Homo sapiens

16 known processes

ATG3

ATG3 autophagy related 3 homolog (S. cerevisiae)

(Aliases: FLJ22125,MGC15201,APG3-LIKE,APG3,DKFZp564M1178,PC3-96,APG3L)

ATG3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macroautophagy GO:0016236 39 1.000
Yeast
autophagic vacuole assembly GO:0000045 19 0.999
Yeast
c terminal protein amino acid modification GO:0018410 1 0.995
Yeast
cellular response to starvation GO:0009267 58 0.994
Yeast
autophagy GO:0006914 88 0.994
Yeast
regulation of autophagy GO:0010506 52 0.987
positive regulation of autophagy GO:0010508 24 0.985
cellular response to nutrient levels GO:0031669 69 0.983
Yeast
determination of adult lifespan GO:0008340 2 0.979
Worm
multicellular organismal aging GO:0010259 3 0.955
Worm
lipoprotein biosynthetic process GO:0042158 33 0.950
Yeast
autophagic cell death GO:0048102 3 0.945
cellular response to external stimulus GO:0071496 111 0.928
Yeast
response to extracellular stimulus GO:0009991 85 0.920
Yeast
vacuole organization GO:0007033 44 0.920
Yeast
response to hyperoxia GO:0055093 4 0.916
lipoprotein metabolic process GO:0042157 42 0.899
Yeast
protein lipidation GO:0006497 33 0.898
Yeast
cytoplasmic transport GO:0016482 379 0.878
Yeast
vasodilation GO:0042311 4 0.874
response to starvation GO:0042594 59 0.865
Yeast
single organism membrane organization GO:0044802 268 0.850
Yeast
vacuolar transport GO:0007034 34 0.834
Yeast
intracellular protein transport GO:0006886 270 0.825
Yeast
protein targeting to vacuole GO:0006623 8 0.824
Yeast
necrotic cell death GO:0070265 21 0.797
membrane organization GO:0061024 292 0.780
Yeast
regulation of cilium assembly GO:1902017 6 0.755
protein targeting GO:0006605 187 0.754
Yeast
protein modification by small protein conjugation GO:0032446 342 0.730
single organism cellular localization GO:1902580 332 0.727
Yeast
response to nutrient levels GO:0031667 81 0.698
Yeast
positive regulation of catabolic process GO:0009896 310 0.647
regulation of macroautophagy GO:0016241 19 0.639
protein localization to organelle GO:0033365 280 0.616
Yeast
positive regulation of cellular catabolic process GO:0031331 284 0.565
establishment of protein localization to organelle GO:0072594 172 0.557
Yeast
post translational protein modification GO:0043687 7 0.557
Yeast
cellular amino acid metabolic process GO:0006520 116 0.535
aging GO:0007568 66 0.511
Worm
organelle assembly GO:0070925 176 0.498
Yeast
anatomical structure formation involved in morphogenesis GO:0048646 284 0.492
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.451
negative regulation of cell death GO:0060548 345 0.449
positive regulation of apoptotic process GO:0043065 246 0.434
cilium assembly GO:0042384 63 0.433
response to other organism GO:0051707 261 0.426
histone acetylation GO:0016573 93 0.412
cellular component assembly involved in morphogenesis GO:0010927 73 0.398
cell development GO:0048468 328 0.398
interspecies interaction between organisms GO:0044419 156 0.385
multi organism cellular process GO:0044764 156 0.378
viral process GO:0016032 146 0.368
viral life cycle GO:0019058 132 0.365
defense response to other organism GO:0098542 129 0.361
protein localization to vacuole GO:0072665 11 0.360
Yeast
cellular amine metabolic process GO:0044106 41 0.350
peptidyl lysine acetylation GO:0018394 101 0.348
divalent metal ion transport GO:0070838 152 0.345
myosin filament assembly GO:0031034 2 0.321
cardiac muscle tissue development GO:0048738 39 0.314
negative regulation of cellular amine metabolic process GO:0033239 3 0.308
protein acylation GO:0043543 138 0.298
regulation of calcium ion transport GO:0051924 79 0.295
internal peptidyl lysine acetylation GO:0018393 97 0.293
striated muscle cell differentiation GO:0051146 43 0.285
cellular response to extracellular stimulus GO:0031668 72 0.278
Yeast
blood circulation GO:0008015 113 0.254
negative regulation of histone acetylation GO:0035067 6 0.251
amine metabolic process GO:0009308 44 0.246
female gamete generation GO:0007292 2 0.228
defense response to bacterium GO:0042742 63 0.217
growth GO:0040007 202 0.216
Worm
actin filament based process GO:0030029 224 0.215
negative regulation of protein metabolic process GO:0051248 391 0.196
histone h4 acetylation GO:0043967 47 0.184
post embryonic development GO:0009791 2 0.182
myosin filament organization GO:0031033 2 0.181
regulation of cellular amino acid metabolic process GO:0006521 6 0.180
defense response GO:0006952 315 0.179
calcium ion homeostasis GO:0055074 122 0.178
regulation of defense response GO:0031347 154 0.174
regulation of cellular response to stress GO:0080135 244 0.173
cellular component morphogenesis GO:0032989 314 0.173
response to biotic stimulus GO:0009607 276 0.171
regulation of cytoplasmic transport GO:1903649 149 0.168
immune effector process GO:0002252 159 0.165
blood vessel remodeling GO:0001974 2 0.161
cellular response to hyperoxia GO:0071455 4 0.160
regulation of body fluid levels GO:0050878 99 0.160
regulation of multi organism process GO:0043900 157 0.158
purine ribonucleoside metabolic process GO:0046128 437 0.158
response to external biotic stimulus GO:0043207 261 0.157
protein acetylation GO:0006473 116 0.156
oogenesis GO:0048477 2 0.154
regulation of cellular amine metabolic process GO:0033238 11 0.153
internal protein amino acid acetylation GO:0006475 101 0.151
negative regulation of chromatin modification GO:1903309 21 0.150
regulation of defense response to virus GO:0050688 33 0.146
response to fungus GO:0009620 4 0.145
cellular response to oxygen levels GO:0071453 55 0.140
cytokine secretion involved in immune response GO:0002374 7 0.139
cellular ion homeostasis GO:0006873 168 0.134
metal ion transport GO:0030001 272 0.133
regulation of calcium ion transport into cytosol GO:0010522 33 0.131
secretion by tissue GO:0032941 9 0.130
establishment of protein localization to vacuole GO:0072666 8 0.128
Yeast
positive regulation of response to extracellular stimulus GO:0032106 14 0.128
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.127
cardiovascular system development GO:0072358 262 0.126
organophosphate biosynthetic process GO:0090407 163 0.124
covalent chromatin modification GO:0016569 254 0.123
ribonucleoside triphosphate metabolic process GO:0009199 412 0.121
cytosolic calcium ion transport GO:0060401 48 0.120
protein catabolic process GO:0030163 325 0.118
positive regulation of programmed cell death GO:0043068 249 0.114
regulation of anatomical structure morphogenesis GO:0022603 286 0.108
cellular divalent inorganic cation homeostasis GO:0072503 128 0.107
negative regulation of organelle organization GO:0010639 126 0.106
regulation of blood vessel size GO:0050880 18 0.105
regulation of cellular ketone metabolic process GO:0010565 50 0.105
mitochondrion degradation GO:0000422 8 0.105
Yeast
cellular ketone metabolic process GO:0042180 80 0.104
muscle cell development GO:0055001 29 0.101
positive regulation of mucus secretion GO:0070257 1 0.099
regulation of response to external stimulus GO:0032101 222 0.098
regulation of response to biotic stimulus GO:0002831 55 0.093
heart contraction GO:0060047 62 0.092
vascular process in circulatory system GO:0003018 29 0.090
mucus secretion GO:0070254 1 0.089
histone h4 k16 acetylation GO:0043984 14 0.086
nucleoside phosphate catabolic process GO:1901292 412 0.085
cilium morphogenesis GO:0060271 75 0.082
peptidyl lysine modification GO:0018205 144 0.081
striated muscle cell development GO:0055002 27 0.079
reactive oxygen species metabolic process GO:0072593 75 0.078
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.074
regulation of anatomical structure size GO:0090066 101 0.074
regulation of protein catabolic process GO:0042176 155 0.073
regulation of protein localization GO:0032880 296 0.073
muscle cell differentiation GO:0042692 63 0.072
cell projection assembly GO:0030031 126 0.072
viral rna genome replication GO:0039694 9 0.072
negative regulation of cellular protein metabolic process GO:0032269 353 0.072
tissue remodeling GO:0048771 16 0.071
circulatory system process GO:0003013 113 0.071
cell part morphogenesis GO:0032990 137 0.071
chromatin organization GO:0006325 351 0.071
regulation of chromosome organization GO:0033044 103 0.071
nervous system development GO:0007399 293 0.070
embryo development GO:0009790 123 0.070
negative regulation of cellular component organization GO:0051129 235 0.069
histone modification GO:0016570 251 0.069
actin cytoskeleton organization GO:0030036 207 0.067
regulation of tube size GO:0035150 18 0.067
positive regulation of response to external stimulus GO:0032103 88 0.066
regulation of chromatin modification GO:1903308 51 0.066
regulation of metal ion transport GO:0010959 120 0.066
organophosphate catabolic process GO:0046434 430 0.066
chromatin modification GO:0016568 298 0.065
cell morphogenesis GO:0000902 296 0.065
muscle structure development GO:0061061 98 0.065
ventricular cardiac muscle cell differentiation GO:0055012 1 0.064
negative regulation of chromosome organization GO:2001251 48 0.063
secretion GO:0046903 254 0.059
gtp metabolic process GO:0046039 239 0.058
negative regulation of programmed cell death GO:0043069 321 0.058
cellular macromolecular complex assembly GO:0034622 324 0.057
regulation of protein acetylation GO:1901983 25 0.055
system process GO:0003008 349 0.054
regulation of homeostatic process GO:0032844 121 0.053
actomyosin structure organization GO:0031032 59 0.052
cytokine secretion GO:0050663 64 0.051
nucleotide catabolic process GO:0009166 408 0.051
cellular protein complex assembly GO:0043623 188 0.051
regulation of protein ubiquitination GO:0031396 95 0.051
cellular calcium ion homeostasis GO:0006874 117 0.051
regulation of reactive oxygen species metabolic process GO:2000377 41 0.051
response to abiotic stimulus GO:0009628 336 0.050
regulation of protein secretion GO:0050708 86 0.050
cell projection morphogenesis GO:0048858 129 0.050
regulation of response to nutrient levels GO:0032107 22 0.050
negative regulation of protein ubiquitination GO:0031397 35 0.049
sequestering of calcium ion GO:0051208 17 0.048
response to drug GO:0042493 81 0.047
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.046
defense response to virus GO:0051607 71 0.046
cytosolic calcium ion homeostasis GO:0051480 89 0.046
immune response GO:0006955 307 0.046
regulation of secretion by cell GO:1903530 177 0.045
purine ribonucleoside catabolic process GO:0046130 398 0.043
maintenance of location GO:0051235 112 0.043
response to virus GO:0009615 126 0.043
nucleoside catabolic process GO:0009164 408 0.043
positive regulation of protein catabolic process GO:0045732 75 0.042
regulation of ion homeostasis GO:2000021 73 0.042
response to oxygen levels GO:0070482 100 0.040
regulation of sequestering of calcium ion GO:0051282 41 0.040
positive regulation of transport GO:0051050 336 0.038
regulation of response to extracellular stimulus GO:0032104 22 0.038
aggrephagy GO:0035973 1 0.038
cellular cation homeostasis GO:0030003 163 0.038
cellular homeostasis GO:0019725 196 0.038
organonitrogen compound biosynthetic process GO:1901566 200 0.037
negative regulation of homeostatic process GO:0032845 59 0.037
regulation of production of molecular mediator of immune response GO:0002700 25 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.037
negative regulation of sequestering of calcium ion GO:0051283 41 0.036
regulation of protein transport GO:0051223 213 0.035
cell projection organization GO:0030030 252 0.035
calcium ion transport into cytosol GO:0060402 48 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
ribonucleotide catabolic process GO:0009261 405 0.033
purine nucleoside catabolic process GO:0006152 398 0.033
regulation of cytokine secretion GO:0050707 57 0.033
negative regulation of protein modification process GO:0031400 200 0.033
positive regulation of secretion GO:0051047 116 0.033
regulation of peptidyl lysine acetylation GO:2000756 22 0.032
cilium organization GO:0044782 68 0.032
regulation of secretion GO:0051046 194 0.032
striated muscle myosin thick filament assembly GO:0071688 2 0.032
glycosyl compound catabolic process GO:1901658 413 0.032
defense response to gram positive bacterium GO:0050830 29 0.031
endosomal transport GO:0016197 129 0.031
protein maturation GO:0051604 233 0.031
positive regulation of cell death GO:0010942 263 0.030
regulation of cell projection organization GO:0031344 107 0.030
reproductive process GO:0022414 106 0.029
regulation of immune effector process GO:0002697 91 0.029
purine containing compound catabolic process GO:0072523 411 0.029
microtubule cytoskeleton organization GO:0000226 176 0.029
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.028
metal ion homeostasis GO:0055065 169 0.028
purine nucleoside triphosphate metabolic process GO:0009144 412 0.028
cation transport GO:0006812 331 0.027
organelle fission GO:0048285 149 0.027
regulation of ion transport GO:0043269 189 0.027
negative regulation of histone modification GO:0031057 19 0.026
embryo development ending in birth or egg hatching GO:0009792 34 0.026
calcium ion transport GO:0006816 147 0.026
regulation of intracellular transport GO:0032386 195 0.026
nucleoside phosphate biosynthetic process GO:1901293 109 0.025
cytokine production GO:0001816 247 0.025
multi organism reproductive process GO:0044703 54 0.025
negative regulation of cellular catabolic process GO:0031330 83 0.025
protein processing GO:0016485 226 0.025
divalent inorganic cation homeostasis GO:0072507 136 0.025
heart development GO:0007507 95 0.024
positive regulation of phosphorylation GO:0042327 394 0.024
sexual reproduction GO:0019953 37 0.023
heart process GO:0003015 62 0.023
regulation of establishment of protein localization GO:0070201 242 0.023
production of molecular mediator of immune response GO:0002440 37 0.023
ribonucleotide biosynthetic process GO:0009260 81 0.023
ion homeostasis GO:0050801 230 0.023
regulation of cell morphogenesis GO:0022604 153 0.023
striated muscle tissue development GO:0014706 59 0.023
regulation of histone modification GO:0031056 47 0.023
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
brain development GO:0007420 97 0.022
cellular metal ion homeostasis GO:0006875 146 0.022
regulation of cellular component biogenesis GO:0044087 281 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
mapk cascade GO:0000165 288 0.021
viral genome replication GO:0019079 50 0.021
circulatory system development GO:0072359 262 0.021
regulation of purine nucleotide catabolic process GO:0033121 205 0.021
body fluid secretion GO:0007589 9 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
positive regulation of macroautophagy GO:0016239 12 0.020
central nervous system development GO:0007417 123 0.020
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
multicellular organismal reproductive process GO:0048609 40 0.020
regulation of mucus secretion GO:0070255 1 0.020
regulation of cytokine production involved in immune response GO:0002718 22 0.020
negative regulation of axonogenesis GO:0050771 4 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
cardiocyte differentiation GO:0035051 23 0.020
reproduction GO:0000003 63 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
secretion by cell GO:0032940 226 0.019
nucleoside monophosphate metabolic process GO:0009123 191 0.019
regulation of nucleoside metabolic process GO:0009118 209 0.019
nitrogen compound transport GO:0071705 191 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
regulation of cytokine production GO:0001817 232 0.018
protein secretion GO:0009306 98 0.018
muscle tissue development GO:0060537 62 0.018
regulation of cellular protein catabolic process GO:1903362 96 0.018
rna interference GO:0016246 4 0.018
regulation of histone acetylation GO:0035065 19 0.018
regulation of proteolysis GO:0030162 293 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.018
cellular chemical homeostasis GO:0055082 180 0.018
vesicle mediated transport GO:0016192 371 0.018
response to endoplasmic reticulum stress GO:0034976 49 0.017
positive regulation of cell proliferation GO:0008284 301 0.017
single organism reproductive process GO:0044702 98 0.017
dephosphorylation GO:0016311 209 0.017
glycerolipid metabolic process GO:0046486 107 0.017
regulation of binding GO:0051098 111 0.017
chemical homeostasis GO:0048878 306 0.016
cell division GO:0051301 168 0.016
purine containing compound biosynthetic process GO:0072522 88 0.016
multicellular organism reproduction GO:0032504 42 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.016
purine nucleotide catabolic process GO:0006195 405 0.015
mitotic nuclear division GO:0007067 119 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
developmental process involved in reproduction GO:0003006 66 0.015
innate immune response GO:0045087 178 0.015
ribose phosphate biosynthetic process GO:0046390 82 0.015
positive regulation of gtpase activity GO:0043547 166 0.014
negative regulation of protein catabolic process GO:0042177 59 0.014
nuclear transport GO:0051169 179 0.014
regulation of cell projection assembly GO:0060491 47 0.014
regulation of chromatin organization GO:1902275 56 0.014
receptor mediated endocytosis GO:0006898 84 0.014
cell morphogenesis involved in differentiation GO:0000904 144 0.013
cation homeostasis GO:0055080 189 0.013
multicellular organismal response to stress GO:0033555 1 0.013
apoptotic signaling pathway GO:0097190 268 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
negative regulation of peptidyl lysine acetylation GO:2000757 8 0.013
gtp catabolic process GO:0006184 237 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
glycerophospholipid biosynthetic process GO:0046474 40 0.012
meiosis i GO:0007127 4 0.012
sister chromatid segregation GO:0000819 54 0.012
establishment of organelle localization GO:0051656 59 0.012
negative regulation of protein acetylation GO:1901984 11 0.012
cell growth GO:0016049 160 0.012
segmentation GO:0035282 4 0.012
positive regulation of developmental process GO:0051094 314 0.012
jnk cascade GO:0007254 80 0.012
regulation of cytokine secretion involved in immune response GO:0002739 7 0.012
regulation of protein maturation GO:1903317 150 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
generation of neurons GO:0048699 152 0.011
regulation of protein binding GO:0043393 66 0.011
negative regulation of catabolic process GO:0009895 104 0.011
leukocyte mediated immunity GO:0002443 59 0.011
negative regulation of protein processing GO:0010955 142 0.011
multi organism metabolic process GO:0044033 41 0.011
nuclear division GO:0000280 128 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
negative regulation of proteolysis GO:0045861 132 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
regulation of proteasomal protein catabolic process GO:0061136 87 0.010
sensory organ development GO:0007423 52 0.010

ATG3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.040
musculoskeletal system disease DOID:17 223 0.016
connective tissue disease DOID:65 109 0.016
inherited metabolic disorder DOID:655 242 0.014
disease of cellular proliferation DOID:14566 174 0.011