|
regulation of lamellipodium morphogenesis
|
GO:2000392 |
4 |
0.685
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.619
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.561
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.539
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.534
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.525
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.505
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.495
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.486
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.456
|
Fly |
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.456
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.449
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.424
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.399
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.398
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.363
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.345
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.340
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.331
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.321
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.316
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.302
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.287
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.286
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
2 |
0.281
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.279
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.271
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.267
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.256
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.253
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.240
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.235
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.224
|
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.220
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.209
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.205
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.201
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.197
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.193
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.177
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.175
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.172
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.172
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.169
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.167
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.166
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.155
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.148
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.146
|
Human |
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.146
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.143
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.138
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.135
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.134
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.133
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.131
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.130
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.120
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.119
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.113
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.112
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.110
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.110
|
Human |
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.110
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.108
|
Zebrafish |
|
post embryonic development
|
GO:0009791 |
2 |
0.105
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.105
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.105
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.104
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.104
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.103
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.102
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.101
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.100
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.097
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.096
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.095
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.095
|
Zebrafish |
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.095
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.092
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.090
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.088
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.088
|
|
|
segmentation
|
GO:0035282 |
4 |
0.088
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.087
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.087
|
Human |
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.086
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.086
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.084
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.083
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.083
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.083
|
|
|
cell development
|
GO:0048468 |
328 |
0.081
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.080
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.080
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.078
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.077
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.077
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.077
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.076
|
|
|
immune response
|
GO:0006955 |
307 |
0.074
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.073
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.073
|
Fly |
|
response to other organism
|
GO:0051707 |
261 |
0.073
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.072
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.071
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.071
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.070
|
Zebrafish |
|
activation of immune response
|
GO:0002253 |
114 |
0.070
|
|
|
astrocyte cell migration
|
GO:0043615 |
1 |
0.069
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.069
|
Human |
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.068
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.068
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.067
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.067
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.065
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.064
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.063
|
|
|
activation of mapkkk activity
|
GO:0000185 |
7 |
0.063
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.063
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.063
|
Zebrafish |
|
oocyte development
|
GO:0048599 |
1 |
0.062
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.061
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.060
|
Human |
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.060
|
Human |
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.060
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.058
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.057
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.056
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.056
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.056
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.055
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.055
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.054
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.053
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.053
|
|
|
post golgi vesicle mediated transport
|
GO:0006892 |
36 |
0.053
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.052
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.052
|
Zebrafish |
|
response to oxidative stress
|
GO:0006979 |
121 |
0.052
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.051
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.050
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.050
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.050
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.050
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.049
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.049
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.046
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.046
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.046
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.046
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.046
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.045
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.045
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.045
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.044
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.043
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.043
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.042
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.041
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.041
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.040
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.040
|
|
|
regulation of cd40 signaling pathway
|
GO:2000348 |
3 |
0.040
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.040
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.039
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.039
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.039
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.039
|
Human |
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.039
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.039
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.039
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.039
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.038
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.038
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.038
|
|
|
tachykinin receptor signaling pathway
|
GO:0007217 |
3 |
0.038
|
|
|
positive regulation of substrate adhesion dependent cell spreading
|
GO:1900026 |
15 |
0.038
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.038
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.038
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.038
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.037
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.037
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.037
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.037
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.037
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.037
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.036
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.036
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.036
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.035
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.035
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.035
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.035
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.035
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.035
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.034
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.034
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.034
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.034
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.034
|
|
|
rna interference
|
GO:0016246 |
4 |
0.034
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.034
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.034
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.033
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.033
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.033
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.033
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.033
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.033
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.033
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.033
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.033
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.033
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.032
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.032
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.032
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.032
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.032
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.031
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.031
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.031
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.031
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.031
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.031
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.030
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.030
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.030
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.030
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.029
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.029
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.029
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.029
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.029
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.029
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.029
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.028
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.028
|
Human |
|
regulation of protein localization
|
GO:0032880 |
296 |
0.028
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.028
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.028
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.028
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.028
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.027
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.027
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.027
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.027
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.027
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.027
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.027
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.027
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.027
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.027
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.027
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.027
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.026
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.026
|
Zebrafish |
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.026
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.026
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.026
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.025
|
Human |
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.025
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.025
|
|
|
cell activation
|
GO:0001775 |
213 |
0.025
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.025
|
|
|
cell growth
|
GO:0016049 |
160 |
0.025
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.025
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.025
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.025
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.025
|
Human |
|
positive regulation of transport
|
GO:0051050 |
336 |
0.024
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.024
|
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
4 |
0.024
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.024
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
13 |
0.024
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.024
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.024
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.024
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.024
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.024
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.024
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.024
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.023
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.023
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.023
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.023
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.023
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.023
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.023
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.023
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.023
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.023
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.023
|
|
|
positive regulation of focal adhesion assembly
|
GO:0051894 |
11 |
0.022
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.022
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.022
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.022
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.022
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.022
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.022
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.022
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.022
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.022
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.022
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.022
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.022
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.022
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.021
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.021
|
|
|
memory
|
GO:0007613 |
3 |
0.021
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.021
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.021
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.021
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.021
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.021
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.021
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.021
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.021
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.020
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.020
|
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
3 |
0.020
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.020
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.020
|
|
|
visual learning
|
GO:0008542 |
1 |
0.020
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.020
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.020
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.020
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.020
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.020
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.020
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.020
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.019
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.019
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.019
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.019
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.019
|
|
|
head development
|
GO:0060322 |
108 |
0.019
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.019
|
|
|
behavior
|
GO:0007610 |
112 |
0.019
|
Mouse |
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.019
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.019
|
|
|
positive regulation of lamellipodium morphogenesis
|
GO:2000394 |
2 |
0.019
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.019
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.019
|
|
|
brain development
|
GO:0007420 |
97 |
0.019
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.018
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.018
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.018
|
|
|
regeneration
|
GO:0031099 |
4 |
0.018
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.018
|
|
|
gene silencing by rna
|
GO:0031047 |
26 |
0.018
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.018
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.018
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.018
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.018
|
Mouse |
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.018
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.018
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.018
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.018
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.018
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.018
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.018
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.018
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.018
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.018
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.018
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.017
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.017
|
|
|
regulation of substrate adhesion dependent cell spreading
|
GO:1900024 |
19 |
0.017
|
|
|
immune system development
|
GO:0002520 |
195 |
0.017
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.017
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.017
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.017
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.017
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.017
|
|
|
protein processing
|
GO:0016485 |
226 |
0.017
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.017
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.017
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.017
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.017
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.017
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.017
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.016
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.016
|
Zebrafish |
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.016
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.016
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.016
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.016
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.016
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.016
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
3 |
0.016
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.016
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
25 |
0.016
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.016
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.016
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.016
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.016
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.016
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.016
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.016
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.016
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.016
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.015
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.015
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.015
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.015
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.015
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.015
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.015
|
|
|
negative regulation of striated muscle contraction
|
GO:0045988 |
2 |
0.015
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.015
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.015
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.015
|
Human |
|
system process
|
GO:0003008 |
349 |
0.015
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.015
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.015
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.015
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.015
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.015
|
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.015
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.015
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.015
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.015
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.015
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.015
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.015
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.015
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.015
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.014
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.014
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.014
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.014
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.014
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.014
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.014
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.014
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.014
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.014
|
Human |
|
cellular response to lipid
|
GO:0071396 |
127 |
0.014
|
|
|
regulation of lamellipodium organization
|
GO:1902743 |
19 |
0.014
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.014
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.014
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.014
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.014
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.014
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.014
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.014
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.014
|
Zebrafish |
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.014
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.014
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.014
|
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.014
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.014
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.014
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.014
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.014
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.014
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.013
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.013
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.013
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.013
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.013
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.013
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.013
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.013
|
|
|
nucleoside diphosphate metabolic process
|
GO:0009132 |
16 |
0.013
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.013
|
|
|
taxis
|
GO:0042330 |
157 |
0.013
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.013
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.013
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.013
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.013
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.013
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.013
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.013
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.013
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.013
|
|
|
wound healing
|
GO:0042060 |
115 |
0.013
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.013
|
|
|
thymus development
|
GO:0048538 |
3 |
0.013
|
|