Homo sapiens

285 known processes

AKR1C3

aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)

(Aliases: hluPGFS,DDX,KIAA0119,DD3,HA1753,HAKRB,HAKRe,HSD17B5,PGFS)

AKR1C3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
androgen biosynthetic process GO:0006702 3 1.000
retinoic acid biosynthetic process GO:0002138 2 1.000
testosterone biosynthetic process GO:0061370 2 1.000
regulation of testosterone biosynthetic process GO:2000224 2 1.000
diterpenoid biosynthetic process GO:0016102 2 1.000
ketone catabolic process GO:0042182 3 1.000
primary alcohol catabolic process GO:0034310 3 1.000
sterol catabolic process GO:0016127 3 1.000
Human
retinoid metabolic process GO:0001523 18 0.999
cellular response to prostaglandin stimulus GO:0071379 4 0.999
primary alcohol metabolic process GO:0034308 17 0.999
glycoside metabolic process GO:0016137 13 0.998
doxorubicin metabolic process GO:0044598 8 0.998
isoprenoid catabolic process GO:0008300 7 0.994
cholesterol catabolic process GO:0006707 3 0.993
Human
progesterone metabolic process GO:0042448 6 0.991
response to jasmonic acid GO:0009753 4 0.988
cellular response to jasmonic acid stimulus GO:0071395 4 0.987
hormone catabolic process GO:0042447 4 0.986
regulation of retinoic acid biosynthetic process GO:1900052 1 0.983
sesquiterpenoid metabolic process GO:0006714 3 0.979
farnesol catabolic process GO:0016488 2 0.966
regulation of isoprenoid metabolic process GO:0019747 1 0.963
retinal metabolic process GO:0042574 8 0.962
daunorubicin metabolic process GO:0044597 8 0.960
prostanoid metabolic process GO:0006692 17 0.947
regulation of ketone biosynthetic process GO:0010566 7 0.937
diterpenoid metabolic process GO:0016101 20 0.903
aminoglycoside antibiotic metabolic process GO:0030647 8 0.902
terpenoid metabolic process GO:0006721 27 0.895
farnesol metabolic process GO:0016487 2 0.893
bile acid metabolic process GO:0008206 14 0.878
Human
vitamin metabolic process GO:0006766 26 0.878
limbic system development GO:0021761 3 0.857
Rat
icosanoid metabolic process GO:0006690 35 0.853
sesquiterpenoid catabolic process GO:0016107 2 0.847
terpenoid biosynthetic process GO:0016114 2 0.832
terpenoid catabolic process GO:0016115 5 0.822
response to prostaglandin GO:0034694 8 0.810
negative regulation of isoprenoid metabolic process GO:0045827 1 0.789
bile acid biosynthetic process GO:0006699 10 0.777
Human
fatty acid derivative metabolic process GO:1901568 35 0.774
ketone biosynthetic process GO:0042181 17 0.762
cellular hormone metabolic process GO:0034754 41 0.744
retinoic acid metabolic process GO:0042573 7 0.741
quinone metabolic process GO:1901661 18 0.739
lipid catabolic process GO:0016042 84 0.720
oxidation reduction process GO:0055114 396 0.717
response to fatty acid GO:0070542 13 0.692
cellular lipid catabolic process GO:0044242 65 0.687
steroid catabolic process GO:0006706 10 0.676
Human
cellular aldehyde metabolic process GO:0006081 20 0.658
alcohol metabolic process GO:0006066 114 0.638
polyketide metabolic process GO:0030638 8 0.632
g protein coupled receptor signaling pathway GO:0007186 207 0.624
cellular response to calcium ion GO:0071277 19 0.616
hippocampus development GO:0021766 1 0.613
Rat
cofactor metabolic process GO:0051186 87 0.609
isoprenoid metabolic process GO:0006720 39 0.587
lipid biosynthetic process GO:0008610 177 0.586
organic acid biosynthetic process GO:0016053 97 0.584
parturition GO:0007567 1 0.579
negative regulation of retinoic acid biosynthetic process GO:1900053 1 0.572
unsaturated fatty acid metabolic process GO:0033559 37 0.570
steroid metabolic process GO:0008202 94 0.556
carboxylic acid biosynthetic process GO:0046394 97 0.538
small molecule biosynthetic process GO:0044283 157 0.537
negative regulation of lipid metabolic process GO:0045833 38 0.527
cellular response to corticosteroid stimulus GO:0071384 5 0.524
small molecule catabolic process GO:0044282 92 0.523
hormone metabolic process GO:0042445 61 0.521
organic hydroxy compound catabolic process GO:1901616 22 0.511
digestion GO:0007586 22 0.508
Human
fatty acid metabolic process GO:0006631 115 0.479
regulation of cellular ketone metabolic process GO:0010565 50 0.477
cellular lipid metabolic process GO:0044255 303 0.467
prostaglandin metabolic process GO:0006693 17 0.464
lipid metabolic process GO:0006629 381 0.450
steroid biosynthetic process GO:0006694 46 0.449
isoprenoid biosynthetic process GO:0008299 9 0.427
regulation of vitamin metabolic process GO:0030656 9 0.419
androgen metabolic process GO:0008209 9 0.417
organic hydroxy compound metabolic process GO:1901615 147 0.408
monocarboxylic acid biosynthetic process GO:0072330 67 0.408
cellular response to fatty acid GO:0071398 8 0.403
secondary metabolic process GO:0019748 17 0.399
multicellular organismal metabolic process GO:0044236 34 0.396
cellular response to oxidative stress GO:0034599 85 0.396
cellular ketone metabolic process GO:0042180 80 0.373
regulation of endothelial cell apoptotic process GO:2000351 24 0.360
regulation of hormone levels GO:0010817 125 0.358
response to calcium ion GO:0051592 46 0.350
keratinocyte differentiation GO:0030216 36 0.322
hormone biosynthetic process GO:0042446 22 0.317
protein homooligomerization GO:0051260 100 0.317
Human
cholesterol metabolic process GO:0008203 28 0.311
Human
regulation of reactive oxygen species metabolic process GO:2000377 41 0.308
positive regulation of cell proliferation GO:0008284 301 0.305
response to hormone GO:0009725 175 0.305
regulation of hormone metabolic process GO:0032350 14 0.303
response to oxidative stress GO:0006979 121 0.293
protein localization to organelle GO:0033365 280 0.276
positive regulation of apoptotic process GO:0043065 246 0.273
organic hydroxy compound biosynthetic process GO:1901617 71 0.272
reactive oxygen species metabolic process GO:0072593 75 0.267
sterol metabolic process GO:0016125 28 0.262
Human
negative regulation of vitamin metabolic process GO:0046137 6 0.245
regulation of lipid biosynthetic process GO:0046890 47 0.239
response to organic cyclic compound GO:0014070 204 0.239
cytoplasmic transport GO:0016482 379 0.236
cellular response to organic cyclic compound GO:0071407 127 0.236
cell type specific apoptotic process GO:0097285 125 0.234
negative regulation of hormone metabolic process GO:0032351 6 0.234
protein oligomerization GO:0051259 173 0.233
Human
positive regulation of programmed cell death GO:0043068 249 0.232
regulation of alcohol biosynthetic process GO:1902930 22 0.231
regulation of hormone biosynthetic process GO:0046885 10 0.228
response to estrogen GO:0043627 47 0.225
Rat
cellular response to reactive oxygen species GO:0034614 50 0.217
response to organophosphorus GO:0046683 41 0.213
Human
cellular response to oxygen containing compound GO:1901701 276 0.211
c21 steroid hormone metabolic process GO:0008207 17 0.211
cellular response to metal ion GO:0071248 43 0.211
response to steroid hormone GO:0048545 80 0.207
positive regulation of endothelial cell apoptotic process GO:2000353 8 0.206
protein targeting GO:0006605 187 0.205
cellular response to nutrient levels GO:0031669 69 0.204
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.202
single organism cellular localization GO:1902580 332 0.198
regulation of steroid metabolic process GO:0019218 32 0.197
cellular response to external stimulus GO:0071496 111 0.195
rna processing GO:0006396 255 0.193
epidermal cell differentiation GO:0009913 45 0.190
regulation of lipid metabolic process GO:0019216 96 0.190
response to lipid GO:0033993 206 0.185
epithelial cell differentiation GO:0030855 141 0.184
endothelial cell apoptotic process GO:0072577 26 0.183
cellular response to endogenous stimulus GO:0071495 336 0.183
cellular response to acid chemical GO:0071229 44 0.181
mrna processing GO:0006397 133 0.175
protein targeting to nucleus GO:0044744 104 0.173
positive regulation of cell death GO:0010942 263 0.171
single organism nuclear import GO:1902593 104 0.170
nuclear transport GO:0051169 179 0.169
response to inorganic substance GO:0010035 127 0.169
intracellular receptor signaling pathway GO:0030522 104 0.167
response to metal ion GO:0010038 84 0.167
male gonad development GO:0008584 23 0.164
multicellular organismal macromolecule metabolic process GO:0044259 29 0.163
development of primary male sexual characteristics GO:0046546 23 0.154
regulation of steroid biosynthetic process GO:0050810 23 0.153
cellular response to starvation GO:0009267 58 0.153
alcohol biosynthetic process GO:0046165 52 0.152
negative regulation of lipid biosynthetic process GO:0051055 22 0.148
response to oxygen containing compound GO:1901700 369 0.147
cellular response to inorganic substance GO:0071241 45 0.146
cellular response to hormone stimulus GO:0032870 125 0.145
establishment of protein localization to organelle GO:0072594 172 0.144
protein import into nucleus GO:0006606 104 0.143
response to drug GO:0042493 81 0.141
Rat
cellular response to lipid GO:0071396 127 0.138
epidermis development GO:0008544 59 0.138
cellular response to steroid hormone stimulus GO:0071383 37 0.137
skin development GO:0043588 76 0.135
protein localization to nucleus GO:0034504 136 0.134
response to nutrient GO:0007584 20 0.131
epithelium development GO:0060429 227 0.131
retinoic acid receptor signaling pathway GO:0048384 13 0.127
regulation of retinoic acid receptor signaling pathway GO:0048385 9 0.124
nucleocytoplasmic transport GO:0006913 176 0.122
response to reactive oxygen species GO:0000302 61 0.119
male sex differentiation GO:0046661 25 0.119
response to extracellular stimulus GO:0009991 85 0.115
alcohol catabolic process GO:0046164 20 0.110
response to acid chemical GO:0001101 66 0.109
nuclear import GO:0051170 106 0.109
mrna metabolic process GO:0016071 175 0.109
protein kinase b signaling GO:0043491 69 0.098
telencephalon development GO:0021537 17 0.094
Rat
protein import GO:0017038 130 0.092
cellular amino acid metabolic process GO:0006520 116 0.092
negative regulation of mrna metabolic process GO:1903312 15 0.091
response to corticosteroid GO:0031960 15 0.089
response to cadmium ion GO:0046686 10 0.088
response to starvation GO:0042594 59 0.082
nervous system development GO:0007399 293 0.082
Rat
head development GO:0060322 108 0.082
Rat
cellular response to extracellular stimulus GO:0031668 72 0.075
brain development GO:0007420 97 0.074
Rat
response to nutrient levels GO:0031667 81 0.072
regulation of protein kinase b signaling GO:0051896 61 0.071
rna splicing via transesterification reactions GO:0000375 90 0.064
central nervous system development GO:0007417 123 0.053
Rat
locomotory behavior GO:0007626 1 0.051
glycosyl compound catabolic process GO:1901658 413 0.048
protein import into nucleus translocation GO:0000060 22 0.047
purine ribonucleoside metabolic process GO:0046128 437 0.044
negative regulation of rna splicing GO:0033119 15 0.044
cellular macromolecule catabolic process GO:0044265 380 0.043
system process GO:0003008 349 0.043
amine metabolic process GO:0009308 44 0.041
determination of adult lifespan GO:0008340 2 0.040
nucleoside triphosphate metabolic process GO:0009141 422 0.040
regulation of mrna processing GO:0050684 48 0.040
post embryonic development GO:0009791 2 0.040
purine ribonucleoside catabolic process GO:0046130 398 0.039
purine nucleotide catabolic process GO:0006195 405 0.038
forebrain development GO:0030900 26 0.037
Rat
blastoderm segmentation GO:0007350 2 0.037
monocarboxylic acid metabolic process GO:0032787 185 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
neuromuscular junction development GO:0007528 3 0.036
regulation of cellular component biogenesis GO:0044087 281 0.036
reproductive system development GO:0061458 56 0.035
nucleotide catabolic process GO:0009166 408 0.035
organonitrogen compound biosynthetic process GO:1901566 200 0.035
multicellular organismal aging GO:0010259 3 0.034
purine containing compound catabolic process GO:0072523 411 0.034
ribonucleoside catabolic process GO:0042454 406 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.033
lung alveolus development GO:0048286 4 0.032
negative regulation of mrna splicing via spliceosome GO:0048025 11 0.031
guanosine containing compound metabolic process GO:1901068 244 0.030
actin filament based process GO:0030029 224 0.030
sulfur compound metabolic process GO:0006790 101 0.030
negative regulation of phosphate metabolic process GO:0045936 267 0.030
nucleoside catabolic process GO:0009164 408 0.029
segmentation GO:0035282 4 0.029
female gamete generation GO:0007292 2 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
negative regulation of cell death GO:0060548 345 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
cellular amine metabolic process GO:0044106 41 0.028
startle response GO:0001964 3 0.028
positive regulation of transport GO:0051050 336 0.028
memory GO:0007613 3 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
adult locomotory behavior GO:0008344 1 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
regulation of synaptic plasticity GO:0048167 3 0.027
oogenesis GO:0048477 2 0.027
gtp metabolic process GO:0046039 239 0.027
nucleoside triphosphate catabolic process GO:0009143 394 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
maintenance of location GO:0051235 112 0.026
organophosphate catabolic process GO:0046434 430 0.026
negative regulation of apoptotic process GO:0043066 316 0.026
secretion by cell GO:0032940 226 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
positive regulation of cellular component organization GO:0051130 376 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
rna splicing GO:0008380 131 0.026
membrane organization GO:0061024 292 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
peripheral nervous system development GO:0007422 2 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
protein ubiquitination GO:0016567 314 0.024
cytokine production GO:0001816 247 0.024
reproductive process GO:0022414 106 0.023
circadian behavior GO:0048512 2 0.023
signal transduction by phosphorylation GO:0023014 297 0.023
cellular response to cadmium ion GO:0071276 8 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
transmembrane transport GO:0055085 399 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
anterior posterior axis specification GO:0009948 2 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
tripartite regional subdivision GO:0007351 2 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
negative regulation of programmed cell death GO:0043069 321 0.022
regeneration GO:0031099 4 0.022
oocyte development GO:0048599 1 0.021
response to abiotic stimulus GO:0009628 336 0.021
single organism reproductive process GO:0044702 98 0.021
meiotic chromosome segregation GO:0045132 4 0.021
ion homeostasis GO:0050801 230 0.021
reproductive structure development GO:0048608 55 0.021
intracellular mrna localization GO:0008298 1 0.021
regulation of cell maturation GO:1903429 3 0.020
mapk cascade GO:0000165 288 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
cation homeostasis GO:0055080 189 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
regulation of cellular response to stress GO:0080135 244 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
reactive oxygen species biosynthetic process GO:1903409 4 0.020
regulation of peptidase activity GO:0052547 180 0.020
single organism membrane organization GO:0044802 268 0.020
protein processing GO:0016485 226 0.019
rhythmic behavior GO:0007622 2 0.019
protein maturation GO:0051604 233 0.019
apoptotic signaling pathway GO:0097190 268 0.019
mitotic cell cycle GO:0000278 326 0.019
pituitary gland development GO:0021983 2 0.019
spermatid differentiation GO:0048515 4 0.019
cell development GO:0048468 328 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
coenzyme metabolic process GO:0006732 65 0.019
ras protein signal transduction GO:0007265 73 0.019
neurological system process GO:0050877 163 0.019
negative regulation of protein modification process GO:0031400 200 0.019
cellular amide metabolic process GO:0043603 69 0.019
regulation of protein transport GO:0051223 213 0.019
biological adhesion GO:0022610 331 0.019
regulation of cell differentiation GO:0045595 393 0.019
small gtpase mediated signal transduction GO:0007264 78 0.019
oocyte differentiation GO:0009994 2 0.019
tissue regeneration GO:0042246 3 0.019
i kappab kinase nf kappab signaling GO:0007249 166 0.019
development of primary sexual characteristics GO:0045137 35 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
regulation of cell cycle process GO:0010564 266 0.018
modification dependent macromolecule catabolic process GO:0043632 212 0.018
intracellular protein transport GO:0006886 270 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
cardiac muscle cell contraction GO:0086003 4 0.018
response to growth factor GO:0070848 205 0.018
gtp catabolic process GO:0006184 237 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.018
visual learning GO:0008542 1 0.018
morphogenesis of embryonic epithelium GO:0016331 4 0.018
cellular protein catabolic process GO:0044257 261 0.018
spermatid development GO:0007286 4 0.018
regulation of secretion by cell GO:1903530 177 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
regulation of protein localization GO:0032880 296 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
cell morphogenesis GO:0000902 296 0.017
positive regulation of synaptic transmission GO:0050806 4 0.017
regulation of neuronal synaptic plasticity GO:0048168 1 0.017
regulation of proteolysis GO:0030162 293 0.017
cellular protein complex assembly GO:0043623 188 0.017
nucleoside phosphate biosynthetic process GO:1901293 109 0.017
positive regulation of gliogenesis GO:0014015 4 0.017
regulation of cellular component movement GO:0051270 334 0.017
sex differentiation GO:0007548 45 0.017
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 3 0.017
regulation of protein maturation GO:1903317 150 0.017
regulation of protein kinase activity GO:0045859 289 0.017
protein catabolic process GO:0030163 325 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
positive regulation of glial cell proliferation GO:0060252 2 0.016
cell projection organization GO:0030030 252 0.016
extrinsic apoptotic signaling pathway GO:0097191 119 0.016
regulation of immune response GO:0050776 201 0.016
protein localization to membrane GO:0072657 160 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
regulation of cytokine production GO:0001817 232 0.016
regulation of cell cycle GO:0051726 393 0.016
cellular modified amino acid metabolic process GO:0006575 64 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
regulation of protein processing GO:0070613 150 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
mating GO:0007618 1 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
reactive nitrogen species metabolic process GO:2001057 3 0.016
negative regulation of protein maturation GO:1903318 142 0.016
defense response GO:0006952 315 0.016
rho protein signal transduction GO:0007266 26 0.016
positive regulation of proteolysis GO:0045862 142 0.016
positive regulation of immune system process GO:0002684 283 0.016
regulation of secretion GO:0051046 194 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
negative regulation of protein processing GO:0010955 142 0.016
organophosphate biosynthetic process GO:0090407 163 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
nucleotide biosynthetic process GO:0009165 109 0.016
engulfment of apoptotic cell GO:0043652 2 0.016
negative regulation of transport GO:0051051 176 0.015
positive regulation of hydrolase activity GO:0051345 331 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.015
glial cell migration GO:0008347 4 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
negative regulation of t cell apoptotic process GO:0070233 4 0.015
immune effector process GO:0002252 159 0.015
cellular component morphogenesis GO:0032989 314 0.015
9 cis retinoic acid metabolic process GO:0042905 1 0.015
carbohydrate metabolic process GO:0005975 207 0.015
innate immune response GO:0045087 178 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
cofactor biosynthetic process GO:0051188 31 0.015
dicarboxylic acid metabolic process GO:0043648 29 0.015
immune response GO:0006955 307 0.015
regulation of rna splicing GO:0043484 62 0.015
inner ear morphogenesis GO:0042472 4 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
response to biotic stimulus GO:0009607 276 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
trabecula morphogenesis GO:0061383 2 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
motor neuron axon guidance GO:0008045 2 0.014
sensory perception of smell GO:0007608 2 0.014
cellular homeostasis GO:0019725 196 0.014
cell fate determination GO:0001709 3 0.014
epidermis morphogenesis GO:0048730 3 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
positive regulation of secretion by cell GO:1903532 108 0.014
nucleus localization GO:0051647 1 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.014
purine nucleotide biosynthetic process GO:0006164 84 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
cell growth GO:0016049 160 0.014
positive regulation of transferase activity GO:0051347 227 0.014
associative learning GO:0008306 1 0.014
regulation of protein complex assembly GO:0043254 147 0.014
apoptotic mitochondrial changes GO:0008637 57 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
ion transmembrane transport GO:0034220 338 0.014
visual behavior GO:0007632 2 0.014
compound eye development GO:0048749 1 0.014
dephosphorylation GO:0016311 209 0.014
morphogenesis of a polarized epithelium GO:0001738 3 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
chromosome segregation GO:0007059 114 0.014
actin cytoskeleton organization GO:0030036 207 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
gonad development GO:0008406 34 0.014
nitrogen compound transport GO:0071705 191 0.014
melanin metabolic process GO:0006582 1 0.014
positive regulation of vasoconstriction GO:0045907 3 0.014
response to nitrogen compound GO:1901698 184 0.014
cation transmembrane transport GO:0098655 238 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
regulation of kinase activity GO:0043549 314 0.013
positive regulation of secretion GO:0051047 116 0.013
regulation of growth GO:0040008 165 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
mitotic cell cycle process GO:1903047 286 0.013
negative regulation of cell cycle GO:0045786 193 0.013
regulation of glial cell proliferation GO:0060251 4 0.013
atp metabolic process GO:0046034 176 0.013
multi organism reproductive process GO:0044703 54 0.013
positive regulation of kinase activity GO:0033674 204 0.013
purine ribonucleotide biosynthetic process GO:0009152 79 0.013
striated muscle cell apoptotic process GO:0010658 3 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
cell cycle phase transition GO:0044770 173 0.013
organelle assembly GO:0070925 176 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
dna repair GO:0006281 198 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
skeletal muscle tissue growth GO:0048630 2 0.013
sequestering of metal ion GO:0051238 24 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.012
positive regulation of catabolic process GO:0009896 310 0.012
cellular ion homeostasis GO:0006873 168 0.012
actin mediated cell contraction GO:0070252 12 0.012
microtubule based process GO:0007017 210 0.012
sulfur compound biosynthetic process GO:0044272 38 0.012
regulation of cell migration GO:0030334 289 0.012

AKR1C3 disease predictions

Disease DO term ID Size Probability Func Analog Org
chromosomal disease DOID:0080014 16 0.192
Human
gonadal dysgenesis DOID:14447 8 0.072
Human
46 xy gonadal dysgenesis DOID:14448 8 0.072
Human
disease of metabolism DOID:0014667 295 0.034
Human
musculoskeletal system disease DOID:17 223 0.032
sensory system disease DOID:0050155 203 0.029
eye and adnexa disease DOID:1492 150 0.029
nervous system disease DOID:863 431 0.029
eye disease DOID:5614 149 0.029
cardiovascular system disease DOID:1287 106 0.026
immune system disease DOID:2914 155 0.025
central nervous system disease DOID:331 186 0.022
myopathy DOID:423 104 0.020
muscular disease DOID:0080000 114 0.020
muscle tissue disease DOID:66 113 0.020
disease of cellular proliferation DOID:14566 174 0.020
cancer DOID:162 167 0.017
organ system cancer DOID:0050686 164 0.017
retinal disease DOID:5679 118 0.016
connective tissue disease DOID:65 109 0.015
neurodegenerative disease DOID:1289 102 0.015
heart disease DOID:114 68 0.014
retinal degeneration DOID:8466 89 0.014
bone disease DOID:0080001 88 0.013
hematopoietic system disease DOID:74 100 0.012