Homo sapiens

2 known processes

PCBD1

pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha

(Aliases: PHS,PCBD,DCOH,PCD)

PCBD1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid biosynthetic process GO:0016053 97 0.315
cellular amino acid metabolic process GO:0006520 116 0.175
cellular lipid metabolic process GO:0044255 303 0.136
lipid metabolic process GO:0006629 381 0.127
purine ribonucleotide catabolic process GO:0009154 404 0.122
organophosphate catabolic process GO:0046434 430 0.120
nucleoside phosphate catabolic process GO:1901292 412 0.116
purine ribonucleoside metabolic process GO:0046128 437 0.112
protein homotetramerization GO:0051289 28 0.111
carboxylic acid biosynthetic process GO:0046394 97 0.109
nucleoside monophosphate metabolic process GO:0009123 191 0.108
secretion GO:0046903 254 0.108
cellular amine metabolic process GO:0044106 41 0.108
oxidation reduction process GO:0055114 396 0.107
monocarboxylic acid metabolic process GO:0032787 185 0.105
small molecule biosynthetic process GO:0044283 157 0.104
locomotory behavior GO:0007626 1 0.100
organic hydroxy compound metabolic process GO:1901615 147 0.088
regulation of kidney size GO:0035564 2 0.085
response to oxygen containing compound GO:1901700 369 0.085
protein oligomerization GO:0051259 173 0.084
blastocyst development GO:0001824 3 0.083
organonitrogen compound biosynthetic process GO:1901566 200 0.080
ribonucleoside monophosphate metabolic process GO:0009161 187 0.079
protein homooligomerization GO:0051260 100 0.078
oogenesis GO:0048477 2 0.066
purine nucleoside monophosphate metabolic process GO:0009126 186 0.065
transmembrane transport GO:0055085 399 0.058
regulation of transferase activity GO:0051338 355 0.058
lipid localization GO:0010876 106 0.058
negative regulation of protein metabolic process GO:0051248 391 0.057
secretion by cell GO:0032940 226 0.056
cell projection organization GO:0030030 252 0.056
endodermal cell fate commitment GO:0001711 4 0.055
cofactor metabolic process GO:0051186 87 0.054
sulfur compound metabolic process GO:0006790 101 0.054
tetrapyrrole biosynthetic process GO:0033014 7 0.053
protein tetramerization GO:0051262 47 0.053
nucleotide catabolic process GO:0009166 408 0.052
steroid metabolic process GO:0008202 94 0.048
purine nucleotide catabolic process GO:0006195 405 0.047
organic hydroxy compound biosynthetic process GO:1901617 71 0.047
positive regulation of cellular amine metabolic process GO:0033240 7 0.046
determination of adult lifespan GO:0008340 2 0.045
monocarboxylic acid biosynthetic process GO:0072330 67 0.045
somatic stem cell maintenance GO:0035019 4 0.044
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.044
alcohol metabolic process GO:0006066 114 0.042
fatty acid biosynthetic process GO:0006633 46 0.042
anion transport GO:0006820 161 0.041
regulation of cellular amine metabolic process GO:0033238 11 0.041
female gamete generation GO:0007292 2 0.040
ribonucleotide catabolic process GO:0009261 405 0.040
regulation of hormone secretion GO:0046883 57 0.040
carbohydrate metabolic process GO:0005975 207 0.039
purine containing compound catabolic process GO:0072523 411 0.039
formation of primary germ layer GO:0001704 42 0.039
bile acid metabolic process GO:0008206 14 0.039
response to hormone GO:0009725 175 0.038
sterol metabolic process GO:0016125 28 0.038
spermatid development GO:0007286 4 0.038
system process GO:0003008 349 0.037
nucleoside monophosphate catabolic process GO:0009125 159 0.037
organic anion transport GO:0015711 103 0.036
pigment biosynthetic process GO:0046148 10 0.035
steroid biosynthetic process GO:0006694 46 0.035
positive regulation of cellular component organization GO:0051130 376 0.035
glycosyl compound catabolic process GO:1901658 413 0.035
regulation of protein kinase activity GO:0045859 289 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.034
amide transport GO:0042886 76 0.033
amine metabolic process GO:0009308 44 0.033
negative regulation of cellular protein metabolic process GO:0032269 353 0.033
mitochondrial transport GO:0006839 60 0.033
specification of organ identity GO:0010092 3 0.033
response to oxidative stress GO:0006979 121 0.033
intracellular protein transport GO:0006886 270 0.032
cytoplasmic transport GO:0016482 379 0.031
epithelium development GO:0060429 227 0.031
nucleoside triphosphate metabolic process GO:0009141 422 0.031
negative regulation of multicellular organismal process GO:0051241 317 0.031
organophosphate biosynthetic process GO:0090407 163 0.031
single organism cellular localization GO:1902580 332 0.031
response to abiotic stimulus GO:0009628 336 0.031
ras protein signal transduction GO:0007265 73 0.031
lipid biosynthetic process GO:0008610 177 0.030
regulation of heart morphogenesis GO:2000826 4 0.030
organic acid transport GO:0015849 65 0.030
cell morphogenesis GO:0000902 296 0.030
membrane organization GO:0061024 292 0.030
response to lipid GO:0033993 206 0.029
cellular response to oxygen containing compound GO:1901701 276 0.029
multicellular organismal aging GO:0010259 3 0.029
negative regulation of apoptotic process GO:0043066 316 0.029
small molecule catabolic process GO:0044282 92 0.029
positive regulation of apoptotic process GO:0043065 246 0.029
nitrogen compound transport GO:0071705 191 0.028
memory GO:0007613 3 0.028
cellular modified amino acid metabolic process GO:0006575 64 0.028
protein localization to organelle GO:0033365 280 0.028
endodermal cell fate specification GO:0001714 4 0.027
negative regulation of cell death GO:0060548 345 0.027
post embryonic development GO:0009791 2 0.027
establishment of protein localization to organelle GO:0072594 172 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
maintenance of location GO:0051235 112 0.026
purine nucleoside catabolic process GO:0006152 398 0.026
purine ribonucleoside catabolic process GO:0046130 398 0.026
cofactor biosynthetic process GO:0051188 31 0.026
regulation of proteolysis GO:0030162 293 0.025
reproductive process GO:0022414 106 0.025
organ induction GO:0001759 4 0.025
single organism membrane organization GO:0044802 268 0.025
establishment of protein localization to membrane GO:0090150 121 0.025
cardiac muscle cell contraction GO:0086003 4 0.025
regulation of purine nucleotide catabolic process GO:0033121 205 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
positive regulation of programmed cell death GO:0043068 249 0.024
regulation of kinase activity GO:0043549 314 0.024
regulation of protein complex assembly GO:0043254 147 0.024
nervous system development GO:0007399 293 0.024
alpha amino acid metabolic process GO:1901605 72 0.024
regulation of insulin secretion GO:0050796 33 0.023
mitochondrion organization GO:0007005 156 0.023
heart field specification GO:0003128 2 0.023
chemical homeostasis GO:0048878 306 0.023
regulation of secretion by cell GO:1903530 177 0.023
peptide transport GO:0015833 74 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
protein localization to membrane GO:0072657 160 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
cellular component morphogenesis GO:0032989 314 0.023
ribonucleoside catabolic process GO:0042454 406 0.022
lipid transport GO:0006869 90 0.022
small gtpase mediated signal transduction GO:0007264 78 0.022
cardiac cell fate specification GO:0060912 1 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
response to nitrogen compound GO:1901698 184 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
cellular response to organonitrogen compound GO:0071417 124 0.021
sterol transport GO:0015918 39 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
carboxylic acid transport GO:0046942 63 0.020
regulation of organ formation GO:0003156 4 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
response to organonitrogen compound GO:0010243 156 0.020
multicellular organismal homeostasis GO:0048871 67 0.020
negative regulation of developmental process GO:0051093 247 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
oocyte differentiation GO:0009994 2 0.020
regulation of secretion GO:0051046 194 0.020
protein targeting GO:0006605 187 0.020
cell cell signaling GO:0007267 155 0.019
innate immune response GO:0045087 178 0.019
negative regulation of protein modification process GO:0031400 200 0.019
spermatid differentiation GO:0048515 4 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
cellular amino acid biosynthetic process GO:0008652 30 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
cellular protein complex assembly GO:0043623 188 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
protein catabolic process GO:0030163 325 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
hindbrain development GO:0030902 3 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.018
directional locomotion GO:0033058 1 0.018
positive regulation of cell death GO:0010942 263 0.018
pronephros morphogenesis GO:0072114 1 0.018
cellular amide metabolic process GO:0043603 69 0.018
negative regulation of growth GO:0045926 97 0.018
purine ribonucleoside biosynthetic process GO:0046129 23 0.018
protein secretion GO:0009306 98 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
neuromuscular junction development GO:0007528 3 0.018
negative regulation of cell fate commitment GO:0010454 3 0.018
positive regulation of immune system process GO:0002684 283 0.018
actin filament based process GO:0030029 224 0.018
oocyte development GO:0048599 1 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
response to other organism GO:0051707 261 0.018
hormone secretion GO:0046879 65 0.017
regulation of transmembrane transport GO:0034762 139 0.017
organic acid catabolic process GO:0016054 71 0.017
regulation of cardioblast differentiation GO:0051890 4 0.017
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.017
plasma membrane organization GO:0007009 115 0.017
neurological system process GO:0050877 163 0.017
single organism reproductive process GO:0044702 98 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
regulation of hormone levels GO:0010817 125 0.017
epithelial cell differentiation GO:0030855 141 0.017
cellular ketone metabolic process GO:0042180 80 0.017
nucleotide biosynthetic process GO:0009165 109 0.017
regulation of ion transport GO:0043269 189 0.017
ion transmembrane transport GO:0034220 338 0.017
positive regulation of protein complex assembly GO:0031334 86 0.016
gastrulation GO:0007369 51 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
negative regulation of cell growth GO:0030308 83 0.016
adult locomotory behavior GO:0008344 1 0.016
positive regulation of cellular component biogenesis GO:0044089 158 0.016
regulation of heart induction GO:0090381 2 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
positive regulation of developmental process GO:0051094 314 0.016
positive regulation of transferase activity GO:0051347 227 0.016
coenzyme metabolic process GO:0006732 65 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
nucleoside phosphate biosynthetic process GO:1901293 109 0.016
metal ion transport GO:0030001 272 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
endocrine pancreas development GO:0031018 11 0.016
tetrapyrrole metabolic process GO:0033013 11 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
regulation of peptide transport GO:0090087 62 0.016
regulation of cytoplasmic transport GO:1903649 149 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
immune response GO:0006955 307 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
negative regulation of stem cell differentiation GO:2000737 22 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
regulation of cell cycle GO:0051726 393 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
inner ear morphogenesis GO:0042472 4 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
nucleoside catabolic process GO:0009164 408 0.015
renal absorption GO:0070293 6 0.015
protein maturation GO:0051604 233 0.015
central nervous system development GO:0007417 123 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
positive regulation of kinase activity GO:0033674 204 0.015
porphyrin containing compound metabolic process GO:0006778 10 0.015
microtubule based process GO:0007017 210 0.015
protein import GO:0017038 130 0.015
sulfur compound biosynthetic process GO:0044272 38 0.014
embryo development GO:0009790 123 0.014
nuclear transport GO:0051169 179 0.014
segmentation GO:0035282 4 0.014
lipid catabolic process GO:0016042 84 0.014
inorganic cation transmembrane transport GO:0098662 194 0.014
divalent metal ion transport GO:0070838 152 0.014
apoptotic signaling pathway GO:0097190 268 0.014
negative regulation of cell fate specification GO:0009996 3 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
regulation of wnt signaling pathway involved in heart development GO:0003307 3 0.014
response to external biotic stimulus GO:0043207 261 0.014
heart formation GO:0060914 2 0.014
regulation of protein maturation GO:1903317 150 0.014
axis elongation GO:0003401 4 0.014
organic hydroxy compound transport GO:0015850 63 0.014
ion homeostasis GO:0050801 230 0.014
pronephros development GO:0048793 2 0.013
lymphocyte activation GO:0046649 133 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
protein processing GO:0016485 226 0.013
regulation of intracellular transport GO:0032386 195 0.013
regulation of protein localization GO:0032880 296 0.013
response to axon injury GO:0048678 1 0.013
positive regulation of proteolysis GO:0045862 142 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
purine nucleoside monophosphate catabolic process GO:0009128 158 0.013
regulation of peptide hormone secretion GO:0090276 41 0.013
regulation of ion transmembrane transport GO:0034765 132 0.013
divalent inorganic cation transport GO:0072511 158 0.013
wnt signaling pathway GO:0016055 156 0.013
mating GO:0007618 1 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
rhythmic behavior GO:0007622 2 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
mesenchyme development GO:0060485 59 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.012
regulation of protein catabolic process GO:0042176 155 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
vesicle mediated transport GO:0016192 371 0.012
positive regulation of intracellular protein transport GO:0090316 76 0.012
dephosphorylation GO:0016311 209 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
regulation of gtpase activity GO:0043087 180 0.012
defense response GO:0006952 315 0.012
meiosis i GO:0007127 4 0.012
atp metabolic process GO:0046034 176 0.012
positive regulation of transport GO:0051050 336 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
fatty acid transport GO:0015908 25 0.012
leukocyte activation GO:0045321 164 0.012
regulation of cell growth GO:0001558 135 0.012
nucleobase biosynthetic process GO:0046112 4 0.012
cellular cation homeostasis GO:0030003 163 0.012
cellular ion homeostasis GO:0006873 168 0.012
regulation of protein stability GO:0031647 87 0.012
long term memory GO:0007616 2 0.011
tissue morphogenesis GO:0048729 96 0.011
cardioblast cell fate commitment GO:0042684 1 0.011
ribonucleoside monophosphate catabolic process GO:0009158 158 0.011
monosaccharide transport GO:0015749 32 0.011
negative regulation of protein processing GO:0010955 142 0.011
blastoderm segmentation GO:0007350 2 0.011
regulation of protein transport GO:0051223 213 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
associative learning GO:0008306 1 0.011
negative regulation of transport GO:0051051 176 0.011
mapk cascade GO:0000165 288 0.011
peptide metabolic process GO:0006518 51 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
response to bacterium GO:0009617 144 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
protein ubiquitination GO:0016567 314 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
cell activation GO:0001775 213 0.011
negative regulation of transferase activity GO:0051348 124 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
hemopoiesis GO:0030097 180 0.011
negative regulation of cardioblast differentiation GO:0051892 2 0.011
rho protein signal transduction GO:0007266 26 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
calcium ion transport GO:0006816 147 0.011
protein acetylation GO:0006473 116 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
cholesterol metabolic process GO:0008203 28 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
signal release GO:0023061 70 0.011
bile acid biosynthetic process GO:0006699 10 0.011
cation transport GO:0006812 331 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
porphyrin containing compound biosynthetic process GO:0006779 7 0.011
viral process GO:0016032 146 0.011
cell growth GO:0016049 160 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.010
cell development GO:0048468 328 0.010
digestive tract morphogenesis GO:0048546 56 0.010
negative regulation of cardioblast cell fate specification GO:0009997 1 0.010
fatty acid metabolic process GO:0006631 115 0.010
glutathione metabolic process GO:0006749 20 0.010
protein localization to mitochondrion GO:0070585 25 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.010
actin mediated cell contraction GO:0070252 12 0.010
pigment metabolic process GO:0042440 16 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
response to insulin GO:0032868 45 0.010
heme metabolic process GO:0042168 8 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
generation of neurons GO:0048699 152 0.010
peptide hormone secretion GO:0030072 50 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
mitotic cell cycle GO:0000278 326 0.010
carboxylic acid catabolic process GO:0046395 71 0.010
neuron differentiation GO:0030182 138 0.010
protein localization to plasma membrane GO:0072659 93 0.010

PCBD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.274
cancer DOID:162 167 0.178
disease of cellular proliferation DOID:14566 174 0.178
organ system cancer DOID:0050686 164 0.133
inherited metabolic disorder DOID:655 242 0.107
acquired metabolic disease DOID:0060158 58 0.053
kidney cancer DOID:263 11 0.039
urinary system cancer DOID:3996 15 0.039
nonpapillary renal cell carcinoma DOID:0050387 6 0.039
hereditary renal cell carcinoma DOID:4455 6 0.039
renal cell carcinoma DOID:4450 8 0.039
renal carcinoma DOID:4451 8 0.039
diabetes mellitus DOID:9351 31 0.030
carbohydrate metabolism disease DOID:0050013 32 0.030
glucose metabolism disease DOID:4194 32 0.030
central nervous system disease DOID:331 186 0.027
nervous system disease DOID:863 431 0.027
carbohydrate metabolic disorder DOID:2978 55 0.023
cardiovascular system disease DOID:1287 106 0.021
type 2 diabetes mellitus DOID:9352 28 0.020
maturity onset diabetes of the young DOID:0050524 10 0.019
immune system disease DOID:2914 155 0.017
myopathy DOID:423 104 0.016
muscular disease DOID:0080000 114 0.016
musculoskeletal system disease DOID:17 223 0.016
muscle tissue disease DOID:66 113 0.016
amino acid metabolic disorder DOID:9252 50 0.015
kidney disease DOID:557 36 0.012
urinary system disease DOID:18 40 0.012
neurodegenerative disease DOID:1289 102 0.012
gastrointestinal system cancer DOID:3119 52 0.011
sensory system disease DOID:0050155 203 0.011
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.011