Homo sapiens

48 known processes

RPS6KB2

ribosomal protein S6 kinase, 70kDa, polypeptide 2

(Aliases: P70-beta-1,p70S6Kb,P70-beta-2,S6K-beta2,STK14B,p70(S6K)-beta,SRK,KLS,S6K2,P70-beta)

RPS6KB2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organophosphate biosynthetic process GO:0090407 163 0.095
cellular amine metabolic process GO:0044106 41 0.079
regulation of cellular response to stress GO:0080135 244 0.073
Worm Fly
amine metabolic process GO:0009308 44 0.072
positive regulation of protein phosphorylation GO:0001934 313 0.070
Human
female gamete generation GO:0007292 2 0.069
Fly
regulation of cellular amine metabolic process GO:0033238 11 0.069
cellular amino acid metabolic process GO:0006520 116 0.068
positive regulation of phosphorylation GO:0042327 394 0.067
Human
nucleoside phosphate biosynthetic process GO:1901293 109 0.063
purine ribonucleoside metabolic process GO:0046128 437 0.063
post embryonic development GO:0009791 2 0.059
Worm
signal transduction by phosphorylation GO:0023014 297 0.055
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
positive regulation of cellular amine metabolic process GO:0033240 7 0.052
coenzyme a metabolic process GO:0015936 6 0.049
carbohydrate derivative biosynthetic process GO:1901137 207 0.048
nervous system development GO:0007399 293 0.044
Fly
determination of adult lifespan GO:0008340 2 0.044
Worm Fly
cellular lipid metabolic process GO:0044255 303 0.043
cytoplasmic transport GO:0016482 379 0.042
membrane organization GO:0061024 292 0.041
single organism membrane organization GO:0044802 268 0.041
negative regulation of catalytic activity GO:0043086 335 0.040
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
regulation of mapk cascade GO:0043408 262 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.036
regulation of protein kinase activity GO:0045859 289 0.035
ribonucleotide biosynthetic process GO:0009260 81 0.034
nucleoside triphosphate metabolic process GO:0009141 422 0.033
rna processing GO:0006396 255 0.033
single organism cellular localization GO:1902580 332 0.032
lipid metabolic process GO:0006629 381 0.032
Fly
regulation of kinase activity GO:0043549 314 0.032
cofactor biosynthetic process GO:0051188 31 0.032
regulation of transferase activity GO:0051338 355 0.030
defense response GO:0006952 315 0.029
vesicle mediated transport GO:0016192 371 0.029
Fly
covalent chromatin modification GO:0016569 254 0.029
Human
regulation of response to external stimulus GO:0032101 222 0.029
Worm Fly
mapk cascade GO:0000165 288 0.028
positive regulation of transferase activity GO:0051347 227 0.028
trna processing GO:0008033 23 0.027
nucleoside bisphosphate metabolic process GO:0033865 7 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
response to fungus GO:0009620 4 0.027
actin cytoskeleton organization GO:0030036 207 0.026
Fly
cellular macromolecular complex assembly GO:0034622 324 0.026
positive regulation of cell death GO:0010942 263 0.025
Human
glycosyl compound catabolic process GO:1901658 413 0.025
ncrna metabolic process GO:0034660 108 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
Worm Fly
protein catabolic process GO:0030163 325 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
Human
endomembrane system organization GO:0010256 196 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
cellular response to external stimulus GO:0071496 111 0.023
Worm Fly
axon cargo transport GO:0008088 2 0.023
ribonucleoside bisphosphate metabolic process GO:0033875 7 0.023
nucleotide biosynthetic process GO:0009165 109 0.023
multicellular organismal aging GO:0010259 3 0.022
Worm Fly
negative regulation of protein metabolic process GO:0051248 391 0.022
Human
positive regulation of protein kinase activity GO:0045860 190 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.022
Human
purine ribonucleotide catabolic process GO:0009154 404 0.021
macroautophagy GO:0016236 39 0.021
Worm Fly
positive regulation of programmed cell death GO:0043068 249 0.021
Human
ubiquitin dependent protein catabolic process GO:0006511 206 0.021
internal protein amino acid acetylation GO:0006475 101 0.021
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.021
Fly
cell development GO:0048468 328 0.021
Fly
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
Human
system process GO:0003008 349 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
cell cycle phase transition GO:0044770 173 0.020
Human
lipid biosynthetic process GO:0008610 177 0.020
positive regulation of cytoskeleton organization GO:0051495 83 0.020
cellular ketone metabolic process GO:0042180 80 0.020
regulation of cellular component biogenesis GO:0044087 281 0.019
Worm
response to other organism GO:0051707 261 0.019
positive regulation of mapk cascade GO:0043410 190 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
purine containing compound catabolic process GO:0072523 411 0.019
dephosphorylation GO:0016311 209 0.018
regulation of cell cycle GO:0051726 393 0.018
Human
positive regulation of kinase activity GO:0033674 204 0.018
chemical homeostasis GO:0048878 306 0.018
protein autophosphorylation GO:0046777 123 0.018
ras protein signal transduction GO:0007265 73 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
Human Worm
chromatin organization GO:0006325 351 0.018
Human
nitrogen compound transport GO:0071705 191 0.018
actin filament based process GO:0030029 224 0.018
Fly
negative regulation of cell proliferation GO:0008285 228 0.018
Human
cellular protein catabolic process GO:0044257 261 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
regulation of locomotion GO:0040012 329 0.017
regulation of cell motility GO:2000145 299 0.017
apoptotic signaling pathway GO:0097190 268 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
negative regulation of cell death GO:0060548 345 0.017
Human
negative regulation of programmed cell death GO:0043069 321 0.017
Human
ncrna processing GO:0034470 83 0.017
coenzyme metabolic process GO:0006732 65 0.017
biological adhesion GO:0022610 331 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
Human Fly
regeneration GO:0031099 4 0.017
mating GO:0007618 1 0.017
organophosphate catabolic process GO:0046434 430 0.017
regulation of cell cycle process GO:0010564 266 0.017
vesicle organization GO:0016050 62 0.017
regulation of protein localization GO:0032880 296 0.017
purine nucleotide catabolic process GO:0006195 405 0.017
regulation of cellular component movement GO:0051270 334 0.016
cell growth GO:0016049 160 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
ribonucleoside biosynthetic process GO:0042455 25 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
nucleotide catabolic process GO:0009166 408 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
negative regulation of organelle organization GO:0010639 126 0.016
spermatid development GO:0007286 4 0.016
protein ubiquitination GO:0016567 314 0.016
purine containing compound biosynthetic process GO:0072522 88 0.016
neuromuscular junction development GO:0007528 3 0.016
Fly
oocyte development GO:0048599 1 0.016
regulation of protein complex assembly GO:0043254 147 0.016
epithelium development GO:0060429 227 0.016
positive regulation of transport GO:0051050 336 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
plasma membrane organization GO:0007009 115 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
cellular response to abiotic stimulus GO:0071214 117 0.015
innate immune response GO:0045087 178 0.015
cell projection organization GO:0030030 252 0.015
Fly
ribose phosphate biosynthetic process GO:0046390 82 0.015
purine ribonucleotide biosynthetic process GO:0009152 79 0.015
secretion by cell GO:0032940 226 0.015
regulation of actin filament based process GO:0032970 141 0.015
cellular protein complex assembly GO:0043623 188 0.015
positive regulation of catabolic process GO:0009896 310 0.015
Worm Fly
rna splicing GO:0008380 131 0.014
behavior GO:0007610 112 0.014
Fly
nucleoside catabolic process GO:0009164 408 0.014
protein acylation GO:0043543 138 0.014
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
lipid localization GO:0010876 106 0.014
response to external biotic stimulus GO:0043207 261 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
oocyte differentiation GO:0009994 2 0.014
organelle assembly GO:0070925 176 0.014
Worm
regulation of intracellular transport GO:0032386 195 0.014
endocytosis GO:0006897 159 0.014
Fly
atp metabolic process GO:0046034 176 0.014
secretion GO:0046903 254 0.014
glycerolipid metabolic process GO:0046486 107 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
ribonucleoside catabolic process GO:0042454 406 0.014
negative regulation of cell cycle GO:0045786 193 0.014
Human
spermatid differentiation GO:0048515 4 0.014
purine nucleotide biosynthetic process GO:0006164 84 0.014
regulation of proteolysis GO:0030162 293 0.014
Human
regulation of map kinase activity GO:0043405 108 0.014
organelle fission GO:0048285 149 0.014
microtubule based process GO:0007017 210 0.014
peptidyl lysine acetylation GO:0018394 101 0.014
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.013
response to radiation GO:0009314 151 0.013
blastoderm segmentation GO:0007350 2 0.013
growth GO:0040007 202 0.013
Fly
response to abiotic stimulus GO:0009628 336 0.013
Worm
protein polyubiquitination GO:0000209 110 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
glycerolipid biosynthetic process GO:0045017 51 0.013
immune response GO:0006955 307 0.013
regulation of anatomical structure size GO:0090066 101 0.013
Fly
regulation of jnk cascade GO:0046328 73 0.013
carbohydrate metabolic process GO:0005975 207 0.013
regulation of dna metabolic process GO:0051052 153 0.013
nuclear division GO:0000280 128 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
positive regulation of immune response GO:0050778 159 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
regulation of cell migration GO:0030334 289 0.013
response to biotic stimulus GO:0009607 276 0.013
response to oxygen containing compound GO:1901700 369 0.013
Human
regulation of transporter activity GO:0032409 82 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
defense response to fungus GO:0050832 4 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
Human
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.013
cytokine production GO:0001816 247 0.013
mitotic cell cycle process GO:1903047 286 0.012
Human
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.012
transmembrane transport GO:0055085 399 0.012
apoptotic mitochondrial changes GO:0008637 57 0.012
chromatin modification GO:0016568 298 0.012
Human
neurogenesis GO:0022008 169 0.012
Fly
actin filament organization GO:0007015 128 0.012
Fly
cell projection morphogenesis GO:0048858 129 0.012
Fly
stress activated mapk cascade GO:0051403 93 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
golgi vesicle transport GO:0048193 80 0.012
gtp metabolic process GO:0046039 239 0.012
establishment of protein localization to plasma membrane GO:0090002 68 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
multi organism cellular process GO:0044764 156 0.012
rna interference GO:0016246 4 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.012
phospholipid metabolic process GO:0006644 99 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
protein secretion GO:0009306 98 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
chromosome segregation GO:0007059 114 0.011
locomotory behavior GO:0007626 1 0.011
regulation of cell differentiation GO:0045595 393 0.011
gtp catabolic process GO:0006184 237 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
Worm Fly
peptidyl serine modification GO:0018209 106 0.011
Human
segmentation GO:0035282 4 0.011
compound eye development GO:0048749 1 0.011
epithelial cell migration GO:0010631 119 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
trna modification GO:0006400 10 0.011
meiotic chromosome segregation GO:0045132 4 0.011
regulation of protein transport GO:0051223 213 0.011
positive regulation of organelle organization GO:0010638 195 0.011
Human Worm
viral life cycle GO:0019058 132 0.011
regulation of phosphatase activity GO:0010921 81 0.011
jnk cascade GO:0007254 80 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
Human
positive regulation of cell motility GO:2000147 177 0.011
endosomal transport GO:0016197 129 0.011
purine ribonucleoside catabolic process GO:0046130 398 0.011
microtubule based movement GO:0007018 32 0.011
nuclear transport GO:0051169 179 0.011
activation of immune response GO:0002253 114 0.011
mitochondrion organization GO:0007005 156 0.011
regulation of stress activated mapk cascade GO:0032872 84 0.011
mitotic cell cycle GO:0000278 326 0.011
Human
guanosine containing compound catabolic process GO:1901069 239 0.011
multicellular organismal response to stress GO:0033555 1 0.011
trna metabolic process GO:0006399 35 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
protein oligomerization GO:0051259 173 0.011
protein localization to membrane GO:0072657 160 0.010
regulation of protein serine threonine kinase activity GO:0071900 179 0.010
negative regulation of transport GO:0051051 176 0.010
positive regulation of cell size GO:0045793 3 0.010
Fly
response to light stimulus GO:0009416 87 0.010
atp catabolic process GO:0006200 157 0.010
mitotic nuclear division GO:0007067 119 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.010
Human
central nervous system development GO:0007417 123 0.010
regulation of secretion by cell GO:1903530 177 0.010
reproduction GO:0000003 63 0.010
Worm Fly
immune response regulating signaling pathway GO:0002764 97 0.010

RPS6KB2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.021
musculoskeletal system disease DOID:17 223 0.017
cancer DOID:162 167 0.014
organ system cancer DOID:0050686 164 0.012
sensory system disease DOID:0050155 203 0.012
eye and adnexa disease DOID:1492 150 0.012
nervous system disease DOID:863 431 0.012
eye disease DOID:5614 149 0.012
central nervous system disease DOID:331 186 0.010
brain disease DOID:936 73 0.010