Homo sapiens

66 known processes

MED6

mediator complex subunit 6

(Aliases: NY-REN-28)

MED6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.859
stem cell differentiation GO:0048863 93 0.797
negative regulation of cell differentiation GO:0045596 171 0.602
Fly
post embryonic development GO:0009791 2 0.584
Worm
dna integrity checkpoint GO:0031570 71 0.466
neuroblast proliferation GO:0007405 4 0.445
Fly
rna processing GO:0006396 255 0.419
rna 3 end processing GO:0031123 35 0.370
negative regulation of developmental process GO:0051093 247 0.348
Worm Fly
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.295
dna templated transcription initiation GO:0006352 35 0.260
oogenesis GO:0048477 2 0.253
Worm
regulation of cell cycle GO:0051726 393 0.245
stem cell development GO:0048864 69 0.243
negative regulation of cell proliferation GO:0008285 228 0.230
Fly
intracellular receptor signaling pathway GO:0030522 104 0.207
cellular macromolecule catabolic process GO:0044265 380 0.187
nervous system development GO:0007399 293 0.180
Fly
blastocyst development GO:0001824 3 0.172
regulation of neural precursor cell proliferation GO:2000177 4 0.164
Fly
female gamete generation GO:0007292 2 0.162
Worm
androgen receptor signaling pathway GO:0030521 34 0.154
negative regulation of cell cycle phase transition GO:1901988 89 0.146
regulation of meiotic cell cycle GO:0051445 4 0.133
embryo development GO:0009790 123 0.127
Worm
determination of adult lifespan GO:0008340 2 0.125
regulation of cell cycle process GO:0010564 266 0.121
cell development GO:0048468 328 0.110
Worm Fly
dna damage checkpoint GO:0000077 68 0.109
cellular ketone metabolic process GO:0042180 80 0.106
single organism cellular localization GO:1902580 332 0.092
regulation of cellular ketone metabolic process GO:0010565 50 0.090
response to growth factor GO:0070848 205 0.088
cellular component morphogenesis GO:0032989 314 0.087
lipid biosynthetic process GO:0008610 177 0.087
cellular response to growth factor stimulus GO:0071363 197 0.081
negative regulation of multicellular organismal process GO:0051241 317 0.079
Worm Fly
cell cycle phase transition GO:0044770 173 0.078
cellular response to endogenous stimulus GO:0071495 336 0.076
multicellular organismal aging GO:0010259 3 0.074
stem cell division GO:0017145 2 0.074
mitotic cell cycle process GO:1903047 286 0.070
regulation of mitotic cell cycle phase transition GO:1901990 118 0.069
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.067
mitotic cell cycle phase transition GO:0044772 162 0.065
growth GO:0040007 202 0.063
single organism reproductive process GO:0044702 98 0.059
Worm
negative regulation of cell cycle process GO:0010948 121 0.059
regulation of transferase activity GO:0051338 355 0.059
regulation of growth GO:0040008 165 0.059
developmental process involved in reproduction GO:0003006 66 0.059
Worm
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.059
neurogenesis GO:0022008 169 0.058
Fly
cellular response to thyroid hormone stimulus GO:0097067 9 0.057
regulation of mitotic cell cycle GO:0007346 189 0.056
multicellular organismal reproductive process GO:0048609 40 0.053
Worm
regulation of neuroblast proliferation GO:1902692 3 0.053
Fly
single organism cell adhesion GO:0098602 179 0.052
regeneration GO:0031099 4 0.052
negative regulation of programmed cell death GO:0043069 321 0.051
ncrna metabolic process GO:0034660 108 0.049
regulation of cellular amine metabolic process GO:0033238 11 0.049
nucleocytoplasmic transport GO:0006913 176 0.049
ncrna processing GO:0034470 83 0.049
positive regulation of cell proliferation GO:0008284 301 0.047
regulation of cell differentiation GO:0045595 393 0.047
Fly
dna conformation change GO:0071103 113 0.046
generation of neurons GO:0048699 152 0.045
Fly
g2 dna damage checkpoint GO:0031572 26 0.044
vesicle mediated transport GO:0016192 371 0.044
thyroid hormone metabolic process GO:0042403 4 0.043
regulation of protein transport GO:0051223 213 0.042
regulation of intracellular transport GO:0032386 195 0.041
negative regulation of cellular component organization GO:0051129 235 0.041
intracellular protein transport GO:0006886 270 0.041
lipid metabolic process GO:0006629 381 0.040
negative regulation of cell cycle GO:0045786 193 0.039
cellular response to nutrient levels GO:0031669 69 0.039
nitrogen compound transport GO:0071705 191 0.038
regulation of cell cycle phase transition GO:1901987 126 0.037
vitamin d receptor signaling pathway GO:0070561 4 0.036
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.036
regulation of neurogenesis GO:0050767 82 0.036
Fly
regulation of kinase activity GO:0043549 314 0.036
positive regulation of growth GO:0045927 58 0.036
mitotic dna damage checkpoint GO:0044773 28 0.035
mitotic cell cycle GO:0000278 326 0.034
regulation of protein kinase activity GO:0045859 289 0.034
regulation of protein localization GO:0032880 296 0.034
photoreceptor cell differentiation GO:0046530 2 0.034
neuromuscular junction development GO:0007528 3 0.034
chromatin assembly or disassembly GO:0006333 78 0.034
cellular macromolecular complex assembly GO:0034622 324 0.033
nuclear transport GO:0051169 179 0.032
ncrna 3 end processing GO:0043628 4 0.031
embryo development ending in birth or egg hatching GO:0009792 34 0.031
Worm
regulation of meiosis GO:0040020 3 0.030
regulation of cell development GO:0060284 161 0.030
Fly
mrna metabolic process GO:0016071 175 0.030
stem cell maintenance GO:0019827 19 0.030
negative regulation of cell development GO:0010721 48 0.029
Fly
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 3 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.028
reproduction GO:0000003 63 0.028
Worm
cellular amino acid metabolic process GO:0006520 116 0.028
organic hydroxy compound metabolic process GO:1901615 147 0.028
enzyme linked receptor protein signaling pathway GO:0007167 303 0.027
multi organism cellular process GO:0044764 156 0.027
cellular response to dna damage stimulus GO:0006974 379 0.027
cellular hormone metabolic process GO:0034754 41 0.027
cell morphogenesis GO:0000902 296 0.027
cytoplasmic transport GO:0016482 379 0.026
reproductive structure development GO:0048608 55 0.026
Worm
cellular amine metabolic process GO:0044106 41 0.026
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
mitotic cell cycle checkpoint GO:0007093 68 0.025
response to fungus GO:0009620 4 0.025
meiotic chromosome segregation GO:0045132 4 0.025
small gtpase mediated signal transduction GO:0007264 78 0.024
negative regulation of protein metabolic process GO:0051248 391 0.024
cell projection morphogenesis GO:0048858 129 0.023
innate immune response GO:0045087 178 0.023
Fly
cellular protein complex assembly GO:0043623 188 0.023
protein targeting GO:0006605 187 0.023
mapk cascade GO:0000165 288 0.023
positive regulation of transport GO:0051050 336 0.022
interspecies interaction between organisms GO:0044419 156 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
positive regulation of protein transport GO:0051222 135 0.022
response to abiotic stimulus GO:0009628 336 0.021
snrna 3 end processing GO:0034472 1 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
developmental growth GO:0048589 48 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.021
response to other organism GO:0051707 261 0.021
Fly
regulation of cellular component biogenesis GO:0044087 281 0.021
ras protein signal transduction GO:0007265 73 0.021
regulation of nervous system development GO:0051960 88 0.020
Fly
protein localization to organelle GO:0033365 280 0.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.020
ribonucleotide catabolic process GO:0009261 405 0.020
development of primary sexual characteristics GO:0045137 35 0.020
Worm
biological adhesion GO:0022610 331 0.020
mitotic dna integrity checkpoint GO:0044774 30 0.020
regulation of transcription by galactose GO:0000409 1 0.020
viral process GO:0016032 146 0.020
actin filament based process GO:0030029 224 0.020
negative regulation of growth GO:0045926 97 0.019
protein dna complex assembly GO:0065004 64 0.019
response to biotic stimulus GO:0009607 276 0.019
Fly
spermatid development GO:0007286 4 0.019
ribonucleoprotein complex assembly GO:0022618 78 0.019
neuron projection development GO:0031175 106 0.019
protein processing GO:0016485 226 0.019
ribonucleoprotein complex subunit organization GO:0071826 81 0.019
striated muscle tissue development GO:0014706 59 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
response to external biotic stimulus GO:0043207 261 0.019
Fly
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
viral life cycle GO:0019058 132 0.018
neuron development GO:0048666 113 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
mrna splicing via spliceosome GO:0000398 89 0.018
locomotory behavior GO:0007626 1 0.018
positive regulation of immune system process GO:0002684 283 0.018
circulatory system development GO:0072359 262 0.018
organelle assembly GO:0070925 176 0.018
steroid biosynthetic process GO:0006694 46 0.018
negative regulation of kinase activity GO:0033673 106 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
negative regulation of neurogenesis GO:0050768 26 0.017
Fly
positive regulation of cellular component organization GO:0051130 376 0.017
regulation of protein targeting GO:1903533 91 0.017
reproductive system development GO:0061458 56 0.017
Worm
endocytosis GO:0006897 159 0.017
cell adhesion GO:0007155 325 0.017
oocyte differentiation GO:0009994 2 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
rna interference GO:0016246 4 0.017
protein maturation GO:0051604 233 0.017
organophosphate catabolic process GO:0046434 430 0.017
apoptotic signaling pathway GO:0097190 268 0.017
regulation of proteasomal protein catabolic process GO:0061136 87 0.016
regulation of membrane potential GO:0042391 95 0.016
alcohol metabolic process GO:0006066 114 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
positive regulation of intracellular transport GO:0032388 104 0.016
reproductive process GO:0022414 106 0.016
Worm
rna splicing GO:0008380 131 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
regulation of proteolysis GO:0030162 293 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.015
cellular lipid metabolic process GO:0044255 303 0.015
mrna processing GO:0006397 133 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
lens development in camera type eye GO:0002088 2 0.015
cellular response to oxidative stress GO:0034599 85 0.015
positive regulation of catabolic process GO:0009896 310 0.015
regulation of hormone levels GO:0010817 125 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.014
regulation of epithelial cell proliferation GO:0050678 113 0.014
gtp metabolic process GO:0046039 239 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
regulation of cell cell adhesion GO:0022407 57 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
positive regulation of intracellular protein transport GO:0090316 76 0.014
sexual reproduction GO:0019953 37 0.014
Worm
regulation of intracellular protein transport GO:0033157 123 0.014
regulation of cytokine mediated signaling pathway GO:0001959 41 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
regulation of vitamin d receptor signaling pathway GO:0070562 3 0.013
positive regulation of developmental process GO:0051094 314 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
nucleosome assembly GO:0006334 50 0.013
segmentation GO:0035282 4 0.013
ribonucleoside triphosphate metabolic process GO:0009199 412 0.013
response to cytokine GO:0034097 232 0.013
response to organic cyclic compound GO:0014070 204 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
regulation of cell adhesion GO:0030155 166 0.013
small molecule biosynthetic process GO:0044283 157 0.013
positive regulation of dendrite morphogenesis GO:0050775 3 0.013
negative regulation of dna metabolic process GO:0051053 57 0.012
negative regulation of catalytic activity GO:0043086 335 0.012
positive regulation of transcription by galactose GO:0000411 1 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
ribonucleoprotein complex biogenesis GO:0022613 116 0.012
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
regulation of epithelial to mesenchymal transition GO:0010717 37 0.012
appendage morphogenesis GO:0035107 16 0.012
chromatin organization GO:0006325 351 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
tripartite regional subdivision GO:0007351 2 0.012
cell projection organization GO:0030030 252 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
regulation of multi organism process GO:0043900 157 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
epithelial cell proliferation GO:0050673 128 0.012
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
cell division GO:0051301 168 0.012
protein catabolic process GO:0030163 325 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
snrna metabolic process GO:0016073 15 0.012
chordate embryonic development GO:0043009 34 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
hindlimb morphogenesis GO:0035137 2 0.012
dna replication GO:0006260 116 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
regulation of peptidase activity GO:0052547 180 0.012
negative regulation of protein catabolic process GO:0042177 59 0.012
cell cycle checkpoint GO:0000075 117 0.012
nucleotide catabolic process GO:0009166 408 0.011
regulation of protein catabolic process GO:0042176 155 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
gonad development GO:0008406 34 0.011
Worm
positive regulation of organelle organization GO:0010638 195 0.011
regulation of mapk cascade GO:0043408 262 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.011
thyroid hormone generation GO:0006590 2 0.011
defense response to fungus GO:0050832 4 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
nucleoside catabolic process GO:0009164 408 0.011
axis elongation GO:0003401 4 0.011
nuclear division GO:0000280 128 0.011
central nervous system development GO:0007417 123 0.011
angiogenesis GO:0001525 147 0.011
positive regulation of cell death GO:0010942 263 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 3 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
fatty acid metabolic process GO:0006631 115 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
regulation of lipid metabolic process GO:0019216 96 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.010
system process GO:0003008 349 0.010
nuclear import GO:0051170 106 0.010
microtubule based process GO:0007017 210 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
negative regulation of protein modification process GO:0031400 200 0.010
regulation of cellular amino acid metabolic process GO:0006521 6 0.010
signal transduction by phosphorylation GO:0023014 297 0.010
response to interferon gamma GO:0034341 39 0.010
oocyte development GO:0048599 1 0.010
proteasomal protein catabolic process GO:0010498 176 0.010
negative regulation of epithelial cell proliferation GO:0050680 48 0.010
monocarboxylic acid metabolic process GO:0032787 185 0.010
branch elongation of an epithelium GO:0060602 3 0.010
protein oligomerization GO:0051259 173 0.010
establishment of ribosome localization GO:0033753 4 0.010

MED6 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.023
eye and adnexa disease DOID:1492 150 0.023
nervous system disease DOID:863 431 0.023
eye disease DOID:5614 149 0.015