Homo sapiens

71 known processes

WNK1

WNK lysine deficient protein kinase 1

(Aliases: KIAA0344,p65,PRKWNK1,PSK,MGC163341,MGC163339,HSN2,KDP,HSAN2)

WNK1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sodium ion transport GO:0006814 61 0.343
Human
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.311
Human
system process GO:0003008 349 0.297
Human Mouse
ion transmembrane transport GO:0034220 338 0.277
response to virus GO:0009615 126 0.225
sex determination GO:0007530 3 0.215
positive regulation of transporter activity GO:0032411 32 0.205
Human
cell development GO:0048468 328 0.192
Fly
cellular ketone metabolic process GO:0042180 80 0.192
metal ion transport GO:0030001 272 0.176
Human Rat
cation transport GO:0006812 331 0.164
Human Rat
vesicle mediated transport GO:0016192 371 0.158
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.150
response to salt stress GO:0009651 3 0.146
inorganic ion transmembrane transport GO:0098660 231 0.143
cellular lipid metabolic process GO:0044255 303 0.139
monocarboxylic acid metabolic process GO:0032787 185 0.138
rna processing GO:0006396 255 0.134
positive regulation of cellular amine metabolic process GO:0033240 7 0.130
small gtpase mediated signal transduction GO:0007264 78 0.130
negative regulation of programmed cell death GO:0043069 321 0.129
Human
monovalent inorganic cation transport GO:0015672 128 0.126
Human Rat
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.126
nucleoside catabolic process GO:0009164 408 0.120
positive regulation of ion transmembrane transport GO:0034767 40 0.117
Human
regulation of ion transmembrane transport GO:0034765 132 0.113
Human
negative regulation of apoptotic process GO:0043066 316 0.111
Human
cell morphogenesis GO:0000902 296 0.109
Fly
chromatin organization GO:0006325 351 0.103
fatty acid metabolic process GO:0006631 115 0.099
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.096
nucleoside triphosphate catabolic process GO:0009143 394 0.091
regulation of ion transmembrane transporter activity GO:0032412 72 0.090
Human
response to other organism GO:0051707 261 0.090
response to external biotic stimulus GO:0043207 261 0.090
regulation of cellular ketone metabolic process GO:0010565 50 0.088
determination of adult lifespan GO:0008340 2 0.088
cellular macromolecule catabolic process GO:0044265 380 0.087
nervous system development GO:0007399 293 0.086
Fly
regulation of sodium ion transmembrane transport GO:1902305 23 0.086
Human
lipid metabolic process GO:0006629 381 0.086
cytoplasmic transport GO:0016482 379 0.085
Human
cellular component morphogenesis GO:0032989 314 0.084
Fly
ion homeostasis GO:0050801 230 0.081
Human
endosomal transport GO:0016197 129 0.081
negative regulation of smoothened signaling pathway GO:0045879 3 0.081
cellular amino acid metabolic process GO:0006520 116 0.080
regulation of cytoskeleton organization GO:0051493 177 0.079
signal transduction by phosphorylation GO:0023014 297 0.079
Human
regulation of cell differentiation GO:0045595 393 0.078
single organism cellular localization GO:1902580 332 0.078
Human
negative regulation of blood pressure GO:0045776 3 0.077
positive regulation of catabolic process GO:0009896 310 0.075
positive regulation of transmembrane transport GO:0034764 41 0.075
Human
nucleotide catabolic process GO:0009166 408 0.073
response to abiotic stimulus GO:0009628 336 0.071
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.071
protein localization to organelle GO:0033365 280 0.070
cellular amine metabolic process GO:0044106 41 0.070
ras protein signal transduction GO:0007265 73 0.069
amine metabolic process GO:0009308 44 0.069
protein ubiquitination GO:0016567 314 0.069
gtp metabolic process GO:0046039 239 0.069
lipid biosynthetic process GO:0008610 177 0.068
chemical homeostasis GO:0048878 306 0.068
Human
actin filament based process GO:0030029 224 0.068
ribonucleoside triphosphate catabolic process GO:0009203 391 0.067
mitotic cell cycle GO:0000278 326 0.066
regulation of anatomical structure size GO:0090066 101 0.066
positive regulation of protein phosphorylation GO:0001934 313 0.065
Human
cell type specific apoptotic process GO:0097285 125 0.065
generation of neurons GO:0048699 152 0.065
Fly
receptor internalization GO:0031623 43 0.064
positive regulation of phosphorylation GO:0042327 394 0.064
Human
positive regulation of cellular component organization GO:0051130 376 0.064
Human
cell fate determination GO:0001709 3 0.063
regulation of protein transport GO:0051223 213 0.063
somatic muscle development GO:0007525 1 0.062
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.062
oogenesis GO:0048477 2 0.061
response to biotic stimulus GO:0009607 276 0.061
neurological system process GO:0050877 163 0.061
organic acid biosynthetic process GO:0016053 97 0.060
coenzyme metabolic process GO:0006732 65 0.059
regulation of cellular amine metabolic process GO:0033238 11 0.059
purine ribonucleotide catabolic process GO:0009154 404 0.059
positive regulation of cellular catabolic process GO:0031331 284 0.059
purine nucleotide catabolic process GO:0006195 405 0.059
endocytosis GO:0006897 159 0.059
protein catabolic process GO:0030163 325 0.058
nucleoside triphosphate metabolic process GO:0009141 422 0.058
defense response to virus GO:0051607 71 0.058
regulation of potassium ion transmembrane transport GO:1901379 20 0.057
cell projection organization GO:0030030 252 0.056
Fly
negative regulation of catalytic activity GO:0043086 335 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.055
cellular protein catabolic process GO:0044257 261 0.055
negative regulation of cellular protein metabolic process GO:0032269 353 0.055
Rat
protein modification by small protein conjugation GO:0032446 342 0.054
cofactor biosynthetic process GO:0051188 31 0.054
myoblast fusion GO:0007520 1 0.054
negative regulation of cellular component organization GO:0051129 235 0.052
purine nucleoside triphosphate metabolic process GO:0009144 412 0.051
transmembrane transport GO:0055085 399 0.051
regulation of ion homeostasis GO:2000021 73 0.051
Human
cellular potassium ion transport GO:0071804 60 0.051
Rat
guanosine containing compound metabolic process GO:1901068 244 0.051
negative regulation of systemic arterial blood pressure GO:0003085 1 0.050
microtubule cytoskeleton organization GO:0000226 176 0.050
ossification GO:0001503 121 0.050
regulation of protein catabolic process GO:0042176 155 0.049
establishment of ribosome localization GO:0033753 4 0.049
regulation of defense response GO:0031347 154 0.049
gtp catabolic process GO:0006184 237 0.049
negative regulation of cell proliferation GO:0008285 228 0.048
Human
proteasomal protein catabolic process GO:0010498 176 0.048
nuclear export GO:0051168 69 0.048
potassium ion transmembrane transport GO:0071805 60 0.048
Rat
reproductive process GO:0022414 106 0.047
Worm
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.047
circulatory system process GO:0003013 113 0.046
Mouse
intracellular protein transport GO:0006886 270 0.046
actin cytoskeleton organization GO:0030036 207 0.046
cellular response to abiotic stimulus GO:0071214 117 0.046
regulation of cell cycle GO:0051726 393 0.046
negative regulation of transport GO:0051051 176 0.045
Mouse
regulation of transmembrane transport GO:0034762 139 0.045
Human
regulation of small gtpase mediated signal transduction GO:0051056 156 0.045
potassium ion transport GO:0006813 62 0.045
Rat
positive regulation of developmental process GO:0051094 314 0.045
response to oxygen containing compound GO:1901700 369 0.045
regulation of cellular component biogenesis GO:0044087 281 0.045
regulation of purine nucleotide metabolic process GO:1900542 264 0.044
regulation of gtp catabolic process GO:0033124 180 0.044
regulation of transmembrane transporter activity GO:0022898 74 0.044
Human
interspecies interaction between organisms GO:0044419 156 0.044
positive regulation of sodium ion transport GO:0010765 14 0.044
Human
multi organism cellular process GO:0044764 156 0.044
positive regulation of ion transport GO:0043270 87 0.043
Human
organelle fission GO:0048285 149 0.043
regulation of ion transport GO:0043269 189 0.043
Human
regulation of nucleoside metabolic process GO:0009118 209 0.042
regulation of mapk cascade GO:0043408 262 0.042
Human
regulation of systemic arterial blood pressure GO:0003073 19 0.042
Mouse
nucleocytoplasmic transport GO:0006913 176 0.042
mapk cascade GO:0000165 288 0.042
Human
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.041
actin filament organization GO:0007015 128 0.041
regulation of proteasomal protein catabolic process GO:0061136 87 0.041
chromatin modification GO:0016568 298 0.041
regulation of ras protein signal transduction GO:0046578 155 0.041
organophosphate catabolic process GO:0046434 430 0.041
female sex determination GO:0030237 1 0.040
wnt signaling pathway GO:0016055 156 0.040
Fly
cofactor metabolic process GO:0051186 87 0.040
regulation of establishment of protein localization GO:0070201 242 0.040
Human
negative regulation of cell death GO:0060548 345 0.040
Human
mitotic cell cycle process GO:1903047 286 0.039
regulation of transporter activity GO:0032409 82 0.039
Human
negative regulation of protein metabolic process GO:0051248 391 0.039
Rat
small molecule biosynthetic process GO:0044283 157 0.039
modification dependent protein catabolic process GO:0019941 209 0.039
modification dependent macromolecule catabolic process GO:0043632 212 0.039
guanosine containing compound catabolic process GO:1901069 239 0.038
regulation of nucleotide catabolic process GO:0030811 205 0.038
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
regulation of gtpase activity GO:0043087 180 0.038
regulation of proteolysis GO:0030162 293 0.037
regulation of multi organism process GO:0043900 157 0.037
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.037
covalent chromatin modification GO:0016569 254 0.037
intracellular receptor signaling pathway GO:0030522 104 0.037
regulation of sodium ion transmembrane transporter activity GO:2000649 17 0.036
Human
establishment of protein localization to organelle GO:0072594 172 0.036
positive regulation of ras gtpase activity GO:0032320 117 0.036
post embryonic development GO:0009791 2 0.036
anatomical structure formation involved in morphogenesis GO:0048646 284 0.036
ubiquitin dependent protein catabolic process GO:0006511 206 0.036
negative regulation of immune system process GO:0002683 136 0.036
canonical wnt signaling pathway GO:0060070 116 0.036
Fly
nuclear transport GO:0051169 179 0.036
protein k48 linked ubiquitination GO:0070936 38 0.036
viral process GO:0016032 146 0.036
steroid metabolic process GO:0008202 94 0.036
negative regulation of protein transport GO:0051224 75 0.035
positive regulation of hydrolase activity GO:0051345 331 0.035
neurogenesis GO:0022008 169 0.035
Fly
renal sodium ion absorption GO:0070294 2 0.035
Human
syncytium formation by plasma membrane fusion GO:0000768 2 0.035
segmentation GO:0035282 4 0.035
cell morphogenesis involved in differentiation GO:0000904 144 0.035
Fly
cellular macromolecular complex assembly GO:0034622 324 0.035
regulation of purine nucleotide catabolic process GO:0033121 205 0.035
regulation of membrane potential GO:0042391 95 0.034
cellular response to oxygen containing compound GO:1901701 276 0.034
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.034
female gamete generation GO:0007292 2 0.034
regulation of intracellular transport GO:0032386 195 0.034
positive regulation of cell death GO:0010942 263 0.034
monocarboxylic acid biosynthetic process GO:0072330 67 0.034
late endosome to vacuole transport GO:0045324 2 0.034
positive regulation of gtpase activity GO:0043547 166 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.033
regulation of metal ion transport GO:0010959 120 0.033
Human
regulation of cell cycle process GO:0010564 266 0.033
compound eye development GO:0048749 1 0.033
glycosyl compound catabolic process GO:1901658 413 0.033
immune effector process GO:0002252 159 0.033
muscle structure development GO:0061061 98 0.033
alcohol metabolic process GO:0006066 114 0.033
establishment of organelle localization GO:0051656 59 0.033
positive regulation of nucleotide metabolic process GO:0045981 230 0.033
positive regulation of programmed cell death GO:0043068 249 0.032
carboxylic acid biosynthetic process GO:0046394 97 0.032
regulation of actin cytoskeleton organization GO:0032956 116 0.032
positive regulation of gtp catabolic process GO:0033126 166 0.032
blastoderm segmentation GO:0007350 2 0.031
defense response GO:0006952 315 0.031
neuron projection development GO:0031175 106 0.031
Fly
associative learning GO:0008306 1 0.031
positive regulation of nucleotide catabolic process GO:0030813 185 0.031
autophagy GO:0006914 88 0.031
behavior GO:0007610 112 0.031
Worm
regulation of kinase activity GO:0043549 314 0.031
Rat
purine containing compound catabolic process GO:0072523 411 0.031
regulation of canonical wnt signaling pathway GO:0060828 88 0.031
Fly
skin development GO:0043588 76 0.031
regulation of response to external stimulus GO:0032101 222 0.030
negative regulation of organelle organization GO:0010639 126 0.030
neuromuscular junction development GO:0007528 3 0.030
microtubule based process GO:0007017 210 0.029
positive regulation of apoptotic process GO:0043065 246 0.029
positive regulation of mapk cascade GO:0043410 190 0.029
epithelial cell differentiation GO:0030855 141 0.029
protein acetylation GO:0006473 116 0.029
anterior posterior axis specification GO:0009948 2 0.029
regulation of lipid metabolic process GO:0019216 96 0.029
histone modification GO:0016570 251 0.029
neuroblast proliferation GO:0007405 4 0.029
nitrogen compound transport GO:0071705 191 0.029
regulation of vesicle mediated transport GO:0060627 130 0.029
osteoblast differentiation GO:0001649 92 0.028
cation transmembrane transport GO:0098655 238 0.028
Human Rat
epidermal cell differentiation GO:0009913 45 0.028
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.028
positive regulation of protein catabolic process GO:0045732 75 0.028
regulation of defense response to virus GO:0050688 33 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.027
regulation of ras gtpase activity GO:0032318 128 0.027
positive regulation of cell differentiation GO:0045597 211 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.027
ncrna metabolic process GO:0034660 108 0.027
locomotory behavior GO:0007626 1 0.027
multicellular organismal aging GO:0010259 3 0.027
protein monoubiquitination GO:0006513 39 0.027
regulation of protein localization GO:0032880 296 0.027
Human
protein autoubiquitination GO:0051865 37 0.027
negative regulation of phosphorylation GO:0042326 174 0.027
Human Rat
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.027
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.027
regulation of homeostatic process GO:0032844 121 0.027
Human
regulation of cellular protein catabolic process GO:1903362 96 0.027
regulation of receptor mediated endocytosis GO:0048259 32 0.026
regeneration GO:0031099 4 0.026
ribonucleoside triphosphate metabolic process GO:0009199 412 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
regulation of isoprenoid metabolic process GO:0019747 1 0.026
bmp signaling pathway GO:0030509 49 0.026
regulation of immune effector process GO:0002697 91 0.026
negative regulation of ion transmembrane transport GO:0034766 26 0.026
positive regulation of transport GO:0051050 336 0.026
Human
ribonucleoside catabolic process GO:0042454 406 0.026
negative regulation of hydrolase activity GO:0051346 182 0.026
positive regulation of cell proliferation GO:0008284 301 0.025
organic hydroxy compound biosynthetic process GO:1901617 71 0.025
chromatin assembly or disassembly GO:0006333 78 0.025
positive regulation of proteolysis GO:0045862 142 0.025
regulation of growth GO:0040008 165 0.025
regulation of actin filament based process GO:0032970 141 0.025
cellular response to endogenous stimulus GO:0071495 336 0.025
positive regulation of intracellular transport GO:0032388 104 0.025
receptor mediated endocytosis GO:0006898 84 0.025
cellular response to nitrogen compound GO:1901699 144 0.025
negative regulation of intracellular signal transduction GO:1902532 183 0.025
Human
forebrain generation of neurons GO:0021872 3 0.025
purine ribonucleoside catabolic process GO:0046130 398 0.025
hindbrain development GO:0030902 3 0.025
embryo development GO:0009790 123 0.024
regulation of cell morphogenesis GO:0022604 153 0.024
sensory perception of pain GO:0019233 4 0.024
cell projection morphogenesis GO:0048858 129 0.024
Fly
fatty acid biosynthetic process GO:0006633 46 0.024
regulation of locomotion GO:0040012 329 0.024
renal sodium ion transport GO:0003096 2 0.024
Human
positive regulation of cytoplasmic transport GO:1903651 82 0.024
regulation of membrane repolarization GO:0060306 16 0.024
rhythmic behavior GO:0007622 2 0.024
oocyte development GO:0048599 1 0.024
regulation of cell development GO:0060284 161 0.024
regulation of transferase activity GO:0051338 355 0.024
Rat
nucleoside monophosphate catabolic process GO:0009125 159 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
negative regulation of developmental process GO:0051093 247 0.023
regulation of cellular component size GO:0032535 82 0.023
regulation of protein kinase activity GO:0045859 289 0.023
Rat
endomembrane system organization GO:0010256 196 0.023
Human
regulation of blood pressure GO:0008217 30 0.023
Mouse
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.023
response to light stimulus GO:0009416 87 0.023
nucleobase containing compound transport GO:0015931 51 0.022
regulation of ribosome biogenesis GO:0090069 1 0.022
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.022
memory GO:0007613 3 0.022
receptor metabolic process GO:0043112 81 0.022
steroid biosynthetic process GO:0006694 46 0.022
cell adhesion GO:0007155 325 0.022
inositol lipid mediated signaling GO:0048017 55 0.022
ncrna processing GO:0034470 83 0.022
negative regulation of response to external stimulus GO:0032102 83 0.022
ribonucleoprotein complex biogenesis GO:0022613 116 0.022
spermatid differentiation GO:0048515 4 0.022
protein autophosphorylation GO:0046777 123 0.022
Human Rat Fly
distal tubule development GO:0072017 4 0.021
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
rho protein signal transduction GO:0007266 26 0.021
regulation of endocytosis GO:0030100 72 0.021
growth GO:0040007 202 0.021
ribonucleotide catabolic process GO:0009261 405 0.021
response to growth factor GO:0070848 205 0.021
regulation of cytoplasmic transport GO:1903649 149 0.021
sensory perception GO:0007600 103 0.021
peptidyl lysine modification GO:0018205 144 0.021
positive regulation of endocytosis GO:0045807 42 0.021
atp catabolic process GO:0006200 157 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
epithelial tube morphogenesis GO:0060562 38 0.021
Human
atp metabolic process GO:0046034 176 0.021
kidney morphogenesis GO:0060993 19 0.021
Human
epidermis development GO:0008544 59 0.020
positive regulation of protein kinase activity GO:0045860 190 0.020
regulation of potassium ion transport GO:0043266 24 0.020
enzyme linked receptor protein signaling pathway GO:0007167 303 0.020
defense response to other organism GO:0098542 129 0.020
photoreceptor cell differentiation GO:0046530 2 0.020
sterol metabolic process GO:0016125 28 0.020
adult locomotory behavior GO:0008344 1 0.020
regulation of nucleocytoplasmic transport GO:0046822 98 0.020
rna transport GO:0050658 39 0.020
interaction with host GO:0051701 42 0.020
positive regulation of cell migration GO:0030335 172 0.020
regulation of endosome size GO:0051036 3 0.020
inorganic cation transmembrane transport GO:0098662 194 0.020
Human Rat
drinking behavior GO:0042756 1 0.020
regulation of feeding behavior GO:0060259 3 0.019
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.019
oocyte differentiation GO:0009994 2 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
establishment of protein localization to membrane GO:0090150 121 0.019
Human
circadian behavior GO:0048512 2 0.019
rubidium ion transport GO:0035826 4 0.019
Human
protein localization to membrane GO:0072657 160 0.019
Human
neuron differentiation GO:0030182 138 0.019
Fly
negative regulation of defense response GO:0031348 47 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
membrane organization GO:0061024 292 0.019
Human
dna replication GO:0006260 116 0.019
chemotaxis GO:0006935 157 0.018
Fly
positive regulation of smoothened signaling pathway GO:0045880 4 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
angiogenesis GO:0001525 147 0.018
regulation of synaptic plasticity GO:0048167 3 0.018
positive regulation of kinase activity GO:0033674 204 0.018
negative regulation of ion transport GO:0043271 39 0.018
protein export from nucleus GO:0006611 29 0.018
metal ion homeostasis GO:0055065 169 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
regulation of cofactor metabolic process GO:0051193 3 0.018
nuclear division GO:0000280 128 0.018
establishment of rna localization GO:0051236 39 0.018
negative regulation of protein modification process GO:0031400 200 0.018
Rat
peripheral nervous system development GO:0007422 2 0.018
central nervous system development GO:0007417 123 0.018
phosphatidylinositol mediated signaling GO:0048015 55 0.018
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.018
cell part morphogenesis GO:0032990 137 0.018
Fly
negative regulation of transmembrane transport GO:0034763 29 0.018
cell growth GO:0016049 160 0.017
g protein coupled receptor signaling pathway GO:0007186 207 0.017
divalent inorganic cation transport GO:0072511 158 0.017
Human
regulation of cellular response to stress GO:0080135 244 0.017
muscle organ development GO:0007517 56 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.017
cell cell junction organization GO:0045216 69 0.017
sodium ion transmembrane transport GO:0035725 59 0.017
Human
response to wounding GO:0009611 168 0.017
ribonucleoside monophosphate catabolic process GO:0009158 158 0.017
stem cell differentiation GO:0048863 93 0.017
nucleoside monophosphate metabolic process GO:0009123 191 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
cell junction assembly GO:0034329 67 0.017
coenzyme biosynthetic process GO:0009108 24 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.017
somatic stem cell maintenance GO:0035019 4 0.017
cytokine production GO:0001816 247 0.017
regulation of cell division GO:0051302 116 0.017
cellular protein complex assembly GO:0043623 188 0.017
organelle assembly GO:0070925 176 0.017
maintenance of location GO:0051235 112 0.017
single organism membrane organization GO:0044802 268 0.017
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.017
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.016
negative regulation of multi organism process GO:0043901 92 0.016
metencephalon development GO:0022037 2 0.016
histone acetylation GO:0016573 93 0.016
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.016
alcohol biosynthetic process GO:0046165 52 0.016
demethylation GO:0070988 37 0.016
golgi vesicle transport GO:0048193 80 0.016
Human
regulation of cation channel activity GO:2001257 33 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.016
ribosome biogenesis GO:0042254 48 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.016
Fly
peptidyl threonine modification GO:0018210 45 0.016
Human
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.016
tripartite regional subdivision GO:0007351 2 0.016
response to inorganic substance GO:0010035 127 0.016
regulation of cell growth GO:0001558 135 0.016
response to nitrogen compound GO:1901698 184 0.016
response to uv GO:0009411 73 0.016
reproduction GO:0000003 63 0.016
Worm
regulation of nervous system development GO:0051960 88 0.016
motor neuron axon guidance GO:0008045 2 0.016
negative regulation of potassium ion transmembrane transport GO:1901380 5 0.016
negative regulation of catabolic process GO:0009895 104 0.016
protein k63 linked ubiquitination GO:0070534 31 0.016
muscle tissue development GO:0060537 62 0.016
positive regulation of dna metabolic process GO:0051054 73 0.016
cardiovascular system development GO:0072358 262 0.016
ribosome localization GO:0033750 4 0.015
negative regulation of sodium ion transmembrane transporter activity GO:2000650 2 0.015
ribosomal subunit export from nucleus GO:0000054 4 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
negative regulation of cell cycle GO:0045786 193 0.015
distal tubule morphogenesis GO:0072156 3 0.015
Human
multicellular organismal reproductive process GO:0048609 40 0.015
Worm
mitotic cell cycle phase transition GO:0044772 162 0.015
activation of protein kinase activity GO:0032147 90 0.015
epithelium development GO:0060429 227 0.015
Human
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.015
secretion by cell GO:0032940 226 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
Rat
negative regulation of sodium ion transport GO:0010766 3 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
positive regulation of cellular protein catabolic process GO:1903364 37 0.015
regulation of sodium ion transport GO:0002028 24 0.015
Human
long term memory GO:0007616 2 0.015
cell junction organization GO:0034330 79 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.015
limbic system development GO:0021761 3 0.015
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.015
cell division GO:0051301 168 0.015
protein maturation GO:0051604 233 0.015
cellular response to radiation GO:0071478 65 0.015
organophosphate biosynthetic process GO:0090407 163 0.014
plasma membrane organization GO:0007009 115 0.014
Human
divalent metal ion transport GO:0070838 152 0.014
Human
tissue morphogenesis GO:0048729 96 0.014
Human
response to metal ion GO:0010038 84 0.014
cellular response to organonitrogen compound GO:0071417 124 0.014
regulation of microtubule based process GO:0032886 74 0.014
negative regulation of transporter activity GO:0032410 25 0.014
positive regulation of lipid metabolic process GO:0045834 50 0.014
response to transforming growth factor beta GO:0071559 94 0.014
regulation of protein maturation GO:1903317 150 0.014
multi organism reproductive process GO:0044703 54 0.014
Worm
internal protein amino acid acetylation GO:0006475 101 0.014
regulation of neurogenesis GO:0050767 82 0.014
positive regulation of lipid biosynthetic process GO:0046889 22 0.014
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.014
protein acylation GO:0043543 138 0.014
brain development GO:0007420 97 0.014
regulation of dephosphorylation GO:0035303 96 0.014
trna metabolic process GO:0006399 35 0.014

WNK1 disease predictions

Disease DO term ID Size Probability Func Analog Org
renal tubular transport disease DOID:447 11 0.018
kidney disease DOID:557 36 0.018
urinary system disease DOID:18 40 0.018
sensory system disease DOID:0050155 203 0.015
nervous system disease DOID:863 431 0.015
disease of metabolism DOID:0014667 295 0.014