetylation GO:0006473 116 0.021
oocyte maturation GO:0001556 1 0.021
histone h3 k9 methylation GO:0051567 10 0.021
positive regulation of developmental growth GO:0048639 16 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
macromolecule methylation GO:0043414 97 0.020
multi organism reproductive process GO:0044703 54 0.020
regulation of protein transport GO:0051223 213 0.019
nucleus organization GO:0006997 28 0.019
microtubule based process GO:0007017 210 0.019
organelle assembly GO:0070925 176 0.019
blastocyst development GO:0001824 3 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
regulation of protein localization GO:0032880 296 0.019
reproductive system development GO:0061458 56 0.019
cell division GO:0051301 168 0.019
developmental growth GO:0048589 48 0.018
regulation of histone methylation GO:0031060 16 0.018
sex differentiation GO:0007548 45 0.018
spermatogenesis GO:0007283 22 0.018
cellular protein complex assembly GO:0043623 188 0.018
response to fungus GO:0009620 4 0.018
multi multicellular organism process GO:0044706 18 0.018
cell morphogenesis GO:0000902 296 0.018
mrna processing GO:0006397 133 0.018
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.018
positive regulation of transport GO:0051050 336 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.017
biological adhesion GO:0022610 331 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
multicellular organism growth GO:0035264 8 0.016
axon cargo transport GO:0008088 2 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
positive regulation of immune system process GO:0002684 283 0.016
microtubule organizing center organization GO:0031023 62 0.016
regulation of cellular protein catabolic process GO:1903362 96 0.016
regulation of nuclear division GO:0051783 65 0.016
positive regulation of cytoplasmic transport GO:1903651 82 0.016
macromolecular complex disassembly GO:0032984 60 0.016
embryo development ending in birth or egg hatching GO:0009792 34 0.015
Worm
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
cell projection organization GO:0030030 252 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
negative regulation of proteolysis GO:0045861 132 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
positive regulation of proteolysis GO:0045862 142 0.014
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.014
humoral immune response GO:0006959 49 0.014
regulation of dna dependent dna replication initiation GO:0030174 3 0.014
dna recombination GO:0006310 77 0.014
behavior GO:0007610 112 0.014
histone acetylation GO:0016573 93 0.013
regulation of cell division GO:0051302 116 0.013
membrane organization GO:0061024 292 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
sexual reproduction GO:0019953 37 0.013
regulation of notch signaling pathway GO:0008593 18 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
dna templated transcription elongation GO:0006354 25 0.013
negative regulation of chromatin modification GO:1903309 21 0.013
telomere organization GO:0032200 33 0.013
regulation of transferase activity GO:0051338 355 0.013
development of primary sexual characteristics GO:0045137 35 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
protein localization to organelle GO:0033365 280 0.013
myosin filament organization GO:0031033 2 0.012
endocytosis GO:0006897 159 0.012
response to light stimulus GO:0009416 87 0.012
generation of neurons GO:0048699 152 0.012
mitotic g2 m transition checkpoint GO:0044818 9 0.012
regulation of chromatin modification GO:1903308 51 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
regulation of cell growth GO:0001558 135 0.012
positive regulation of response to dna damage stimulus GO:2001022 43 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
lymphocyte activation GO:0046649 133 0.011
myosin filament assembly GO:0031034 2 0.011
positive regulation of immune response GO:0050778 159 0.011
dna catabolic process GO:0006308 49 0.011
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 15 0.011
protein complex disassembly GO:0043241 52 0.011
transcription factor import into nucleus GO:0042991 40 0.011
negative regulation of cell size GO:0045792 3 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
response to ionizing radiation GO:0010212 65 0.011
male gamete generation GO:0048232 22 0.011
regulation of protein processing GO:0070613 150 0.011
peripheral nervous system development GO:0007422 2 0.011
nucleotide biosynthetic process GO:0009165 109 0.010
response to extracellular stimulus GO:0009991 85 0.010
positive regulation of gtpase activity GO:0043547 166 0.010
signal transduction in response to dna damage GO:0042770 57 0.010
response to oxygen containing compound GO:1901700 369 0.010
regulation of kinase activity GO:0043549 314 0.010
regulation of chromatin silencing GO:0031935 8 0.010
regulation of immune response GO:0050776 201 0.010
positive regulation of cell death GO:0010942 263 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
stem cell differentiation GO:0048863 93 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010

CHAF1A disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.158
disease of cellular proliferation DOID:14566 174 0.158
organ system cancer DOID:0050686 164 0.158
gastrointestinal system cancer DOID:3119 52 0.013