Homo sapiens

24 known processes

ATXN2L

ataxin 2-like

(Aliases: A2LP,A2D,A2LG,A2RP)

ATXN2L biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell differentiation GO:0045595 393 0.194
post embryonic development GO:0009791 2 0.185
cellular macromolecule catabolic process GO:0044265 380 0.102
nervous system development GO:0007399 293 0.087
covalent chromatin modification GO:0016569 254 0.082
regulation of cell cycle process GO:0010564 266 0.068
chromatin modification GO:0016568 298 0.068
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.067
determination of adult lifespan GO:0008340 2 0.059
multicellular organismal aging GO:0010259 3 0.058
regulation of cell development GO:0060284 161 0.057
small gtpase mediated signal transduction GO:0007264 78 0.052
somatic stem cell division GO:0048103 1 0.051
histone modification GO:0016570 251 0.051
cell development GO:0048468 328 0.049
locomotory behavior GO:0007626 1 0.044
regulation of cell cycle GO:0051726 393 0.044
neurogenesis GO:0022008 169 0.044
ras protein signal transduction GO:0007265 73 0.044
cell fate determination GO:0001709 3 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.041
dephosphorylation GO:0016311 209 0.041
female gamete generation GO:0007292 2 0.041
posttranscriptional regulation of gene expression GO:0010608 213 0.040
mitotic cell cycle process GO:1903047 286 0.039
wnt signaling pathway GO:0016055 156 0.039
actin cytoskeleton organization GO:0030036 207 0.038
chromatin organization GO:0006325 351 0.038
cell morphogenesis GO:0000902 296 0.037
cell projection organization GO:0030030 252 0.037
protein catabolic process GO:0030163 325 0.036
negative regulation of cellular component organization GO:0051129 235 0.036
negative regulation of developmental process GO:0051093 247 0.036
mitotic cell cycle GO:0000278 326 0.035
positive regulation of catabolic process GO:0009896 310 0.035
rna processing GO:0006396 255 0.035
cellular component morphogenesis GO:0032989 314 0.034
neuron differentiation GO:0030182 138 0.034
neuroblast division GO:0055057 1 0.033
neuromuscular junction development GO:0007528 3 0.033
mapk cascade GO:0000165 288 0.033
morphogenesis of embryonic epithelium GO:0016331 4 0.032
ubiquitin dependent protein catabolic process GO:0006511 206 0.032
segmentation GO:0035282 4 0.032
regulation of cellular response to stress GO:0080135 244 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.032
vesicle mediated transport GO:0016192 371 0.031
modification dependent protein catabolic process GO:0019941 209 0.031
regulation of cell division GO:0051302 116 0.031
signal transduction by phosphorylation GO:0023014 297 0.031
proteasomal protein catabolic process GO:0010498 176 0.030
nucleotide catabolic process GO:0009166 408 0.030
mrna metabolic process GO:0016071 175 0.030
stem cell division GO:0017145 2 0.030
negative regulation of cell proliferation GO:0008285 228 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
regulation of nervous system development GO:0051960 88 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
biological adhesion GO:0022610 331 0.030
actin filament based process GO:0030029 224 0.029
modification dependent macromolecule catabolic process GO:0043632 212 0.029
protein modification by small protein conjugation GO:0032446 342 0.029
response to oxygen containing compound GO:1901700 369 0.029
rho protein signal transduction GO:0007266 26 0.029
regulation of protein catabolic process GO:0042176 155 0.028
regulation of proteolysis GO:0030162 293 0.028
mitotic cell cycle phase transition GO:0044772 162 0.028
cellular protein catabolic process GO:0044257 261 0.028
protein ubiquitination GO:0016567 314 0.028
anterior posterior axis specification GO:0009948 2 0.027
generation of neurons GO:0048699 152 0.027
negative regulation of multicellular organismal process GO:0051241 317 0.027
regulation of mitotic cell cycle GO:0007346 189 0.027
organelle assembly GO:0070925 176 0.027
embryo development GO:0009790 123 0.027
negative regulation of protein metabolic process GO:0051248 391 0.026
circadian behavior GO:0048512 2 0.026
negative regulation of cell cycle GO:0045786 193 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
cellular macromolecular complex assembly GO:0034622 324 0.026
oogenesis GO:0048477 2 0.026
intracellular protein transport GO:0006886 270 0.026
muscle structure development GO:0061061 98 0.025
regulation of ras protein signal transduction GO:0046578 155 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
taxis GO:0042330 157 0.024
positive regulation of developmental process GO:0051094 314 0.024
somatic stem cell maintenance GO:0035019 4 0.024
neuroblast proliferation GO:0007405 4 0.024
neuronal stem cell division GO:0036445 1 0.024
regulation of cell cycle phase transition GO:1901987 126 0.024
regulation of protein localization GO:0032880 296 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.023
associative learning GO:0008306 1 0.023
rhythmic behavior GO:0007622 2 0.023
regulation of small gtpase mediated signal transduction GO:0051056 156 0.023
cytoplasmic transport GO:0016482 379 0.023
positive regulation of cell cycle GO:0045787 140 0.023
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
positive regulation of programmed cell death GO:0043068 249 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
cell cycle phase transition GO:0044770 173 0.022
asymmetric neuroblast division GO:0055059 1 0.022
growth GO:0040007 202 0.021
amine metabolic process GO:0009308 44 0.021
ribonucleotide catabolic process GO:0009261 405 0.021
protein localization to organelle GO:0033365 280 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
regulation of establishment of protein localization GO:0070201 242 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
internal protein amino acid acetylation GO:0006475 101 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.020
histone acetylation GO:0016573 93 0.020
regulation of cytokine production GO:0001817 232 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
compound eye development GO:0048749 1 0.020
response to abiotic stimulus GO:0009628 336 0.020
behavior GO:0007610 112 0.020
regulation of cell migration GO:0030334 289 0.020
adult locomotory behavior GO:0008344 1 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.020
cell morphogenesis involved in differentiation GO:0000904 144 0.020
cell division GO:0051301 168 0.019
spermatid differentiation GO:0048515 4 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
maintenance of location GO:0051235 112 0.019
asymmetric stem cell division GO:0098722 1 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
embryonic epithelial tube formation GO:0001838 4 0.019
cell adhesion GO:0007155 325 0.019
response to cytokine GO:0034097 232 0.019
positive regulation of cell differentiation GO:0045597 211 0.019
cytokine production GO:0001816 247 0.019
response to lipid GO:0033993 206 0.019
blastoderm segmentation GO:0007350 2 0.019
photoreceptor cell differentiation GO:0046530 2 0.019
negative regulation of cell differentiation GO:0045596 171 0.019
response to external biotic stimulus GO:0043207 261 0.019
regeneration GO:0031099 4 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.018
negative regulation of cell death GO:0060548 345 0.018
regulation of transferase activity GO:0051338 355 0.018
metencephalon development GO:0022037 2 0.018
protein acylation GO:0043543 138 0.018
regulation of mapk cascade GO:0043408 262 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
regulation of gene expression epigenetic GO:0040029 73 0.018
immune response GO:0006955 307 0.018
stem cell differentiation GO:0048863 93 0.018
neuron development GO:0048666 113 0.018
epithelium development GO:0060429 227 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
i kappab kinase nf kappab signaling GO:0007249 166 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
regulation of cell motility GO:2000145 299 0.017
single organism reproductive process GO:0044702 98 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
purine nucleoside triphosphate catabolic process GO:0009146 392 0.017
regulation of cellular protein catabolic process GO:1903362 96 0.017
negative regulation of mitotic cell cycle GO:0045930 102 0.017
system process GO:0003008 349 0.017
spermatid development GO:0007286 4 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
regulation of mitotic cell cycle phase transition GO:1901990 118 0.017
mitochondrion organization GO:0007005 156 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
endochondral bone morphogenesis GO:0060350 3 0.017
negative regulation of proteolysis GO:0045861 132 0.017
peptidyl lysine modification GO:0018205 144 0.017
histone methylation GO:0016571 60 0.017
lipid metabolic process GO:0006629 381 0.017
cell part morphogenesis GO:0032990 137 0.017
central nervous system development GO:0007417 123 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
embryonic placenta development GO:0001892 1 0.017
nitrogen compound transport GO:0071705 191 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
methylation GO:0032259 106 0.017
organ formation GO:0048645 3 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
syncytium formation by plasma membrane fusion GO:0000768 2 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
protein maturation GO:0051604 233 0.016
cell growth GO:0016049 160 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
single organism membrane organization GO:0044802 268 0.016
memory GO:0007613 3 0.016
neural tube formation GO:0001841 3 0.016
cardiovascular system development GO:0072358 262 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
regulation of gtpase activity GO:0043087 180 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
regulation of cell projection organization GO:0031344 107 0.016
chemotaxis GO:0006935 157 0.016
immune system development GO:0002520 195 0.015
protein autophosphorylation GO:0046777 123 0.015
hemopoiesis GO:0030097 180 0.015
multi organism cellular process GO:0044764 156 0.015
cellular response to cytokine stimulus GO:0071345 181 0.015
protein targeting GO:0006605 187 0.015
regulation of growth GO:0040008 165 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
regulation of proteasomal protein catabolic process GO:0061136 87 0.015
dna repair GO:0006281 198 0.015
limbic system development GO:0021761 3 0.015
organophosphate catabolic process GO:0046434 430 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
regulation of meiotic cell cycle GO:0051445 4 0.015
hindbrain development GO:0030902 3 0.015
negative regulation of protein maturation GO:1903318 142 0.015
regulation of ras gtpase activity GO:0032318 128 0.015
myoblast fusion GO:0007520 1 0.015
positive regulation of protein kinase activity GO:0045860 190 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
response to organonitrogen compound GO:0010243 156 0.015
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
lipid localization GO:0010876 106 0.014
apoptotic signaling pathway GO:0097190 268 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
trophectodermal cell differentiation GO:0001829 3 0.014
regulation of neuroblast proliferation GO:1902692 3 0.014
protein oligomerization GO:0051259 173 0.014
response to biotic stimulus GO:0009607 276 0.014
neuron projection development GO:0031175 106 0.014
positive regulation of cell cycle process GO:0090068 106 0.014
cell activation GO:0001775 213 0.014
negative regulation of wnt signaling pathway GO:0030178 69 0.014
protein methylation GO:0006479 74 0.014
regulation of protein kinase activity GO:0045859 289 0.014
secretion GO:0046903 254 0.014
cell cycle checkpoint GO:0000075 117 0.014
regulation of protein maturation GO:1903317 150 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
mitotic nuclear division GO:0007067 119 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
ossification GO:0001503 121 0.014
t cell differentiation in thymus GO:0033077 4 0.014
negative regulation of protein processing GO:0010955 142 0.014
reproductive process GO:0022414 106 0.014
rna interference GO:0016246 4 0.014
rna splicing GO:0008380 131 0.014
regulation of secretion GO:0051046 194 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
positive regulation of gtpase activity GO:0043547 166 0.014
interspecies interaction between organisms GO:0044419 156 0.014
histone lysine methylation GO:0034968 50 0.014
microtubule based process GO:0007017 210 0.014
primary neural tube formation GO:0014020 3 0.014
regulation of kinase activity GO:0043549 314 0.014
mrna catabolic process GO:0006402 56 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
endocytosis GO:0006897 159 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
cation transport GO:0006812 331 0.013
blastocyst formation GO:0001825 3 0.013
neurological system process GO:0050877 163 0.013
mrna processing GO:0006397 133 0.013
regulation of dephosphorylation GO:0035303 96 0.013
regulation of meiosis GO:0040020 3 0.013
developmental process involved in reproduction GO:0003006 66 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.013
positive regulation of cell death GO:0010942 263 0.013
cellular ketone metabolic process GO:0042180 80 0.013
protein processing GO:0016485 226 0.013
lung alveolus development GO:0048286 4 0.013
regulation of canonical wnt signaling pathway GO:0060828 88 0.013
negative regulation of transport GO:0051051 176 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
protein localization to nucleus GO:0034504 136 0.013
regulation of nuclear division GO:0051783 65 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.013
cell projection morphogenesis GO:0048858 129 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
cellular amino acid metabolic process GO:0006520 116 0.013
receptor metabolic process GO:0043112 81 0.013
head development GO:0060322 108 0.013
peripheral nervous system development GO:0007422 2 0.013
negative regulation of catabolic process GO:0009895 104 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
regulation of phosphatase activity GO:0010921 81 0.013
regulation of response to external stimulus GO:0032101 222 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
cellular homeostasis GO:0019725 196 0.013
embryonic morphogenesis GO:0048598 85 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
neural tube closure GO:0001843 3 0.013
cellular lipid metabolic process GO:0044255 303 0.013
macromolecule methylation GO:0043414 97 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
protein dephosphorylation GO:0006470 81 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
regulation of mitosis GO:0007088 63 0.013
single organism cellular localization GO:1902580 332 0.013
lipid biosynthetic process GO:0008610 177 0.013
tissue regeneration GO:0042246 3 0.012
peptidyl lysine acetylation GO:0018394 101 0.012
anion transport GO:0006820 161 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
nucleoside triphosphate catabolic process GO:0009143 394 0.012
negative regulation of cell cycle phase transition GO:1901988 89 0.012
somitogenesis GO:0001756 2 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
leukocyte activation GO:0045321 164 0.012
brain development GO:0007420 97 0.012
regulation of stem cell differentiation GO:2000736 56 0.012
regulation of neurogenesis GO:0050767 82 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
tripartite regional subdivision GO:0007351 2 0.012
regulation of dna metabolic process GO:0051052 153 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
positive regulation of ras gtpase activity GO:0032320 117 0.012
regulation of chromosome organization GO:0033044 103 0.012
tube development GO:0035295 125 0.012
chromosome segregation GO:0007059 114 0.012
endomembrane system organization GO:0010256 196 0.012
cell cycle g2 m phase transition GO:0044839 43 0.012
membrane organization GO:0061024 292 0.012
chemical homeostasis GO:0048878 306 0.012
regulation of protein stability GO:0031647 87 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
response to other organism GO:0051707 261 0.012
myosin filament assembly GO:0031034 2 0.012
regulation of rho gtpase activity GO:0032319 66 0.012
sister chromatid segregation GO:0000819 54 0.012
organelle fission GO:0048285 149 0.012
muscle cell differentiation GO:0042692 63 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
rna catabolic process GO:0006401 71 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
negative regulation of organelle organization GO:0010639 126 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
myeloid cell differentiation GO:0030099 117 0.012
cellular chemical homeostasis GO:0055082 180 0.012
regulation of cellular component movement GO:0051270 334 0.012
positive regulation of immune system process GO:0002684 283 0.012
skeletal system development GO:0001501 79 0.012
positive regulation of transferase activity GO:0051347 227 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
regulation of rho protein signal transduction GO:0035023 79 0.012
regulation of neuron differentiation GO:0045664 70 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.011
regulation of neuron projection development GO:0010975 57 0.011
translation GO:0006412 132 0.011
oocyte development GO:0048599 1 0.011
cytokine mediated signaling pathway GO:0019221 109 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
g2 m transition of mitotic cell cycle GO:0000086 41 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
purine containing compound catabolic process GO:0072523 411 0.011
circulatory system development GO:0072359 262 0.011
cellular amine metabolic process GO:0044106 41 0.011
cellular protein complex assembly GO:0043623 188 0.011
regulation of intracellular transport GO:0032386 195 0.011
protein acetylation GO:0006473 116 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
carbohydrate metabolic process GO:0005975 207 0.011
regulation of stress activated mapk cascade GO:0032872 84 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
cytokinesis GO:0000910 96 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
stress activated mapk cascade GO:0051403 93 0.011
oocyte differentiation GO:0009994 2 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
regulation of protein transport GO:0051223 213 0.011
osteoblast differentiation GO:0001649 92 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
nuclear division GO:0000280 128 0.011
protein stabilization GO:0050821 64 0.011
nucleoside catabolic process GO:0009164 408 0.011
regulation of locomotion GO:0040012 329 0.011
tube closure GO:0060606 3 0.011
ncrna metabolic process GO:0034660 108 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
positive regulation of stress activated mapk cascade GO:0032874 60 0.010
cation transmembrane transport GO:0098655 238 0.010
nuclear transport GO:0051169 179 0.010
canonical wnt signaling pathway GO:0060070 116 0.010
positive regulation of mitotic cell cycle GO:0045931 60 0.010
reproduction GO:0000003 63 0.010
nuclear migration GO:0007097 1 0.010
cerebellum development GO:0021549 2 0.010
positive regulation of kinase activity GO:0033674 204 0.010
negative regulation of cell development GO:0010721 48 0.010
neural crest cell development GO:0014032 3 0.010
striated muscle myosin thick filament assembly GO:0071688 2 0.010
protein alkylation GO:0008213 74 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
innate immune response GO:0045087 178 0.010
morphogenesis of a polarized epithelium GO:0001738 3 0.010
protein localization to membrane GO:0072657 160 0.010
response to hormone GO:0009725 175 0.010

ATXN2L disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.037
disease of cellular proliferation DOID:14566 174 0.037
central nervous system disease DOID:331 186 0.031
neurodegenerative disease DOID:1289 102 0.031
nervous system disease DOID:863 431 0.031
musculoskeletal system disease DOID:17 223 0.025
sensory system disease DOID:0050155 203 0.022
organ system cancer DOID:0050686 164 0.021
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.018
spinocerebellar degeneration DOID:2478 27 0.017
disease of metabolism DOID:0014667 295 0.013
immune system disease DOID:2914 155 0.012