Homo sapiens

248 known processes

BAX

BCL2-associated X protein

(Aliases: BCL2L4)

BAX biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 1.000
Human
positive regulation of oxidative stress induced cell death GO:1903209 5 0.999
Human
regulation of mitochondrion organization GO:0010821 54 0.999
release of cytochrome c from mitochondria GO:0001836 35 0.999
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.998
regulation of protein oligomerization GO:0032459 26 0.998
regulation of oxidative stress induced neuron death GO:1903203 9 0.998
Human
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.998
Human Mouse
apoptotic mitochondrial changes GO:0008637 57 0.997
modulation by virus of host morphology or physiology GO:0019048 10 0.997
Human
neuron death in response to oxidative stress GO:0036475 9 0.997
Human
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901030 3 0.997
mitochondrial membrane organization GO:0007006 40 0.997
Human Mouse Rat
positive regulation of mitochondrion organization GO:0010822 30 0.997
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902177 4 0.996
Human
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.996
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.996
positive regulation of apoptotic signaling pathway GO:2001235 70 0.996
positive regulation of response to oxidative stress GO:1902884 7 0.996
Human
regulation of execution phase of apoptosis GO:1900117 11 0.994
modulation of programmed cell death in other organism involved in symbiotic interaction GO:0052248 1 0.991
Human
positive regulation of protein oligomerization GO:0032461 17 0.991
mitochondrion organization GO:0007005 156 0.990
regulation of apoptotic signaling pathway GO:2001233 175 0.990
negative regulation by symbiont of host apoptotic process GO:0033668 1 0.988
Human
regulation of endopeptidase activity GO:0052548 170 0.987
modulation by organism of apoptotic process in other organism involved in symbiotic interaction GO:0052433 1 0.986
Human
modulation by symbiont of host cellular process GO:0044068 3 0.986
Human
modulation by symbiont of host programmed cell death GO:0052040 1 0.982
Human
mitochondrial transport GO:0006839 60 0.978
Human Mouse
regulation of peptidase activity GO:0052547 180 0.978
negative regulation of apoptotic process GO:0043066 316 0.978
Human Mouse
modulation by symbiont of host apoptotic process GO:0052150 1 0.977
Human
regulation of cysteine type endopeptidase activity GO:2000116 127 0.975
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 2 0.975
Mouse
regulation of cellular component biogenesis GO:0044087 281 0.973
response to virus GO:0009615 126 0.966
Human
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.966
Human
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.965
Human Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.960
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.960
Mouse
positive regulation of neuron apoptotic process GO:0043525 8 0.957
positive regulation of proteolysis GO:0045862 142 0.956
extrinsic apoptotic signaling pathway GO:0097191 119 0.953
positive regulation of endopeptidase activity GO:0010950 84 0.953
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.951
Human Mouse
modulation of apoptotic process in other organism GO:0044532 1 0.946
Human
positive regulation of cellular response to oxidative stress GO:1900409 7 0.943
Human
single organism membrane fusion GO:0044801 37 0.942
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.942
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903378 2 0.941
Human
apoptotic signaling pathway GO:0097190 268 0.938
lymphocyte apoptotic process GO:0070227 20 0.935
regulation of protein heterodimerization activity GO:0043497 5 0.933
regulation of mitochondrial membrane permeability GO:0046902 25 0.932
Human Mouse
regulation of membrane permeability GO:0090559 25 0.931
Human Mouse
apoptotic process involved in morphogenesis GO:0060561 3 0.924
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.923
Human
positive regulation of peptidase activity GO:0010952 88 0.916
negative regulation of anoikis GO:2000811 15 0.912
Human
positive regulation of protein homooligomerization GO:0032464 7 0.910
regulation of apoptotic dna fragmentation GO:1902510 3 0.907
positive regulation of cellular component biogenesis GO:0044089 158 0.904
modulation by virus of host process GO:0019054 2 0.904
Human
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.904
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.901
negative regulation of programmed cell death GO:0043069 321 0.897
Human Mouse
negative regulation of apoptotic signaling pathway GO:2001234 97 0.889
Human Mouse
signal transduction in absence of ligand GO:0038034 22 0.881
Human Mouse
protein processing GO:0016485 226 0.874
viral process GO:0016032 146 0.872
Human
intrinsic apoptotic signaling pathway GO:0097193 127 0.871
positive regulation of apoptotic process GO:0043065 246 0.871
positive regulation of execution phase of apoptosis GO:1900119 5 0.870
establishment of protein localization to mitochondrion GO:0072655 22 0.866
Mouse
regulation of oxidative stress induced cell death GO:1903201 24 0.864
Human
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 7 0.862
Human
positive regulation of fibroblast apoptotic process GO:2000271 6 0.857
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 2 0.853
regulation of proteolysis GO:0030162 293 0.852
modulation of programmed cell death in other organism GO:0044531 1 0.850
Human
negative regulation of cell death GO:0060548 345 0.850
Human Mouse
neuron intrinsic apoptotic signaling pathway in response to oxidative stress GO:0036480 7 0.849
Human
positive regulation of hydrolase activity GO:0051345 331 0.847
positive regulation of cell death GO:0010942 263 0.845
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.826
Mouse
positive regulation of organelle organization GO:0010638 195 0.823
activation of cysteine type endopeptidase activity GO:0097202 57 0.814
protein homooligomerization GO:0051260 100 0.809
endoplasmic reticulum unfolded protein response GO:0030968 16 0.806
modulation by virus of host apoptotic process GO:0039526 1 0.802
Human
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 16 0.800
Mouse
protein polyubiquitination GO:0000209 110 0.794
Human
regulation of cellular ph reduction GO:0032847 1 0.789
Human
mitochondrial fission GO:0000266 14 0.784
single organism membrane organization GO:0044802 268 0.781
cellular response to dna damage stimulus GO:0006974 379 0.779
Human Mouse
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.768
Human Mouse
protein maturation GO:0051604 233 0.765
regulation of response to dna damage stimulus GO:2001020 94 0.753
Human
response to organic cyclic compound GO:0014070 204 0.741
Human Rat
protein oligomerization GO:0051259 173 0.740
negative regulation of execution phase of apoptosis GO:1900118 6 0.727
Human
transformed cell apoptotic process GO:0006927 3 0.727
behavioral defense response GO:0002209 0 0.727
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.724
Human
multi organism cellular process GO:0044764 156 0.714
Human
membrane organization GO:0061024 292 0.714
monovalent inorganic cation homeostasis GO:0055067 37 0.707
Human
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.705
positive regulation of cellular component organization GO:0051130 376 0.705
zymogen activation GO:0031638 70 0.685
modification of morphology or physiology of other organism GO:0035821 43 0.676
Human
fear response GO:0042596 0 0.673
membrane fusion GO:0061025 43 0.672
retinal cell apoptotic process GO:1990009 1 0.662
er nucleus signaling pathway GO:0006984 23 0.649
signal transduction by p53 class mediator GO:0072331 72 0.647
Human Mouse
negative regulation of cell proliferation GO:0008285 228 0.646
Mouse
regulation of membrane potential GO:0042391 95 0.632
regulation of killing of cells of other organism GO:0051709 4 0.631
immune response activating signal transduction GO:0002757 90 0.618
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.605
interaction with host GO:0051701 42 0.601
Human
response to uv GO:0009411 73 0.593
Human Mouse
positive regulation of programmed cell death GO:0043068 249 0.582
post embryonic development GO:0009791 2 0.578
Mouse
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.570
Mouse
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.568
response to radiation GO:0009314 151 0.548
Human Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.543
Human
response to unfolded protein GO:0006986 24 0.534
protein localization to membrane GO:0072657 160 0.533
Human Mouse
b cell receptor signaling pathway GO:0050853 18 0.529
regulation of protein complex assembly GO:0043254 147 0.526
ion transmembrane transport GO:0034220 338 0.526
response to biotic stimulus GO:0009607 276 0.512
Human
antigen receptor mediated signaling pathway GO:0050851 38 0.509
cell type specific apoptotic process GO:0097285 125 0.497
single organism cellular localization GO:1902580 332 0.496
Human Mouse
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.495
Human
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 16 0.493
Mouse
anoikis GO:0043276 22 0.484
Human
positive regulation of dna metabolic process GO:0051054 73 0.484
establishment of protein localization to membrane GO:0090150 121 0.482
Human Mouse
response to alkaloid GO:0043279 20 0.476
Human Rat
positive regulation of neuron death GO:1901216 14 0.467
cell cycle phase transition GO:0044770 173 0.467
Human
organelle fusion GO:0048284 36 0.459
protein insertion into mitochondrial membrane GO:0051204 3 0.455
Mouse
cellular response to uv GO:0034644 32 0.450
Human Mouse
positive regulation of endoplasmic reticulum unfolded protein response GO:1900103 4 0.441
fibroblast apoptotic process GO:0044346 8 0.432
b cell apoptotic process GO:0001783 6 0.428
mitochondrial fusion GO:0008053 13 0.428
cell chemotaxis GO:0060326 112 0.427
cellular response to oxidative stress GO:0034599 85 0.423
Human
mitochondrial outer membrane permeabilization GO:0097345 15 0.423
Mouse
regulation of cell cycle process GO:0010564 266 0.420
Human
apoptotic dna fragmentation GO:0006309 6 0.415
neuron apoptotic process GO:0051402 39 0.415
regulation of cellular response to stress GO:0080135 244 0.412
cellular homeostasis GO:0019725 196 0.411
Human Mouse
cellular response to external stimulus GO:0071496 111 0.411
Human
regulation of endoplasmic reticulum unfolded protein response GO:1900101 5 0.406
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 2 0.389
taxis GO:0042330 157 0.387
positive regulation of leukocyte proliferation GO:0070665 48 0.385
Human
response to other organism GO:0051707 261 0.378
Human
modification by symbiont of host morphology or physiology GO:0044003 12 0.374
Human
mitotic cell cycle GO:0000278 326 0.372
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.359
cellular amine metabolic process GO:0044106 41 0.356
regulation of leukocyte proliferation GO:0070663 67 0.354
Human
dna catabolic process GO:0006308 49 0.353
developmental programmed cell death GO:0010623 3 0.349
Mouse
interspecies interaction between organisms GO:0044419 156 0.336
Human
mononuclear cell proliferation GO:0032943 71 0.336
Human Mouse
t cell apoptotic process GO:0070231 12 0.329
Mouse
metal ion transport GO:0030001 272 0.329
Human Mouse
positive regulation of protein complex assembly GO:0031334 86 0.324
negative regulation of response to dna damage stimulus GO:2001021 33 0.317
Human
negative regulation of cell cycle GO:0045786 193 0.317
Human
response to mechanical stimulus GO:0009612 51 0.315
Human
execution phase of apoptosis GO:0097194 32 0.312
protein ubiquitination GO:0016567 314 0.312
Human
regulation of mitochondrial fusion GO:0010635 5 0.305
leukocyte chemotaxis GO:0030595 76 0.302
positive regulation of oxidative stress induced neuron death GO:1903223 2 0.296
Human
response to abiotic stimulus GO:0009628 336 0.286
Human Mouse
cellular component disassembly involved in execution phase of apoptosis GO:0006921 13 0.284
regulation of cellular response to oxidative stress GO:1900407 26 0.280
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.278
positive regulation of transport GO:0051050 336 0.273
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.269
positive regulation of cellular catabolic process GO:0031331 284 0.269
protein modification by small protein conjugation GO:0032446 342 0.268
Human
response to electrical stimulus GO:0051602 1 0.264
dna catabolic process endonucleolytic GO:0000737 37 0.264
regulation of developmental pigmentation GO:0048070 2 0.261
Mouse
positive regulation of dna catabolic process GO:1903626 2 0.261
cellular response to endogenous stimulus GO:0071495 336 0.260
regulation of protein localization to plasma membrane GO:1903076 40 0.260
Human
regulation of neuron apoptotic process GO:0043523 35 0.260
ribonucleoside triphosphate metabolic process GO:0009199 412 0.257
negative regulation of cell cycle phase transition GO:1901988 89 0.256
Human
defense response to other organism GO:0098542 129 0.254
Human
response to steroid hormone GO:0048545 80 0.254
Rat
positive regulation of developmental pigmentation GO:0048087 2 0.254
Mouse
t cell homeostasis GO:0043029 3 0.251
Mouse
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.245
regulation of protein homooligomerization GO:0032462 11 0.243
positive regulation of immune system process GO:0002684 283 0.241
regulation of establishment of protein localization GO:0070201 242 0.241
Human
guanosine containing compound catabolic process GO:1901069 239 0.236
negative regulation of catalytic activity GO:0043086 335 0.236
response to external biotic stimulus GO:0043207 261 0.235
Human
growth GO:0040007 202 0.234
Human
protein catabolic process GO:0030163 325 0.231
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901028 9 0.230
regeneration GO:0031099 4 0.229
cellular response to topologically incorrect protein GO:0035967 19 0.227
response to hydrogen peroxide GO:0042542 40 0.226
glycosyl compound catabolic process GO:1901658 413 0.221
hematopoietic or lymphoid organ development GO:0048534 186 0.221
Mouse
cellular response to light stimulus GO:0071482 34 0.210
Human Mouse
response to oxidative stress GO:0006979 121 0.209
Human
lymphocyte homeostasis GO:0002260 4 0.207
Mouse
cellular response to abiotic stimulus GO:0071214 117 0.207
Human Mouse
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 20 0.203
Human
mitochondrial fragmentation involved in apoptotic process GO:0043653 7 0.200
cell death in response to oxidative stress GO:0036473 29 0.200
Human
negative regulation of calcium ion transport into cytosol GO:0010523 3 0.198
cellular ion homeostasis GO:0006873 168 0.197
Human Mouse
activation of immune response GO:0002253 114 0.196
regulation of transporter activity GO:0032409 82 0.195
Human
mitotic cell cycle phase transition GO:0044772 162 0.195
Human
negative regulation of binding GO:0051100 57 0.195
leukocyte apoptotic process GO:0071887 31 0.192
positive regulation of lymphocyte proliferation GO:0050671 46 0.190
Human
cellular response to unfolded protein GO:0034620 16 0.189
response to endoplasmic reticulum stress GO:0034976 49 0.185
epidermis morphogenesis GO:0048730 3 0.184
cellular response to mechanical stimulus GO:0071260 39 0.184
Human
cellular calcium ion homeostasis GO:0006874 117 0.183
Mouse
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 38 0.182
Human
apoptotic process in bone marrow GO:0071839 1 0.182
epithelial cell proliferation GO:0050673 128 0.182
Mouse
b cell homeostasis GO:0001782 1 0.179
Mouse
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.179
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.178
Human Mouse
response to hormone GO:0009725 175 0.175
Rat
response to topologically incorrect protein GO:0035966 29 0.172
purine nucleoside catabolic process GO:0006152 398 0.170
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.169
positive regulation of b cell activation GO:0050871 17 0.168
Human
defense response to virus GO:0051607 71 0.165
Human
pigment granule organization GO:0048753 7 0.164
amine metabolic process GO:0009308 44 0.164
negative regulation of cellular component organization GO:0051129 235 0.162
Human
negative regulation of organelle organization GO:0010639 126 0.162
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.158
regulation of cellular amino acid metabolic process GO:0006521 6 0.154
regulation of growth GO:0040008 165 0.151
Human
calcium ion transport GO:0006816 147 0.150
Human Mouse
lymphocyte activation GO:0046649 133 0.149
Human Mouse
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.149
positive regulation of immune response GO:0050778 159 0.149
purine ribonucleoside metabolic process GO:0046128 437 0.149
regulation of ubiquitin protein transferase activity GO:0051438 28 0.144
regulation of protein localization GO:0032880 296 0.144
Human
pancreas development GO:0031016 19 0.143
regulation of cellular amine metabolic process GO:0033238 11 0.141
ribonucleoside triphosphate catabolic process GO:0009203 391 0.140
neuron death GO:0070997 65 0.139
regulation of mitotic cell cycle phase transition GO:1901990 118 0.136
Human
cation transport GO:0006812 331 0.136
Human Mouse
negative regulation of protein binding GO:0032091 35 0.136
response to alcohol GO:0097305 64 0.134
Rat
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.134
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.132
establishment of protein localization to plasma membrane GO:0090002 68 0.131
Human
post embryonic organ development GO:0048569 1 0.130
Mouse
regulation of nucleoside metabolic process GO:0009118 209 0.129
male sex differentiation GO:0046661 25 0.129
Mouse
chemotaxis GO:0006935 157 0.129
endocrine pancreas development GO:0031018 11 0.128
killing of cells in other organism involved in symbiotic interaction GO:0051883 3 0.125
hair follicle morphogenesis GO:0031069 2 0.125
nucleoside catabolic process GO:0009164 408 0.124
immune effector process GO:0002252 159 0.122
Human
negative regulation of cell cycle process GO:0010948 121 0.122
Human
apoptotic nuclear changes GO:0030262 13 0.121
thymus development GO:0048538 3 0.120
disruption of cells of other organism involved in symbiotic interaction GO:0051818 3 0.120
negative regulation of intracellular signal transduction GO:1902532 183 0.118
Human
regulation of anoikis GO:2000209 19 0.118
Human
cytokinesis GO:0000910 96 0.117
Human
protein targeting to mitochondrion GO:0006626 19 0.116
regulation of epithelial cell proliferation GO:0050678 113 0.115
Mouse
immune response GO:0006955 307 0.114
cellular cation homeostasis GO:0030003 163 0.113
Human Mouse
positive regulation of b cell proliferation GO:0030890 12 0.113
Human
regulation of cell cycle GO:0051726 393 0.112
Human Mouse
embryonic digit morphogenesis GO:0042733 6 0.111
Mouse
response to inorganic substance GO:0010035 127 0.111
Human Zebrafish Rat
intracellular protein transport GO:0006886 270 0.109
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.109
cellular response to organic cyclic compound GO:0071407 127 0.105
positive regulation of transferase activity GO:0051347 227 0.105
organelle fission GO:0048285 149 0.104
negative regulation of establishment of protein localization to plasma membrane GO:0090005 9 0.102
Human
regulation of fibroblast apoptotic process GO:2000269 8 0.101
endomembrane system organization GO:0010256 196 0.100
Human
regulation of mitochondrial membrane potential GO:0051881 23 0.098
regulation of response to oxidative stress GO:1902882 26 0.095
Human
immune response regulating signaling pathway GO:0002764 97 0.095
modification dependent protein catabolic process GO:0019941 209 0.095
negative regulation of protein metabolic process GO:0051248 391 0.092
Mouse
cellular response to hypoxia GO:0071456 51 0.090
endoplasmic reticulum calcium ion homeostasis GO:0032469 9 0.089
Mouse
gtp metabolic process GO:0046039 239 0.089
positive regulation of killing of cells of other organism GO:0051712 4 0.089
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.086
cellular response to radiation GO:0071478 65 0.086
Human Mouse
cell division GO:0051301 168 0.086
Human
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.084
purine nucleoside triphosphate catabolic process GO:0009146 392 0.084
divalent metal ion transport GO:0070838 152 0.083
Human Mouse
response to light stimulus GO:0009416 87 0.080
Human Mouse
guanosine containing compound metabolic process GO:1901068 244 0.079
response to cycloheximide GO:0046898 1 0.077
regulation of neuron death GO:1901214 56 0.077
cytoplasmic transport GO:0016482 379 0.077
Mouse
regulation of mitotic cell cycle GO:0007346 189 0.076
Human
positive regulation of cell proliferation GO:0008284 301 0.076
Human
renal system development GO:0072001 63 0.076
Mouse
glial cell apoptotic process GO:0034349 7 0.075
Rat
purine ribonucleotide catabolic process GO:0009154 404 0.074
regulation of interferon beta biosynthetic process GO:0045357 4 0.074
leukocyte migration GO:0050900 107 0.073
small gtpase mediated signal transduction GO:0007264 78 0.072
ras protein signal transduction GO:0007265 73 0.072
ribonucleotide catabolic process GO:0009261 405 0.070
regulation of protein kinase activity GO:0045859 289 0.070
cellular component morphogenesis GO:0032989 314 0.070
Mouse
negative regulation of neuron apoptotic process GO:0043524 23 0.070
Human Mouse
regulation of establishment of protein localization to plasma membrane GO:0090003 30 0.070
Human
nervous system development GO:0007399 293 0.070
Mouse Rat
protein targeting GO:0006605 187 0.069
aging GO:0007568 66 0.069
cytokine mediated signaling pathway GO:0019221 109 0.068
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.067
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.066
Human
response to organonitrogen compound GO:0010243 156 0.065
Human Rat
regulation of purine nucleotide metabolic process GO:1900542 264 0.065
negative regulation of cellular protein metabolic process GO:0032269 353 0.064
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.064
odontogenesis GO:0042476 25 0.064
Mouse
mitotic cell cycle checkpoint GO:0007093 68 0.063
Human
regulation of dna catabolic process GO:1903624 7 0.063
cellular chemical homeostasis GO:0055082 180 0.062
Human Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.062
regulation of lymphocyte proliferation GO:0050670 64 0.061
Human
divalent inorganic cation transport GO:0072511 158 0.061
Human Mouse
cellular protein catabolic process GO:0044257 261 0.060
cellular response to glucocorticoid stimulus GO:0071385 4 0.059
response to toxic substance GO:0009636 37 0.059
negative regulation of proteolysis GO:0045861 132 0.058
endocrine system development GO:0035270 26 0.058
regulation of dna metabolic process GO:0051052 153 0.058
multicellular organismal aging GO:0010259 3 0.057
embryonic appendage morphogenesis GO:0035113 9 0.057
Mouse
regulation of binding GO:0051098 111 0.057
regulation of b cell proliferation GO:0030888 18 0.056
Human
regulation of transferase activity GO:0051338 355 0.056
regulation of homeostatic process GO:0032844 121 0.056
Human Mouse
cellular response to oxygen containing compound GO:1901701 276 0.056
protein localization to organelle GO:0033365 280 0.056
Mouse
urogenital system development GO:0001655 65 0.056
Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.055
cell cycle checkpoint GO:0000075 117 0.055
Human
regulation of lymphocyte activation GO:0051249 103 0.055
Human
cytokine production GO:0001816 247 0.054
negative regulation of mitotic cell cycle GO:0045930 102 0.053
Human
tube morphogenesis GO:0035239 95 0.053
Mouse
plasma membrane organization GO:0007009 115 0.053
Human
cell killing GO:0001906 34 0.053
negative regulation of hydrolase activity GO:0051346 182 0.053
regulation of transmembrane transport GO:0034762 139 0.052
Human
regulation of cell cycle phase transition GO:1901987 126 0.052
Human
metal ion homeostasis GO:0055065 169 0.052
Mouse
defense response GO:0006952 315 0.051
Human
positive regulation of nucleoside metabolic process GO:0045979 186 0.051
regulation of protein binding GO:0043393 66 0.051
gtp catabolic process GO:0006184 237 0.051
cellular protein complex assembly GO:0043623 188 0.050
response to transition metal nanoparticle GO:1990267 29 0.050
Human Zebrafish Rat
determination of adult lifespan GO:0008340 2 0.050
transmembrane transport GO:0055085 399 0.049
regulation of protein stability GO:0031647 87 0.048
positive regulation of cytokine production GO:0001819 167 0.048
positive regulation of phosphorylation GO:0042327 394 0.047
cell substrate adhesion GO:0031589 132 0.047
purine containing compound catabolic process GO:0072523 411 0.047
development of primary male sexual characteristics GO:0046546 23 0.047
Mouse
response to nitrogen compound GO:1901698 184 0.046
Human Rat
regulation of cell migration GO:0030334 289 0.046
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.046
purine nucleotide catabolic process GO:0006195 405 0.046
biological adhesion GO:0022610 331 0.046
negative regulation of phosphorus metabolic process GO:0010563 267 0.045
Mouse
negative regulation of protein localization to plasma membrane GO:1903077 13 0.045
Human
regulation of calcium ion transport GO:0051924 79 0.045
Human Mouse
protein localization to mitochondrion GO:0070585 25 0.044
Mouse
secretion by cell GO:0032940 226 0.044
positive regulation of catabolic process GO:0009896 310 0.044
leukocyte homeostasis GO:0001776 7 0.044
Mouse
cellular metal ion homeostasis GO:0006875 146 0.044
Mouse
male gonad development GO:0008584 23 0.044
Mouse
organophosphate catabolic process GO:0046434 430 0.044
response to oxygen containing compound GO:1901700 369 0.043
Rat
regulation of purine nucleotide catabolic process GO:0033121 205 0.043
ossification GO:0001503 121 0.043
negative regulation of transferase activity GO:0051348 124 0.043
peptidyl serine modification GO:0018209 106 0.042
Mouse
cellular ketone metabolic process GO:0042180 80 0.042
multicellular organismal response to stress GO:0033555 1 0.042
negative regulation of cell growth GO:0030308 83 0.041
secretion GO:0046903 254 0.041
enzyme linked receptor protein signaling pathway GO:0007167 303 0.041
cellular macromolecular complex assembly GO:0034622 324 0.040
cellular response to decreased oxygen levels GO:0036294 51 0.040
positive regulation of lymphocyte activation GO:0051251 73 0.040
Human
regulation of cell growth GO:0001558 135 0.040
Human
reactive oxygen species metabolic process GO:0072593 75 0.040
regulation of response to external stimulus GO:0032101 222 0.039
positive regulation of cellular amine metabolic process GO:0033240 7 0.039
cellular response to organonitrogen compound GO:0071417 124 0.039
compound eye development GO:0048749 1 0.038
cellular amino acid metabolic process GO:0006520 116 0.038
response to hypoxia GO:0001666 96 0.038
b cell activation GO:0042113 33 0.037
Human Mouse
positive regulation of growth GO:0045927 58 0.037
Human
purine ribonucleoside catabolic process GO:0046130 398 0.037
ribonucleoside catabolic process GO:0042454 406 0.037
cellular response to extracellular stimulus GO:0031668 72 0.037
lymphocyte proliferation GO:0046651 70 0.037
Human Mouse
regulation of transmembrane transporter activity GO:0022898 74 0.036
Human
ubiquitin dependent protein catabolic process GO:0006511 206 0.036
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 1 0.035
positive regulation of ligase activity GO:0051351 19 0.035
positive regulation of secretion GO:0051047 116 0.035
nucleoside phosphate catabolic process GO:1901292 412 0.035
regulation of multi organism process GO:0043900 157 0.035
cellular response to glucose starvation GO:0042149 8 0.035
regulation of cytoskeleton organization GO:0051493 177 0.035
positive regulation of cell activation GO:0050867 81 0.035
Human
response to reactive oxygen species GO:0000302 61 0.034
cellular component disassembly GO:0022411 92 0.034
homeostasis of number of cells GO:0048872 40 0.034
Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.034
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.034
regulation of protein maturation GO:1903317 150 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.033
developmental growth GO:0048589 48 0.033
regulation of protein ubiquitination GO:0031396 95 0.033
protein secretion GO:0009306 98 0.033
regulation of gtp catabolic process GO:0033124 180 0.033
establishment of protein localization to organelle GO:0072594 172 0.032
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.032
regulation of immune response GO:0050776 201 0.031
response to iron ion GO:0010039 6 0.031
Human
protein localization to plasma membrane GO:0072659 93 0.030
Human
sensory organ development GO:0007423 52 0.030
Mouse
regulation of mitosis GO:0007088 63 0.030
regulation of ion transport GO:0043269 189 0.030
Human Mouse
negative regulation of interferon beta production GO:0032688 4 0.030
epithelium development GO:0060429 227 0.029
Mouse
cellular response to virus GO:0098586 9 0.029
organ growth GO:0035265 12 0.029
regulation of cellular component movement GO:0051270 334 0.029
mitotic nuclear division GO:0007067 119 0.029
embryo development GO:0009790 123 0.029
Mouse
extracellular negative regulation of signal transduction GO:1900116 9 0.028
positive regulation of pigment cell differentiation GO:0050942 2 0.028
hindbrain development GO:0030902 3 0.028
spleen development GO:0048536 1 0.028
cell part morphogenesis GO:0032990 137 0.028
Mouse
sequestering of calcium ion GO:0051208 17 0.028
embryonic limb morphogenesis GO:0030326 9 0.028
Mouse
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.028

BAX disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.062
gastrointestinal system cancer DOID:3119 52 0.035
cancer DOID:162 167 0.035
organ system cancer DOID:0050686 164 0.035
disease of metabolism DOID:0014667 295 0.030