Homo sapiens

0 known processes

TXNDC5

thioredoxin domain containing 5 (endoplasmic reticulum)

(Aliases: MGC3178,HCC-2,UNQ364,ERP46,PDIA15,ENDOPDI,STRF8)

TXNDC5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organismal aging GO:0010259 3 0.254
protein oxidation GO:0018158 5 0.190
determination of adult lifespan GO:0008340 2 0.139
carbohydrate metabolic process GO:0005975 207 0.089
post embryonic development GO:0009791 2 0.080
ubiquitin dependent protein catabolic process GO:0006511 206 0.068
negative regulation of proteolysis GO:0045861 132 0.068
response to abiotic stimulus GO:0009628 336 0.067
modification dependent protein catabolic process GO:0019941 209 0.065
regulation of multi organism process GO:0043900 157 0.065
negative regulation of catalytic activity GO:0043086 335 0.064
negative regulation of protein processing GO:0010955 142 0.061
oxidation reduction process GO:0055114 396 0.060
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.060
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.056
regulation of protein processing GO:0070613 150 0.056
negative regulation of protein metabolic process GO:0051248 391 0.056
regulation of proteolysis GO:0030162 293 0.054
regulation of endopeptidase activity GO:0052548 170 0.053
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.052
regulation of peptidase activity GO:0052547 180 0.052
hydrogen peroxide catabolic process GO:0042744 13 0.052
mitochondrion organization GO:0007005 156 0.051
cellular amino acid metabolic process GO:0006520 116 0.050
negative regulation of protein maturation GO:1903318 142 0.050
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.048
glycoprotein metabolic process GO:0009100 110 0.048
negative regulation of phosphorylation GO:0042326 174 0.047
glycoprotein biosynthetic process GO:0009101 91 0.046
negative regulation of apoptotic process GO:0043066 316 0.044
cellular response to superoxide GO:0071451 6 0.044
negative regulation of phosphate metabolic process GO:0045936 267 0.043
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.042
negative regulation of phosphorus metabolic process GO:0010563 267 0.042
protein processing GO:0016485 226 0.042
modification dependent macromolecule catabolic process GO:0043632 212 0.038
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.038
protein maturation GO:0051604 233 0.038
cellular modified amino acid metabolic process GO:0006575 64 0.038
response to oxygen containing compound GO:1901700 369 0.036
protein glycosylation GO:0006486 62 0.035
cellular protein catabolic process GO:0044257 261 0.035
multicellular organismal homeostasis GO:0048871 67 0.034
cellular response to oxygen containing compound GO:1901701 276 0.034
regulation of cysteine type endopeptidase activity GO:2000116 127 0.034
reactive oxygen species metabolic process GO:0072593 75 0.033
regulation of protein maturation GO:1903317 150 0.031
regulation of growth GO:0040008 165 0.031
response to inorganic substance GO:0010035 127 0.031
regulation of kinase activity GO:0043549 314 0.030
single organism carbohydrate metabolic process GO:0044723 193 0.030
positive regulation of cell proliferation GO:0008284 301 0.029
negative regulation of endopeptidase activity GO:0010951 84 0.029
negative regulation of hydrolase activity GO:0051346 182 0.029
carbohydrate derivative biosynthetic process GO:1901137 207 0.029
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.029
vesicle mediated transport GO:0016192 371 0.028
Fly
cellular response to oxidative stress GO:0034599 85 0.028
monocarboxylic acid metabolic process GO:0032787 185 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.028
cellular homeostasis GO:0019725 196 0.028
protein catabolic process GO:0030163 325 0.027
cellular response to hydrogen peroxide GO:0070301 37 0.027
negative regulation of multi organism process GO:0043901 92 0.027
negative regulation of transferase activity GO:0051348 124 0.026
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.026
glycosylation GO:0070085 71 0.026
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.026
cellular macromolecule catabolic process GO:0044265 380 0.025
positive regulation of developmental process GO:0051094 314 0.025
endoplasmic reticulum organization GO:0007029 20 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
response to bacterium GO:0009617 144 0.024
superoxide metabolic process GO:0006801 20 0.023
regulation of protein localization GO:0032880 296 0.023
protein localization to nucleus GO:0034504 136 0.023
positive regulation of cell death GO:0010942 263 0.023
negative regulation of cell proliferation GO:0008285 228 0.023
cellular amine metabolic process GO:0044106 41 0.023
peptidyl cysteine modification GO:0018198 9 0.022
regeneration GO:0031099 4 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
alpha amino acid metabolic process GO:1901605 72 0.022
negative regulation of kinase activity GO:0033673 106 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
regulation of membrane potential GO:0042391 95 0.021
cellular response to dna damage stimulus GO:0006974 379 0.020
hydrogen peroxide metabolic process GO:0042743 20 0.020
protein folding GO:0006457 38 0.020
cation transport GO:0006812 331 0.020
anatomical structure homeostasis GO:0060249 100 0.020
axon regeneration GO:0031103 1 0.019
endomembrane system organization GO:0010256 196 0.019
cellular ketone metabolic process GO:0042180 80 0.019
camp biosynthetic process GO:0006171 47 0.019
response to oxidative stress GO:0006979 121 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
lipid metabolic process GO:0006629 381 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.018
photoreceptor cell differentiation GO:0046530 2 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
peptidyl cysteine oxidation GO:0018171 1 0.018
defense response GO:0006952 315 0.018
circulatory system process GO:0003013 113 0.018
growth GO:0040007 202 0.017
cell division GO:0051301 168 0.017
single organism cellular localization GO:1902580 332 0.017
actin filament based process GO:0030029 224 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
hindbrain development GO:0030902 3 0.017
protein ubiquitination GO:0016567 314 0.017
nucleotide catabolic process GO:0009166 408 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
response to metal ion GO:0010038 84 0.017
i kappab kinase nf kappab signaling GO:0007249 166 0.017
chromatin modification GO:0016568 298 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
cellular response to reactive oxygen species GO:0034614 50 0.016
negative regulation of cell death GO:0060548 345 0.016
immune response GO:0006955 307 0.016
ion homeostasis GO:0050801 230 0.016
negative regulation of peptidase activity GO:0010466 91 0.016
regulation of transferase activity GO:0051338 355 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
positive regulation of phosphorylation GO:0042327 394 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
coagulation GO:0050817 78 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
positive regulation of kinase activity GO:0033674 204 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
regulation of defense response GO:0031347 154 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
regulation of cellular response to stress GO:0080135 244 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
regulation of cell motility GO:2000145 299 0.015
reproductive process GO:0022414 106 0.014
neurotransmitter secretion GO:0007269 4 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.014
protein localization to organelle GO:0033365 280 0.014
primary neural tube formation GO:0014020 3 0.014
amine metabolic process GO:0009308 44 0.014
protein o linked glycosylation via serine GO:0018242 3 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
cellular response to topologically incorrect protein GO:0035967 19 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
regulation of cellular component movement GO:0051270 334 0.014
cellular response to hormone stimulus GO:0032870 125 0.013
cell adhesion GO:0007155 325 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.013
aging GO:0007568 66 0.013
positive regulation of catabolic process GO:0009896 310 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
embryo development GO:0009790 123 0.013
ras protein signal transduction GO:0007265 73 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.013
mitotic cell cycle GO:0000278 326 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
neuromuscular junction development GO:0007528 3 0.013
regulation of protein complex assembly GO:0043254 147 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
tissue homeostasis GO:0001894 63 0.013
locomotory behavior GO:0007626 1 0.013
eye photoreceptor cell differentiation GO:0001754 2 0.013
chromatin organization GO:0006325 351 0.013
negative regulation of developmental process GO:0051093 247 0.013
response to external biotic stimulus GO:0043207 261 0.013
nitrogen compound transport GO:0071705 191 0.013
positive regulation of transferase activity GO:0051347 227 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
glycosyl compound catabolic process GO:1901658 413 0.012
regulation of mitochondrial membrane potential GO:0051881 23 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
response to biotic stimulus GO:0009607 276 0.012
regulation of response to external stimulus GO:0032101 222 0.012
single organism nuclear import GO:1902593 104 0.012
dephosphorylation GO:0016311 209 0.012
multi organism cellular process GO:0044764 156 0.012
transmembrane transport GO:0055085 399 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.012
protein targeting to nucleus GO:0044744 104 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
protein import GO:0017038 130 0.012
male gonad development GO:0008584 23 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
actin cytoskeleton organization GO:0030036 207 0.012
ion transmembrane transport GO:0034220 338 0.012
response to hydrogen peroxide GO:0042542 40 0.012
response to growth factor GO:0070848 205 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
Fly
regulation of ion transport GO:0043269 189 0.012
regulation of cell migration GO:0030334 289 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
cytokinesis GO:0000910 96 0.012
single organism membrane organization GO:0044802 268 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
segmentation GO:0035282 4 0.012
male genitalia development GO:0030539 1 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
female gamete generation GO:0007292 2 0.011
peptidyl lysine modification GO:0018205 144 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
regulation of locomotion GO:0040012 329 0.011
mitotic cell cycle process GO:1903047 286 0.011
interspecies interaction between organisms GO:0044419 156 0.011
regulation of cell differentiation GO:0045595 393 0.011
blood circulation GO:0008015 113 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
regulation of cellular amine metabolic process GO:0033238 11 0.011
cellular response to lipid GO:0071396 127 0.011
macromolecule glycosylation GO:0043413 63 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
nervous system development GO:0007399 293 0.011
innate immune response GO:0045087 178 0.011
response to topologically incorrect protein GO:0035966 29 0.011
retina homeostasis GO:0001895 42 0.011
regulation of protein transport GO:0051223 213 0.011
cellular component morphogenesis GO:0032989 314 0.011
regulation of intracellular transport GO:0032386 195 0.011
mapk cascade GO:0000165 288 0.011
cell development GO:0048468 328 0.011
cellular macromolecular complex assembly GO:0034622 324 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
extracellular structure organization GO:0043062 41 0.011
thymus development GO:0048538 3 0.011
metal ion transport GO:0030001 272 0.011
response to molecule of bacterial origin GO:0002237 82 0.011
negative regulation of protein modification process GO:0031400 200 0.011
cellular response to external stimulus GO:0071496 111 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
removal of superoxide radicals GO:0019430 6 0.011
microtubule based process GO:0007017 210 0.011
actin mediated cell contraction GO:0070252 12 0.011
protein targeting GO:0006605 187 0.011
embryonic epithelial tube formation GO:0001838 4 0.010
leukocyte activation GO:0045321 164 0.010
regulation of metal ion transport GO:0010959 120 0.010
nucleoside triphosphate metabolic process GO:0009141 422 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
cell morphogenesis GO:0000902 296 0.010
negative regulation of cell differentiation GO:0045596 171 0.010
negative regulation of eosinophil extravasation GO:2000420 1 0.010
regulation of eosinophil extravasation GO:2000419 1 0.010
extracellular matrix organization GO:0030198 41 0.010
nuclear transport GO:0051169 179 0.010
hemopoiesis GO:0030097 180 0.010
synaptic vesicle endocytosis GO:0048488 2 0.010
organophosphate catabolic process GO:0046434 430 0.010
cell activation GO:0001775 213 0.010
regulation of mapk cascade GO:0043408 262 0.010

TXNDC5 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.028
connective tissue disease DOID:65 109 0.025
bone disease DOID:0080001 88 0.017
disease of metabolism DOID:0014667 295 0.016
bone development disease DOID:0080006 55 0.016
inherited metabolic disorder DOID:655 242 0.015
sensory system disease DOID:0050155 203 0.014
nervous system disease DOID:863 431 0.014
disease of cellular proliferation DOID:14566 174 0.013
cancer DOID:162 167 0.012
organ system cancer DOID:0050686 164 0.012
eye and adnexa disease DOID:1492 150 0.011
retinal disease DOID:5679 118 0.010
eye disease DOID:5614 149 0.010