Homo sapiens

155 known processes

NSMCE2

non-SMC element 2, MMS21 homolog (S. cerevisiae)

(Aliases: FLJ32440,MMS21,C8orf36,NSE2)

NSMCE2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair GO:0006302 101 0.271
protein modification by small protein conjugation GO:0032446 342 0.247
cellular response to dna damage stimulus GO:0006974 379 0.240
double strand break repair via homologous recombination GO:0000724 50 0.117
post embryonic development GO:0009791 2 0.096
negative regulation of protein metabolic process GO:0051248 391 0.068
positive regulation of response to dna damage stimulus GO:2001022 43 0.059
regulation of cell cycle GO:0051726 393 0.055
modification dependent macromolecule catabolic process GO:0043632 212 0.054
recombinational repair GO:0000725 50 0.052
cellular macromolecule catabolic process GO:0044265 380 0.046
proteasomal protein catabolic process GO:0010498 176 0.045
regulation of proteolysis GO:0030162 293 0.041
cellular senescence GO:0090398 34 0.040
protein ubiquitination GO:0016567 314 0.039
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.037
positive regulation of proteolysis GO:0045862 142 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.035
chromosome segregation GO:0007059 114 0.035
positive regulation of transferase activity GO:0051347 227 0.034
protein acetylation GO:0006473 116 0.034
regulation of cellular response to stress GO:0080135 244 0.033
response to organic cyclic compound GO:0014070 204 0.033
negative regulation of protein modification process GO:0031400 200 0.032
protein acylation GO:0043543 138 0.032
protein maturation GO:0051604 233 0.032
cell aging GO:0007569 52 0.031
positive regulation of hydrolase activity GO:0051345 331 0.030
protein processing GO:0016485 226 0.030
regulation of cell differentiation GO:0045595 393 0.029
female gamete generation GO:0007292 2 0.028
dna repair GO:0006281 198 0.028
cellular lipid metabolic process GO:0044255 303 0.028
regulation of cellular amine metabolic process GO:0033238 11 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
dna recombination GO:0006310 77 0.027
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.026
cellular protein catabolic process GO:0044257 261 0.026
positive regulation of catabolic process GO:0009896 310 0.026
amine metabolic process GO:0009308 44 0.026
negative regulation of protein processing GO:0010955 142 0.026
chromosome separation GO:0051304 23 0.026
modification dependent protein catabolic process GO:0019941 209 0.025
telomere organization GO:0032200 33 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
single organism cellular localization GO:1902580 332 0.024
segmentation GO:0035282 4 0.024
cellular amine metabolic process GO:0044106 41 0.024
lipid biosynthetic process GO:0008610 177 0.024
response to nitrogen compound GO:1901698 184 0.024
regulation of cellular ketone metabolic process GO:0010565 50 0.024
protein catabolic process GO:0030163 325 0.024
cellular ketone metabolic process GO:0042180 80 0.024
neuromuscular junction development GO:0007528 3 0.023
dna conformation change GO:0071103 113 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.023
mitotic sister chromatid separation GO:0051306 18 0.022
cellular amino acid metabolic process GO:0006520 116 0.022
oocyte development GO:0048599 1 0.022
embryo development GO:0009790 123 0.021
response to abiotic stimulus GO:0009628 336 0.021
membrane organization GO:0061024 292 0.021
regulation of cell cycle phase transition GO:1901987 126 0.021
endomembrane system organization GO:0010256 196 0.020
regulation of protein catabolic process GO:0042176 155 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.020
regulation of mitotic cell cycle GO:0007346 189 0.020
determination of adult lifespan GO:0008340 2 0.020
regulation of nuclear division GO:0051783 65 0.020
negative regulation of proteolysis GO:0045861 132 0.019
response to caffeine GO:0031000 3 0.019
anterior posterior axis specification GO:0009948 2 0.019
negative regulation of protein maturation GO:1903318 142 0.019
regulation of protein localization GO:0032880 296 0.019
cell division GO:0051301 168 0.019
lipid metabolic process GO:0006629 381 0.019
regulation of response to dna damage stimulus GO:2001020 94 0.018
cytoplasmic transport GO:0016482 379 0.018
regulation of proteasomal protein catabolic process GO:0061136 87 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
cell projection organization GO:0030030 252 0.018
single organism membrane organization GO:0044802 268 0.018
dephosphorylation GO:0016311 209 0.017
immune response GO:0006955 307 0.017
chromatin modification GO:0016568 298 0.017
small gtpase mediated signal transduction GO:0007264 78 0.017
defense response GO:0006952 315 0.017
oogenesis GO:0048477 2 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
locomotory behavior GO:0007626 1 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.017
mitotic sister chromatid segregation GO:0000070 53 0.016
positive regulation of organelle organization GO:0010638 195 0.016
rna processing GO:0006396 255 0.016
meiotic chromosome segregation GO:0045132 4 0.016
regeneration GO:0031099 4 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
positive regulation of mitotic cell cycle GO:0045931 60 0.016
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
secretion GO:0046903 254 0.015
intracellular protein transport GO:0006886 270 0.015
regulation of kinase activity GO:0043549 314 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
response to oxygen containing compound GO:1901700 369 0.015
regulation of growth GO:0040008 165 0.015
ras protein signal transduction GO:0007265 73 0.015
translation GO:0006412 132 0.015
epithelial cell proliferation GO:0050673 128 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
regulation of mitotic sister chromatid segregation GO:0033047 27 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
signal transduction by phosphorylation GO:0023014 297 0.014
sister chromatid cohesion GO:0007062 24 0.014
protein localization to nucleus GO:0034504 136 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
multicellular organismal aging GO:0010259 3 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
maintenance of location GO:0051235 112 0.014
tripartite regional subdivision GO:0007351 2 0.014
methylation GO:0032259 106 0.014
response to other organism GO:0051707 261 0.014
regulation of protein processing GO:0070613 150 0.014
system process GO:0003008 349 0.014
nucleotide catabolic process GO:0009166 408 0.014
organophosphate catabolic process GO:0046434 430 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
rho protein signal transduction GO:0007266 26 0.014
chemical homeostasis GO:0048878 306 0.013
peptidyl lysine modification GO:0018205 144 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
cell morphogenesis GO:0000902 296 0.013
regulation of epithelial cell proliferation GO:0050678 113 0.013
nerve development GO:0021675 4 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
regulation of protein kinase activity GO:0045859 289 0.013
adult locomotory behavior GO:0008344 1 0.013
alcohol metabolic process GO:0006066 114 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
positive regulation of transport GO:0051050 336 0.013
ncrna metabolic process GO:0034660 108 0.013
cellular component morphogenesis GO:0032989 314 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
regulation of protein maturation GO:1903317 150 0.013
vesicle mediated transport GO:0016192 371 0.012
negative regulation of cell death GO:0060548 345 0.012
regulation of transferase activity GO:0051338 355 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
regulation of mitosis GO:0007088 63 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
blastoderm segmentation GO:0007350 2 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
peripheral nervous system development GO:0007422 2 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
peptidyl lysine acetylation GO:0018394 101 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
negative regulation of cell cycle GO:0045786 193 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
translational initiation GO:0006413 48 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
cell development GO:0048468 328 0.012
regulation of peptidase activity GO:0052547 180 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
negative regulation of developmental process GO:0051093 247 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
response to purine containing compound GO:0014074 40 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
regulation of cell division GO:0051302 116 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
regulation of cellular component movement GO:0051270 334 0.011
mitotic cell cycle GO:0000278 326 0.011
negative regulation of catabolic process GO:0009895 104 0.011
purine containing compound catabolic process GO:0072523 411 0.011
positive regulation of immune system process GO:0002684 283 0.011
positive regulation of developmental process GO:0051094 314 0.011
circulatory system development GO:0072359 262 0.011
organelle assembly GO:0070925 176 0.011
memory GO:0007613 3 0.011
regulation of gtpase activity GO:0043087 180 0.011
regulation of protein transport GO:0051223 213 0.011
negative regulation of organelle organization GO:0010639 126 0.011
protein targeting GO:0006605 187 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
positive regulation of cell death GO:0010942 263 0.011
cation homeostasis GO:0055080 189 0.011
cellular homeostasis GO:0019725 196 0.011
protein localization to organelle GO:0033365 280 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
regulation of protein stability GO:0031647 87 0.011
positive regulation of protein catabolic process GO:0045732 75 0.011
innate immune response GO:0045087 178 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
cytokine production GO:0001816 247 0.011
spermatid differentiation GO:0048515 4 0.011
positive regulation of cellular protein catabolic process GO:1903364 37 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
regulation of intracellular transport GO:0032386 195 0.010
mrna processing GO:0006397 133 0.010
generation of neurons GO:0048699 152 0.010
monocarboxylic acid metabolic process GO:0032787 185 0.010
response to fungus GO:0009620 4 0.010
positive regulation of gtpase activity GO:0043547 166 0.010
cell projection morphogenesis GO:0048858 129 0.010
positive regulation of cell cycle process GO:0090068 106 0.010
nucleoside triphosphate catabolic process GO:0009143 394 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
gtp metabolic process GO:0046039 239 0.010
response to external biotic stimulus GO:0043207 261 0.010
mapk cascade GO:0000165 288 0.010
actin filament based process GO:0030029 224 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
cellular protein complex assembly GO:0043623 188 0.010
ion homeostasis GO:0050801 230 0.010
macromolecule methylation GO:0043414 97 0.010
metal ion transport GO:0030001 272 0.010
regulation of cytokine production GO:0001817 232 0.010
cell part morphogenesis GO:0032990 137 0.010

NSMCE2 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
organ system cancer DOID:0050686 164 0.017
central nervous system disease DOID:331 186 0.017
nervous system disease DOID:863 431 0.017
sensory system disease DOID:0050155 203 0.013
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013
disease of metabolism DOID:0014667 295 0.012