Homo sapiens

78 known processes

SPARC

secreted protein, acidic, cysteine-rich (osteonectin)

(Aliases: ON)

SPARC biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
soft palate development GO:0060023 3 0.999
negative regulation of gastrulation GO:2000542 4 0.995
embryonic skeletal joint morphogenesis GO:0060272 2 0.992
embryonic skeletal joint development GO:0072498 2 0.982
regulation of endodermal cell differentiation GO:1903224 3 0.951
vasculature development GO:0001944 181 0.872
circulatory system development GO:0072359 262 0.864
detection of mechanical stimulus GO:0050982 4 0.820
endomembrane system organization GO:0010256 196 0.816
rho protein signal transduction GO:0007266 26 0.791
regulation of canonical wnt signaling pathway GO:0060828 88 0.785
positive regulation of stem cell differentiation GO:2000738 29 0.778
positive regulation of epithelial to mesenchymal transition GO:0010718 22 0.773
epithelial to mesenchymal transition GO:0001837 48 0.756
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.725
visual perception GO:0007601 27 0.721
canonical wnt signaling pathway GO:0060070 116 0.719
negative regulation of embryonic development GO:0045992 4 0.676
integrin mediated signaling pathway GO:0007229 32 0.657
membrane organization GO:0061024 292 0.655
single organismal cell cell adhesion GO:0016337 148 0.651
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.648
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.640
regulation of cell motility GO:2000145 299 0.607
blood vessel morphogenesis GO:0048514 162 0.593
cell matrix adhesion GO:0007160 85 0.579
detection of mechanical stimulus involved in sensory perception GO:0050974 1 0.578
wnt signaling pathway GO:0016055 156 0.577
ras protein signal transduction GO:0007265 73 0.571
endoderm development GO:0007492 33 0.556
sensory perception of light stimulus GO:0050953 35 0.552
cardiovascular system development GO:0072358 262 0.550
regulation of epithelial to mesenchymal transition GO:0010717 37 0.546
biological adhesion GO:0022610 331 0.545
plasma membrane organization GO:0007009 115 0.545
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.544
regulation of cellular component movement GO:0051270 334 0.542
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 1 0.539
response to transforming growth factor beta GO:0071559 94 0.533
cell development GO:0048468 328 0.531
negative regulation of endodermal cell differentiation GO:1903225 2 0.519
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.510
tissue morphogenesis GO:0048729 96 0.494
Zebrafish
response to oxygen containing compound GO:1901700 369 0.490
Rat
mesenchymal cell development GO:0014031 50 0.487
small gtpase mediated signal transduction GO:0007264 78 0.485
wound healing GO:0042060 115 0.475
Rat
single organism membrane organization GO:0044802 268 0.468
multicellular organismal metabolic process GO:0044236 34 0.457
anatomical structure formation involved in morphogenesis GO:0048646 284 0.448
positive regulation of wnt signaling pathway GO:0030177 54 0.444
regulation of stem cell differentiation GO:2000736 56 0.437
blood vessel development GO:0001568 172 0.436
cell adhesion GO:0007155 325 0.430
regulation of wnt signaling pathway GO:0030111 123 0.413
cellular response to nitrogen compound GO:1901699 144 0.410
response to nitrogen compound GO:1901698 184 0.402
Rat
multicellular organismal macromolecule metabolic process GO:0044259 29 0.400
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.393
cell substrate adhesion GO:0031589 132 0.380
integrin biosynthetic process GO:0045112 4 0.374
endoderm formation GO:0001706 33 0.372
epithelium development GO:0060429 227 0.364
Zebrafish
cellular response to growth factor stimulus GO:0071363 197 0.363
Mouse
organ morphogenesis GO:0009887 147 0.361
Zebrafish
peptide cross linking GO:0018149 12 0.349
negative regulation of developmental process GO:0051093 247 0.349
positive regulation of cellular component movement GO:0051272 181 0.348
protein localization to organelle GO:0033365 280 0.346
cellular component morphogenesis GO:0032989 314 0.345
circulatory system process GO:0003013 113 0.333
negative regulation of cell differentiation GO:0045596 171 0.327
positive regulation of cell migration GO:0030335 172 0.324
endodermal cell differentiation GO:0035987 31 0.320
detection of stimulus GO:0051606 85 0.317
cellular response to endogenous stimulus GO:0071495 336 0.316
mesenchymal cell differentiation GO:0048762 52 0.315
detection of abiotic stimulus GO:0009582 15 0.308
mesenchyme development GO:0060485 59 0.308
response to abiotic stimulus GO:0009628 336 0.297
Rat
negative regulation of multicellular organismal process GO:0051241 317 0.290
negative regulation of cell migration GO:0030336 102 0.289
response to growth factor GO:0070848 205 0.281
Mouse
positive regulation of cell motility GO:2000147 177 0.269
response to wounding GO:0009611 168 0.269
Rat
collagen fibril organization GO:0030199 10 0.261
regulation of gastrulation GO:0010470 12 0.258
negative regulation of immune system process GO:0002683 136 0.251
positive regulation of cellular component organization GO:0051130 376 0.249
blood circulation GO:0008015 113 0.236
formation of primary germ layer GO:0001704 42 0.224
sensory perception GO:0007600 103 0.220
collagen metabolic process GO:0032963 28 0.219
regulation of cell migration GO:0030334 289 0.217
biomineral tissue development GO:0031214 39 0.209
regulation of locomotion GO:0040012 329 0.209
cell morphogenesis involved in differentiation GO:0000904 144 0.206
response to radiation GO:0009314 151 0.203
morphogenesis of an epithelium GO:0002009 60 0.198
Zebrafish
cellular response to acid chemical GO:0071229 44 0.196
skin development GO:0043588 76 0.196
gastrulation GO:0007369 51 0.196
sensory perception of mechanical stimulus GO:0050954 37 0.190
tube morphogenesis GO:0035239 95 0.182
Zebrafish
negative regulation of cell adhesion GO:0007162 64 0.173
regeneration GO:0031099 4 0.172
regulation of cell development GO:0060284 161 0.169
stem cell development GO:0048864 69 0.167
cellular response to oxygen containing compound GO:1901701 276 0.163
angiogenesis GO:0001525 147 0.160
response to mechanical stimulus GO:0009612 51 0.160
cellular response to organonitrogen compound GO:0071417 124 0.156
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.156
regulation of immune response GO:0050776 201 0.155
post embryonic development GO:0009791 2 0.154
Worm
system process GO:0003008 349 0.153
tooth mineralization GO:0034505 6 0.150
odontogenesis GO:0042476 25 0.150
sensory perception of sound GO:0007605 37 0.148
regulation of anatomical structure morphogenesis GO:0022603 286 0.145
enzyme linked receptor protein signaling pathway GO:0007167 303 0.139
regulation of cell morphogenesis GO:0022604 153 0.138
stem cell differentiation GO:0048863 93 0.135
immune response GO:0006955 307 0.132
cellular response to amino acid stimulus GO:0071230 12 0.130
regulation of blood pressure GO:0008217 30 0.128
ossification GO:0001503 121 0.127
Rat
angiogenesis involved in wound healing GO:0060055 4 0.126
morphogenesis of an epithelial sheet GO:0002011 12 0.126
regulation of cell adhesion GO:0030155 166 0.126
digestive system development GO:0055123 75 0.123
positive regulation of cell differentiation GO:0045597 211 0.117
cellular amino acid metabolic process GO:0006520 116 0.115
muscle tissue morphogenesis GO:0060415 19 0.114
cartilage development GO:0051216 31 0.112
Zebrafish
regulation of cellular amine metabolic process GO:0033238 11 0.112
skin morphogenesis GO:0043589 6 0.111
detection of stimulus involved in sensory perception GO:0050906 43 0.110
regulation of cell differentiation GO:0045595 393 0.109
response to amino acid GO:0043200 14 0.108
aorta morphogenesis GO:0035909 1 0.105
extracellular matrix organization GO:0030198 41 0.104
extracellular fibril organization GO:0043206 7 0.104
tissue regeneration GO:0042246 3 0.104
fibril organization GO:0097435 10 0.100
response to nutrient levels GO:0031667 81 0.100
Rat
negative regulation of cell motility GO:2000146 104 0.100
positive regulation of cell development GO:0010720 92 0.097
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.097
negative regulation of hydrolase activity GO:0051346 182 0.097
nervous system development GO:0007399 293 0.096
negative regulation of protein metabolic process GO:0051248 391 0.094
collagen biosynthetic process GO:0032964 15 0.093
wound healing spreading of cells GO:0044319 8 0.093
digestive tract morphogenesis GO:0048546 56 0.091
ameboidal type cell migration GO:0001667 135 0.089
response to extracellular stimulus GO:0009991 85 0.088
Rat
neurological system process GO:0050877 163 0.088
positive regulation of rho protein signal transduction GO:0035025 4 0.087
positive regulation of locomotion GO:0040017 186 0.086
sensory organ development GO:0007423 52 0.085
Zebrafish Rat
basement membrane organization GO:0071711 3 0.084
negative regulation of blood vessel morphogenesis GO:2000181 41 0.083
negative regulation of immune response GO:0050777 40 0.082
negative regulation of peptidase activity GO:0010466 91 0.081
response to organonitrogen compound GO:0010243 156 0.081
Rat
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.080
digestive tract development GO:0048565 75 0.079
epithelial tube morphogenesis GO:0060562 38 0.079
cellular response to nutrient levels GO:0031669 69 0.078
protein localization to nucleus GO:0034504 136 0.077
heart morphogenesis GO:0003007 48 0.075
regulation of neuron migration GO:2001222 3 0.075
bone trabecula morphogenesis GO:0061430 1 0.070
skeletal system development GO:0001501 79 0.070
Zebrafish Mouse
cellular ketone metabolic process GO:0042180 80 0.070
detection of external stimulus GO:0009581 15 0.070
smooth muscle tissue development GO:0048745 3 0.070
cellular amine metabolic process GO:0044106 41 0.069
regulation of cellular amino acid metabolic process GO:0006521 6 0.067
regulation of secretion by cell GO:1903530 177 0.067
skeletal system morphogenesis GO:0048705 24 0.067
palate development GO:0060021 13 0.067
negative regulation of endopeptidase activity GO:0010951 84 0.064
regulation of cell substrate adhesion GO:0010810 68 0.062
regulation of cellular response to growth factor stimulus GO:0090287 76 0.062
aorta development GO:0035904 2 0.060
negative regulation of cell development GO:0010721 48 0.059
growth GO:0040007 202 0.059
Worm
muscle organ development GO:0007517 56 0.059
response to acid chemical GO:0001101 66 0.058
Rat
cell chemotaxis GO:0060326 112 0.058
bone trabecula formation GO:0060346 1 0.058
positive regulation of developmental process GO:0051094 314 0.058
Worm
negative regulation of cellular component movement GO:0051271 106 0.057
chordate embryonic development GO:0043009 34 0.057
Zebrafish
negative regulation of catalytic activity GO:0043086 335 0.056
apoptotic signaling pathway GO:0097190 268 0.056
cell morphogenesis GO:0000902 296 0.056
epiboly involved in wound healing GO:0090505 8 0.055
regulation of proteolysis GO:0030162 293 0.055
cellular response to hormone stimulus GO:0032870 125 0.054
regulation of peptidase activity GO:0052547 180 0.054
purine nucleoside catabolic process GO:0006152 398 0.054
patterning of blood vessels GO:0001569 2 0.053
positive regulation of aldosterone metabolic process GO:0032346 2 0.052
neuron projection regeneration GO:0031102 1 0.052
muscle contraction GO:0006936 73 0.052
negative regulation of programmed cell death GO:0043069 321 0.052
embryonic morphogenesis GO:0048598 85 0.052
Zebrafish
muscle organ morphogenesis GO:0048644 19 0.051
negative regulation of locomotion GO:0040013 118 0.050
morphogenesis of a branching structure GO:0001763 21 0.049
ribonucleoside catabolic process GO:0042454 406 0.048
regulation of rho protein signal transduction GO:0035023 79 0.048
regulation of protein transport GO:0051223 213 0.048
regulation of epithelial cell proliferation GO:0050678 113 0.048
heart development GO:0007507 95 0.048
Rat
response to nutrient GO:0007584 20 0.047
Rat
response to hydrogen peroxide GO:0042542 40 0.047
positive regulation of transport GO:0051050 336 0.047
purine containing compound catabolic process GO:0072523 411 0.046
regulation of embryonic development GO:0045995 20 0.046
response to hormone GO:0009725 175 0.046
Rat
positive regulation of cell proliferation GO:0008284 301 0.046
guanosine containing compound metabolic process GO:1901068 244 0.045
neuromuscular junction development GO:0007528 3 0.045
leukocyte migration GO:0050900 107 0.045
nucleotide catabolic process GO:0009166 408 0.044
negative regulation of proteolysis GO:0045861 132 0.044
protein catabolic process GO:0030163 325 0.042
response to cytokine GO:0034097 232 0.042
Rat
muscle tissue development GO:0060537 62 0.042
negative regulation of protein processing GO:0010955 142 0.042
regulation of protein binding GO:0043393 66 0.042
positive regulation of cell substrate adhesion GO:0010811 37 0.041
protein localization to membrane GO:0072657 160 0.041
cellular response to nutrient GO:0031670 12 0.039
ion transmembrane transport GO:0034220 338 0.039
protein maturation GO:0051604 233 0.039
endochondral bone morphogenesis GO:0060350 3 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.039
response to oxidative stress GO:0006979 121 0.038
nucleoside phosphate catabolic process GO:1901292 412 0.038
embryonic skeletal system development GO:0048706 13 0.038
negative regulation of trophoblast cell migration GO:1901164 3 0.038
positive regulation of transferase activity GO:0051347 227 0.038
regulation of nucleotide metabolic process GO:0006140 269 0.038
response to organic cyclic compound GO:0014070 204 0.038
Rat
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.037
mating GO:0007618 1 0.036
sprouting angiogenesis GO:0002040 29 0.036
cellular protein complex assembly GO:0043623 188 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.035
single organism cell adhesion GO:0098602 179 0.035
ribonucleoside triphosphate metabolic process GO:0009199 412 0.035
wound healing spreading of epidermal cells GO:0035313 6 0.035
regulation of endopeptidase activity GO:0052548 170 0.035
positive regulation of apoptotic signaling pathway GO:2001235 70 0.035
glycosyl compound catabolic process GO:1901658 413 0.034
determination of adult lifespan GO:0008340 2 0.034
positive regulation of cell death GO:0010942 263 0.034
protein processing GO:0016485 226 0.034
connective tissue development GO:0061448 39 0.033
Zebrafish
regulation of wound healing GO:0061041 56 0.032
negative regulation of vasculature development GO:1901343 43 0.032
negative regulation of protein maturation GO:1903318 142 0.032
response to hyperoxia GO:0055093 4 0.032
regulation of secretion GO:0051046 194 0.031
positive regulation of keratinocyte migration GO:0051549 4 0.031
negative regulation of apoptotic process GO:0043066 316 0.031
glial cell migration GO:0008347 4 0.031
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.031
extrinsic apoptotic signaling pathway GO:0097191 119 0.031
regulation of vasculature development GO:1901342 97 0.031
regulation of integrin mediated signaling pathway GO:2001044 3 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
membrane fusion GO:0061025 43 0.030
positive regulation of cell adhesion GO:0045785 84 0.029
cation transport GO:0006812 331 0.029
neurogenesis GO:0022008 169 0.029
protein oligomerization GO:0051259 173 0.029
modification dependent protein catabolic process GO:0019941 209 0.029
embryonic organ development GO:0048568 36 0.029
Zebrafish
purine nucleoside triphosphate catabolic process GO:0009146 392 0.029
taxis GO:0042330 157 0.029
single organism cellular localization GO:1902580 332 0.029
regulation of protein import into nucleus GO:0042306 78 0.028
purine nucleotide catabolic process GO:0006195 405 0.028
regulation of apoptotic signaling pathway GO:2001233 175 0.028
cerebral cortex cell migration GO:0021795 3 0.028
mitotic cell cycle process GO:1903047 286 0.028
purine ribonucleotide catabolic process GO:0009154 404 0.027
regulation of blood coagulation GO:0030193 42 0.027
embryonic skeletal system morphogenesis GO:0048704 9 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
embryonic organ morphogenesis GO:0048562 24 0.026
Zebrafish
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.026
eye morphogenesis GO:0048592 16 0.026
cellular response to extracellular stimulus GO:0031668 72 0.026
embryo development GO:0009790 123 0.026
Zebrafish Worm
leukocyte chemotaxis GO:0030595 76 0.025
striated muscle contraction GO:0006941 52 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
multicellular organismal aging GO:0010259 3 0.025
negative regulation of transport GO:0051051 176 0.025
female gamete generation GO:0007292 2 0.024
amine metabolic process GO:0009308 44 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.024
sensory perception of smell GO:0007608 2 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
regulation of cellular ketone metabolic process GO:0010565 50 0.024
cellular protein catabolic process GO:0044257 261 0.024
negative regulation of cell death GO:0060548 345 0.024
regulation of response to external stimulus GO:0032101 222 0.024
cell growth GO:0016049 160 0.023
response to lipid GO:0033993 206 0.023
Rat
negative regulation of apoptotic signaling pathway GO:2001234 97 0.023
urogenital system development GO:0001655 65 0.023
limb development GO:0060173 23 0.023
actin mediated cell contraction GO:0070252 12 0.023
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.023
transmembrane transport GO:0055085 399 0.023
actin filament based movement GO:0030048 17 0.023
endosomal transport GO:0016197 129 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
vesicle mediated transport GO:0016192 371 0.022
generation of neurons GO:0048699 152 0.022
regulation of ras protein signal transduction GO:0046578 155 0.022
reproductive process GO:0022414 106 0.022
regulation of epithelial cell migration GO:0010632 93 0.022
positive regulation of fibroblast migration GO:0010763 3 0.022
mapk cascade GO:0000165 288 0.022
cardiac muscle tissue morphogenesis GO:0055008 18 0.022
extracellular structure organization GO:0043062 41 0.022
establishment of protein localization to membrane GO:0090150 121 0.022
muscle system process GO:0003012 81 0.022
secretion GO:0046903 254 0.022
cerebral cortex development GO:0021987 10 0.021
engulfment of apoptotic cell GO:0043652 2 0.021
striated muscle cell differentiation GO:0051146 43 0.021
regulation of cellular response to stress GO:0080135 244 0.021
regulation of protein localization to plasma membrane GO:1903076 40 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
negative regulation of protein transport GO:0051224 75 0.021
epiboly GO:0090504 9 0.021
negative regulation of multi organism process GO:0043901 92 0.021
vesicle organization GO:0016050 62 0.021
negative regulation of neuron migration GO:2001223 1 0.021
response to reactive oxygen species GO:0000302 61 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
response to biotic stimulus GO:0009607 276 0.020
Rat
neuronal glial interaction involved in cerebral cortex radial glia guided migration GO:0021812 1 0.020
response to increased oxygen levels GO:0036296 4 0.020
cerebral cortex radially oriented cell migration GO:0021799 1 0.020
regulation of binding GO:0051098 111 0.020
glomerular mesangial cell differentiation GO:0072008 2 0.020
establishment of tissue polarity GO:0007164 3 0.020
positive regulation of catabolic process GO:0009896 310 0.020
cytokinesis GO:0000910 96 0.020
cell projection organization GO:0030030 252 0.020
receptor metabolic process GO:0043112 81 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
regulation of nervous system development GO:0051960 88 0.019
regulation of protein localization GO:0032880 296 0.019
gtp catabolic process GO:0006184 237 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.019
cardiac muscle contraction GO:0060048 34 0.019
lens development in camera type eye GO:0002088 2 0.019
regulation of protein maturation GO:1903317 150 0.019
neuron migration GO:0001764 11 0.019
negative regulation of neuron projection development GO:0010977 15 0.018
response to light stimulus GO:0009416 87 0.018
substrate adhesion dependent cell spreading GO:0034446 41 0.018
negative regulation of cell substrate adhesion GO:0010812 24 0.018
bmp signaling pathway GO:0030509 49 0.018
protein localization to plasma membrane GO:0072659 93 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
gtp metabolic process GO:0046039 239 0.018
pallium development GO:0021543 10 0.018
negative regulation of protein modification process GO:0031400 200 0.018
immune system development GO:0002520 195 0.018
zymogen activation GO:0031638 70 0.018
optokinetic behavior GO:0007634 1 0.017
nuclear transport GO:0051169 179 0.017
cellular response to external stimulus GO:0071496 111 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
sensory organ morphogenesis GO:0090596 21 0.017
Zebrafish
segmentation GO:0035282 4 0.017
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.017
response to external biotic stimulus GO:0043207 261 0.017
Rat
cardiac muscle tissue development GO:0048738 39 0.017
negative regulation of cell growth GO:0030308 83 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
oogenesis GO:0048477 2 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
cell cell junction organization GO:0045216 69 0.017
trabecula morphogenesis GO:0061383 2 0.017
retinal blood vessel morphogenesis GO:0061304 2 0.016
regulation of growth rate GO:0040009 1 0.016
regulation of transferase activity GO:0051338 355 0.016
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
salivary gland morphogenesis GO:0007435 4 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
protein import into nucleus GO:0006606 104 0.016
artery morphogenesis GO:0048844 7 0.016
viral life cycle GO:0019058 132 0.016
vascular wound healing GO:0061042 4 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
cellular response to abiotic stimulus GO:0071214 117 0.016
purine nucleoside monophosphate catabolic process GO:0009128 158 0.016
actin filament based process GO:0030029 224 0.016
organelle assembly GO:0070925 176 0.016
response to peptide GO:1901652 65 0.016
Rat
axon regeneration GO:0031103 1 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
erk1 and erk2 cascade GO:0070371 104 0.015
hematopoietic or lymphoid organ development GO:0048534 186 0.015
endocytosis GO:0006897 159 0.015
regulation of protein processing GO:0070613 150 0.015
multi organism cellular process GO:0044764 156 0.015
replacement ossification GO:0036075 1 0.015
regulation of protein catabolic process GO:0042176 155 0.015
muscle structure development GO:0061061 98 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
regulation of leukocyte activation GO:0002694 115 0.015
morphogenesis of a branching epithelium GO:0061138 20 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
protein homooligomerization GO:0051260 100 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
regulation of actin cytoskeleton organization GO:0032956 116 0.015
response to peptide hormone GO:0043434 61 0.015
Rat
regulation of actin filament based process GO:0032970 141 0.015
positive regulation of organelle organization GO:0010638 195 0.015
cell division GO:0051301 168 0.015
positive regulation of leukocyte chemotaxis GO:0002690 38 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
epidermis morphogenesis GO:0048730 3 0.015
positive regulation of secretion by cell GO:1903532 108 0.014
head development GO:0060322 108 0.014
nucleoside catabolic process GO:0009164 408 0.014
regulation of leukocyte chemotaxis GO:0002688 46 0.014
regulation of kinase activity GO:0043549 314 0.014
regulation of protein kinase activity GO:0045859 289 0.014
intracellular protein transport GO:0006886 270 0.014
negative regulation of cytokine production GO:0001818 82 0.014
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
atp catabolic process GO:0006200 157 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
eye development GO:0001654 42 0.014
cellular response to peptide hormone stimulus GO:0071375 56 0.014
response to steroid hormone GO:0048545 80 0.014
Rat
oxidation reduction process GO:0055114 396 0.014
negative regulation of protein secretion GO:0050709 29 0.014
positive regulation of hormone biosynthetic process GO:0046886 4 0.014
interspecies interaction between organisms GO:0044419 156 0.014
pharynx development GO:0060465 1 0.014
neural crest cell migration GO:0001755 2 0.014
regulation of cell growth GO:0001558 135 0.014
endochondral ossification GO:0001958 1 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
endothelial cell proliferation GO:0001935 65 0.014
regulation of multi organism process GO:0043900 157 0.014
regulation of leukocyte migration GO:0002685 63 0.014
neural crest cell development GO:0014032 3 0.014
positive regulation of protein kinase activity GO:0045860 190 0.013
branching involved in salivary gland morphogenesis GO:0060445 1 0.013
actin cytoskeleton organization GO:0030036 207 0.013
cyclic nucleotide metabolic process GO:0009187 82 0.013
coagulation GO:0050817 78 0.013
cellular response to glucocorticoid stimulus GO:0071385 4 0.013

SPARC disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.867
connective tissue disease DOID:65 109 0.867
collagen disease DOID:854 9 0.860
ehlers danlos syndrome DOID:13359 9 0.813
osteochondrodysplasia DOID:2256 35 0.356
osteogenesis imperfecta DOID:12347 13 0.356
bone development disease DOID:0080006 55 0.356
bone disease DOID:0080001 88 0.356
sensory system disease DOID:0050155 203 0.052
eye and adnexa disease DOID:1492 150 0.052
nervous system disease DOID:863 431 0.052
eye disease DOID:5614 149 0.052
retinal disease DOID:5679 118 0.021
retinal degeneration DOID:8466 89 0.021
bone remodeling disease DOID:0080005 26 0.017
disease of metabolism DOID:0014667 295 0.017
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015