Homo sapiens

35 known processes

MBIP

MAP3K12 binding inhibitory protein 1

MBIP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone h3 acetylation GO:0043966 45 0.980
histone acetylation GO:0016573 93 0.797
peptidyl lysine modification GO:0018205 144 0.749
protein acetylation GO:0006473 116 0.647
histone modification GO:0016570 251 0.514
histone h4 acetylation GO:0043967 47 0.467
covalent chromatin modification GO:0016569 254 0.466
cellular amino acid metabolic process GO:0006520 116 0.419
protein acylation GO:0043543 138 0.402
cellular ketone metabolic process GO:0042180 80 0.360
neuron projection development GO:0031175 106 0.329
regulation of cellular amino acid metabolic process GO:0006521 6 0.324
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.320
histone h2a acetylation GO:0043968 12 0.295
internal protein amino acid acetylation GO:0006475 101 0.292
chromatin modification GO:0016568 298 0.263
amine metabolic process GO:0009308 44 0.263
positive regulation of cellular amine metabolic process GO:0033240 7 0.249
cell development GO:0048468 328 0.207
cellular component morphogenesis GO:0032989 314 0.204
nervous system development GO:0007399 293 0.202
regulation of histone acetylation GO:0035065 19 0.200
chromatin remodeling GO:0006338 55 0.191
regulation of cellular amine metabolic process GO:0033238 11 0.182
cellular amine metabolic process GO:0044106 41 0.171
positive regulation of catabolic process GO:0009896 310 0.168
single organism cellular localization GO:1902580 332 0.160
regulation of axon guidance GO:1902667 3 0.158
regulation of chromosome organization GO:0033044 103 0.155
single organism membrane organization GO:0044802 268 0.142
plasma membrane organization GO:0007009 115 0.129
internal peptidyl lysine acetylation GO:0018393 97 0.125
locomotory behavior GO:0007626 1 0.124
positive regulation of cellular component organization GO:0051130 376 0.117
cell morphogenesis GO:0000902 296 0.115
histone h4 k16 acetylation GO:0043984 14 0.114
cell projection organization GO:0030030 252 0.112
regulation of cell differentiation GO:0045595 393 0.110
vesicle organization GO:0016050 62 0.106
regulation of axon extension involved in axon guidance GO:0048841 2 0.103
protein localization to plasma membrane GO:0072659 93 0.102
growth GO:0040007 202 0.101
positive regulation of organelle organization GO:0010638 195 0.098
post embryonic development GO:0009791 2 0.098
positive regulation of chromatin modification GO:1903310 30 0.093
cell cell signaling GO:0007267 155 0.091
neurogenesis GO:0022008 169 0.088
negative regulation of protein metabolic process GO:0051248 391 0.087
oocyte differentiation GO:0009994 2 0.085
axon cargo transport GO:0008088 2 0.085
ubiquitin dependent protein catabolic process GO:0006511 206 0.084
membrane organization GO:0061024 292 0.084
regulation of chromatin modification GO:1903308 51 0.074
protein processing GO:0016485 226 0.073
autophagy GO:0006914 88 0.071
regulation of anatomical structure morphogenesis GO:0022603 286 0.070
cell projection morphogenesis GO:0048858 129 0.069
negative regulation of cellular protein metabolic process GO:0032269 353 0.063
endosome to lysosome transport GO:0008333 21 0.062
cell morphogenesis involved in differentiation GO:0000904 144 0.061
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.060
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.060
generation of neurons GO:0048699 152 0.060
endosomal transport GO:0016197 129 0.059
positive regulation of histone modification GO:0031058 29 0.059
regulation of chromatin organization GO:1902275 56 0.057
regulation of protein localization GO:0032880 296 0.056
regulation of histone modification GO:0031056 47 0.056
neuron differentiation GO:0030182 138 0.056
cell part morphogenesis GO:0032990 137 0.055
stress activated protein kinase signaling cascade GO:0031098 94 0.055
vesicle mediated transport GO:0016192 371 0.055
negative regulation of cell cycle GO:0045786 193 0.054
protein maturation GO:0051604 233 0.054
nucleoside triphosphate metabolic process GO:0009141 422 0.053
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.053
regulation of growth GO:0040008 165 0.051
protein localization to membrane GO:0072657 160 0.049
negative regulation of protein catabolic process GO:0042177 59 0.049
regulation of protein acetylation GO:1901983 25 0.049
histone methylation GO:0016571 60 0.049
purine nucleoside triphosphate metabolic process GO:0009144 412 0.048
protein catabolic process GO:0030163 325 0.047
endomembrane system organization GO:0010256 196 0.047
developmental growth GO:0048589 48 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.046
regulation of cell growth GO:0001558 135 0.045
regulation of cellular ketone metabolic process GO:0010565 50 0.045
inner ear morphogenesis GO:0042472 4 0.044
cell cycle checkpoint GO:0000075 117 0.042
photoreceptor cell differentiation GO:0046530 2 0.041
negative regulation of protein processing GO:0010955 142 0.041
regulation of peptidyl lysine acetylation GO:2000756 22 0.040
retinal ganglion cell axon guidance GO:0031290 2 0.040
regulation of mapk cascade GO:0043408 262 0.038
reproductive system development GO:0061458 56 0.038
macromolecule methylation GO:0043414 97 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
protein localization to organelle GO:0033365 280 0.037
histone h4 k8 acetylation GO:0043982 15 0.037
taxis GO:0042330 157 0.036
regulation of jnk cascade GO:0046328 73 0.036
oocyte development GO:0048599 1 0.036
negative regulation of phosphate metabolic process GO:0045936 267 0.036
positive regulation of transferase activity GO:0051347 227 0.036
oogenesis GO:0048477 2 0.036
positive regulation of hydrolase activity GO:0051345 331 0.035
positive regulation of autophagy GO:0010508 24 0.035
cell growth GO:0016049 160 0.035
stress activated mapk cascade GO:0051403 93 0.035
neuron development GO:0048666 113 0.035
regulation of cell projection organization GO:0031344 107 0.034
neuromuscular junction development GO:0007528 3 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.033
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.033
regulation of proteolysis GO:0030162 293 0.033
regulation of cellular component movement GO:0051270 334 0.033
protein alkylation GO:0008213 74 0.033
chromatin organization GO:0006325 351 0.033
circadian behavior GO:0048512 2 0.032
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.031
protein modification by small protein removal GO:0070646 92 0.031
regulation of autophagy GO:0010506 52 0.031
positive regulation of cell proliferation GO:0008284 301 0.031
regulation of cell morphogenesis GO:0022604 153 0.030
negative regulation of cell cycle process GO:0010948 121 0.030
response to hormone GO:0009725 175 0.030
response to abiotic stimulus GO:0009628 336 0.030
nerve development GO:0021675 4 0.029
female gamete generation GO:0007292 2 0.029
homeostasis of number of cells GO:0048872 40 0.029
negative regulation of axon extension GO:0030517 2 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.029
negative regulation of developmental process GO:0051093 247 0.029
neuron projection morphogenesis GO:0048812 50 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.028
purine nucleoside triphosphate catabolic process GO:0009146 392 0.028
ribonucleoside triphosphate metabolic process GO:0009199 412 0.028
regulation of neural precursor cell proliferation GO:2000177 4 0.028
organelle localization GO:0051640 84 0.028
regulation of protein kinase activity GO:0045859 289 0.027
proteasomal protein catabolic process GO:0010498 176 0.027
positive regulation of developmental process GO:0051094 314 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.027
epithelium development GO:0060429 227 0.027
regulation of stress activated mapk cascade GO:0032872 84 0.026
histone h3 k4 methylation GO:0051568 27 0.026
cytoskeleton dependent intracellular transport GO:0030705 21 0.026
cerebral cortex cell migration GO:0021795 3 0.026
regulation of kinase activity GO:0043549 314 0.025
purine ribonucleotide catabolic process GO:0009154 404 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
establishment of protein localization to plasma membrane GO:0090002 68 0.024
cellular macromolecule catabolic process GO:0044265 380 0.024
negative regulation of growth GO:0045926 97 0.024
negative regulation of cell cycle phase transition GO:1901988 89 0.024
cytokine production GO:0001816 247 0.024
chemical homeostasis GO:0048878 306 0.024
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
cytoplasmic transport GO:0016482 379 0.023
cellular protein catabolic process GO:0044257 261 0.023
cranial nerve development GO:0021545 4 0.023
lysosomal transport GO:0007041 33 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
determination of adult lifespan GO:0008340 2 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
peptidyl lysine methylation GO:0018022 37 0.023
secretion by cell GO:0032940 226 0.023
vacuolar transport GO:0007034 34 0.022
negative regulation of cell proliferation GO:0008285 228 0.022
negative regulation of cellular catabolic process GO:0031330 83 0.022
central nervous system development GO:0007417 123 0.021
modification dependent protein catabolic process GO:0019941 209 0.021
mitotic sister chromatid segregation GO:0000070 53 0.021
axonogenesis GO:0007409 31 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
organic hydroxy compound metabolic process GO:1901615 147 0.021
modification dependent macromolecule catabolic process GO:0043632 212 0.020
hindbrain development GO:0030902 3 0.020
lipid homeostasis GO:0055088 39 0.020
regulation of locomotion GO:0040012 329 0.020
mitotic cell cycle checkpoint GO:0007093 68 0.020
regulation of protein catabolic process GO:0042176 155 0.020
response to nitrogen compound GO:1901698 184 0.020
negative regulation of cell differentiation GO:0045596 171 0.020
establishment of vesicle localization GO:0051650 23 0.020
negative regulation of protein maturation GO:1903318 142 0.020
actin filament based process GO:0030029 224 0.019
regulation of neurogenesis GO:0050767 82 0.019
cell cycle phase transition GO:0044770 173 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
developmental cell growth GO:0048588 18 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
regulation of protein serine threonine kinase activity GO:0071900 179 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.019
lymphocyte activation GO:0046649 133 0.018
renal sodium ion absorption GO:0070294 2 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
chromosome segregation GO:0007059 114 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
regulation of cellular response to stress GO:0080135 244 0.018
cellular response to external stimulus GO:0071496 111 0.018
establishment of protein localization to membrane GO:0090150 121 0.018
methylation GO:0032259 106 0.018
brain development GO:0007420 97 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
maintenance of location GO:0051235 112 0.017
negative regulation of cell death GO:0060548 345 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
compound eye development GO:0048749 1 0.017
regulation of cell activation GO:0050865 125 0.017
mitotic cell cycle GO:0000278 326 0.017
jnk cascade GO:0007254 80 0.016
head development GO:0060322 108 0.016
regulation of synaptic transmission dopaminergic GO:0032225 4 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
microtubule based transport GO:0010970 21 0.016
peptidyl lysine acetylation GO:0018394 101 0.016
protein methylation GO:0006479 74 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
endocytosis GO:0006897 159 0.016
distal tubule development GO:0072017 4 0.016
regulation of cell cycle process GO:0010564 266 0.016
regulation of mitotic cell cycle phase transition GO:1901990 118 0.016
regulation of transferase activity GO:0051338 355 0.015
histone lysine methylation GO:0034968 50 0.015
mapk cascade GO:0000165 288 0.015
anterograde axon cargo transport GO:0008089 1 0.015
positive regulation of histone acetylation GO:0035066 11 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.015
positive regulation of kinase activity GO:0033674 204 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
immune response GO:0006955 307 0.015
histone h4 k5 acetylation GO:0043981 15 0.015
erythrocyte development GO:0048821 3 0.015
regulation of cell cycle GO:0051726 393 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
reproductive process GO:0022414 106 0.015
negative regulation of catabolic process GO:0009895 104 0.015
multicellular organismal aging GO:0010259 3 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.014
developmental growth involved in morphogenesis GO:0060560 23 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
mitotic nuclear division GO:0007067 119 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
regulation of protein maturation GO:1903317 150 0.014
signal transduction in response to dna damage GO:0042770 57 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
purine ribonucleotide biosynthetic process GO:0009152 79 0.014
rhythmic behavior GO:0007622 2 0.014
synaptic transmission GO:0007268 61 0.014
cell division GO:0051301 168 0.014
neuron projection extension GO:1990138 14 0.014
negative regulation of protein modification process GO:0031400 200 0.013
regulation of neuron projection development GO:0010975 57 0.013
axon extension involved in axon guidance GO:0048846 5 0.013
response to oxygen containing compound GO:1901700 369 0.013
maintenance of location in cell GO:0051651 62 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
regulation of cell development GO:0060284 161 0.013
ribonucleotide biosynthetic process GO:0009260 81 0.013
mating GO:0007618 1 0.013
regulation of neuron differentiation GO:0045664 70 0.013
negative regulation of kinase activity GO:0033673 106 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
regulation of cell cycle phase transition GO:1901987 126 0.012
purine ribonucleoside metabolic process GO:0046128 437 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
mitotic cell cycle process GO:1903047 286 0.012
reproduction GO:0000003 63 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
regulation of intracellular transport GO:0032386 195 0.012
response to organonitrogen compound GO:0010243 156 0.012
alcohol metabolic process GO:0006066 114 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
protein ubiquitination GO:0016567 314 0.012
dephosphorylation GO:0016311 209 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
system process GO:0003008 349 0.012
ribose phosphate biosynthetic process GO:0046390 82 0.012
peripheral nervous system development GO:0007422 2 0.012
response to cytokine GO:0034097 232 0.012
memory GO:0007613 3 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
associative learning GO:0008306 1 0.012
regulation of cell division GO:0051302 116 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
intermediate filament based process GO:0045103 17 0.012
behavior GO:0007610 112 0.012
regulation of protein processing GO:0070613 150 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
response to organic cyclic compound GO:0014070 204 0.012
rho protein signal transduction GO:0007266 26 0.012
actin filament bundle assembly GO:0051017 54 0.011
negative regulation of organelle organization GO:0010639 126 0.011
protein targeting to nucleus GO:0044744 104 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
negative regulation of transferase activity GO:0051348 124 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
neuroblast proliferation GO:0007405 4 0.011
nucleoside phosphate biosynthetic process GO:1901293 109 0.011
secretion GO:0046903 254 0.011
positive regulation of immune system process GO:0002684 283 0.011
regulation of protein localization to plasma membrane GO:1903076 40 0.011
nitrogen compound transport GO:0071705 191 0.011
steroid metabolic process GO:0008202 94 0.011
actin cytoskeleton organization GO:0030036 207 0.011
response to lipid GO:0033993 206 0.011
blastocyst development GO:0001824 3 0.011
neuromuscular synaptic transmission GO:0007274 5 0.011
protein k33 linked ubiquitination GO:1990390 1 0.011
cellular response to nutrient levels GO:0031669 69 0.011
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.011
protein homooligomerization GO:0051260 100 0.011
leukocyte activation GO:0045321 164 0.010
nucleotide biosynthetic process GO:0009165 109 0.010
sex differentiation GO:0007548 45 0.010
regulation of cellular component size GO:0032535 82 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
morphogenesis of a polarized epithelium GO:0001738 3 0.010
vesicle localization GO:0051648 26 0.010
adult locomotory behavior GO:0008344 1 0.010
immune system development GO:0002520 195 0.010
microtubule based process GO:0007017 210 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
renal sodium ion transport GO:0003096 2 0.010
purine nucleotide biosynthetic process GO:0006164 84 0.010
response to estrogen GO:0043627 47 0.010
nuclear transport GO:0051169 179 0.010
regulation of cell motility GO:2000145 299 0.010

MBIP disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.045
disease of cellular proliferation DOID:14566 174 0.045
central nervous system disease DOID:331 186 0.040
nervous system disease DOID:863 431 0.040
sensory system disease DOID:0050155 203 0.032
eye and adnexa disease DOID:1492 150 0.032
eye disease DOID:5614 149 0.032
organ system cancer DOID:0050686 164 0.023
bone development disease DOID:0080006 55 0.021
bone disease DOID:0080001 88 0.021
musculoskeletal system disease DOID:17 223 0.021
connective tissue disease DOID:65 109 0.021
brain disease DOID:936 73 0.019
disease of metabolism DOID:0014667 295 0.015
inherited metabolic disorder DOID:655 242 0.014
retinal disease DOID:5679 118 0.011
endocrine gland cancer DOID:170 26 0.011
neurodegenerative disease DOID:1289 102 0.010