Homo sapiens

160 known processes

HDAC4

histone deacetylase 4

(Aliases: KIAA0288,HD4,HDAC-A,HDACA,BDMR,HA6116,AHO3)

HDAC4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to parathyroid hormone stimulus GO:0071374 2 1.000
Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.997
regulation of cardiac muscle cell differentiation GO:2000725 7 0.997
positive regulation of skeletal muscle cell differentiation GO:2001016 1 0.995
positive regulation of myoblast differentiation GO:0045663 6 0.994
midgut development GO:0007494 1 0.994
positive regulation of dna templated transcription elongation GO:0032786 18 0.992
locomotory behavior GO:0007626 1 0.986
skeletal muscle fiber development GO:0048741 12 0.976
Mouse
positive regulation of cardiac muscle cell differentiation GO:2000727 4 0.974
neuron differentiation GO:0030182 138 0.970
Worm
response to parathyroid hormone GO:0071107 3 0.967
Rat
regulation of muscle cell differentiation GO:0051147 31 0.966
regulation of striated muscle cell differentiation GO:0051153 25 0.959
cellular response to abiotic stimulus GO:0071214 117 0.958
Rat
regulation of myotube differentiation GO:0010830 18 0.957
cell fate determination GO:0001709 3 0.948
cellular response to calcium ion GO:0071277 19 0.932
circadian behavior GO:0048512 2 0.927
positive regulation of developmental process GO:0051094 314 0.926
Human
regulation of muscle organ development GO:0048634 27 0.926
Mouse
cell development GO:0048468 328 0.924
Zebrafish Mouse Worm
response to abiotic stimulus GO:0009628 336 0.919
Rat
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.914
secondary heart field specification GO:0003139 2 0.906
rhythmic behavior GO:0007622 2 0.896
cardiac chamber formation GO:0003207 2 0.894
regulation of ossification GO:0030278 58 0.894
Human Mouse
negative regulation of myotube differentiation GO:0010832 4 0.891
regulation of cell differentiation GO:0045595 393 0.887
regulation of synaptic plasticity GO:0048167 3 0.885
regulation of skeletal muscle fiber development GO:0048742 12 0.877
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.855
Human Mouse
lipid localization GO:0010876 106 0.855
negative regulation of striated muscle cell differentiation GO:0051154 8 0.854
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.837
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.836
response to calcium ion GO:0051592 46 0.823
organ formation GO:0048645 3 0.819
regulation of striated muscle tissue development GO:0016202 26 0.801
Mouse
regulation of cell development GO:0060284 161 0.793
Zebrafish Mouse Worm
muscle hypertrophy in response to stress GO:0003299 4 0.793
regulation of skeletal muscle cell differentiation GO:2001014 3 0.792
positive regulation of muscle cell differentiation GO:0051149 15 0.781
nervous system development GO:0007399 293 0.775
Worm
positive regulation of striated muscle cell differentiation GO:0051155 9 0.772
adult heart development GO:0007512 6 0.771
behavior GO:0007610 112 0.763
Fly
mitochondrion organization GO:0007005 156 0.762
myotube cell development GO:0014904 14 0.755
Mouse
myotube differentiation GO:0014902 22 0.755
regulation of cardiac muscle cell proliferation GO:0060043 4 0.751
response to virus GO:0009615 126 0.744
regulation of neurogenesis GO:0050767 82 0.738
Worm
regulation of neuron differentiation GO:0045664 70 0.738
Worm
heart formation GO:0060914 2 0.722
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.702
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.700
maintenance of location GO:0051235 112 0.697
blood circulation GO:0008015 113 0.696
Mouse
cardiac ventricle formation GO:0003211 2 0.694
regulation of nervous system development GO:0051960 88 0.694
Worm
regulation of myoblast differentiation GO:0045661 12 0.680
covalent chromatin modification GO:0016569 254 0.677
cellular response to inorganic substance GO:0071241 45 0.670
positive regulation of cell differentiation GO:0045597 211 0.664
signal transduction by phosphorylation GO:0023014 297 0.647
ion transmembrane transport GO:0034220 338 0.634
cell morphogenesis involved in differentiation GO:0000904 144 0.633
Zebrafish
regulation of heart growth GO:0060420 4 0.622
mitochondrion distribution GO:0048311 3 0.621
cellular response to hormone stimulus GO:0032870 125 0.618
Human Rat
nephron tubule epithelial cell differentiation GO:0072160 3 0.613
cardiac muscle tissue development GO:0048738 39 0.612
behavioral defense response GO:0002209 0 0.600
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.591
mapk cascade GO:0000165 288 0.588
ventricular cardiac muscle cell differentiation GO:0055012 1 0.583
cellular response to metal ion GO:0071248 43 0.581
cellular response to fluid shear stress GO:0071498 7 0.579
positive regulation of protein sumoylation GO:0033235 7 0.573
regulation of membrane potential GO:0042391 95 0.570
cellular component morphogenesis GO:0032989 314 0.564
Zebrafish
peptidyl lysine modification GO:0018205 144 0.564
growth GO:0040007 202 0.562
Worm
epithelial cell differentiation GO:0030855 141 0.559
regulation of binding GO:0051098 111 0.558
cellular response to endogenous stimulus GO:0071495 336 0.557
Human Rat
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.555
actin filament based process GO:0030029 224 0.548
organelle assembly GO:0070925 176 0.545
humoral immune response GO:0006959 49 0.544
heart development GO:0007507 95 0.530
chromatin organization GO:0006325 351 0.517
regulation of neurotransmitter secretion GO:0046928 3 0.517
regulation of dna templated transcription in response to stress GO:0043620 18 0.513
myoblast differentiation GO:0045445 21 0.508
positive regulation of muscle organ development GO:0048636 7 0.507
positive regulation of skeletal muscle tissue development GO:0048643 1 0.501
protein deacylation GO:0035601 39 0.499
response to organonitrogen compound GO:0010243 156 0.498
Human
regulation of transmembrane transporter activity GO:0022898 74 0.492
response to hormone GO:0009725 175 0.488
Human Rat
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.483
positive regulation of cell proliferation GO:0008284 301 0.475
neuron projection development GO:0031175 106 0.475
generation of precursor metabolites and energy GO:0006091 68 0.470
Mouse
platelet formation GO:0030220 4 0.470
regulation of cardiac muscle tissue growth GO:0055021 4 0.468
neurogenesis GO:0022008 169 0.468
Worm
histone modification GO:0016570 251 0.466
regulation of blood circulation GO:1903522 59 0.456
Mouse
positive regulation of cell development GO:0010720 92 0.453
syncytium formation by plasma membrane fusion GO:0000768 2 0.449
regulation of ion transmembrane transport GO:0034765 132 0.445
photoreceptor cell differentiation GO:0046530 2 0.444
cell fate commitment GO:0045165 27 0.443
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.440
positive regulation of cardiac muscle tissue development GO:0055025 6 0.432
protein deacetylation GO:0006476 38 0.426
cellular ketone metabolic process GO:0042180 80 0.423
regionalization GO:0003002 29 0.422
segmentation GO:0035282 4 0.420
single organism membrane organization GO:0044802 268 0.419
cardiac muscle cell development GO:0055013 5 0.418
muscle structure development GO:0061061 98 0.418
cardiac muscle cell differentiation GO:0055007 15 0.417
regulation of cardiac muscle tissue development GO:0055024 13 0.416
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.414
positive regulation of cardiac muscle cell proliferation GO:0060045 2 0.408
muscle cell development GO:0055001 29 0.393
Mouse
muscle fiber development GO:0048747 16 0.385
Mouse
cognition GO:0050890 43 0.381
Fly
single organism cellular localization GO:1902580 332 0.377
ras protein signal transduction GO:0007265 73 0.369
replacement ossification GO:0036075 1 0.366
regulation of ion transport GO:0043269 189 0.365
regulation of neuron projection development GO:0010975 57 0.362
positive regulation of nervous system development GO:0051962 54 0.361
transmembrane transport GO:0055085 399 0.359
epithelium development GO:0060429 227 0.354
positive regulation of programmed cell death GO:0043068 249 0.352
Rat
small gtpase mediated signal transduction GO:0007264 78 0.352
negative regulation of cell death GO:0060548 345 0.344
digestive tract development GO:0048565 75 0.342
generation of neurons GO:0048699 152 0.341
Worm
cell projection organization GO:0030030 252 0.333
Rat
negative regulation of apoptotic process GO:0043066 316 0.333
heart field specification GO:0003128 2 0.331
urogenital system development GO:0001655 65 0.325
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.323
multicellular organismal response to stress GO:0033555 1 0.322
renal tubule development GO:0061326 19 0.322
response to transforming growth factor beta GO:0071559 94 0.320
multicellular organismal signaling GO:0035637 34 0.316
positive regulation of organ growth GO:0046622 2 0.314
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.313
regulation of dephosphorylation GO:0035303 96 0.313
regulation of cell cycle GO:0051726 393 0.303
regulation of system process GO:0044057 101 0.302
Mouse
regulation of cell projection organization GO:0031344 107 0.299
Rat
bone mineralization GO:0030282 34 0.298
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.298
regulation of muscle tissue development GO:1901861 26 0.297
Mouse
cellular response to organonitrogen compound GO:0071417 124 0.294
Human
connective tissue development GO:0061448 39 0.291
cell morphogenesis GO:0000902 296 0.290
Zebrafish
anatomical structure formation involved in morphogenesis GO:0048646 284 0.289
Human
renal tubule morphogenesis GO:0061333 14 0.288
dna templated transcription elongation GO:0006354 25 0.286
neurological system process GO:0050877 163 0.284
Fly
organ morphogenesis GO:0009887 147 0.284
Zebrafish
fear response GO:0042596 0 0.277
system process GO:0003008 349 0.274
Mouse Fly
cellular macromolecular complex assembly GO:0034622 324 0.267
regulation of dna templated transcription elongation GO:0032784 23 0.266
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.263
negative regulation of protein modification process GO:0031400 200 0.263
histone deacetylation GO:0016575 32 0.261
protein modification by small protein conjugation GO:0032446 342 0.257
response to metal ion GO:0010038 84 0.256
cell proliferation in bone marrow GO:0071838 1 0.254
response to other organism GO:0051707 261 0.253
regulation of anatomical structure morphogenesis GO:0022603 286 0.251
Human Zebrafish
regulation of cellular component biogenesis GO:0044087 281 0.251
Rat
regulation of cellular ketone metabolic process GO:0010565 50 0.251
skeletal muscle tissue development GO:0007519 24 0.246
Mouse
ubiquitin dependent protein catabolic process GO:0006511 206 0.245
nucleoside triphosphate metabolic process GO:0009141 422 0.243
circulatory system development GO:0072359 262 0.239
Human
embryonic viscerocranium morphogenesis GO:0048703 1 0.238
negative regulation of peptidyl serine dephosphorylation GO:1902309 1 0.236
response to nitrogen compound GO:1901698 184 0.235
Human
biomineral tissue development GO:0031214 39 0.233
negative regulation of ossification GO:0030279 21 0.230
Human Mouse
striated muscle cell development GO:0055002 27 0.224
Mouse
negative regulation of integrin activation GO:0033624 2 0.222
single organism carbohydrate metabolic process GO:0044723 193 0.220
Mouse
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 17 0.216
cell division GO:0051301 168 0.214
response to external biotic stimulus GO:0043207 261 0.213
embryonic organ morphogenesis GO:0048562 24 0.212
Zebrafish
rhythmic process GO:0048511 31 0.211
regulation of tor signaling GO:0032006 30 0.211
specification of organ identity GO:0010092 3 0.208
gtp metabolic process GO:0046039 239 0.207
negative regulation of epithelial cell proliferation GO:0050680 48 0.206
somatic stem cell maintenance GO:0035019 4 0.205
determination of adult lifespan GO:0008340 2 0.205
embryonic morphogenesis GO:0048598 85 0.200
Zebrafish
epithelium migration GO:0090132 119 0.200
Human
multicellular organismal aging GO:0010259 3 0.197
myoblast fusion GO:0007520 1 0.196
neuron apoptotic process GO:0051402 39 0.192
Rat
cytoplasmic transport GO:0016482 379 0.191
cellular response to toxic substance GO:0097237 4 0.191
muscle tissue development GO:0060537 62 0.191
Mouse
purine containing compound catabolic process GO:0072523 411 0.188
protein targeting to nucleus GO:0044744 104 0.188
intracellular receptor signaling pathway GO:0030522 104 0.187
response to inorganic substance GO:0010035 127 0.185
negative regulation of protein metabolic process GO:0051248 391 0.185
axon cargo transport GO:0008088 2 0.185
positive regulation of osteoblast differentiation GO:0045669 23 0.182
response to extracellular stimulus GO:0009991 85 0.182
cell fate specification GO:0001708 8 0.182
macromolecule deacylation GO:0098732 41 0.181
regulation of alkaline phosphatase activity GO:0010692 2 0.180
female gamete generation GO:0007292 2 0.180
positive regulation of cell death GO:0010942 263 0.179
Rat
synaptic transmission GO:0007268 61 0.178
positive regulation of heart growth GO:0060421 2 0.177
chordate embryonic development GO:0043009 34 0.177
Zebrafish
cellular response to dna damage stimulus GO:0006974 379 0.176
tube development GO:0035295 125 0.175
ribonucleoside triphosphate catabolic process GO:0009203 391 0.174
purine nucleoside triphosphate catabolic process GO:0009146 392 0.173
endochondral bone morphogenesis GO:0060350 3 0.172
endochondral ossification GO:0001958 1 0.171
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.169
positive regulation of apoptotic process GO:0043065 246 0.168
Rat
regulation of protein localization GO:0032880 296 0.167
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.167
post embryonic development GO:0009791 2 0.167
Worm
cardiac myofibril assembly GO:0055003 3 0.166
regulation of epithelial cell proliferation GO:0050678 113 0.165
glucocorticoid metabolic process GO:0008211 10 0.165
regulation of neural precursor cell proliferation GO:2000177 4 0.164
microtubule cytoskeleton organization GO:0000226 176 0.164
leukocyte differentiation GO:0002521 98 0.163
embryonic heart tube morphogenesis GO:0003143 8 0.163
cell type specific apoptotic process GO:0097285 125 0.163
Rat
cellular response to molecule of bacterial origin GO:0071219 62 0.161
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.160
response to growth factor GO:0070848 205 0.156
actin cytoskeleton organization GO:0030036 207 0.153
cellular component assembly involved in morphogenesis GO:0010927 73 0.151
negative regulation of protein dephosphorylation GO:0035308 3 0.150
intracellular bile acid receptor signaling pathway GO:0038185 1 0.150
regulation of sarcomere organization GO:0060297 3 0.150
blood vessel development GO:0001568 172 0.149
Human
embryo development GO:0009790 123 0.149
Zebrafish
negative regulation of programmed cell death GO:0043069 321 0.147
inflammatory cell apoptotic process GO:0006925 3 0.147
regulation of growth GO:0040008 165 0.146
single organism nuclear import GO:1902593 104 0.145
skeletal myofibril assembly GO:0014866 3 0.145
regulation of nucleoside metabolic process GO:0009118 209 0.144
positive regulation of muscle tissue development GO:1901863 7 0.144
cardiac ventricle development GO:0003231 23 0.142
positive regulation of cardiac muscle tissue growth GO:0055023 2 0.141
apoptotic mitochondrial changes GO:0008637 57 0.141
glutamate receptor signaling pathway GO:0007215 23 0.141
actomyosin structure organization GO:0031032 59 0.140
regulation of cell activation GO:0050865 125 0.139
regulation of ras protein signal transduction GO:0046578 155 0.139
cardiocyte differentiation GO:0035051 23 0.139
lipid metabolic process GO:0006629 381 0.139
response to biotic stimulus GO:0009607 276 0.138
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.137
cellular response to nitrogen compound GO:1901699 144 0.137
Human
positive regulation of striated muscle tissue development GO:0045844 7 0.136
internal protein amino acid acetylation GO:0006475 101 0.135
ossification GO:0001503 121 0.135
Human Mouse
blood vessel endothelial cell migration GO:0043534 42 0.135
Human
nucleotide catabolic process GO:0009166 408 0.134
regulation of cell motility GO:2000145 299 0.134
Human Rat
anterior posterior axis specification embryo GO:0008595 2 0.131
blood vessel morphogenesis GO:0048514 162 0.131
Human
striated muscle tissue development GO:0014706 59 0.131
Mouse
negative regulation of epithelial cell migration GO:0010633 38 0.128
Human
mitotic cell cycle phase transition GO:0044772 162 0.126
response to oxygen containing compound GO:1901700 369 0.125
Human
muscle adaptation GO:0043500 12 0.124
positive regulation of neuron differentiation GO:0045666 40 0.124
behavioral fear response GO:0001662 0 0.124
endomembrane system organization GO:0010256 196 0.123
regulation of proteolysis GO:0030162 293 0.119
internal peptidyl lysine acetylation GO:0018393 97 0.119
regulation of transporter activity GO:0032409 82 0.118
regulation of wnt signaling pathway GO:0030111 123 0.117
striated muscle cell differentiation GO:0051146 43 0.116
cellular carbohydrate metabolic process GO:0044262 84 0.114
Mouse
cardiac cell development GO:0055006 5 0.114
cellular protein catabolic process GO:0044257 261 0.114
skeletal muscle organ development GO:0060538 26 0.112
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.110
cellular response to oxygen containing compound GO:1901701 276 0.110
Human
response to organic cyclic compound GO:0014070 204 0.109
regulation of cytoskeleton organization GO:0051493 177 0.109
response to radiation GO:0009314 151 0.109
oocyte development GO:0048599 1 0.109
pattern specification process GO:0007389 43 0.108
membrane organization GO:0061024 292 0.108
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 1 0.107
protein processing GO:0016485 226 0.107
positive regulation of defense response GO:0031349 87 0.106
positive regulation of lymphocyte activation GO:0051251 73 0.106
wnt signaling pathway GO:0016055 156 0.105
cell differentiation involved in kidney development GO:0061005 9 0.104
dephosphorylation GO:0016311 209 0.103
organelle localization GO:0051640 84 0.103
response to osmotic stress GO:0006970 17 0.103
nuclear migration GO:0007097 1 0.102
gtp catabolic process GO:0006184 237 0.101
cellular response to organic cyclic compound GO:0071407 127 0.100
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter GO:0072367 4 0.100
visual learning GO:0008542 1 0.100
positive regulation of hydrolase activity GO:0051345 331 0.100
lipid storage GO:0019915 28 0.098
inorganic cation transmembrane transport GO:0098662 194 0.098
muscle organ development GO:0007517 56 0.098
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.098
regulation of organelle assembly GO:1902115 40 0.097
cellular protein complex assembly GO:0043623 188 0.097
positive regulation of cell proliferation in bone marrow GO:0071864 1 0.096
negative regulation of neuron apoptotic process GO:0043524 23 0.096
limbic system development GO:0021761 3 0.096
male meiosis GO:0007140 1 0.096
monocarboxylic acid metabolic process GO:0032787 185 0.095
Mouse
muscle cell differentiation GO:0042692 63 0.095
positive regulation of synaptic transmission GO:0050806 4 0.095
hindbrain development GO:0030902 3 0.095
glycerolipid metabolic process GO:0046486 107 0.095
cardiac muscle hypertrophy GO:0003300 14 0.094
protein sumoylation GO:0016925 25 0.094
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.094
protein oligomerization GO:0051259 173 0.094
regulation of leukocyte activation GO:0002694 115 0.094
heart morphogenesis GO:0003007 48 0.094
cartilage morphogenesis GO:0060536 1 0.094
cellular response to biotic stimulus GO:0071216 71 0.093
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.093
regulation of peptidyl serine dephosphorylation GO:1902308 2 0.093
blastoderm segmentation GO:0007350 2 0.092
positive regulation of behavior GO:0048520 60 0.092
thalamus development GO:0021794 2 0.092
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.091
single organism behavior GO:0044708 28 0.091
Fly
release of cytochrome c from mitochondria GO:0001836 35 0.091
striated muscle myosin thick filament assembly GO:0071688 2 0.091
lipid catabolic process GO:0016042 84 0.091
positive regulation of phosphorylation GO:0042327 394 0.090
cell growth GO:0016049 160 0.089
oogenesis GO:0048477 2 0.089
negative regulation of cellular component organization GO:0051129 235 0.088
intracellular protein transport GO:0006886 270 0.088
cardiac conduction GO:0061337 23 0.088
regulation of cell growth GO:0001558 135 0.087
positive regulation of angiogenesis GO:0045766 51 0.087
Human
dendritic spine development GO:0060996 6 0.087
negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 6 0.086
Human
negative regulation of cell cycle process GO:0010948 121 0.086
regulation of purine nucleotide metabolic process GO:1900542 264 0.086
response to lipid GO:0033993 206 0.085
apoptotic signaling pathway GO:0097190 268 0.085
positive regulation of neurogenesis GO:0050769 49 0.085
negative regulation of cellular component movement GO:0051271 106 0.084
Human
regulation of mononuclear cell proliferation GO:0032944 65 0.084
ribonucleoside triphosphate metabolic process GO:0009199 412 0.084
nephron tubule development GO:0072080 17 0.084
protein targeting GO:0006605 187 0.084
digestive system development GO:0055123 75 0.083
oocyte differentiation GO:0009994 2 0.082
enzyme linked receptor protein signaling pathway GO:0007167 303 0.082
mitochondrion localization GO:0051646 10 0.081
tissue morphogenesis GO:0048729 96 0.081
guanosine containing compound metabolic process GO:1901068 244 0.081
brain development GO:0007420 97 0.081
positive regulation of protein binding GO:0032092 24 0.080
negative regulation of phosphate metabolic process GO:0045936 267 0.080
organophosphate catabolic process GO:0046434 430 0.080
tor signaling GO:0031929 39 0.079
negative regulation of cellular protein metabolic process GO:0032269 353 0.079
negative regulation of growth GO:0045926 97 0.079
monovalent inorganic cation transport GO:0015672 128 0.079
regulation of protein transport GO:0051223 213 0.079
oxidation reduction process GO:0055114 396 0.079
purine nucleoside monophosphate metabolic process GO:0009126 186 0.078
muscle hypertrophy GO:0014896 14 0.077
epithelial cell differentiation involved in kidney development GO:0035850 9 0.077
regulation of mitotic cell cycle phase transition GO:1901990 118 0.077
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.077
Human
ribonucleotide catabolic process GO:0009261 405 0.077
protein acylation GO:0043543 138 0.076
negative regulation of muscle cell differentiation GO:0051148 17 0.076
regulation of postsynaptic membrane potential GO:0060078 1 0.075
regulation of behavior GO:0050795 82 0.075
positive regulation of bone mineralization GO:0030501 19 0.074
inorganic ion transmembrane transport GO:0098660 231 0.074
morphogenesis of an epithelium GO:0002009 60 0.073
cellular response to insulin stimulus GO:0032869 41 0.073
Human
cardiac muscle tissue growth GO:0055017 6 0.073
neuron development GO:0048666 113 0.072
protein maturation GO:0051604 233 0.072
leukocyte activation GO:0045321 164 0.072
striated muscle adaptation GO:0014888 4 0.072
regulation of gtpase activity GO:0043087 180 0.072
regulation of cell cycle process GO:0010564 266 0.072
defense response GO:0006952 315 0.071
cell migration involved in sprouting angiogenesis GO:0002042 19 0.071
Human
anterior posterior axis specification GO:0009948 2 0.071
kidney development GO:0001822 53 0.071
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 5 0.071
establishment of protein localization to organelle GO:0072594 172 0.070
protein localization to nucleus GO:0034504 136 0.069
muscle system process GO:0003012 81 0.069
Mouse
cellular response to lipopolysaccharide GO:0071222 57 0.069
smooth muscle cell differentiation GO:0051145 8 0.069
immune response GO:0006955 307 0.068
heart valve development GO:0003170 8 0.068
regulation of actin filament based process GO:0032970 141 0.068
response to toxic substance GO:0009636 37 0.068
glucocorticoid catabolic process GO:0006713 1 0.067
steroid metabolic process GO:0008202 94 0.067
response to decreased oxygen levels GO:0036293 96 0.067
regulation of lymphocyte proliferation GO:0050670 64 0.067
skeletal muscle cell differentiation GO:0035914 6 0.067
positive regulation of ras gtpase activity GO:0032320 117 0.066
cellular response to growth factor stimulus GO:0071363 197 0.066
regulation of dendrite development GO:0050773 18 0.066
regulation of protein ubiquitination GO:0031396 95 0.066
myeloid cell differentiation GO:0030099 117 0.065
regulation of organ growth GO:0046620 7 0.065
atp catabolic process GO:0006200 157 0.064
regulation of megakaryocyte differentiation GO:0045652 22 0.064
negative regulation of phosphorylation GO:0042326 174 0.064
striated muscle hypertrophy GO:0014897 14 0.064
regulation of glycolytic process by regulation of transcription from rna polymerase ii promoter GO:0072361 2 0.063
nucleoside phosphate catabolic process GO:1901292 412 0.063
nephron epithelium development GO:0072009 23 0.063
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 3 0.063
protein ubiquitination GO:0016567 314 0.062
cellular response to osmotic stress GO:0071470 8 0.062
positive regulation of cellular catabolic process GO:0031331 284 0.062
regulation of immune response GO:0050776 201 0.062
ribonucleoside catabolic process GO:0042454 406 0.062
sodium ion transmembrane transport GO:0035725 59 0.062
myosin filament assembly GO:0031034 2 0.061
pyruvate metabolic process GO:0006090 26 0.060
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.060
regulation of establishment of protein localization GO:0070201 242 0.060
regulation of adaptive immune response GO:0002819 33 0.060
regulation of mapk cascade GO:0043408 262 0.060
positive regulation of nucleotide metabolic process GO:0045981 230 0.060
cardiac muscle cell proliferation GO:0060038 6 0.060
cellular response to peptide GO:1901653 59 0.060
Human
glomerulus development GO:0032835 15 0.060
microtubule based process GO:0007017 210 0.060
regulation of endopeptidase activity GO:0052548 170 0.059
negative regulation of chromatin silencing GO:0031936 4 0.059
embryonic skeletal system development GO:0048706 13 0.059
Zebrafish
somatic muscle development GO:0007525 1 0.058
cardiac chamber morphogenesis GO:0003206 26 0.058
nucleoside catabolic process GO:0009164 408 0.058
negative regulation of cell growth GO:0030308 83 0.058
cardiovascular system development GO:0072358 262 0.058
Human
cation transport GO:0006812 331 0.058
regulation of cell cycle phase transition GO:1901987 126 0.058
protein localization to plasma membrane GO:0072659 93 0.057
negative regulation of cell size GO:0045792 3 0.057
activation of immune response GO:0002253 114 0.057
response to oxygen levels GO:0070482 100 0.057
central nervous system development GO:0007417 123 0.056
positive regulation of lymphocyte proliferation GO:0050671 46 0.056
glycosyl compound catabolic process GO:1901658 413 0.056
regulation of secretion by cell GO:1903530 177 0.056
antimicrobial humoral response GO:0019730 26 0.055
activation of mapkk activity GO:0000186 18 0.055
positive regulation of organelle organization GO:0010638 195 0.055
cellular response to mechanical stimulus GO:0071260 39 0.055
Rat
response to molecule of bacterial origin GO:0002237 82 0.055
regulation of cellular amine metabolic process GO:0033238 11 0.055
regulation of cell morphogenesis GO:0022604 153 0.054
Zebrafish
circulatory system process GO:0003013 113 0.054
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 2 0.054

HDAC4 disease predictions

Disease DO term ID Size Probability Func Analog Org