Homo sapiens

0 known processes

GCA

grancalcin, EF-hand calcium binding protein

(Aliases: GCL)

GCA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate derivative biosynthetic process GO:1901137 207 0.055
negative regulation of protein metabolic process GO:0051248 391 0.055
purine ribonucleoside metabolic process GO:0046128 437 0.054
locomotory behavior GO:0007626 1 0.054
positive regulation of transport GO:0051050 336 0.049
multicellular organismal aging GO:0010259 3 0.045
negative regulation of cellular protein metabolic process GO:0032269 353 0.045
protein localization to organelle GO:0033365 280 0.044
regulation of cell cycle GO:0051726 393 0.042
immune response GO:0006955 307 0.041
actin filament based process GO:0030029 224 0.041
Human
female gamete generation GO:0007292 2 0.041
cytoplasmic transport GO:0016482 379 0.037
nucleoside triphosphate catabolic process GO:0009143 394 0.037
regulation of purine nucleotide metabolic process GO:1900542 264 0.036
negative regulation of catalytic activity GO:0043086 335 0.036
organophosphate biosynthetic process GO:0090407 163 0.036
cell morphogenesis GO:0000902 296 0.035
purine nucleoside triphosphate metabolic process GO:0009144 412 0.034
nucleotide catabolic process GO:0009166 408 0.033
oogenesis GO:0048477 2 0.033
ribonucleoside catabolic process GO:0042454 406 0.033
positive regulation of hydrolase activity GO:0051345 331 0.033
organophosphate catabolic process GO:0046434 430 0.033
lipid metabolic process GO:0006629 381 0.033
regulation of establishment of protein localization GO:0070201 242 0.033
glycosyl compound catabolic process GO:1901658 413 0.033
ribonucleoside triphosphate catabolic process GO:0009203 391 0.032
response to external biotic stimulus GO:0043207 261 0.032
purine nucleoside triphosphate catabolic process GO:0009146 392 0.032
regulation of response to external stimulus GO:0032101 222 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.031
vesicle mediated transport GO:0016192 371 0.031
positive regulation of cellular component organization GO:0051130 376 0.031
positive regulation of catabolic process GO:0009896 310 0.031
ribonucleotide catabolic process GO:0009261 405 0.031
post embryonic development GO:0009791 2 0.031
cellular lipid metabolic process GO:0044255 303 0.030
protein modification by small protein conjugation GO:0032446 342 0.030
purine ribonucleoside catabolic process GO:0046130 398 0.030
determination of adult lifespan GO:0008340 2 0.030
secretion GO:0046903 254 0.029
defense response GO:0006952 315 0.029
single organism cellular localization GO:1902580 332 0.028
small molecule biosynthetic process GO:0044283 157 0.028
regulation of transferase activity GO:0051338 355 0.028
regulation of proteolysis GO:0030162 293 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.028
purine ribonucleotide catabolic process GO:0009154 404 0.028
nitrogen compound transport GO:0071705 191 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
negative regulation of phosphorylation GO:0042326 174 0.027
negative regulation of cell proliferation GO:0008285 228 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
cellular macromolecule catabolic process GO:0044265 380 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.026
mitotic cell cycle process GO:1903047 286 0.026
response to oxygen containing compound GO:1901700 369 0.026
regulation of protein transport GO:0051223 213 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.026
regulation of nucleotide metabolic process GO:0006140 269 0.026
single organism membrane organization GO:0044802 268 0.026
neuromuscular junction development GO:0007528 3 0.025
amine metabolic process GO:0009308 44 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.025
response to other organism GO:0051707 261 0.025
regulation of cellular response to stress GO:0080135 244 0.025
regulation of kinase activity GO:0043549 314 0.025
segmentation GO:0035282 4 0.025
guanosine containing compound catabolic process GO:1901069 239 0.025
cellular response to dna damage stimulus GO:0006974 379 0.024
cellular component morphogenesis GO:0032989 314 0.024
protein catabolic process GO:0030163 325 0.024
secretion by cell GO:0032940 226 0.024
cellular amine metabolic process GO:0044106 41 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
mitotic cell cycle GO:0000278 326 0.024
purine containing compound catabolic process GO:0072523 411 0.023
regulation of cellular ketone metabolic process GO:0010565 50 0.023
cellular amino acid metabolic process GO:0006520 116 0.023
cation transmembrane transport GO:0098655 238 0.023
Human
ion transmembrane transport GO:0034220 338 0.023
Human
purine nucleotide catabolic process GO:0006195 405 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
cell projection organization GO:0030030 252 0.023
memory GO:0007613 3 0.023
regeneration GO:0031099 4 0.023
cofactor metabolic process GO:0051186 87 0.022
cellular homeostasis GO:0019725 196 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
system process GO:0003008 349 0.022
Human
response to abiotic stimulus GO:0009628 336 0.022
immune effector process GO:0002252 159 0.022
adult locomotory behavior GO:0008344 1 0.022
cation transport GO:0006812 331 0.021
Human
nucleoside catabolic process GO:0009164 408 0.021
negative regulation of protein modification process GO:0031400 200 0.021
positive regulation of nucleotide metabolic process GO:0045981 230 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
ras protein signal transduction GO:0007265 73 0.021
response to virus GO:0009615 126 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.021
endomembrane system organization GO:0010256 196 0.020
circadian behavior GO:0048512 2 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
interspecies interaction between organisms GO:0044419 156 0.020
membrane organization GO:0061024 292 0.020
endosomal transport GO:0016197 129 0.020
regulation of protein localization GO:0032880 296 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
signal transduction by phosphorylation GO:0023014 297 0.019
chemical homeostasis GO:0048878 306 0.019
positive regulation of nucleotide catabolic process GO:0030813 185 0.019
organelle assembly GO:0070925 176 0.019
guanosine containing compound metabolic process GO:1901068 244 0.019
innate immune response GO:0045087 178 0.019
regulation of defense response GO:0031347 154 0.019
negative regulation of protein phosphorylation GO:0001933 140 0.019
regulation of cell differentiation GO:0045595 393 0.019
small gtpase mediated signal transduction GO:0007264 78 0.019
nucleoside monophosphate metabolic process GO:0009123 191 0.019
negative regulation of apoptotic process GO:0043066 316 0.018
organic hydroxy compound metabolic process GO:1901615 147 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
blastoderm segmentation GO:0007350 2 0.018
cardiac muscle cell contraction GO:0086003 4 0.018
Human
defense response to virus GO:0051607 71 0.018
vesicle organization GO:0016050 62 0.018
cellular response to oxygen containing compound GO:1901701 276 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
inorganic ion transmembrane transport GO:0098660 231 0.018
Human
apoptotic signaling pathway GO:0097190 268 0.018
oxidative stress induced premature senescence GO:0090403 3 0.018
nuclear transport GO:0051169 179 0.018
regulation of mapk cascade GO:0043408 262 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
regulation of cell cycle process GO:0010564 266 0.018
circulatory system development GO:0072359 262 0.018
generation of neurons GO:0048699 152 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
mapk cascade GO:0000165 288 0.018
positive regulation of phosphorylation GO:0042327 394 0.017
metal ion transport GO:0030001 272 0.017
Human
biological adhesion GO:0022610 331 0.017
protein oligomerization GO:0051259 173 0.017
autophagy GO:0006914 88 0.017
cell division GO:0051301 168 0.017
regulation of secretion GO:0051046 194 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
oocyte differentiation GO:0009994 2 0.017
negative regulation of cell cycle GO:0045786 193 0.017
regulation of intracellular protein transport GO:0033157 123 0.017
nervous system development GO:0007399 293 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
dephosphorylation GO:0016311 209 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
negative regulation of cell death GO:0060548 345 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
regulation of secretion by cell GO:1903530 177 0.016
blood coagulation GO:0007596 76 0.016
gtp catabolic process GO:0006184 237 0.016
lipid biosynthetic process GO:0008610 177 0.016
cell development GO:0048468 328 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
actin cytoskeleton organization GO:0030036 207 0.016
negative regulation of transport GO:0051051 176 0.016
Human
cellular ketone metabolic process GO:0042180 80 0.016
response to cytokine GO:0034097 232 0.016
cell part morphogenesis GO:0032990 137 0.016
spermatid differentiation GO:0048515 4 0.016
protein processing GO:0016485 226 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
regulation of protein complex assembly GO:0043254 147 0.016
negative regulation of transferase activity GO:0051348 124 0.016
cilium morphogenesis GO:0060271 75 0.016
positive regulation of gtpase activity GO:0043547 166 0.016
protein targeting GO:0006605 187 0.016
hindbrain development GO:0030902 3 0.016
spermatid development GO:0007286 4 0.016
epithelium development GO:0060429 227 0.016
response to biotic stimulus GO:0009607 276 0.015
maintenance of location GO:0051235 112 0.015
rhythmic behavior GO:0007622 2 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
gtp metabolic process GO:0046039 239 0.015
cell cycle phase transition GO:0044770 173 0.015
sequestering of metal ion GO:0051238 24 0.015
response to wounding GO:0009611 168 0.015
compound eye development GO:0048749 1 0.015
coenzyme metabolic process GO:0006732 65 0.015
cellular protein catabolic process GO:0044257 261 0.015
regulation of peptidase activity GO:0052547 180 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
atp metabolic process GO:0046034 176 0.015
regulation of multi organism process GO:0043900 157 0.015
sulfur compound metabolic process GO:0006790 101 0.015
intracellular protein transport GO:0006886 270 0.015
immune system development GO:0002520 195 0.015
regulation of protein kinase activity GO:0045859 289 0.015
carbohydrate metabolic process GO:0005975 207 0.015
carboxylic acid biosynthetic process GO:0046394 97 0.015
negative regulation of proteolysis GO:0045861 132 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
positive regulation of organelle organization GO:0010638 195 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
Human
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
regulation of endopeptidase activity GO:0052548 170 0.014
neurological system process GO:0050877 163 0.014
divalent inorganic cation transport GO:0072511 158 0.014
Human
actin mediated cell contraction GO:0070252 12 0.014
Human
central nervous system development GO:0007417 123 0.014
oocyte development GO:0048599 1 0.014
rho protein signal transduction GO:0007266 26 0.014
nucleotide biosynthetic process GO:0009165 109 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
mitochondrion organization GO:0007005 156 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
axon regeneration GO:0031103 1 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
ion homeostasis GO:0050801 230 0.014
cation homeostasis GO:0055080 189 0.014
neurogenesis GO:0022008 169 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
protein localization to nucleus GO:0034504 136 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
regulation of intracellular transport GO:0032386 195 0.014
long term memory GO:0007616 2 0.014
positive regulation of cell death GO:0010942 263 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
glycoprotein metabolic process GO:0009100 110 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
cell projection assembly GO:0030031 126 0.014
neuron projection regeneration GO:0031102 1 0.014
response to oxidative stress GO:0006979 121 0.014
regulation of locomotion GO:0040012 329 0.014
transmembrane transport GO:0055085 399 0.014
Human
anterior posterior axis specification GO:0009948 2 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
translation GO:0006412 132 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
positive regulation of defense response GO:0031349 87 0.013
positive regulation of immune response GO:0050778 159 0.013
anion transport GO:0006820 161 0.013
endocytosis GO:0006897 159 0.013
cytokine production GO:0001816 247 0.013
cell adhesion GO:0007155 325 0.013
regulation of cellular component movement GO:0051270 334 0.013
Human
defense response to other organism GO:0098542 129 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.013
cellular component disassembly GO:0022411 92 0.013
positive regulation of innate immune response GO:0045089 79 0.013
alcohol metabolic process GO:0006066 114 0.013
regulation of actin filament based process GO:0032970 141 0.013
Human
somatic muscle development GO:0007525 1 0.013
organic anion transport GO:0015711 103 0.013
neuroblast proliferation GO:0007405 4 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
phospholipid metabolic process GO:0006644 99 0.013
cilium organization GO:0044782 68 0.013
calcium ion transport GO:0006816 147 0.013
Human
negative regulation of protein processing GO:0010955 142 0.013
rna interference GO:0016246 4 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
protein polyubiquitination GO:0000209 110 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
multi organism cellular process GO:0044764 156 0.013
cell activation GO:0001775 213 0.013
response to axon injury GO:0048678 1 0.013
leukocyte activation GO:0045321 164 0.013
organic acid biosynthetic process GO:0016053 97 0.013
limbic system development GO:0021761 3 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
regulation of cell development GO:0060284 161 0.012
actin filament based movement GO:0030048 17 0.012
Human
regulation of protein catabolic process GO:0042176 155 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
activation of immune response GO:0002253 114 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
cardiovascular system development GO:0072358 262 0.012
neuron differentiation GO:0030182 138 0.012
protein ubiquitination GO:0016567 314 0.012
associative learning GO:0008306 1 0.012
cellular cation homeostasis GO:0030003 163 0.012
viral process GO:0016032 146 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
regulation of protein maturation GO:1903317 150 0.012
nuclear import GO:0051170 106 0.012
negative regulation of immune system process GO:0002683 136 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
response to nitrogen compound GO:1901698 184 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
calcium ion homeostasis GO:0055074 122 0.012
regulation of protein processing GO:0070613 150 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
positive regulation of immune system process GO:0002684 283 0.012
cell projection morphogenesis GO:0048858 129 0.012
peripheral nervous system development GO:0007422 2 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
cell growth GO:0016049 160 0.012
regulation of gtpase activity GO:0043087 180 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
cilium assembly GO:0042384 63 0.012
cellular protein complex assembly GO:0043623 188 0.012
mating GO:0007618 1 0.012
plasma membrane organization GO:0007009 115 0.012
protein maturation GO:0051604 233 0.012
cellular chemical homeostasis GO:0055082 180 0.012
membrane lipid metabolic process GO:0006643 53 0.012
regulation of binding GO:0051098 111 0.012
hemostasis GO:0007599 76 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.011
lipid transport GO:0006869 90 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
regulation of innate immune response GO:0045088 97 0.011
regulation of immune response GO:0050776 201 0.011
protein autophosphorylation GO:0046777 123 0.011
myeloid cell differentiation GO:0030099 117 0.011
hemopoiesis GO:0030097 180 0.011
viral life cycle GO:0019058 132 0.011
mrna metabolic process GO:0016071 175 0.011
positive regulation of cell cycle GO:0045787 140 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
regulation of cell motility GO:2000145 299 0.011
negative regulation of peptidase activity GO:0010466 91 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.011
oxidation reduction process GO:0055114 396 0.011
protein localization to membrane GO:0072657 160 0.011
neuron development GO:0048666 113 0.011
protein import GO:0017038 130 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
organ formation GO:0048645 3 0.011
positive regulation of protein transport GO:0051222 135 0.011
neurotransmitter secretion GO:0007269 4 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
sex determination GO:0007530 3 0.011
convergent extension GO:0060026 1 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
cellular response to external stimulus GO:0071496 111 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
microtubule based process GO:0007017 210 0.011
cellular amide metabolic process GO:0043603 69 0.011
visual behavior GO:0007632 2 0.011
metal ion homeostasis GO:0055065 169 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
rna processing GO:0006396 255 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
positive regulation of intracellular transport GO:0032388 104 0.010
melanin metabolic process GO:0006582 1 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
divalent metal ion transport GO:0070838 152 0.010
Human
positive regulation of secretion GO:0051047 116 0.010
regulation of response to wounding GO:1903034 101 0.010
ribose phosphate biosynthetic process GO:0046390 82 0.010
negative regulation of endopeptidase activity GO:0010951 84 0.010
coagulation GO:0050817 78 0.010
protein import into nucleus GO:0006606 104 0.010
cell cell signaling GO:0007267 155 0.010
epithelial cell proliferation GO:0050673 128 0.010
morphogenesis of embryonic epithelium GO:0016331 4 0.010
embryonic epithelial tube formation GO:0001838 4 0.010
somatic stem cell division GO:0048103 1 0.010
negative regulation of organelle organization GO:0010639 126 0.010
single organism cell adhesion GO:0098602 179 0.010

GCA disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.043
disease of metabolism DOID:0014667 295 0.033
muscular disease DOID:0080000 114 0.026
muscle tissue disease DOID:66 113 0.026
sensory system disease DOID:0050155 203 0.024
eye and adnexa disease DOID:1492 150 0.024
nervous system disease DOID:863 431 0.024
eye disease DOID:5614 149 0.024
bone disease DOID:0080001 88 0.023
connective tissue disease DOID:65 109 0.023
retinal disease DOID:5679 118 0.017
central nervous system disease DOID:331 186 0.014
myopathy DOID:423 104 0.014
inherited metabolic disorder DOID:655 242 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
retinal degeneration DOID:8466 89 0.013
organ system cancer DOID:0050686 164 0.012
neurodegenerative disease DOID:1289 102 0.011
neuropathy DOID:870 52 0.010