Homo sapiens

6 known processes

DBT

dihydrolipoamide branched chain transacylase E2

(Aliases: BCATE2,MGC9061,E2B,E2)

DBT biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.138
translation GO:0006412 132 0.098
sulfur compound metabolic process GO:0006790 101 0.090
post embryonic development GO:0009791 2 0.060
sulfur compound biosynthetic process GO:0044272 38 0.054
determination of adult lifespan GO:0008340 2 0.049
negative regulation of cellular protein metabolic process GO:0032269 353 0.049
negative regulation of protein metabolic process GO:0051248 391 0.048
regulation of translation GO:0006417 89 0.047
multicellular organismal aging GO:0010259 3 0.045
lipid metabolic process GO:0006629 381 0.044
posttranscriptional regulation of gene expression GO:0010608 213 0.043
cellular lipid metabolic process GO:0044255 303 0.043
chromatin organization GO:0006325 351 0.039
protein deubiquitination GO:0016579 79 0.038
negative regulation of apoptotic process GO:0043066 316 0.038
cellular macromolecule catabolic process GO:0044265 380 0.035
locomotory behavior GO:0007626 1 0.035
organonitrogen compound biosynthetic process GO:1901566 200 0.035
histone modification GO:0016570 251 0.034
negative regulation of cell death GO:0060548 345 0.033
cellular amino acid biosynthetic process GO:0008652 30 0.033
cellular amine metabolic process GO:0044106 41 0.032
cofactor metabolic process GO:0051186 87 0.032
chromatin modification GO:0016568 298 0.032
cellular response to dna damage stimulus GO:0006974 379 0.031
mitotic cell cycle GO:0000278 326 0.030
negative regulation of programmed cell death GO:0043069 321 0.030
purine nucleoside triphosphate catabolic process GO:0009146 392 0.029
purine ribonucleoside metabolic process GO:0046128 437 0.029
single organism cellular localization GO:1902580 332 0.029
positive regulation of catabolic process GO:0009896 310 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
coenzyme metabolic process GO:0006732 65 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
amine metabolic process GO:0009308 44 0.028
ribonucleotide catabolic process GO:0009261 405 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.027
purine nucleotide catabolic process GO:0006195 405 0.026
organic acid biosynthetic process GO:0016053 97 0.026
protein modification by small protein removal GO:0070646 92 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
monocarboxylic acid metabolic process GO:0032787 185 0.025
nucleotide catabolic process GO:0009166 408 0.025
cellular response to nitrogen compound GO:1901699 144 0.024
covalent chromatin modification GO:0016569 254 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
alpha amino acid metabolic process GO:1901605 72 0.024
positive regulation of hydrolase activity GO:0051345 331 0.023
cellular ketone metabolic process GO:0042180 80 0.023
response to oxygen containing compound GO:1901700 369 0.023
hindbrain development GO:0030902 3 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
response to organic cyclic compound GO:0014070 204 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
neuromuscular junction development GO:0007528 3 0.021
nucleoside catabolic process GO:0009164 408 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
membrane organization GO:0061024 292 0.021
purine nucleoside catabolic process GO:0006152 398 0.020
response to abiotic stimulus GO:0009628 336 0.020
female gamete generation GO:0007292 2 0.020
regulation of cell cycle process GO:0010564 266 0.020
mitotic cell cycle process GO:1903047 286 0.020
ncrna metabolic process GO:0034660 108 0.020
spermatid development GO:0007286 4 0.019
protein oligomerization GO:0051259 173 0.019
purine containing compound catabolic process GO:0072523 411 0.019
carboxylic acid biosynthetic process GO:0046394 97 0.019
small gtpase mediated signal transduction GO:0007264 78 0.019
oogenesis GO:0048477 2 0.019
single organism membrane organization GO:0044802 268 0.019
cellular protein catabolic process GO:0044257 261 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
regulation of cellular response to stress GO:0080135 244 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
protein catabolic process GO:0030163 325 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
regulation of locomotion GO:0040012 329 0.018
organophosphate catabolic process GO:0046434 430 0.018
response to nitrogen compound GO:1901698 184 0.017
regulation of cellular component movement GO:0051270 334 0.017
ras protein signal transduction GO:0007265 73 0.017
cell type specific apoptotic process GO:0097285 125 0.017
positive regulation of developmental process GO:0051094 314 0.017
cellular component morphogenesis GO:0032989 314 0.017
ion homeostasis GO:0050801 230 0.017
cation transport GO:0006812 331 0.017
regulation of response to external stimulus GO:0032101 222 0.017
cytoplasmic transport GO:0016482 379 0.017
spermatid differentiation GO:0048515 4 0.017
protein homooligomerization GO:0051260 100 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
cell morphogenesis GO:0000902 296 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.016
oxidation reduction process GO:0055114 396 0.016
memory GO:0007613 3 0.016
cell adhesion GO:0007155 325 0.016
cellular response to organic cyclic compound GO:0071407 127 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
guanosine containing compound metabolic process GO:1901068 244 0.016
ion transmembrane transport GO:0034220 338 0.016
gtp catabolic process GO:0006184 237 0.016
adult locomotory behavior GO:0008344 1 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
mitochondrion organization GO:0007005 156 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
regulation of proteolysis GO:0030162 293 0.015
regulation of protein localization GO:0032880 296 0.015
organelle fission GO:0048285 149 0.015
gtp metabolic process GO:0046039 239 0.015
mrna metabolic process GO:0016071 175 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
transmembrane transport GO:0055085 399 0.015
intracellular protein transport GO:0006886 270 0.015
alpha amino acid biosynthetic process GO:1901607 23 0.015
regulation of cell motility GO:2000145 299 0.015
regulation of transferase activity GO:0051338 355 0.015
nervous system development GO:0007399 293 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
cell development GO:0048468 328 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
apoptotic signaling pathway GO:0097190 268 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
translational initiation GO:0006413 48 0.014
rna processing GO:0006396 255 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
anterior posterior axis specification GO:0009948 2 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
protein k63 linked deubiquitination GO:0070536 21 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
protein localization to organelle GO:0033365 280 0.014
chemical homeostasis GO:0048878 306 0.014
small molecule catabolic process GO:0044282 92 0.014
immune response GO:0006955 307 0.014
lipid biosynthetic process GO:0008610 177 0.014
protein processing GO:0016485 226 0.014
cation transmembrane transport GO:0098655 238 0.014
negative regulation of cell cycle GO:0045786 193 0.014
organic acid catabolic process GO:0016054 71 0.014
rho protein signal transduction GO:0007266 26 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
positive regulation of transport GO:0051050 336 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.013
regulation of growth GO:0040008 165 0.013
negative regulation of developmental process GO:0051093 247 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
biological adhesion GO:0022610 331 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
segmentation GO:0035282 4 0.013
regulation of protein transport GO:0051223 213 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
regulation of cell migration GO:0030334 289 0.013
mapk cascade GO:0000165 288 0.013
regulation of kinase activity GO:0043549 314 0.013
metal ion transport GO:0030001 272 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
cell growth GO:0016049 160 0.013
regulation of protein kinase activity GO:0045859 289 0.013
maintenance of location GO:0051235 112 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
secretion by cell GO:0032940 226 0.012
system process GO:0003008 349 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
defense response GO:0006952 315 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
carbohydrate metabolic process GO:0005975 207 0.012
cell projection assembly GO:0030031 126 0.012
microtubule based process GO:0007017 210 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
actin filament based process GO:0030029 224 0.012
cell projection organization GO:0030030 252 0.012
fatty acid metabolic process GO:0006631 115 0.012
negative regulation of protein modification process GO:0031400 200 0.012
cation homeostasis GO:0055080 189 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
sensory perception of smell GO:0007608 2 0.012
cellular cation homeostasis GO:0030003 163 0.012
regulation of gtpase activity GO:0043087 180 0.012
dephosphorylation GO:0016311 209 0.012
positive regulation of cell death GO:0010942 263 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
peripheral nervous system development GO:0007422 2 0.012
negative regulation of phosphorylation GO:0042326 174 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
negative regulation of transferase activity GO:0051348 124 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
mitotic nuclear division GO:0007067 119 0.011
regeneration GO:0031099 4 0.011
neurological system process GO:0050877 163 0.011
response to biotic stimulus GO:0009607 276 0.011
rna interference GO:0016246 4 0.011
regulation of secretion GO:0051046 194 0.011
cellular protein complex assembly GO:0043623 188 0.011
regulation of cytokine production GO:0001817 232 0.011
response to nutrient levels GO:0031667 81 0.011
vesicle mediated transport GO:0016192 371 0.011
Fly
somitogenesis GO:0001756 2 0.011
cellular homeostasis GO:0019725 196 0.011
regulation of multi organism process GO:0043900 157 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
protein maturation GO:0051604 233 0.011
protein ubiquitination GO:0016567 314 0.011
regulation of intracellular transport GO:0032386 195 0.011
rhythmic behavior GO:0007622 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
response to growth factor GO:0070848 205 0.011
mrna processing GO:0006397 133 0.011
metal ion homeostasis GO:0055065 169 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
methylation GO:0032259 106 0.011
small molecule biosynthetic process GO:0044283 157 0.011
atp metabolic process GO:0046034 176 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
innate immune response GO:0045087 178 0.011
tube development GO:0035295 125 0.011
regulation of secretion by cell GO:1903530 177 0.011
regulation of cell growth GO:0001558 135 0.010
protein acylation GO:0043543 138 0.010
hemopoiesis GO:0030097 180 0.010
regulation of peptidase activity GO:0052547 180 0.010
positive regulation of organelle organization GO:0010638 195 0.010
cytokine production GO:0001816 247 0.010
regulation of membrane potential GO:0042391 95 0.010
nuclear transport GO:0051169 179 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
positive regulation of cellular component movement GO:0051272 181 0.010
cellular response to external stimulus GO:0071496 111 0.010
nuclear division GO:0000280 128 0.010
regulation of binding GO:0051098 111 0.010
metencephalon development GO:0022037 2 0.010
embryonic epithelial tube formation GO:0001838 4 0.010
positive regulation of immune system process GO:0002684 283 0.010
cilium assembly GO:0042384 63 0.010
monovalent inorganic cation transport GO:0015672 128 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
negative regulation of blood pressure GO:0045776 3 0.010
sequestering of metal ion GO:0051238 24 0.010

DBT disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.084
inherited metabolic disorder DOID:655 242 0.084
amino acid metabolic disorder DOID:9252 50 0.054
sensory system disease DOID:0050155 203 0.021
nervous system disease DOID:863 431 0.021
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.016
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
retinal disease DOID:5679 118 0.015
musculoskeletal system disease DOID:17 223 0.015
central nervous system disease DOID:331 186 0.014
organ system cancer DOID:0050686 164 0.013
immune system disease DOID:2914 155 0.013
muscular disease DOID:0080000 114 0.012
cardiovascular system disease DOID:1287 106 0.011
organic acidemia DOID:0060159 14 0.006
maple syrup urine disease DOID:9269 5 0.002