Homo sapiens

9 known processes

PITX3

paired-like homeodomain 3

(Aliases: MGC12766,PTX3,CTPP4)

PITX3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of multicellular organismal process GO:0051241 317 0.304
system process GO:0003008 349 0.292
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.245
Human
cellular response to endogenous stimulus GO:0071495 336 0.244
epithelium development GO:0060429 227 0.233
Mouse
response to oxygen containing compound GO:1901700 369 0.232
negative regulation of developmental process GO:0051093 247 0.229
regulation of cellular ketone metabolic process GO:0010565 50 0.227
cellular amino acid metabolic process GO:0006520 116 0.214
neuron fate commitment GO:0048663 2 0.205
blood circulation GO:0008015 113 0.200
negative regulation of cell differentiation GO:0045596 171 0.198
anatomical structure formation involved in morphogenesis GO:0048646 284 0.190
cellular ketone metabolic process GO:0042180 80 0.179
organ morphogenesis GO:0009887 147 0.177
Human Mouse
cellular amine metabolic process GO:0044106 41 0.173
regulation of cell differentiation GO:0045595 393 0.166
transmembrane transport GO:0055085 399 0.163
circulatory system development GO:0072359 262 0.155
organ formation GO:0048645 3 0.153
positive regulation of cell proliferation GO:0008284 301 0.146
circulatory system process GO:0003013 113 0.140
cardiovascular system development GO:0072358 262 0.130
segmentation GO:0035282 4 0.124
epithelial cell differentiation GO:0030855 141 0.121
Mouse
cell fate determination GO:0001709 3 0.120
regulation of cellular amine metabolic process GO:0033238 11 0.118
cation transport GO:0006812 331 0.116
nervous system development GO:0007399 293 0.116
Zebrafish Mouse Worm Fly
cell development GO:0048468 328 0.115
Mouse Worm Fly
tube development GO:0035295 125 0.113
cellular metal ion homeostasis GO:0006875 146 0.109
positive regulation of cellular amine metabolic process GO:0033240 7 0.107
muscle structure development GO:0061061 98 0.105
post embryonic development GO:0009791 2 0.104
regulation of anatomical structure morphogenesis GO:0022603 286 0.101
cellular chemical homeostasis GO:0055082 180 0.098
hindbrain development GO:0030902 3 0.097
enzyme linked receptor protein signaling pathway GO:0007167 303 0.090
ion transmembrane transport GO:0034220 338 0.089
cellular response to oxygen containing compound GO:1901701 276 0.086
amine metabolic process GO:0009308 44 0.085
embryonic morphogenesis GO:0048598 85 0.085
cell cell signaling GO:0007267 155 0.083
regulation of cellular amino acid metabolic process GO:0006521 6 0.083
locomotory behavior GO:0007626 1 0.082
Mouse
cellular component morphogenesis GO:0032989 314 0.080
Worm Fly
response to growth factor GO:0070848 205 0.077
response to organic cyclic compound GO:0014070 204 0.077
regulation of system process GO:0044057 101 0.076
positive regulation of cellular component organization GO:0051130 376 0.074
neurological system process GO:0050877 163 0.073
forebrain generation of neurons GO:0021872 3 0.072
skeletal system development GO:0001501 79 0.071
Human
positive regulation of developmental process GO:0051094 314 0.070
hematopoietic or lymphoid organ development GO:0048534 186 0.070
secretion by cell GO:0032940 226 0.069
stem cell differentiation GO:0048863 93 0.069
cranial nerve development GO:0021545 4 0.069
ion homeostasis GO:0050801 230 0.069
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.067
cell projection organization GO:0030030 252 0.067
Worm Fly
cellular response to growth factor stimulus GO:0071363 197 0.066
cation homeostasis GO:0055080 189 0.065
metal ion homeostasis GO:0055065 169 0.064
negative regulation of catalytic activity GO:0043086 335 0.061
digestive system development GO:0055123 75 0.060
regulation of secretion by cell GO:1903530 177 0.060
positive regulation of phosphorylation GO:0042327 394 0.059
regulation of mapk cascade GO:0043408 262 0.058
cell differentiation in spinal cord GO:0021515 1 0.058
divalent inorganic cation homeostasis GO:0072507 136 0.056
generation of neurons GO:0048699 152 0.056
Mouse Worm Fly
muscle contraction GO:0006936 73 0.056
forebrain dorsal ventral pattern formation GO:0021798 1 0.056
negative regulation of phosphorus metabolic process GO:0010563 267 0.056
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.055
central nervous system development GO:0007417 123 0.054
Zebrafish Mouse
regulation of locomotion GO:0040012 329 0.054
Worm
metal ion transport GO:0030001 272 0.054
female gamete generation GO:0007292 2 0.054
positive regulation of glucocorticoid biosynthetic process GO:0031948 1 0.054
spinal cord development GO:0021510 4 0.053
blastoderm segmentation GO:0007350 2 0.053
cellular calcium ion homeostasis GO:0006874 117 0.051
regulation of cytokine production GO:0001817 232 0.051
sensory organ development GO:0007423 52 0.051
Human Zebrafish Mouse
regulation of transferase activity GO:0051338 355 0.050
multicellular organismal aging GO:0010259 3 0.050
nerve development GO:0021675 4 0.050
regulation of cell development GO:0060284 161 0.050
regulation of kinase activity GO:0043549 314 0.049
striated muscle tissue development GO:0014706 59 0.048
positive regulation of transport GO:0051050 336 0.048
cellular homeostasis GO:0019725 196 0.048
metencephalon development GO:0022037 2 0.048
cell adhesion GO:0007155 325 0.047
negative regulation of cell proliferation GO:0008285 228 0.047
inorganic cation transmembrane transport GO:0098662 194 0.047
regulation of secretion GO:0051046 194 0.047
regulation of cell cycle GO:0051726 393 0.047
cellular divalent inorganic cation homeostasis GO:0072503 128 0.046
pattern specification process GO:0007389 43 0.046
heart formation GO:0060914 2 0.046
immune system development GO:0002520 195 0.046
signal transduction by phosphorylation GO:0023014 297 0.046
tube morphogenesis GO:0035239 95 0.046
negative regulation of protein metabolic process GO:0051248 391 0.045
positive regulation of cell differentiation GO:0045597 211 0.045
sensory perception GO:0007600 103 0.044
blood vessel morphogenesis GO:0048514 162 0.044
cytoplasmic transport GO:0016482 379 0.043
cellular ion homeostasis GO:0006873 168 0.043
vasculature development GO:0001944 181 0.043
determination of adult lifespan GO:0008340 2 0.043
lipid metabolic process GO:0006629 381 0.043
regulation of protein serine threonine kinase activity GO:0071900 179 0.043
cardiac right ventricle morphogenesis GO:0003215 3 0.043
response to abiotic stimulus GO:0009628 336 0.043
cell morphogenesis GO:0000902 296 0.042
Worm Fly
negative regulation of apoptotic process GO:0043066 316 0.041
regulation of nucleotide metabolic process GO:0006140 269 0.041
kidney development GO:0001822 53 0.041
positive regulation of transferase activity GO:0051347 227 0.041
digestive tract development GO:0048565 75 0.040
regulation of protein kinase activity GO:0045859 289 0.040
mesenchyme development GO:0060485 59 0.040
response to organonitrogen compound GO:0010243 156 0.039
positive regulation of protein kinase activity GO:0045860 190 0.039
cell morphogenesis involved in differentiation GO:0000904 144 0.039
Worm Fly
calcium ion transport GO:0006816 147 0.039
regulation of homeostatic process GO:0032844 121 0.039
purine ribonucleotide catabolic process GO:0009154 404 0.039
regulation of cellular component movement GO:0051270 334 0.039
apoptotic signaling pathway GO:0097190 268 0.039
myoblast fusion GO:0007520 1 0.038
purine containing compound catabolic process GO:0072523 411 0.038
positive regulation of aldosterone metabolic process GO:0032346 2 0.038
negative regulation of programmed cell death GO:0043069 321 0.038
muscle tissue development GO:0060537 62 0.038
epithelial tube morphogenesis GO:0060562 38 0.038
regulation of hormone levels GO:0010817 125 0.038
oogenesis GO:0048477 2 0.038
nitrogen compound transport GO:0071705 191 0.038
angiogenesis GO:0001525 147 0.038
head development GO:0060322 108 0.038
Zebrafish Mouse
cytokine production GO:0001816 247 0.037
neurogenesis GO:0022008 169 0.037
Mouse Worm Fly
regulation of cell migration GO:0030334 289 0.037
positive regulation of protein phosphorylation GO:0001934 313 0.037
cellular cation homeostasis GO:0030003 163 0.037
cerebellum development GO:0021549 2 0.037
cellular response to dna damage stimulus GO:0006974 379 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.037
negative regulation of cell death GO:0060548 345 0.036
divalent inorganic cation transport GO:0072511 158 0.036
neuron differentiation GO:0030182 138 0.036
Mouse Worm Fly
inorganic ion transmembrane transport GO:0098660 231 0.036
specification of organ identity GO:0010092 3 0.036
actin filament based process GO:0030029 224 0.036
myeloid cell differentiation GO:0030099 117 0.036
chromatin organization GO:0006325 351 0.035
response to lipid GO:0033993 206 0.035
protein oligomerization GO:0051259 173 0.035
morphogenesis of embryonic epithelium GO:0016331 4 0.035
regionalization GO:0003002 29 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.035
response to hormone GO:0009725 175 0.035
chemical homeostasis GO:0048878 306 0.035
forebrain neuron differentiation GO:0021879 3 0.034
reproductive process GO:0022414 106 0.034
adult locomotory behavior GO:0008344 1 0.033
mapk cascade GO:0000165 288 0.033
immune response GO:0006955 307 0.033
regulation of ion transport GO:0043269 189 0.033
mitotic cell cycle GO:0000278 326 0.033
negative regulation of cell migration GO:0030336 102 0.033
positive regulation of apoptotic process GO:0043065 246 0.032
positive regulation of cell death GO:0010942 263 0.032
positive regulation of kinase activity GO:0033674 204 0.032
regulation of protein localization GO:0032880 296 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
ras protein signal transduction GO:0007265 73 0.032
nucleotide catabolic process GO:0009166 408 0.032
cell fate commitment GO:0045165 27 0.032
ribonucleotide catabolic process GO:0009261 405 0.032
inner ear morphogenesis GO:0042472 4 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.031
cellular lipid metabolic process GO:0044255 303 0.031
response to nitrogen compound GO:1901698 184 0.031
hemopoiesis GO:0030097 180 0.031
hormone metabolic process GO:0042445 61 0.031
somatic stem cell maintenance GO:0035019 4 0.031
muscle organ development GO:0007517 56 0.030
neuron projection development GO:0031175 106 0.030
Worm Fly
amide transport GO:0042886 76 0.030
memory GO:0007613 3 0.030
cellular response to organic cyclic compound GO:0071407 127 0.030
wnt signaling pathway GO:0016055 156 0.030
growth GO:0040007 202 0.030
associative learning GO:0008306 1 0.030
cellular response to hormone stimulus GO:0032870 125 0.030
regulation of cell motility GO:2000145 299 0.030
embryo development GO:0009790 123 0.030
calcium ion homeostasis GO:0055074 122 0.030
mesenchymal cell development GO:0014031 50 0.030
positive regulation of organelle organization GO:0010638 195 0.029
forebrain regionalization GO:0021871 3 0.029
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.029
forebrain development GO:0030900 26 0.029
Zebrafish
regulation of cell adhesion GO:0030155 166 0.029
divalent metal ion transport GO:0070838 152 0.029
negative regulation of protein modification process GO:0031400 200 0.029
syncytium formation by plasma membrane fusion GO:0000768 2 0.029
heart morphogenesis GO:0003007 48 0.028
positive regulation of programmed cell death GO:0043068 249 0.028
biological adhesion GO:0022610 331 0.028
purine nucleoside triphosphate metabolic process GO:0009144 412 0.028
sensory perception of light stimulus GO:0050953 35 0.028
regulation of mitotic cell cycle GO:0007346 189 0.028
covalent chromatin modification GO:0016569 254 0.028
testosterone biosynthetic process GO:0061370 2 0.028
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.028
positive regulation of immune system process GO:0002684 283 0.028
mesenchymal cell differentiation GO:0048762 52 0.028
fatty acid metabolic process GO:0006631 115 0.028
motor neuron axon guidance GO:0008045 2 0.028
organophosphate catabolic process GO:0046434 430 0.028
regulation of establishment of protein localization GO:0070201 242 0.027
mitotic cell cycle process GO:1903047 286 0.027
blood vessel development GO:0001568 172 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
limbic system development GO:0021761 3 0.026
cellular amide metabolic process GO:0043603 69 0.026
cellular response to nitrogen compound GO:1901699 144 0.026
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.026
regulation of protein transport GO:0051223 213 0.026
striated muscle contraction GO:0006941 52 0.026
striated muscle cell differentiation GO:0051146 43 0.026
peripheral nervous system development GO:0007422 2 0.026
negative regulation of transport GO:0051051 176 0.026
connective tissue development GO:0061448 39 0.026
purine nucleoside catabolic process GO:0006152 398 0.026
regulation of cellular component biogenesis GO:0044087 281 0.026
single organism cellular localization GO:1902580 332 0.025
visual learning GO:0008542 1 0.025
regulation of wnt signaling pathway GO:0030111 123 0.025
hormone secretion GO:0046879 65 0.025
negative regulation of cell cycle GO:0045786 193 0.025
regulation of vasculature development GO:1901342 97 0.025
chromatin modification GO:0016568 298 0.025
purine nucleotide catabolic process GO:0006195 405 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
urogenital system development GO:0001655 65 0.025
histone modification GO:0016570 251 0.025
cellular response to organonitrogen compound GO:0071417 124 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
cartilage condensation GO:0001502 1 0.025
response to disaccharide GO:0034285 1 0.025
protein localization to organelle GO:0033365 280 0.025
peptide metabolic process GO:0006518 51 0.025
cell growth GO:0016049 160 0.025
stem cell development GO:0048864 69 0.025
vesicle mediated transport GO:0016192 371 0.024
cell projection morphogenesis GO:0048858 129 0.024
Worm Fly
regulation of transmembrane transport GO:0034762 139 0.024
regulation of heart contraction GO:0008016 50 0.024
muscle system process GO:0003012 81 0.024
regulation of intracellular transport GO:0032386 195 0.024
membrane organization GO:0061024 292 0.024
monocarboxylic acid metabolic process GO:0032787 185 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
positive regulation of epithelial cell proliferation GO:0050679 65 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
regulation of growth GO:0040008 165 0.024
cation transmembrane transport GO:0098655 238 0.024
neuron development GO:0048666 113 0.024
Mouse Worm Fly
visual behavior GO:0007632 2 0.024
renal system development GO:0072001 63 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
neuromuscular junction development GO:0007528 3 0.024
regulation of nervous system development GO:0051960 88 0.024
negative regulation of phosphorylation GO:0042326 174 0.023
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.023
negative regulation of cellular component movement GO:0051271 106 0.023
response to radiation GO:0009314 151 0.023
signal release GO:0023061 70 0.023
regulation of multi organism process GO:0043900 157 0.023
muscle cell fate commitment GO:0042693 4 0.023
visual perception GO:0007601 27 0.023
brain development GO:0007420 97 0.023
Zebrafish Mouse
regulation of lipid metabolic process GO:0019216 96 0.023
positive regulation of secretion by cell GO:1903532 108 0.023
muscle cell differentiation GO:0042692 63 0.023
peptide secretion GO:0002790 51 0.023
neuron projection morphogenesis GO:0048812 50 0.023
Worm Fly
positive regulation of mapk cascade GO:0043410 190 0.022
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.022
regulation of cell cycle process GO:0010564 266 0.022
regulation of cellular response to stress GO:0080135 244 0.022
negative regulation of androgen biosynthetic process GO:2000180 1 0.022
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.022
negative regulation of protein phosphorylation GO:0001933 140 0.022
cytosolic calcium ion homeostasis GO:0051480 89 0.022
heart process GO:0003015 62 0.022
positive regulation of protein complex assembly GO:0031334 86 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
cardiac cell fate determination GO:0060913 3 0.022
eye development GO:0001654 42 0.022
Human Zebrafish Mouse
regulation of response to external stimulus GO:0032101 222 0.022
interspecies interaction between organisms GO:0044419 156 0.022
wound healing GO:0042060 115 0.022
cardiac muscle contraction GO:0060048 34 0.022
regulation of epithelial cell proliferation GO:0050678 113 0.022
canonical wnt signaling pathway GO:0060070 116 0.022
response to wounding GO:0009611 168 0.022
positive regulation of protein transport GO:0051222 135 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
protein catabolic process GO:0030163 325 0.021
cellular response to cytokine stimulus GO:0071345 181 0.021
heart contraction GO:0060047 62 0.021
extraocular skeletal muscle development GO:0002074 1 0.021
heart development GO:0007507 95 0.021
nucleoside catabolic process GO:0009164 408 0.021
regeneration GO:0031099 4 0.021
morphogenesis of an epithelium GO:0002009 60 0.021
regulation of immune response GO:0050776 201 0.021
small molecule biosynthetic process GO:0044283 157 0.021
regulation of ion transmembrane transporter activity GO:0032412 72 0.021
organelle assembly GO:0070925 176 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
mating GO:0007618 1 0.021
regulation of ion transmembrane transport GO:0034765 132 0.021
multi organism cellular process GO:0044764 156 0.021
regulation of cell growth GO:0001558 135 0.020
activation of protein kinase activity GO:0032147 90 0.020
dephosphorylation GO:0016311 209 0.020
positive regulation of cell development GO:0010720 92 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.020
gland development GO:0048732 48 0.020
Zebrafish
negative regulation of locomotion GO:0040013 118 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
behavior GO:0007610 112 0.020
Mouse
regulation of neurogenesis GO:0050767 82 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
embryonic epithelial tube formation GO:0001838 4 0.019
intracellular protein transport GO:0006886 270 0.019
endodermal cell fate specification GO:0001714 4 0.019
epidermis development GO:0008544 59 0.019
bmp signaling pathway GO:0030509 49 0.019
regulation of neuron differentiation GO:0045664 70 0.019
response to other organism GO:0051707 261 0.019
single organism cell adhesion GO:0098602 179 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
single organism membrane organization GO:0044802 268 0.019
regulation of dna metabolic process GO:0051052 153 0.019
neuroendocrine cell differentiation GO:0061101 2 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
osteoblast differentiation GO:0001649 92 0.019
regulation of cytoplasmic transport GO:1903649 149 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.019
secretion GO:0046903 254 0.019
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.019
regulation of cytoskeleton organization GO:0051493 177 0.019
negative regulation of immune system process GO:0002683 136 0.018
positive regulation of cytokine production GO:0001819 167 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
organonitrogen compound biosynthetic process GO:1901566 200 0.018
negative regulation of cell motility GO:2000146 104 0.018
single organism reproductive process GO:0044702 98 0.018
rhythmic behavior GO:0007622 2 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
regulation of proteolysis GO:0030162 293 0.018
response to cytokine GO:0034097 232 0.018
neural tube patterning GO:0021532 2 0.018
g protein coupled receptor signaling pathway GO:0007186 207 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.018
skin development GO:0043588 76 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
compound eye development GO:0048749 1 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
cell part morphogenesis GO:0032990 137 0.018
Worm Fly
sequestering of calcium ion GO:0051208 17 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
nuclear transport GO:0051169 179 0.017
cardiac muscle tissue development GO:0048738 39 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
carboxylic acid biosynthetic process GO:0046394 97 0.017
protein maturation GO:0051604 233 0.017
cell cycle phase transition GO:0044770 173 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
regulation of map kinase activity GO:0043405 108 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
mesodermal cell fate specification GO:0007501 2 0.017
regulation of canonical wnt signaling pathway GO:0060828 88 0.017
protein homooligomerization GO:0051260 100 0.017
negative regulation of cell development GO:0010721 48 0.017
protein processing GO:0016485 226 0.017
oxidation reduction process GO:0055114 396 0.017
somitogenesis GO:0001756 2 0.017
positive regulation of immune response GO:0050778 159 0.017
actin cytoskeleton organization GO:0030036 207 0.017
protein localization to nucleus GO:0034504 136 0.017
negative regulation of hydrolase activity GO:0051346 182 0.016
regulation of stem cell differentiation GO:2000736 56 0.016
response to biotic stimulus GO:0009607 276 0.016
negative regulation of transferase activity GO:0051348 124 0.016
regulation of myeloid cell differentiation GO:0045637 81 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
circadian behavior GO:0048512 2 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
regulation of transporter activity GO:0032409 82 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
lipid biosynthetic process GO:0008610 177 0.016
cortisol biosynthetic process GO:0034651 8 0.016
regulation of angiogenesis GO:0045765 92 0.016
cardiac ventricle formation GO:0003211 2 0.016
regulation of transmembrane transporter activity GO:0022898 74 0.016
ameboidal type cell migration GO:0001667 135 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
mitotic cell cycle phase transition GO:0044772 162 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
negative regulation of growth GO:0045926 97 0.015
regulation of blood circulation GO:1903522 59 0.015
response to axon injury GO:0048678 1 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
intracellular receptor signaling pathway GO:0030522 104 0.015
formation of primary germ layer GO:0001704 42 0.015
dna repair GO:0006281 198 0.015
regulation of actin filament based process GO:0032970 141 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.015
Worm Fly
negative regulation of kidney development GO:0090185 2 0.015
ossification GO:0001503 121 0.015
protein targeting GO:0006605 187 0.015
defense response GO:0006952 315 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
regulation of membrane potential GO:0042391 95 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.015
cellular modified amino acid metabolic process GO:0006575 64 0.015
regulation of synaptic plasticity GO:0048167 3 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
regulation of hormone secretion GO:0046883 57 0.014
cardiac muscle cell contraction GO:0086003 4 0.014
cell type specific apoptotic process GO:0097285 125 0.014
single organismal cell cell adhesion GO:0016337 148 0.014
negative regulation of kinase activity GO:0033673 106 0.014
response to external biotic stimulus GO:0043207 261 0.014
regulation of chromosome organization GO:0033044 103 0.014
positive regulation of cytoskeleton organization GO:0051495 83 0.014
positive regulation of intracellular transport GO:0032388 104 0.014
endocrine system development GO:0035270 26 0.014
Zebrafish
regulation of male gonad development GO:2000018 4 0.014
leukocyte differentiation GO:0002521 98 0.014
epithelial cell proliferation GO:0050673 128 0.014
positive regulation of blood pressure GO:0045777 3 0.014
blastocyst development GO:0001824 3 0.014
response to light stimulus GO:0009416 87 0.014
somatic muscle development GO:0007525 1 0.014
regulation of myoblast fusion GO:1901739 1 0.014
negative regulation of cell growth GO:0030308 83 0.014
gtp catabolic process GO:0006184 237 0.014
lens development in camera type eye GO:0002088 2 0.014
Zebrafish Mouse
myeloid leukocyte differentiation GO:0002573 60 0.014
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.014
positive regulation of secretion GO:0051047 116 0.014
positive regulation of nervous system development GO:0051962 54 0.014
regulation of actin cytoskeleton organization GO:0032956 116 0.014
developmental programmed cell death GO:0010623 3 0.014
tissue morphogenesis GO:0048729 96 0.014

PITX3 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.076
nervous system disease DOID:863 431 0.076
musculoskeletal system disease DOID:17 223 0.038
Human
disease of metabolism DOID:0014667 295 0.036
eye and adnexa disease DOID:1492 150 0.032
eye disease DOID:5614 149 0.028
retinal disease DOID:5679 118 0.028
disease of cellular proliferation DOID:14566 174 0.019
cancer DOID:162 167 0.018
muscular disease DOID:0080000 114 0.017
organ system cancer DOID:0050686 164 0.017
cardiovascular system disease DOID:1287 106 0.016
muscle tissue disease DOID:66 113 0.015