Homo sapiens

24 known processes

XPO6

exportin 6

(Aliases: RANBP20,KIAA0370,EXP6,FLJ22519)

XPO6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 78 0.234
negative regulation of protein metabolic process GO:0051248 391 0.233
vesicle mediated transport GO:0016192 371 0.155
regulation of small gtpase mediated signal transduction GO:0051056 156 0.147
post embryonic development GO:0009791 2 0.137
mitotic cell cycle GO:0000278 326 0.125
female gamete generation GO:0007292 2 0.125
microtubule cytoskeleton organization GO:0000226 176 0.123
single organism cellular localization GO:1902580 332 0.116
nucleoside catabolic process GO:0009164 408 0.095
negative regulation of phosphorus metabolic process GO:0010563 267 0.092
regulation of transferase activity GO:0051338 355 0.090
microtubule based process GO:0007017 210 0.084
cellular amino acid metabolic process GO:0006520 116 0.083
negative regulation of cell proliferation GO:0008285 228 0.081
mapk cascade GO:0000165 288 0.080
i kappab kinase nf kappab signaling GO:0007249 166 0.078
regulation of protein localization GO:0032880 296 0.077
regulation of ras protein signal transduction GO:0046578 155 0.077
regulation of cellular amine metabolic process GO:0033238 11 0.076
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.075
regulation of kinase activity GO:0043549 314 0.074
regulation of cellular amino acid metabolic process GO:0006521 6 0.073
regulation of protein serine threonine kinase activity GO:0071900 179 0.072
negative regulation of catalytic activity GO:0043086 335 0.072
regulation of mapk cascade GO:0043408 262 0.070
negative regulation of cell death GO:0060548 345 0.066
negative regulation of programmed cell death GO:0043069 321 0.066
cellular amine metabolic process GO:0044106 41 0.065
nucleoside triphosphate metabolic process GO:0009141 422 0.064
oogenesis GO:0048477 2 0.064
ras protein signal transduction GO:0007265 73 0.064
mitotic cell cycle process GO:1903047 286 0.063
negative regulation of phosphorylation GO:0042326 174 0.062
negative regulation of protein phosphorylation GO:0001933 140 0.060
negative regulation of cellular protein metabolic process GO:0032269 353 0.058
segmentation GO:0035282 4 0.058
cellular protein complex assembly GO:0043623 188 0.056
negative regulation of phosphate metabolic process GO:0045936 267 0.056
cytoplasmic transport GO:0016482 379 0.056
purine nucleotide catabolic process GO:0006195 405 0.053
cellular ketone metabolic process GO:0042180 80 0.049
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.049
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.049
cellular macromolecular complex assembly GO:0034622 324 0.048
negative regulation of intracellular signal transduction GO:1902532 183 0.048
cellular response to histamine GO:0071420 3 0.048
organelle localization GO:0051640 84 0.047
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.046
negative regulation of protein kinase activity GO:0006469 98 0.046
negative regulation of apoptotic process GO:0043066 316 0.046
negative regulation of protein modification process GO:0031400 200 0.045
regulation of map kinase activity GO:0043405 108 0.045
negative regulation of transferase activity GO:0051348 124 0.045
endocytosis GO:0006897 159 0.045
single organism membrane organization GO:0044802 268 0.042
blastoderm segmentation GO:0007350 2 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
innate immune response GO:0045087 178 0.041
signal transduction by phosphorylation GO:0023014 297 0.040
protein localization to organelle GO:0033365 280 0.040
purine nucleoside catabolic process GO:0006152 398 0.040
enzyme linked receptor protein signaling pathway GO:0007167 303 0.039
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
ribonucleoside monophosphate metabolic process GO:0009161 187 0.037
purine containing compound catabolic process GO:0072523 411 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.036
purine nucleoside triphosphate catabolic process GO:0009146 392 0.035
purine nucleoside triphosphate metabolic process GO:0009144 412 0.035
membrane organization GO:0061024 292 0.035
ribonucleotide catabolic process GO:0009261 405 0.034
cell aging GO:0007569 52 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.033
atp catabolic process GO:0006200 157 0.033
anterior posterior axis specification GO:0009948 2 0.033
purine nucleoside monophosphate catabolic process GO:0009128 158 0.033
actin filament based process GO:0030029 224 0.033
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
ribonucleoside catabolic process GO:0042454 406 0.032
nucleoside triphosphate catabolic process GO:0009143 394 0.032
ribonucleoprotein complex biogenesis GO:0022613 116 0.032
metal ion transport GO:0030001 272 0.032
regulation of locomotion GO:0040012 329 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.031
negative regulation of kinase activity GO:0033673 106 0.031
anterior posterior axis specification embryo GO:0008595 2 0.031
ribonucleoside triphosphate metabolic process GO:0009199 412 0.031
protein catabolic process GO:0030163 325 0.030
cell division GO:0051301 168 0.030
multicellular organismal aging GO:0010259 3 0.030
spermatid development GO:0007286 4 0.030
amine metabolic process GO:0009308 44 0.030
oocyte development GO:0048599 1 0.029
cell adhesion GO:0007155 325 0.029
ncrna processing GO:0034470 83 0.029
nucleoside monophosphate metabolic process GO:0009123 191 0.029
maintenance of location GO:0051235 112 0.029
purine nucleoside monophosphate metabolic process GO:0009126 186 0.028
oocyte differentiation GO:0009994 2 0.028
regulation of mitotic cell cycle GO:0007346 189 0.028
biological adhesion GO:0022610 331 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.027
cation transport GO:0006812 331 0.027
regulation of establishment of protein localization GO:0070201 242 0.027
transmembrane transport GO:0055085 399 0.027
spermatid differentiation GO:0048515 4 0.026
actin cytoskeleton organization GO:0030036 207 0.026
anatomical structure formation involved in morphogenesis GO:0048646 284 0.025
regulation of cell division GO:0051302 116 0.025
purine ribonucleoside catabolic process GO:0046130 398 0.025
thymus development GO:0048538 3 0.025
regulation of cell cycle GO:0051726 393 0.025
response to fungus GO:0009620 4 0.025
positive regulation of nucleotide metabolic process GO:0045981 230 0.024
endomembrane system organization GO:0010256 196 0.024
cell development GO:0048468 328 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
response to nitrogen compound GO:1901698 184 0.024
organophosphate catabolic process GO:0046434 430 0.024
nucleotide catabolic process GO:0009166 408 0.024
tripartite regional subdivision GO:0007351 2 0.024
epithelium development GO:0060429 227 0.024
carbohydrate derivative biosynthetic process GO:1901137 207 0.024
protein polymerization GO:0051258 71 0.023
system process GO:0003008 349 0.023
Fly
response to external biotic stimulus GO:0043207 261 0.023
negative regulation of transport GO:0051051 176 0.023
regulation of nucleotide metabolic process GO:0006140 269 0.023
dephosphorylation GO:0016311 209 0.023
ncrna metabolic process GO:0034660 108 0.023
rna processing GO:0006396 255 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
regulation of cellular component movement GO:0051270 334 0.022
organic hydroxy compound metabolic process GO:1901615 147 0.022
nucleus organization GO:0006997 28 0.022
determination of adult lifespan GO:0008340 2 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.022
cellular homeostasis GO:0019725 196 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.022
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.021
actin mediated cell contraction GO:0070252 12 0.021
regulation of cell motility GO:2000145 299 0.021
nucleoside monophosphate catabolic process GO:0009125 159 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.021
regulation of ion transport GO:0043269 189 0.021
secretion by cell GO:0032940 226 0.021
guanosine containing compound metabolic process GO:1901068 244 0.021
cellular metal ion homeostasis GO:0006875 146 0.021
cellular lipid metabolic process GO:0044255 303 0.021
vesicle localization GO:0051648 26 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.020
cellular component morphogenesis GO:0032989 314 0.020
positive regulation of transport GO:0051050 336 0.020
lipid biosynthetic process GO:0008610 177 0.020
regulation of multi organism process GO:0043900 157 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
immune response GO:0006955 307 0.020
negative regulation of mapk cascade GO:0043409 56 0.020
positive regulation of organelle organization GO:0010638 195 0.020
lipid localization GO:0010876 106 0.020
negative regulation of map kinase activity GO:0043407 27 0.020
secretion GO:0046903 254 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.019
defense response GO:0006952 315 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
organelle assembly GO:0070925 176 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
reproductive process GO:0022414 106 0.019
mrna metabolic process GO:0016071 175 0.018
locomotory behavior GO:0007626 1 0.018
Fly
positive regulation of developmental process GO:0051094 314 0.018
organelle fission GO:0048285 149 0.018
meiosis i GO:0007127 4 0.018
cellular response to endogenous stimulus GO:0071495 336 0.018
cell projection organization GO:0030030 252 0.018
actin filament based movement GO:0030048 17 0.018
protein modification by small protein conjugation GO:0032446 342 0.017
protein homooligomerization GO:0051260 100 0.017
response to abiotic stimulus GO:0009628 336 0.017
response to organic cyclic compound GO:0014070 204 0.017
cellular cation homeostasis GO:0030003 163 0.017
regulation of protein catabolic process GO:0042176 155 0.017
embryonic epithelial tube formation GO:0001838 4 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
neural tube formation GO:0001841 3 0.017
response to oxygen containing compound GO:1901700 369 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
nuclear division GO:0000280 128 0.017
protein localization to membrane GO:0072657 160 0.017
regulation of erbb signaling pathway GO:1901184 27 0.016
regulation of intracellular transport GO:0032386 195 0.016
negative regulation of locomotion GO:0040013 118 0.016
regeneration GO:0031099 4 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
sequestering of metal ion GO:0051238 24 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
anion transport GO:0006820 161 0.016
neuromuscular junction development GO:0007528 3 0.016
cell morphogenesis GO:0000902 296 0.016
negative regulation of multi organism process GO:0043901 92 0.016
somatic muscle development GO:0007525 1 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
regulation of gene expression epigenetic GO:0040029 73 0.015
head development GO:0060322 108 0.015
Fly
regulation of epidermal growth factor receptor signaling pathway GO:0042058 27 0.015
adult locomotory behavior GO:0008344 1 0.015
Fly
positive regulation of cytoskeleton organization GO:0051495 83 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
epithelial cell differentiation GO:0030855 141 0.015
regulation of cell migration GO:0030334 289 0.015
cellular protein catabolic process GO:0044257 261 0.015
regulation of protein kinase activity GO:0045859 289 0.015
positive regulation of kinase activity GO:0033674 204 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
memory GO:0007613 3 0.015
Fly
maturation of ssu rrna GO:0030490 3 0.015
cellular chemical homeostasis GO:0055082 180 0.015
defense response to fungus GO:0050832 4 0.015
positive regulation of cell death GO:0010942 263 0.015
establishment of spindle orientation GO:0051294 9 0.015
actin filament organization GO:0007015 128 0.015
response to other organism GO:0051707 261 0.015
receptor mediated endocytosis GO:0006898 84 0.015
ion homeostasis GO:0050801 230 0.015
cellular macromolecule catabolic process GO:0044265 380 0.014
negative regulation of ras protein signal transduction GO:0046580 11 0.014
regulation of metal ion transport GO:0010959 120 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
regulation of microtubule based process GO:0032886 74 0.014
defense response to other organism GO:0098542 129 0.014
plasma membrane organization GO:0007009 115 0.014
histone modification GO:0016570 251 0.014
embryo development GO:0009790 123 0.014
divalent metal ion transport GO:0070838 152 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
chemical homeostasis GO:0048878 306 0.014
regulation of cell cycle process GO:0010564 266 0.014
atp metabolic process GO:0046034 176 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
positive regulation of neural precursor cell proliferation GO:2000179 2 0.014
carbohydrate metabolic process GO:0005975 207 0.014
intracellular protein transport GO:0006886 270 0.014
regulation of immune response GO:0050776 201 0.014
erbb signaling pathway GO:0038127 44 0.014
ribosome biogenesis GO:0042254 48 0.014
maintenance of location in cell GO:0051651 62 0.014
tube closure GO:0060606 3 0.014
positive regulation of immune system process GO:0002684 283 0.014
cell activation GO:0001775 213 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
ameboidal type cell migration GO:0001667 135 0.014
protein oligomerization GO:0051259 173 0.013
leukocyte activation GO:0045321 164 0.013
aging GO:0007568 66 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
regulation of cellular response to stress GO:0080135 244 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
negative regulation of small gtpase mediated signal transduction GO:0051058 12 0.013
reproduction GO:0000003 63 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
negative regulation of cell cycle GO:0045786 193 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
protein targeting GO:0006605 187 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
positive regulation of catabolic process GO:0009896 310 0.013
cellular response to ammonium ion GO:0071242 4 0.013
divalent inorganic cation homeostasis GO:0072507 136 0.013
anatomical structure homeostasis GO:0060249 100 0.013
peptidyl lysine acetylation GO:0018394 101 0.013
sequestering of calcium ion GO:0051208 17 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
regulation of protein transport GO:0051223 213 0.013
nitrogen compound transport GO:0071705 191 0.013
central nervous system development GO:0007417 123 0.012
Fly
protein localization to nucleus GO:0034504 136 0.012
cation homeostasis GO:0055080 189 0.012
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 11 0.012
synaptic vesicle localization GO:0097479 5 0.012
regulation of secretion by cell GO:1903530 177 0.012
cellular calcium ion homeostasis GO:0006874 117 0.012
cytokinesis GO:0000910 96 0.012
chromatin modification GO:0016568 298 0.012
neurological system process GO:0050877 163 0.012
Fly
primary neural tube formation GO:0014020 3 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
neural crest cell development GO:0014032 3 0.012
cell projection assembly GO:0030031 126 0.012
regulation of chromosome organization GO:0033044 103 0.012
regulation of homeostatic process GO:0032844 121 0.012
cytosolic calcium ion homeostasis GO:0051480 89 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
glycoprotein metabolic process GO:0009100 110 0.012
cellular response to organic cyclic compound GO:0071407 127 0.012
inner ear morphogenesis GO:0042472 4 0.012
neurotransmitter secretion GO:0007269 4 0.012
regulation of cell differentiation GO:0045595 393 0.012
brain development GO:0007420 97 0.012
Fly
response to radiation GO:0009314 151 0.012
response to biotic stimulus GO:0009607 276 0.012
positive regulation of immune response GO:0050778 159 0.012
alcohol metabolic process GO:0006066 114 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
regulation of cytokine production GO:0001817 232 0.012
interspecies interaction between organisms GO:0044419 156 0.012
cellular ion homeostasis GO:0006873 168 0.012
synaptic vesicle endocytosis GO:0048488 2 0.012
lipid metabolic process GO:0006629 381 0.011
cellular divalent inorganic cation homeostasis GO:0072503 128 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
maintenance of protein location in cell GO:0032507 56 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
lymphocyte activation GO:0046649 133 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
positive regulation of actin filament polymerization GO:0030838 38 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
multi organism cellular process GO:0044764 156 0.011
tissue migration GO:0090130 119 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
t cell differentiation in thymus GO:0033077 4 0.011
response to organonitrogen compound GO:0010243 156 0.011
striated muscle myosin thick filament assembly GO:0071688 2 0.011
stem cell differentiation GO:0048863 93 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
g protein coupled receptor signaling pathway GO:0007186 207 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
protein ubiquitination GO:0016567 314 0.011
negative regulation of viral process GO:0048525 66 0.011
neurogenesis GO:0022008 169 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.010
sensory perception GO:0007600 103 0.010
positive regulation of protein phosphorylation GO:0001934 313 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
inorganic ion transmembrane transport GO:0098660 231 0.010
neuron differentiation GO:0030182 138 0.010
small molecule biosynthetic process GO:0044283 157 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
myosin filament assembly GO:0031034 2 0.010
positive regulation of gtpase activity GO:0043547 166 0.010
regulation of viral process GO:0050792 103 0.010
engulfment of apoptotic cell GO:0043652 2 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010
gtp catabolic process GO:0006184 237 0.010
chromosome segregation GO:0007059 114 0.010
regulation of synaptic plasticity GO:0048167 3 0.010
regulation of rna splicing GO:0043484 62 0.010
cardiovascular system development GO:0072358 262 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
calcium ion homeostasis GO:0055074 122 0.010
regulation of cell projection organization GO:0031344 107 0.010

XPO6 disease predictions

Disease DO term ID Size Probability Func Analog Org
synucleinopathy DOID:0050890 22 0.170
central nervous system disease DOID:331 186 0.170
neurodegenerative disease DOID:1289 102 0.170
nervous system disease DOID:863 431 0.170
disease of metabolism DOID:0014667 295 0.025
carbohydrate metabolic disorder DOID:2978 55 0.025
inherited metabolic disorder DOID:655 242 0.025
sensory system disease DOID:0050155 203 0.021
auditory system disease DOID:2742 53 0.021
musculoskeletal system disease DOID:17 223 0.016
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
nonsyndromic deafness DOID:0050563 50 0.011