Homo sapiens

0 known processes

MED8

mediator complex subunit 8

(Aliases: MGC17544,MGC19641,ARC32)

MED8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.200
female gamete generation GO:0007292 2 0.148
cell development GO:0048468 328 0.147
cytoplasmic transport GO:0016482 379 0.122
cellular macromolecule catabolic process GO:0044265 380 0.104
regulation of mitotic cell cycle GO:0007346 189 0.084
neurogenesis GO:0022008 169 0.074
neuroblast proliferation GO:0007405 4 0.070
regulation of neuroblast proliferation GO:1902692 3 0.065
oogenesis GO:0048477 2 0.058
stem cell differentiation GO:0048863 93 0.055
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.054
vesicle mediated transport GO:0016192 371 0.052
embryo development GO:0009790 123 0.051
negative regulation of cell differentiation GO:0045596 171 0.048
regulation of cellular component biogenesis GO:0044087 281 0.046
regulation of neural precursor cell proliferation GO:2000177 4 0.046
golgi vesicle transport GO:0048193 80 0.046
protein import into peroxisome matrix GO:0016558 11 0.046
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.045
negative regulation of developmental process GO:0051093 247 0.045
cellular amine metabolic process GO:0044106 41 0.045
positive regulation of cellular catabolic process GO:0031331 284 0.045
small gtpase mediated signal transduction GO:0007264 78 0.044
maintenance of location GO:0051235 112 0.042
microtubule based movement GO:0007018 32 0.041
protein targeting GO:0006605 187 0.041
locomotory behavior GO:0007626 1 0.039
nervous system development GO:0007399 293 0.039
cellular amino acid metabolic process GO:0006520 116 0.039
photoreceptor cell differentiation GO:0046530 2 0.038
growth GO:0040007 202 0.038
regulation of cell cycle process GO:0010564 266 0.038
amine metabolic process GO:0009308 44 0.038
lipid metabolic process GO:0006629 381 0.037
regulation of cellular amine metabolic process GO:0033238 11 0.037
negative regulation of multicellular organismal process GO:0051241 317 0.037
positive regulation of catabolic process GO:0009896 310 0.037
modification dependent protein catabolic process GO:0019941 209 0.037
cellular protein catabolic process GO:0044257 261 0.036
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.035
meiotic chromosome segregation GO:0045132 4 0.035
organonitrogen compound biosynthetic process GO:1901566 200 0.035
determination of adult lifespan GO:0008340 2 0.034
positive regulation of synaptic transmission GO:0050806 4 0.034
positive regulation of cell cycle process GO:0090068 106 0.032
multicellular organismal aging GO:0010259 3 0.032
circulatory system development GO:0072359 262 0.032
protein targeting to peroxisome GO:0006625 15 0.031
regulation of cellular amino acid metabolic process GO:0006521 6 0.031
mitotic cell cycle process GO:1903047 286 0.031
adult locomotory behavior GO:0008344 1 0.031
regulation of cell cycle GO:0051726 393 0.031
lipid biosynthetic process GO:0008610 177 0.031
membrane organization GO:0061024 292 0.030
anterior posterior axis specification GO:0009948 2 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.030
regulation of synaptic transmission dopaminergic GO:0032225 4 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.029
negative regulation of cellular component organization GO:0051129 235 0.029
single organism cellular localization GO:1902580 332 0.029
endomembrane system organization GO:0010256 196 0.028
nuclear migration GO:0007097 1 0.028
behavior GO:0007610 112 0.028
single organism reproductive process GO:0044702 98 0.027
segmentation GO:0035282 4 0.027
negative regulation of cellular amine metabolic process GO:0033239 3 0.027
regulation of cell development GO:0060284 161 0.026
nucleoside phosphate catabolic process GO:1901292 412 0.026
secretion by cell GO:0032940 226 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
regulation of immune response GO:0050776 201 0.025
secretion GO:0046903 254 0.025
organelle localization GO:0051640 84 0.025
gtp catabolic process GO:0006184 237 0.025
maintenance of protein location in cell GO:0032507 56 0.025
peroxisomal transport GO:0043574 15 0.025
positive regulation of protein catabolic process GO:0045732 75 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
protein oligomerization GO:0051259 173 0.024
desensitization of g protein coupled receptor protein signaling pathway by arrestin GO:0002032 2 0.024
regulation of cellular ketone metabolic process GO:0010565 50 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
protein localization to organelle GO:0033365 280 0.024
blastocyst development GO:0001824 3 0.023
regulation of innate immune response GO:0045088 97 0.023
response to lipid GO:0033993 206 0.023
reproductive process GO:0022414 106 0.023
protein acylation GO:0043543 138 0.022
regulation of protein catabolic process GO:0042176 155 0.022
negative regulation of immune system process GO:0002683 136 0.022
nucleotide catabolic process GO:0009166 408 0.022
blastoderm segmentation GO:0007350 2 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
regulation of response to external stimulus GO:0032101 222 0.022
positive regulation of developmental process GO:0051094 314 0.022
maintenance of protein location GO:0045185 57 0.022
cardiac muscle cell contraction GO:0086003 4 0.022
neuron differentiation GO:0030182 138 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
oxidation reduction process GO:0055114 396 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.021
vesicle organization GO:0016050 62 0.021
maintenance of location in cell GO:0051651 62 0.021
rho protein signal transduction GO:0007266 26 0.021
microtubule based process GO:0007017 210 0.021
ras protein signal transduction GO:0007265 73 0.021
cell cell signaling GO:0007267 155 0.021
gtp metabolic process GO:0046039 239 0.020
cell projection organization GO:0030030 252 0.020
negative regulation of cell development GO:0010721 48 0.020
proteasomal protein catabolic process GO:0010498 176 0.020
negative regulation of neural precursor cell proliferation GO:2000178 1 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
protein acetylation GO:0006473 116 0.020
regulation of establishment of protein localization GO:0070201 242 0.019
organelle assembly GO:0070925 176 0.019
positive regulation of meiotic cell cycle GO:0051446 2 0.019
neuron development GO:0048666 113 0.019
negative regulation of cell proliferation GO:0008285 228 0.019
rna interference GO:0016246 4 0.019
embryo development ending in birth or egg hatching GO:0009792 34 0.019
negative regulation of protein metabolic process GO:0051248 391 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
regeneration GO:0031099 4 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
cell morphogenesis GO:0000902 296 0.019
cerebral cortex cell migration GO:0021795 3 0.018
sensory perception of pain GO:0019233 4 0.018
regulation of cell differentiation GO:0045595 393 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
cell cycle phase transition GO:0044770 173 0.018
regulation of defense response GO:0031347 154 0.018
regulation of reactive oxygen species metabolic process GO:2000377 41 0.018
establishment of organelle localization GO:0051656 59 0.018
negative regulation of transport GO:0051051 176 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
negative regulation of immune response GO:0050777 40 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.017
cellular ketone metabolic process GO:0042180 80 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
sex differentiation GO:0007548 45 0.017
cell part morphogenesis GO:0032990 137 0.017
regulation of protein transport GO:0051223 213 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
regulation of intracellular transport GO:0032386 195 0.016
regulation of proteasomal protein catabolic process GO:0061136 87 0.016
intracellular protein transport GO:0006886 270 0.016
positive regulation of gtp catabolic process GO:0033126 166 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.016
cellular response to nutrient levels GO:0031669 69 0.016
regulation of gtpase activity GO:0043087 180 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
positive regulation of gtpase activity GO:0043547 166 0.016
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
negative regulation of protein kinase activity GO:0006469 98 0.016
small molecule biosynthetic process GO:0044283 157 0.016
response to bacterium GO:0009617 144 0.016
purine containing compound catabolic process GO:0072523 411 0.016
negative regulation of stem cell proliferation GO:2000647 3 0.016
generation of neurons GO:0048699 152 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
positive regulation of transport GO:0051050 336 0.015
memory GO:0007613 3 0.015
peptidyl lysine modification GO:0018205 144 0.015
protein catabolic process GO:0030163 325 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
response to external biotic stimulus GO:0043207 261 0.015
regulation of chromosome segregation GO:0051983 44 0.015
endosomal transport GO:0016197 129 0.015
reproductive system development GO:0061458 56 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
positive regulation of proteolysis GO:0045862 142 0.015
neuromuscular junction development GO:0007528 3 0.015
metal ion transport GO:0030001 272 0.015
protein import into nucleus GO:0006606 104 0.015
positive regulation of cell cycle GO:0045787 140 0.015
regulation of mitosis GO:0007088 63 0.014
tissue migration GO:0090130 119 0.014
protein secretion GO:0009306 98 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
system process GO:0003008 349 0.014
establishment of nucleus localization GO:0040023 1 0.014
positive regulation of cellular protein catabolic process GO:1903364 37 0.014
regulation of protein localization GO:0032880 296 0.014
mitotic sister chromatid separation GO:0051306 18 0.014
ameboidal type cell migration GO:0001667 135 0.014
organelle fission GO:0048285 149 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
tripartite regional subdivision GO:0007351 2 0.014
gonad development GO:0008406 34 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
regulation of locomotion GO:0040012 329 0.014
mitotic sister chromatid segregation GO:0000070 53 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
cellular protein complex assembly GO:0043623 188 0.014
cardiovascular system development GO:0072358 262 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
cell division GO:0051301 168 0.014
mitotic nuclear division GO:0007067 119 0.014
regulation of mitochondrion organization GO:0010821 54 0.014
regulation of transferase activity GO:0051338 355 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
regulation of chromosome organization GO:0033044 103 0.013
protein targeting to nucleus GO:0044744 104 0.013
negative regulation of protein modification process GO:0031400 200 0.013
cellular component morphogenesis GO:0032989 314 0.013
immune response GO:0006955 307 0.013
regulation of cell division GO:0051302 116 0.013
regulation of protein binding GO:0043393 66 0.013
regulation of protein complex assembly GO:0043254 147 0.013
chromosome segregation GO:0007059 114 0.013
hindbrain development GO:0030902 3 0.013
actin filament based movement GO:0030048 17 0.013
regulation of cytokine production GO:0001817 232 0.013
carbohydrate metabolic process GO:0005975 207 0.013
peptidyl tyrosine modification GO:0018212 170 0.013
purine nucleoside triphosphate catabolic process GO:0009146 392 0.013
angiogenesis GO:0001525 147 0.013
regulation of binding GO:0051098 111 0.013
protein import GO:0017038 130 0.013
microtubule anchoring GO:0034453 24 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
establishment of protein localization to membrane GO:0090150 121 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
head development GO:0060322 108 0.012
transmembrane transport GO:0055085 399 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
defense response GO:0006952 315 0.012
positive regulation of immune response GO:0050778 159 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.012
divalent inorganic cation transport GO:0072511 158 0.012
membrane lipid metabolic process GO:0006643 53 0.012
reproduction GO:0000003 63 0.012
sister chromatid segregation GO:0000819 54 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
actin filament based process GO:0030029 224 0.012
peroxisome organization GO:0007031 28 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
striated muscle myosin thick filament assembly GO:0071688 2 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
innate immune response GO:0045087 178 0.012
cell projection morphogenesis GO:0048858 129 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
regulation of cytoplasmic transport GO:1903649 149 0.011
vasculature development GO:0001944 181 0.011
single organism membrane organization GO:0044802 268 0.011
developmental process involved in reproduction GO:0003006 66 0.011
mitochondrion organization GO:0007005 156 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
organ formation GO:0048645 3 0.011
oocyte development GO:0048599 1 0.011
negative regulation of cell cycle GO:0045786 193 0.011
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
nuclear transport GO:0051169 179 0.011
endocytosis GO:0006897 159 0.011
cellular component disassembly GO:0022411 92 0.011
mitotic cell cycle GO:0000278 326 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
endoplasmic reticulum organization GO:0007029 20 0.011
dna templated transcription initiation GO:0006352 35 0.011
negative regulation of defense response GO:0031348 47 0.011
protein localization to membrane GO:0072657 160 0.011
response to abiotic stimulus GO:0009628 336 0.011
heart development GO:0007507 95 0.011
receptor mediated endocytosis GO:0006898 84 0.011
development of primary sexual characteristics GO:0045137 35 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
g protein coupled receptor signaling pathway GO:0007186 207 0.011
blood vessel development GO:0001568 172 0.011
internal peptidyl lysine acetylation GO:0018393 97 0.010
nucleus localization GO:0051647 1 0.010
response to other organism GO:0051707 261 0.010
neuron projection development GO:0031175 106 0.010
histone h3 acetylation GO:0043966 45 0.010
neural crest cell migration GO:0001755 2 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010
eye photoreceptor cell differentiation GO:0001754 2 0.010
negative regulation of cell cycle phase transition GO:1901988 89 0.010
nuclear division GO:0000280 128 0.010
response to oxygen containing compound GO:1901700 369 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
negative regulation of cellular protein metabolic process GO:0032269 353 0.010
compound eye development GO:0048749 1 0.010
nucleoside triphosphate catabolic process GO:0009143 394 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
regulation of cellular response to stress GO:0080135 244 0.010
epithelium migration GO:0090132 119 0.010

MED8 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.021
brain disease DOID:936 73 0.021
nervous system disease DOID:863 431 0.021
disease of metabolism DOID:0014667 295 0.018
sensory system disease DOID:0050155 203 0.017
eye and adnexa disease DOID:1492 150 0.017
eye disease DOID:5614 149 0.017
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
retinal disease DOID:5679 118 0.014
immune system disease DOID:2914 155 0.013