Homo sapiens

30 known processes

LGR5

leucine-rich repeat containing G protein-coupled receptor 5

(Aliases: MGC117008,GRP49,GPR67,GPR49,HG38,FEX)

LGR5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.092
cellular ketone metabolic process GO:0042180 80 0.091
system process GO:0003008 349 0.084
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.082
regulation of cellular amine metabolic process GO:0033238 11 0.074
post embryonic development GO:0009791 2 0.074
amine metabolic process GO:0009308 44 0.070
cellular amine metabolic process GO:0044106 41 0.069
regulation of cell differentiation GO:0045595 393 0.068
regulation of cellular amino acid metabolic process GO:0006521 6 0.065
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.063
nervous system development GO:0007399 293 0.063
epithelium development GO:0060429 227 0.062
negative regulation of multicellular organismal process GO:0051241 317 0.061
cell development GO:0048468 328 0.060
ion transmembrane transport GO:0034220 338 0.059
circulatory system development GO:0072359 262 0.058
positive regulation of cellular amine metabolic process GO:0033240 7 0.056
cellular component morphogenesis GO:0032989 314 0.055
segmentation GO:0035282 4 0.055
locomotory behavior GO:0007626 1 0.053
regulation of cellular component movement GO:0051270 334 0.052
Human
biological adhesion GO:0022610 331 0.052
transmembrane transport GO:0055085 399 0.052
positive regulation of cellular component organization GO:0051130 376 0.050
cell morphogenesis GO:0000902 296 0.050
small gtpase mediated signal transduction GO:0007264 78 0.049
cardiovascular system development GO:0072358 262 0.049
cellular response to endogenous stimulus GO:0071495 336 0.048
organophosphate catabolic process GO:0046434 430 0.048
purine nucleotide catabolic process GO:0006195 405 0.048
regulation of cell motility GO:2000145 299 0.047
Human
negative regulation of protein metabolic process GO:0051248 391 0.047
negative regulation of developmental process GO:0051093 247 0.046
ras protein signal transduction GO:0007265 73 0.046
anatomical structure formation involved in morphogenesis GO:0048646 284 0.045
cell projection organization GO:0030030 252 0.045
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.045
cell adhesion GO:0007155 325 0.045
organ morphogenesis GO:0009887 147 0.045
positive regulation of developmental process GO:0051094 314 0.045
regulation of locomotion GO:0040012 329 0.044
Human
oogenesis GO:0048477 2 0.044
nucleoside triphosphate metabolic process GO:0009141 422 0.044
positive regulation of phosphorylation GO:0042327 394 0.044
purine ribonucleotide catabolic process GO:0009154 404 0.044
purine ribonucleoside metabolic process GO:0046128 437 0.044
actin filament based process GO:0030029 224 0.044
glycosyl compound catabolic process GO:1901658 413 0.044
multicellular organismal aging GO:0010259 3 0.044
female gamete generation GO:0007292 2 0.043
response to oxygen containing compound GO:1901700 369 0.043
enzyme linked receptor protein signaling pathway GO:0007167 303 0.043
purine containing compound catabolic process GO:0072523 411 0.043
regulation of anatomical structure morphogenesis GO:0022603 286 0.043
ribonucleoside catabolic process GO:0042454 406 0.042
regulation of cell migration GO:0030334 289 0.042
Human
lipid metabolic process GO:0006629 381 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.041
negative regulation of catalytic activity GO:0043086 335 0.041
positive regulation of cell proliferation GO:0008284 301 0.041
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
ribonucleotide catabolic process GO:0009261 405 0.040
ribonucleoside triphosphate metabolic process GO:0009199 412 0.040
cation transport GO:0006812 331 0.039
positive regulation of cell differentiation GO:0045597 211 0.039
hindbrain development GO:0030902 3 0.039
negative regulation of cell death GO:0060548 345 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.039
regulation of cell cycle GO:0051726 393 0.039
purine nucleoside triphosphate metabolic process GO:0009144 412 0.039
negative regulation of phosphorus metabolic process GO:0010563 267 0.038
determination of adult lifespan GO:0008340 2 0.038
nucleoside catabolic process GO:0009164 408 0.038
purine nucleoside catabolic process GO:0006152 398 0.038
purine nucleoside triphosphate catabolic process GO:0009146 392 0.038
nucleoside phosphate catabolic process GO:1901292 412 0.037
nucleoside triphosphate catabolic process GO:0009143 394 0.037
negative regulation of phosphate metabolic process GO:0045936 267 0.037
positive regulation of hydrolase activity GO:0051345 331 0.037
membrane organization GO:0061024 292 0.037
negative regulation of cellular protein metabolic process GO:0032269 353 0.037
morphogenesis of embryonic epithelium GO:0016331 4 0.037
purine ribonucleoside catabolic process GO:0046130 398 0.037
regulation of transferase activity GO:0051338 355 0.036
cellular lipid metabolic process GO:0044255 303 0.036
positive regulation of catabolic process GO:0009896 310 0.036
positive regulation of transport GO:0051050 336 0.036
cytoplasmic transport GO:0016482 379 0.036
response to abiotic stimulus GO:0009628 336 0.036
single organism cellular localization GO:1902580 332 0.036
nerve development GO:0021675 4 0.036
negative regulation of cell proliferation GO:0008285 228 0.035
epithelial cell differentiation GO:0030855 141 0.035
signal transduction by phosphorylation GO:0023014 297 0.035
nucleotide catabolic process GO:0009166 408 0.035
anterior posterior axis specification GO:0009948 2 0.034
regulation of nucleotide metabolic process GO:0006140 269 0.034
rho protein signal transduction GO:0007266 26 0.033
chemical homeostasis GO:0048878 306 0.033
negative regulation of programmed cell death GO:0043069 321 0.033
mapk cascade GO:0000165 288 0.033
regulation of mapk cascade GO:0043408 262 0.033
blastoderm segmentation GO:0007350 2 0.033
organ formation GO:0048645 3 0.033
protein localization to organelle GO:0033365 280 0.033
regulation of protein localization GO:0032880 296 0.032
single organism membrane organization GO:0044802 268 0.032
regulation of proteolysis GO:0030162 293 0.032
vesicle mediated transport GO:0016192 371 0.032
cation transmembrane transport GO:0098655 238 0.032
positive regulation of cellular catabolic process GO:0031331 284 0.031
wnt signaling pathway GO:0016055 156 0.031
immune response GO:0006955 307 0.030
mitotic cell cycle GO:0000278 326 0.030
regulation of protein kinase activity GO:0045859 289 0.030
cellular response to oxygen containing compound GO:1901701 276 0.030
generation of neurons GO:0048699 152 0.030
intracellular protein transport GO:0006886 270 0.030
secretion by cell GO:0032940 226 0.030
regeneration GO:0031099 4 0.030
regulation of cellular component biogenesis GO:0044087 281 0.030
canonical wnt signaling pathway GO:0060070 116 0.030
negative regulation of transport GO:0051051 176 0.029
positive regulation of protein phosphorylation GO:0001934 313 0.029
cell fate determination GO:0001709 3 0.029
negative regulation of apoptotic process GO:0043066 316 0.029
guanosine containing compound metabolic process GO:1901068 244 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.028
regulation of nucleoside metabolic process GO:0009118 209 0.028
regulation of purine nucleotide metabolic process GO:1900542 264 0.028
regulation of nucleotide catabolic process GO:0030811 205 0.028
inner ear morphogenesis GO:0042472 4 0.028
neuromuscular junction development GO:0007528 3 0.028
gtp catabolic process GO:0006184 237 0.028
response to organic cyclic compound GO:0014070 204 0.028
regulation of kinase activity GO:0043549 314 0.028
metal ion transport GO:0030001 272 0.028
regulation of establishment of protein localization GO:0070201 242 0.028
motor neuron axon guidance GO:0008045 2 0.028
neuron differentiation GO:0030182 138 0.028
peripheral nervous system development GO:0007422 2 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.027
anion transport GO:0006820 161 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
cranial nerve development GO:0021545 4 0.027
regulation of cell cycle process GO:0010564 266 0.027
neurogenesis GO:0022008 169 0.027
blood vessel morphogenesis GO:0048514 162 0.027
vasculature development GO:0001944 181 0.027
chemotaxis GO:0006935 157 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
regulation of intracellular transport GO:0032386 195 0.026
regulation of purine nucleotide catabolic process GO:0033121 205 0.026
mitotic cell cycle process GO:1903047 286 0.026
negative regulation of cell differentiation GO:0045596 171 0.026
regulation of protein transport GO:0051223 213 0.026
adult locomotory behavior GO:0008344 1 0.026
cellular macromolecular complex assembly GO:0034622 324 0.026
blood vessel development GO:0001568 172 0.026
regulation of cell adhesion GO:0030155 166 0.026
blood circulation GO:0008015 113 0.026
nitrogen compound transport GO:0071705 191 0.025
limbic system development GO:0021761 3 0.025
regulation of cell development GO:0060284 161 0.025
positive regulation of cell death GO:0010942 263 0.025
secretion GO:0046903 254 0.025
regulation of cellular response to stress GO:0080135 244 0.025
defense response GO:0006952 315 0.025
forelimb morphogenesis GO:0035136 4 0.025
guanosine containing compound catabolic process GO:1901069 239 0.025
tissue morphogenesis GO:0048729 96 0.025
inorganic cation transmembrane transport GO:0098662 194 0.025
gtp metabolic process GO:0046039 239 0.024
negative regulation of protein modification process GO:0031400 200 0.024
growth GO:0040007 202 0.024
regulation of wnt signaling pathway GO:0030111 123 0.024
forebrain generation of neurons GO:0021872 3 0.024
positive regulation of synaptic transmission GO:0050806 4 0.024
protein catabolic process GO:0030163 325 0.024
organonitrogen compound biosynthetic process GO:1901566 200 0.024
cell morphogenesis involved in differentiation GO:0000904 144 0.024
response to growth factor GO:0070848 205 0.024
cellular response to dna damage stimulus GO:0006974 379 0.024
response to biotic stimulus GO:0009607 276 0.024
chromatin organization GO:0006325 351 0.024
neuron fate commitment GO:0048663 2 0.024
regulation of ion transport GO:0043269 189 0.024
taxis GO:0042330 157 0.024
epithelium migration GO:0090132 119 0.024
protein processing GO:0016485 226 0.024
protein maturation GO:0051604 233 0.023
regulation of gtp catabolic process GO:0033124 180 0.023
positive regulation of cell motility GO:2000147 177 0.023
Human
regulation of actin filament based process GO:0032970 141 0.023
memory GO:0007613 3 0.023
regulation of gtpase activity GO:0043087 180 0.023
actin cytoskeleton organization GO:0030036 207 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
regulation of secretion GO:0051046 194 0.023
lipid biosynthetic process GO:0008610 177 0.023
cell cell signaling GO:0007267 155 0.023
tube development GO:0035295 125 0.023
positive regulation of mapk cascade GO:0043410 190 0.023
circulatory system process GO:0003013 113 0.023
cardiac muscle cell contraction GO:0086003 4 0.023
cellular homeostasis GO:0019725 196 0.023
positive regulation of immune system process GO:0002684 283 0.023
inorganic ion transmembrane transport GO:0098660 231 0.023
neurological system process GO:0050877 163 0.023
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
protein targeting GO:0006605 187 0.023
regulation of cytokine production GO:0001817 232 0.023
regulation of hormone levels GO:0010817 125 0.023
negative regulation of phosphorylation GO:0042326 174 0.023
positive regulation of locomotion GO:0040017 186 0.023
Human
embryonic epithelial tube formation GO:0001838 4 0.022
regulation of mitotic cell cycle GO:0007346 189 0.022
dephosphorylation GO:0016311 209 0.022
neuron development GO:0048666 113 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
response to lipid GO:0033993 206 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
ameboidal type cell migration GO:0001667 135 0.022
response to other organism GO:0051707 261 0.022
regulation of growth GO:0040008 165 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
positive regulation of organelle organization GO:0010638 195 0.022
single organism cell adhesion GO:0098602 179 0.022
positive regulation of programmed cell death GO:0043068 249 0.022
regulation of canonical wnt signaling pathway GO:0060828 88 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
regulation of response to external stimulus GO:0032101 222 0.022
cell part morphogenesis GO:0032990 137 0.022
startle response GO:0001964 3 0.022
chromatin modification GO:0016568 298 0.022
specification of organ identity GO:0010092 3 0.021
positive regulation of nucleotide catabolic process GO:0030813 185 0.021
metencephalon development GO:0022037 2 0.021
positive regulation of transferase activity GO:0051347 227 0.021
cell growth GO:0016049 160 0.021
regulation of cytoplasmic transport GO:1903649 149 0.021
cytokine production GO:0001816 247 0.021
nuclear transport GO:0051169 179 0.021
cellular response to organic cyclic compound GO:0071407 127 0.021
neurotransmitter secretion GO:0007269 4 0.021
positive regulation of kinase activity GO:0033674 204 0.021
monocarboxylic acid metabolic process GO:0032787 185 0.021
negative regulation of cell cycle GO:0045786 193 0.021
neuron projection development GO:0031175 106 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.021
ion homeostasis GO:0050801 230 0.021
negative regulation of locomotion GO:0040013 118 0.021
immune system development GO:0002520 195 0.021
g protein coupled receptor signaling pathway GO:0007186 207 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
apoptotic signaling pathway GO:0097190 268 0.021
endomembrane system organization GO:0010256 196 0.021
somatic stem cell maintenance GO:0035019 4 0.021
tripartite regional subdivision GO:0007351 2 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.021
actin filament based movement GO:0030048 17 0.021
regulation of cytoskeleton organization GO:0051493 177 0.020
positive regulation of nucleoside metabolic process GO:0045979 186 0.020
epithelial cell migration GO:0010631 119 0.020
nucleocytoplasmic transport GO:0006913 176 0.020
cell projection morphogenesis GO:0048858 129 0.020
response to wounding GO:0009611 168 0.020
embryonic camera type eye development GO:0031076 2 0.020
positive regulation of protein kinase activity GO:0045860 190 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
negative regulation of cell migration GO:0030336 102 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
photoreceptor cell differentiation GO:0046530 2 0.020
regulation of secretion by cell GO:1903530 177 0.020
hemopoiesis GO:0030097 180 0.020
head development GO:0060322 108 0.020
tissue migration GO:0090130 119 0.020
regulation of protein serine threonine kinase activity GO:0071900 179 0.020
protein localization to membrane GO:0072657 160 0.019
embryonic forelimb morphogenesis GO:0035115 4 0.019
hematopoietic or lymphoid organ development GO:0048534 186 0.019
skeletal system development GO:0001501 79 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
innate immune response GO:0045087 178 0.019
protein ubiquitination GO:0016567 314 0.019
negative regulation of protein phosphorylation GO:0001933 140 0.019
oxidation reduction process GO:0055114 396 0.019
spermatid differentiation GO:0048515 4 0.019
carbohydrate metabolic process GO:0005975 207 0.019
oocyte development GO:0048599 1 0.019
regulation of cell growth GO:0001558 135 0.019
muscle contraction GO:0006936 73 0.019
brain development GO:0007420 97 0.019
neuroblast proliferation GO:0007405 4 0.019
circadian behavior GO:0048512 2 0.019
protein localization to nucleus GO:0034504 136 0.019
regulation of synaptic plasticity GO:0048167 3 0.019
negative regulation of cellular component movement GO:0051271 106 0.019
rhythmic behavior GO:0007622 2 0.019
ossification GO:0001503 121 0.019
oocyte differentiation GO:0009994 2 0.019
microtubule based process GO:0007017 210 0.019
pituitary gland development GO:0021983 2 0.019
regulation of membrane potential GO:0042391 95 0.019
response to external biotic stimulus GO:0043207 261 0.018
histone modification GO:0016570 251 0.018
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
epidermis morphogenesis GO:0048730 3 0.018
cellular protein catabolic process GO:0044257 261 0.018
cation homeostasis GO:0055080 189 0.018
regulation of small gtpase mediated signal transduction GO:0051056 156 0.018
regulation of neurotransmitter secretion GO:0046928 3 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
regulation of peptidase activity GO:0052547 180 0.018
positive regulation of cellular component movement GO:0051272 181 0.018
Human
somitogenesis GO:0001756 2 0.018
actin mediated cell contraction GO:0070252 12 0.018
covalent chromatin modification GO:0016569 254 0.018
positive regulation of gtp catabolic process GO:0033126 166 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
central nervous system development GO:0007417 123 0.018
morphogenesis of a polarized epithelium GO:0001738 3 0.018
embryonic viscerocranium morphogenesis GO:0048703 1 0.018
regulation of endopeptidase activity GO:0052548 170 0.018
metal ion homeostasis GO:0055065 169 0.018
salivary gland morphogenesis GO:0007435 4 0.018
spinal cord development GO:0021510 4 0.018
response to organonitrogen compound GO:0010243 156 0.018
epithelial cell proliferation GO:0050673 128 0.018
organic hydroxy compound metabolic process GO:1901615 147 0.018
positive regulation of cytokine production GO:0001819 167 0.018
regulation of multi organism process GO:0043900 157 0.018
plasma membrane organization GO:0007009 115 0.017
positive regulation of cellular component biogenesis GO:0044089 158 0.017
positive regulation of cell migration GO:0030335 172 0.017
Human
regulation of protein catabolic process GO:0042176 155 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
positive regulation of gtpase activity GO:0043547 166 0.017
maintenance of location GO:0051235 112 0.017
muscle system process GO:0003012 81 0.017
compound eye development GO:0048749 1 0.017
sex determination GO:0007530 3 0.017
peptidyl tyrosine phosphorylation GO:0018108 170 0.017
response to nitrogen compound GO:1901698 184 0.017
regulation of epithelial cell proliferation GO:0050678 113 0.017
regulation of immune response GO:0050776 201 0.017
cerebellum development GO:0021549 2 0.017
spermatid development GO:0007286 4 0.017
regulation of ras protein signal transduction GO:0046578 155 0.017
forebrain regionalization GO:0021871 3 0.017
retinal ganglion cell axon guidance GO:0031290 2 0.017
stem cell differentiation GO:0048863 93 0.017
sequestering of calcium ion GO:0051208 17 0.017
regulation of protein maturation GO:1903317 150 0.017
establishment of protein localization to membrane GO:0090150 121 0.017
tissue regeneration GO:0042246 3 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.017
cell substrate adhesion GO:0031589 132 0.017
osteoblast differentiation GO:0001649 92 0.017
negative regulation of wnt signaling pathway GO:0030178 69 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
positive regulation of protein transport GO:0051222 135 0.017
axis elongation GO:0003401 4 0.017
divalent metal ion transport GO:0070838 152 0.016
embryo development GO:0009790 123 0.016
small molecule biosynthetic process GO:0044283 157 0.016
cardiac muscle contraction GO:0060048 34 0.016
reactive oxygen species biosynthetic process GO:1903409 4 0.016
glial cell migration GO:0008347 4 0.016
neural tube formation GO:0001841 3 0.016
endodermal cell fate commitment GO:0001711 4 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
divalent inorganic cation transport GO:0072511 158 0.016
protein oligomerization GO:0051259 173 0.016
calcium ion transport GO:0006816 147 0.016
cellular protein complex assembly GO:0043623 188 0.016
nucleoside monophosphate metabolic process GO:0009123 191 0.016
regulation of protein processing GO:0070613 150 0.016
cell division GO:0051301 168 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
positive regulation of ras gtpase activity GO:0032320 117 0.016
cellular response to nitrogen compound GO:1901699 144 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
organelle assembly GO:0070925 176 0.016
regulation of ras gtpase activity GO:0032318 128 0.016
angiogenesis GO:0001525 147 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
forebrain neuron differentiation GO:0021879 3 0.016
protein import GO:0017038 130 0.016
neural crest cell development GO:0014032 3 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
hair follicle morphogenesis GO:0031069 2 0.016
associative learning GO:0008306 1 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.016
regulation of protein complex assembly GO:0043254 147 0.016
behavior GO:0007610 112 0.016
negative regulation of growth GO:0045926 97 0.016
regulation of actin cytoskeleton organization GO:0032956 116 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
heart formation GO:0060914 2 0.015
single organismal cell cell adhesion GO:0016337 148 0.015
stem cell division GO:0017145 2 0.015
cell cycle phase transition GO:0044770 173 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
response to hormone GO:0009725 175 0.015
endodermal cell fate specification GO:0001714 4 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
reactive nitrogen species metabolic process GO:2001057 3 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
striated muscle contraction GO:0006941 52 0.015
response to cytokine GO:0034097 232 0.015
negative regulation of cell motility GO:2000146 104 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
hindlimb morphogenesis GO:0035137 2 0.015
cellular response to lipid GO:0071396 127 0.015
sequestering of metal ion GO:0051238 24 0.015
regulation of transmembrane transport GO:0034762 139 0.015
negative regulation of protein processing GO:0010955 142 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
positive regulation of hormone biosynthetic process GO:0046886 4 0.015
heart development GO:0007507 95 0.015
organic anion transport GO:0015711 103 0.015
cellular ion homeostasis GO:0006873 168 0.015
peptidyl tyrosine modification GO:0018212 170 0.015
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.015
embryonic morphogenesis GO:0048598 85 0.015
reproductive process GO:0022414 106 0.015
Human
cellular chemical homeostasis GO:0055082 180 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.015
cellular response to organonitrogen compound GO:0071417 124 0.014
positive regulation of proteolysis GO:0045862 142 0.014
atp metabolic process GO:0046034 176 0.014
negative regulation of cell growth GO:0030308 83 0.014
regulation of homeostatic process GO:0032844 121 0.014
cell activation GO:0001775 213 0.014
primary neural tube formation GO:0014020 3 0.014
immune effector process GO:0002252 159 0.014
protein targeting to nucleus GO:0044744 104 0.014
regulation of metal ion transport GO:0010959 120 0.014
tube morphogenesis GO:0035239 95 0.014
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.014
glycoprotein metabolic process GO:0009100 110 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
response to axon injury GO:0048678 1 0.014
renal system development GO:0072001 63 0.014
skin development GO:0043588 76 0.014
regulation of dna metabolic process GO:0051052 153 0.014
nuclear import GO:0051170 106 0.014
positive regulation of cell development GO:0010720 92 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.014
monovalent inorganic cation transport GO:0015672 128 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
response to fungus GO:0009620 4 0.014
negative regulation of gliogenesis GO:0014014 3 0.014
mating GO:0007618 1 0.014
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.014
establishment of planar polarity GO:0001736 3 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
tube closure GO:0060606 3 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
cellular metal ion homeostasis GO:0006875 146 0.014
negative regulation of organelle organization GO:0010639 126 0.014
morphogenesis of an epithelium GO:0002009 60 0.014
negative regulation of proteolysis GO:0045861 132 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
receptor metabolic process GO:0043112 81 0.014
regulation of binding GO:0051098 111 0.014
regulation of axon guidance GO:1902667 3 0.014
endothelial cell migration GO:0043542 86 0.014
establishment of tissue polarity GO:0007164 3 0.014
cell type specific apoptotic process GO:0097285 125 0.014
embryonic eye morphogenesis GO:0048048 2 0.014

LGR5 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.038
disease of metabolism DOID:0014667 295 0.030
sensory system disease DOID:0050155 203 0.028
nervous system disease DOID:863 431 0.028
inherited metabolic disorder DOID:655 242 0.024
cancer DOID:162 167 0.021
disease of cellular proliferation DOID:14566 174 0.021
organ system cancer DOID:0050686 164 0.019
central nervous system disease DOID:331 186 0.019
connective tissue disease DOID:65 109 0.017
bone disease DOID:0080001 88 0.017
muscular disease DOID:0080000 114 0.017
muscle tissue disease DOID:66 113 0.017
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.016
cardiovascular system disease DOID:1287 106 0.016