Homo sapiens

0 known processes

RDH8

retinol dehydrogenase 8 (all-trans)

(Aliases: PRRDH,SDR28C2)

RDH8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
mapk cascade GO:0000165 288 0.086
amine metabolic process GO:0009308 44 0.078
ion homeostasis GO:0050801 230 0.076
cation transport GO:0006812 331 0.072
positive regulation of phosphorylation GO:0042327 394 0.066
cellular amine metabolic process GO:0044106 41 0.065
g protein coupled receptor signaling pathway GO:0007186 207 0.064
chemical homeostasis GO:0048878 306 0.062
regulation of cytokine production GO:0001817 232 0.060
regulation of cellular ketone metabolic process GO:0010565 50 0.057
regulation of cellular amino acid metabolic process GO:0006521 6 0.055
cellular cation homeostasis GO:0030003 163 0.054
ion transmembrane transport GO:0034220 338 0.052
immune response GO:0006955 307 0.050
transmembrane transport GO:0055085 399 0.050
biological adhesion GO:0022610 331 0.049
regulation of cellular component movement GO:0051270 334 0.047
cellular ketone metabolic process GO:0042180 80 0.046
cytokine production GO:0001816 247 0.045
regulation of cellular amine metabolic process GO:0033238 11 0.045
cell activation GO:0001775 213 0.045
system process GO:0003008 349 0.045
regulation of mapk cascade GO:0043408 262 0.044
positive regulation of cell proliferation GO:0008284 301 0.043
cell adhesion GO:0007155 325 0.042
cellular amino acid metabolic process GO:0006520 116 0.041
positive regulation of transport GO:0051050 336 0.041
positive regulation of cellular component organization GO:0051130 376 0.041
signal transduction by phosphorylation GO:0023014 297 0.040
defense response GO:0006952 315 0.040
positive regulation of protein phosphorylation GO:0001934 313 0.039
post embryonic development GO:0009791 2 0.039
metal ion transport GO:0030001 272 0.037
positive regulation of cellular amine metabolic process GO:0033240 7 0.037
cellular ion homeostasis GO:0006873 168 0.037
metal ion homeostasis GO:0055065 169 0.037
cellular homeostasis GO:0019725 196 0.037
anatomical structure formation involved in morphogenesis GO:0048646 284 0.035
cellular chemical homeostasis GO:0055082 180 0.035
regulation of cell differentiation GO:0045595 393 0.035
anion transport GO:0006820 161 0.034
positive regulation of protein kinase activity GO:0045860 190 0.034
lipid metabolic process GO:0006629 381 0.034
negative regulation of apoptotic process GO:0043066 316 0.033
response to other organism GO:0051707 261 0.033
regulation of transferase activity GO:0051338 355 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
vesicle mediated transport GO:0016192 371 0.032
cellular divalent inorganic cation homeostasis GO:0072503 128 0.032
membrane organization GO:0061024 292 0.031
secretion by cell GO:0032940 226 0.031
cellular component morphogenesis GO:0032989 314 0.031
cardiovascular system development GO:0072358 262 0.031
negative regulation of programmed cell death GO:0043069 321 0.031
negative regulation of cell death GO:0060548 345 0.030
circulatory system development GO:0072359 262 0.030
vasculature development GO:0001944 181 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
regulation of protein kinase activity GO:0045859 289 0.029
regulation of cell motility GO:2000145 299 0.029
nitrogen compound transport GO:0071705 191 0.029
regulation of cell activation GO:0050865 125 0.029
regulation of protein localization GO:0032880 296 0.029
positive regulation of mapk cascade GO:0043410 190 0.029
cation homeostasis GO:0055080 189 0.029
response to external biotic stimulus GO:0043207 261 0.028
secretion GO:0046903 254 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
neuromuscular junction development GO:0007528 3 0.026
response to biotic stimulus GO:0009607 276 0.026
blood vessel development GO:0001568 172 0.026
regulation of proteolysis GO:0030162 293 0.026
divalent metal ion transport GO:0070838 152 0.026
calcium ion homeostasis GO:0055074 122 0.025
neurological system process GO:0050877 163 0.025
striated muscle contraction GO:0006941 52 0.025
protein maturation GO:0051604 233 0.025
regulation of cellular component biogenesis GO:0044087 281 0.025
blood vessel morphogenesis GO:0048514 162 0.025
regulation of ion transport GO:0043269 189 0.025
female gamete generation GO:0007292 2 0.024
protein processing GO:0016485 226 0.024
negative regulation of transport GO:0051051 176 0.024
regulation of kinase activity GO:0043549 314 0.024
muscle contraction GO:0006936 73 0.024
cell morphogenesis GO:0000902 296 0.024
enzyme linked receptor protein signaling pathway GO:0007167 303 0.024
cellular macromolecule catabolic process GO:0044265 380 0.023
single organism membrane organization GO:0044802 268 0.023
protein catabolic process GO:0030163 325 0.023
positive regulation of cytokine production GO:0001819 167 0.023
positive regulation of cell motility GO:2000147 177 0.023
regulation of response to external stimulus GO:0032101 222 0.023
determination of adult lifespan GO:0008340 2 0.023
multicellular organismal aging GO:0010259 3 0.023
innate immune response GO:0045087 178 0.023
positive regulation of kinase activity GO:0033674 204 0.023
negative regulation of multicellular organismal process GO:0051241 317 0.022
response to oxygen containing compound GO:1901700 369 0.022
cardiac muscle cell contraction GO:0086003 4 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
regulation of homeostatic process GO:0032844 121 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
positive regulation of transferase activity GO:0051347 227 0.022
regulation of cell cycle GO:0051726 393 0.022
organic anion transport GO:0015711 103 0.022
regulation of transmembrane transport GO:0034762 139 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
epithelium development GO:0060429 227 0.021
regulation of leukocyte activation GO:0002694 115 0.021
angiogenesis GO:0001525 147 0.021
regulation of secretion by cell GO:1903530 177 0.021
regulation of secretion GO:0051046 194 0.021
negative regulation of cytokine production GO:0001818 82 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
purine containing compound catabolic process GO:0072523 411 0.021
response to organic cyclic compound GO:0014070 204 0.021
cellular metal ion homeostasis GO:0006875 146 0.020
cytoplasmic transport GO:0016482 379 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
cell development GO:0048468 328 0.020
regulation of protein transport GO:0051223 213 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
positive regulation of cellular component movement GO:0051272 181 0.020
mitotic cell cycle GO:0000278 326 0.020
leukocyte activation GO:0045321 164 0.020
regulation of protein serine threonine kinase activity GO:0071900 179 0.020
calcium ion transport GO:0006816 147 0.020
regulation of endopeptidase activity GO:0052548 170 0.019
synaptic transmission involved in micturition GO:0060084 2 0.019
actin filament based process GO:0030029 224 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
regulation of dna metabolic process GO:0051052 153 0.019
single organism cellular localization GO:1902580 332 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
peptidyl tyrosine modification GO:0018212 170 0.019
oogenesis GO:0048477 2 0.019
mitotic cell cycle process GO:1903047 286 0.019
regulation of locomotion GO:0040012 329 0.019
cation transmembrane transport GO:0098655 238 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
positive regulation of locomotion GO:0040017 186 0.018
regulation of cell migration GO:0030334 289 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
maintenance of location GO:0051235 112 0.018
protein oligomerization GO:0051259 173 0.018
cellular lipid metabolic process GO:0044255 303 0.018
regulation of cell adhesion GO:0030155 166 0.018
organophosphate catabolic process GO:0046434 430 0.018
nervous system development GO:0007399 293 0.018
divalent inorganic cation transport GO:0072511 158 0.018
segmentation GO:0035282 4 0.018
protein localization to membrane GO:0072657 160 0.018
cellular protein catabolic process GO:0044257 261 0.017
erk1 and erk2 cascade GO:0070371 104 0.017
response to growth factor GO:0070848 205 0.017
divalent inorganic cation homeostasis GO:0072507 136 0.017
ras protein signal transduction GO:0007265 73 0.017
sequestering of calcium ion GO:0051208 17 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
memory GO:0007613 3 0.017
response to abiotic stimulus GO:0009628 336 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.016
rho protein signal transduction GO:0007266 26 0.016
regulation of cellular response to stress GO:0080135 244 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
positive regulation of cell migration GO:0030335 172 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
actin mediated cell contraction GO:0070252 12 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
nucleoside catabolic process GO:0009164 408 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
regulation of cell cycle process GO:0010564 266 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
peptidyl tyrosine phosphorylation GO:0018108 170 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.016
positive regulation of immune system process GO:0002684 283 0.016
regulation of acetylcholine gated cation channel activity GO:1903048 1 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
response to nitrogen compound GO:1901698 184 0.015
cell projection organization GO:0030030 252 0.015
sequestering of metal ion GO:0051238 24 0.015
postsynaptic membrane organization GO:0001941 2 0.015
single organism cell adhesion GO:0098602 179 0.015
hindbrain development GO:0030902 3 0.015
cell cell signaling GO:0007267 155 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
regulation of transmembrane transporter activity GO:0022898 74 0.015
regulation of erk1 and erk2 cascade GO:0070372 99 0.015
negative regulation of developmental process GO:0051093 247 0.015
immune system development GO:0002520 195 0.015
regulation of transporter activity GO:0032409 82 0.015
locomotory behavior GO:0007626 1 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
visual behavior GO:0007632 2 0.015
regulation of multi organism process GO:0043900 157 0.015
purine nucleoside catabolic process GO:0006152 398 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
actin filament based movement GO:0030048 17 0.014
regulation of ion transmembrane transport GO:0034765 132 0.014
dna repair GO:0006281 198 0.014
protein localization to organelle GO:0033365 280 0.014
apoptotic signaling pathway GO:0097190 268 0.014
taxis GO:0042330 157 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
regulation of immune response GO:0050776 201 0.014
cellular calcium ion homeostasis GO:0006874 117 0.014
response to inorganic substance GO:0010035 127 0.014
immune effector process GO:0002252 159 0.014
sensory perception GO:0007600 103 0.014
muscle system process GO:0003012 81 0.014
response to radiation GO:0009314 151 0.014
organelle assembly GO:0070925 176 0.014
positive regulation of catabolic process GO:0009896 310 0.014
regeneration GO:0031099 4 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
activation of protein kinase activity GO:0032147 90 0.014
associative learning GO:0008306 1 0.014
response to wounding GO:0009611 168 0.014
chemotaxis GO:0006935 157 0.014
regulation of response to wounding GO:1903034 101 0.014
regulation of map kinase activity GO:0043405 108 0.014
chromatin organization GO:0006325 351 0.014
carbohydrate metabolic process GO:0005975 207 0.014
negative regulation of acetylcholine gated cation channel activity GO:1903049 1 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
micturition GO:0060073 3 0.014
nucleotide catabolic process GO:0009166 408 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
organic acid transport GO:0015849 65 0.013
positive regulation of cell adhesion GO:0045785 84 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
regulation of protein processing GO:0070613 150 0.013
central nervous system development GO:0007417 123 0.013
regulation of lymphocyte activation GO:0051249 103 0.013
neurogenesis GO:0022008 169 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
response to bacterium GO:0009617 144 0.013
hemopoiesis GO:0030097 180 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
positive regulation of developmental process GO:0051094 314 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
regulation of intracellular transport GO:0032386 195 0.013
anatomical structure homeostasis GO:0060249 100 0.013
cytosolic calcium ion homeostasis GO:0051480 89 0.013
blastoderm segmentation GO:0007350 2 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
regulation of protein catabolic process GO:0042176 155 0.013
wound healing GO:0042060 115 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.013
small molecule biosynthetic process GO:0044283 157 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
organ morphogenesis GO:0009887 147 0.013
cell matrix adhesion GO:0007160 85 0.013
negative regulation of protein processing GO:0010955 142 0.013
regulation of angiogenesis GO:0045765 92 0.013
cell division GO:0051301 168 0.012
positive regulation of ion transport GO:0043270 87 0.012
regulation of peptidase activity GO:0052547 180 0.012
anterior posterior axis specification GO:0009948 2 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
dna replication GO:0006260 116 0.012
protein targeting GO:0006605 187 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
glycoprotein metabolic process GO:0009100 110 0.012
positive regulation of organelle organization GO:0010638 195 0.012
regulation of hormone levels GO:0010817 125 0.012
interspecies interaction between organisms GO:0044419 156 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
epithelial cell proliferation GO:0050673 128 0.012
intracellular protein transport GO:0006886 270 0.012
single organismal cell cell adhesion GO:0016337 148 0.012
cardiac muscle contraction GO:0060048 34 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
muscle structure development GO:0061061 98 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
lipid biosynthetic process GO:0008610 177 0.012
response to metal ion GO:0010038 84 0.012
lymphocyte activation GO:0046649 133 0.012
regulation of protein maturation GO:1903317 150 0.012
negative regulation of protein modification process GO:0031400 200 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
blood circulation GO:0008015 113 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
negative regulation of protein maturation GO:1903318 142 0.012
alcohol metabolic process GO:0006066 114 0.011
negative regulation of ion transport GO:0043271 39 0.011
oocyte development GO:0048599 1 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
negative regulation of immune system process GO:0002683 136 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
response to virus GO:0009615 126 0.011
regulation of defense response GO:0031347 154 0.011
tissue migration GO:0090130 119 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
growth GO:0040007 202 0.011
regulation of metal ion transport GO:0010959 120 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
positive regulation of proteolysis GO:0045862 142 0.011
negative regulation of proteolysis GO:0045861 132 0.011
spermatid differentiation GO:0048515 4 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
cell cycle phase transition GO:0044770 173 0.011
leukocyte migration GO:0050900 107 0.011
oxidation reduction process GO:0055114 396 0.011
response to cytokine GO:0034097 232 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
multi organism cellular process GO:0044764 156 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
positive regulation of lymphocyte activation GO:0051251 73 0.011
response to light stimulus GO:0009416 87 0.011
regulation of ion homeostasis GO:2000021 73 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
carboxylic acid transport GO:0046942 63 0.011
epithelium migration GO:0090132 119 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
regulation of protein complex assembly GO:0043254 147 0.011
viral process GO:0016032 146 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
oocyte differentiation GO:0009994 2 0.010
response to lipid GO:0033993 206 0.010
chromatin modification GO:0016568 298 0.010
av node cell to bundle of his cell communication GO:0086067 4 0.010
microtubule based process GO:0007017 210 0.010
metencephalon development GO:0022037 2 0.010
protein import GO:0017038 130 0.010
wnt signaling pathway GO:0016055 156 0.010
positive regulation of leukocyte activation GO:0002696 80 0.010
atp metabolic process GO:0046034 176 0.010
regulation of purine nucleotide metabolic process GO:1900542 264 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
ribonucleoside monophosphate metabolic process GO:0009161 187 0.010
epidermis morphogenesis GO:0048730 3 0.010

RDH8 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.049
nervous system disease DOID:863 431 0.049
disease of metabolism DOID:0014667 295 0.035
eye and adnexa disease DOID:1492 150 0.029
eye disease DOID:5614 149 0.029
retinal disease DOID:5679 118 0.020
musculoskeletal system disease DOID:17 223 0.016
night blindness DOID:8499 10 0.013
congenital stationary night blindness DOID:0050534 8 0.013
retinal degeneration DOID:8466 89 0.012