Homo sapiens

154 known processes

PRDX3

peroxiredoxin 3

(Aliases: AOP-1,AOP1,SP-22,MER5,MGC24293,PRO1748,MGC104387)

PRDX3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.926
post embryonic development GO:0009791 2 0.380
multicellular organismal aging GO:0010259 3 0.364
determination of adult lifespan GO:0008340 2 0.355
cellular response to superoxide GO:0071451 6 0.259
Human
response to abiotic stimulus GO:0009628 336 0.255
monocarboxylic acid metabolic process GO:0032787 185 0.229
cellular homeostasis GO:0019725 196 0.197
purine ribonucleoside metabolic process GO:0046128 437 0.186
mitochondrion organization GO:0007005 156 0.171
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.158
protein processing GO:0016485 226 0.144
regulation of mitochondrial membrane potential GO:0051881 23 0.138
organophosphate catabolic process GO:0046434 430 0.126
cellular ketone metabolic process GO:0042180 80 0.124
cellular amino acid metabolic process GO:0006520 116 0.122
regulation of membrane potential GO:0042391 95 0.120
regulation of peptidase activity GO:0052547 180 0.117
purine nucleoside monophosphate metabolic process GO:0009126 186 0.094
fatty acid metabolic process GO:0006631 115 0.092
negative regulation of protein maturation GO:1903318 142 0.091
cellular response to oxygen radical GO:0071450 6 0.089
Human
lipid metabolic process GO:0006629 381 0.087
regulation of protein processing GO:0070613 150 0.084
regulation of cysteine type endopeptidase activity GO:2000116 127 0.082
energy derivation by oxidation of organic compounds GO:0015980 43 0.082
nucleoside triphosphate metabolic process GO:0009141 422 0.082
protein homooligomerization GO:0051260 100 0.075
cellular modified amino acid metabolic process GO:0006575 64 0.075
carboxylic acid biosynthetic process GO:0046394 97 0.070
defense response GO:0006952 315 0.070
hydrogen peroxide metabolic process GO:0042743 20 0.069
cellular lipid metabolic process GO:0044255 303 0.067
organic acid biosynthetic process GO:0016053 97 0.066
negative regulation of phosphorus metabolic process GO:0010563 267 0.065
purine nucleoside triphosphate catabolic process GO:0009146 392 0.065
regulation of multi organism process GO:0043900 157 0.060
small molecule biosynthetic process GO:0044283 157 0.060
regulation of cellular ketone metabolic process GO:0010565 50 0.060
spermatid differentiation GO:0048515 4 0.059
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.058
negative regulation of apoptotic process GO:0043066 316 0.058
reactive oxygen species metabolic process GO:0072593 75 0.058
negative regulation of peptidase activity GO:0010466 91 0.058
negative regulation of phosphate metabolic process GO:0045936 267 0.056
response to metal ion GO:0010038 84 0.056
negative regulation of multi organism process GO:0043901 92 0.055
cofactor metabolic process GO:0051186 87 0.055
cellular response to oxidative stress GO:0034599 85 0.054
purine ribonucleoside catabolic process GO:0046130 398 0.054
generation of precursor metabolites and energy GO:0006091 68 0.054
ribonucleoside monophosphate metabolic process GO:0009161 187 0.053
protein maturation GO:0051604 233 0.053
ribonucleoside triphosphate metabolic process GO:0009199 412 0.052
nucleoside catabolic process GO:0009164 408 0.052
nervous system development GO:0007399 293 0.051
purine nucleotide catabolic process GO:0006195 405 0.050
anatomical structure homeostasis GO:0060249 100 0.049
Human
protein oxidation GO:0018158 5 0.049
immune response GO:0006955 307 0.048
response to reactive oxygen species GO:0000302 61 0.047
hydrogen peroxide catabolic process GO:0042744 13 0.047
positive regulation of cellular amine metabolic process GO:0033240 7 0.047
cellular response to oxygen containing compound GO:1901701 276 0.046
negative regulation of cell proliferation GO:0008285 228 0.045
regulation of protein maturation GO:1903317 150 0.045
single organism reproductive process GO:0044702 98 0.044
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.044
lipid oxidation GO:0034440 33 0.044
proteasomal protein catabolic process GO:0010498 176 0.043
spermatid development GO:0007286 4 0.042
phototransduction GO:0007602 3 0.042
sulfur compound metabolic process GO:0006790 101 0.041
cellular amine metabolic process GO:0044106 41 0.041
positive regulation of cell proliferation GO:0008284 301 0.041
amine metabolic process GO:0009308 44 0.040
ribonucleotide catabolic process GO:0009261 405 0.040
negative regulation of cell death GO:0060548 345 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.039
response to oxidative stress GO:0006979 121 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.038
nucleoside monophosphate metabolic process GO:0009123 191 0.038
endomembrane system organization GO:0010256 196 0.038
response to wounding GO:0009611 168 0.037
glycosyl compound catabolic process GO:1901658 413 0.036
cellular response to reactive oxygen species GO:0034614 50 0.036
nucleotide catabolic process GO:0009166 408 0.036
negative regulation of catalytic activity GO:0043086 335 0.036
positive regulation of cytokine production GO:0001819 167 0.036
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.036
single organism cellular localization GO:1902580 332 0.036
cellular response to dna damage stimulus GO:0006974 379 0.035
lipid catabolic process GO:0016042 84 0.035
regulation of response to external stimulus GO:0032101 222 0.035
cellular macromolecule catabolic process GO:0044265 380 0.035
cellular response to hydrogen peroxide GO:0070301 37 0.034
multicellular organismal homeostasis GO:0048871 67 0.034
Human
female gamete generation GO:0007292 2 0.033
carbohydrate metabolic process GO:0005975 207 0.033
negative regulation of protein metabolic process GO:0051248 391 0.033
protein oligomerization GO:0051259 173 0.033
negative regulation of cellular protein metabolic process GO:0032269 353 0.033
response to oxygen containing compound GO:1901700 369 0.033
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.032
response to biotic stimulus GO:0009607 276 0.032
Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.031
positive regulation of hydrolase activity GO:0051345 331 0.031
single organism carbohydrate metabolic process GO:0044723 193 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.031
transmembrane transport GO:0055085 399 0.031
ras protein signal transduction GO:0007265 73 0.031
cellular component morphogenesis GO:0032989 314 0.031
carboxylic acid catabolic process GO:0046395 71 0.030
small molecule catabolic process GO:0044282 92 0.030
negative regulation of multicellular organismal process GO:0051241 317 0.030
secretion GO:0046903 254 0.030
regeneration GO:0031099 4 0.030
protein localization to organelle GO:0033365 280 0.029
multicellular organismal response to stress GO:0033555 1 0.029
cell development GO:0048468 328 0.029
response to external biotic stimulus GO:0043207 261 0.029
Mouse
purine nucleoside catabolic process GO:0006152 398 0.029
response to oxygen radical GO:0000305 6 0.029
Human
alpha amino acid metabolic process GO:1901605 72 0.029
regulation of cellular amine metabolic process GO:0033238 11 0.029
response to organic cyclic compound GO:0014070 204 0.029
negative regulation of proteolysis GO:0045861 132 0.028
guanosine containing compound metabolic process GO:1901068 244 0.028
negative regulation of phosphorylation GO:0042326 174 0.028
secretion by cell GO:0032940 226 0.027
positive regulation of programmed cell death GO:0043068 249 0.027
negative regulation of programmed cell death GO:0043069 321 0.027
dicarboxylic acid metabolic process GO:0043648 29 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.026
organophosphate biosynthetic process GO:0090407 163 0.026
peptidyl cysteine modification GO:0018198 9 0.026
positive regulation of apoptotic process GO:0043065 246 0.026
response to radiation GO:0009314 151 0.026
negative regulation of transferase activity GO:0051348 124 0.026
atp metabolic process GO:0046034 176 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
regulation of response to wounding GO:1903034 101 0.025
regulation of proteolysis GO:0030162 293 0.025
innate immune response GO:0045087 178 0.025
regulation of cytokine production GO:0001817 232 0.025
response to inorganic substance GO:0010035 127 0.024
signal transduction by phosphorylation GO:0023014 297 0.024
organic acid catabolic process GO:0016054 71 0.024
regulation of endopeptidase activity GO:0052548 170 0.024
cytokine production GO:0001816 247 0.024
alcohol metabolic process GO:0006066 114 0.024
positive regulation of catabolic process GO:0009896 310 0.024
regulation of kinase activity GO:0043549 314 0.023
rho protein signal transduction GO:0007266 26 0.023
inflammatory response GO:0006954 79 0.022
small gtpase mediated signal transduction GO:0007264 78 0.022
detection of stimulus GO:0051606 85 0.022
guanosine containing compound catabolic process GO:1901069 239 0.022
reproductive process GO:0022414 106 0.022
Mouse
negative regulation of kinase activity GO:0033673 106 0.022
cell projection organization GO:0030030 252 0.022
regulation of defense response GO:0031347 154 0.021
superoxide metabolic process GO:0006801 20 0.021
Human
cell morphogenesis GO:0000902 296 0.021
purine containing compound biosynthetic process GO:0072522 88 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
monocarboxylic acid biosynthetic process GO:0072330 67 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.021
defense response to other organism GO:0098542 129 0.021
response to hormone GO:0009725 175 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
ion transmembrane transport GO:0034220 338 0.020
wound healing GO:0042060 115 0.020
response to extracellular stimulus GO:0009991 85 0.020
fear response GO:0042596 0 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
purine containing compound catabolic process GO:0072523 411 0.018
system process GO:0003008 349 0.018
cellular respiration GO:0045333 21 0.018
microtubule based process GO:0007017 210 0.018
regulation of growth GO:0040008 165 0.018
positive regulation of transport GO:0051050 336 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
nucleotide biosynthetic process GO:0009165 109 0.018
positive regulation of immune response GO:0050778 159 0.018
segmentation GO:0035282 4 0.018
cell cell signaling GO:0007267 155 0.018
anterior posterior axis specification GO:0009948 2 0.017
lipid biosynthetic process GO:0008610 177 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
positive regulation of cell death GO:0010942 263 0.017
growth GO:0040007 202 0.017
chemical homeostasis GO:0048878 306 0.017
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.017
negative regulation of transport GO:0051051 176 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
regulation of transferase activity GO:0051338 355 0.017
anion transport GO:0006820 161 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
protein tetramerization GO:0051262 47 0.017
purine nucleotide biosynthetic process GO:0006164 84 0.017
cell projection morphogenesis GO:0048858 129 0.016
apoptotic mitochondrial changes GO:0008637 57 0.016
inorganic ion transmembrane transport GO:0098660 231 0.016
mitotic cell cycle process GO:1903047 286 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
response to virus GO:0009615 126 0.016
protein catabolic process GO:0030163 325 0.016
rna splicing GO:0008380 131 0.016
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.016
negative regulation of response to external stimulus GO:0032102 83 0.016
response to light stimulus GO:0009416 87 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
positive regulation of immune system process GO:0002684 283 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.015
amide transport GO:0042886 76 0.015
cell activation GO:0001775 213 0.015
membrane organization GO:0061024 292 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
epithelial cell differentiation GO:0030855 141 0.015
aging GO:0007568 66 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
negative regulation of protein processing GO:0010955 142 0.015
negative regulation of immune system process GO:0002683 136 0.015
organic hydroxy compound metabolic process GO:1901615 147 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
regulation of cellular response to stress GO:0080135 244 0.014
cation transport GO:0006812 331 0.014
cellular ion homeostasis GO:0006873 168 0.014
oogenesis GO:0048477 2 0.014
regulation of intracellular transport GO:0032386 195 0.014
i kappab kinase nf kappab signaling GO:0007249 166 0.014
reproductive system development GO:0061458 56 0.014
Mouse
rna processing GO:0006396 255 0.014
behavioral defense response GO:0002209 0 0.014
tissue regeneration GO:0042246 3 0.014
intracellular receptor signaling pathway GO:0030522 104 0.014
heat acclimation GO:0010286 3 0.014
reproduction GO:0000003 63 0.014
Mouse
regulation of protein localization GO:0032880 296 0.014
response to hydrogen peroxide GO:0042542 40 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
mapk cascade GO:0000165 288 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
lymphocyte activation GO:0046649 133 0.013
developmental process involved in reproduction GO:0003006 66 0.013
Mouse
regulation of mapk cascade GO:0043408 262 0.013
coenzyme metabolic process GO:0006732 65 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
regulation of response to biotic stimulus GO:0002831 55 0.013
apoptotic signaling pathway GO:0097190 268 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
mitotic cell cycle GO:0000278 326 0.013
leukocyte activation GO:0045321 164 0.013
protein acylation GO:0043543 138 0.013
positive regulation of defense response GO:0031349 87 0.013
protein acetylation GO:0006473 116 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
protein homotetramerization GO:0051289 28 0.012
circulatory system process GO:0003013 113 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
multicellular organism reproduction GO:0032504 42 0.012
Mouse
oocyte differentiation GO:0009994 2 0.012
activation of immune response GO:0002253 114 0.012
immune effector process GO:0002252 159 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
Mouse
response to temperature stimulus GO:0009266 22 0.012
reproductive structure development GO:0048608 55 0.012
Mouse
cytoplasmic transport GO:0016482 379 0.012
single organism membrane organization GO:0044802 268 0.012
blood circulation GO:0008015 113 0.012
embryo development GO:0009790 123 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
negative regulation of protein transport GO:0051224 75 0.012
cell part morphogenesis GO:0032990 137 0.012
hemopoiesis GO:0030097 180 0.012
Mouse
regulation of cell cycle process GO:0010564 266 0.012
regulation of secretion GO:0051046 194 0.012
protein targeting GO:0006605 187 0.012
regulation of protein kinase activity GO:0045859 289 0.012
blastoderm segmentation GO:0007350 2 0.012
adult locomotory behavior GO:0008344 1 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
response to nitrogen compound GO:1901698 184 0.012
epithelium development GO:0060429 227 0.011
ion homeostasis GO:0050801 230 0.011
tripartite regional subdivision GO:0007351 2 0.011
regulation of lipid metabolic process GO:0019216 96 0.011
calcium ion transport GO:0006816 147 0.011
mononuclear cell proliferation GO:0032943 71 0.011
metal ion transport GO:0030001 272 0.011
cellular carbohydrate metabolic process GO:0044262 84 0.011
neuromuscular junction development GO:0007528 3 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
gtp metabolic process GO:0046039 239 0.011
regulation of immune response GO:0050776 201 0.011
regulation of innate immune response GO:0045088 97 0.011
activation of protein kinase activity GO:0032147 90 0.011
cation transmembrane transport GO:0098655 238 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
cellular chemical homeostasis GO:0055082 180 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
negative regulation of protein modification process GO:0031400 200 0.011
locomotory behavior GO:0007626 1 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
response to lipid GO:0033993 206 0.011
Mouse
nucleoside monophosphate catabolic process GO:0009125 159 0.011
intracellular protein transport GO:0006886 270 0.011
response to molecule of bacterial origin GO:0002237 82 0.011
Mouse
lipid modification GO:0030258 84 0.011
response to other organism GO:0051707 261 0.011
Mouse
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
negative regulation of organelle organization GO:0010639 126 0.011
regulation of proteasomal protein catabolic process GO:0061136 87 0.011
regulation of cell differentiation GO:0045595 393 0.011
multi organism reproductive process GO:0044703 54 0.010
Mouse
response to nutrient levels GO:0031667 81 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
response to hypoxia GO:0001666 96 0.010
positive regulation of protein phosphorylation GO:0001934 313 0.010
generation of neurons GO:0048699 152 0.010
neural nucleus development GO:0048857 47 0.010
regulation of cell cycle GO:0051726 393 0.010
cell growth GO:0016049 160 0.010
behavioral fear response GO:0001662 0 0.010
endocytosis GO:0006897 159 0.010
male gamete generation GO:0048232 22 0.010
lymphocyte proliferation GO:0046651 70 0.010
ossification GO:0001503 121 0.010

PRDX3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.340
amino acid metabolic disorder DOID:9252 50 0.340
inherited metabolic disorder DOID:655 242 0.340
cancer DOID:162 167 0.034
disease of cellular proliferation DOID:14566 174 0.034
organ system cancer DOID:0050686 164 0.029
sensory system disease DOID:0050155 203 0.023
nervous system disease DOID:863 431 0.023
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.018
central nervous system disease DOID:331 186 0.014