Homo sapiens

0 known processes

COBRA1

cofactor of BRCA1

(Aliases: DKFZp586B0519,NELFB,NELF-B,KIAA1182)

COBRA1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.979
regulation of transcription during mitosis GO:0045896 2 0.929
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 4 0.919
dna templated transcription elongation GO:0006354 25 0.777
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.430
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.379
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.346
ras protein signal transduction GO:0007265 73 0.342
negative regulation of dna templated transcription elongation GO:0032785 6 0.262
small gtpase mediated signal transduction GO:0007264 78 0.225
regulation of cell cycle GO:0051726 393 0.200
anterior posterior axis specification embryo GO:0008595 2 0.175
purine ribonucleoside catabolic process GO:0046130 398 0.172
ribonucleoside triphosphate catabolic process GO:0009203 391 0.162
regulation of dna templated transcription elongation GO:0032784 23 0.156
purine nucleoside triphosphate metabolic process GO:0009144 412 0.149
neurogenesis GO:0022008 169 0.138
purine nucleoside triphosphate catabolic process GO:0009146 392 0.133
oocyte differentiation GO:0009994 2 0.131
positive regulation of transport GO:0051050 336 0.110
purine nucleoside catabolic process GO:0006152 398 0.109
nucleoside triphosphate catabolic process GO:0009143 394 0.109
nucleoside triphosphate metabolic process GO:0009141 422 0.106
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.106
segmentation GO:0035282 4 0.105
oogenesis GO:0048477 2 0.099
purine ribonucleotide catabolic process GO:0009154 404 0.098
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.098
nervous system development GO:0007399 293 0.087
blastoderm segmentation GO:0007350 2 0.084
histone modification GO:0016570 251 0.080
mitotic cell cycle process GO:1903047 286 0.080
positive regulation of cellular amine metabolic process GO:0033240 7 0.079
nucleoside catabolic process GO:0009164 408 0.079
ribonucleotide catabolic process GO:0009261 405 0.078
glycosyl compound catabolic process GO:1901658 413 0.076
cellular amino acid metabolic process GO:0006520 116 0.076
intracellular mrna localization GO:0008298 1 0.072
oocyte development GO:0048599 1 0.072
tripartite regional subdivision GO:0007351 2 0.071
organophosphate catabolic process GO:0046434 430 0.069
nucleoside phosphate catabolic process GO:1901292 412 0.068
regulation of multi organism process GO:0043900 157 0.066
purine nucleotide catabolic process GO:0006195 405 0.065
signal transduction by phosphorylation GO:0023014 297 0.064
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.064
cell division GO:0051301 168 0.063
gtp metabolic process GO:0046039 239 0.061
purine nucleoside monophosphate catabolic process GO:0009128 158 0.059
regulation of transferase activity GO:0051338 355 0.058
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
cellular response to dna damage stimulus GO:0006974 379 0.052
regulation of mitotic cell cycle GO:0007346 189 0.051
positive regulation of cell death GO:0010942 263 0.051
regulation of cellular amine metabolic process GO:0033238 11 0.050
proteasomal protein catabolic process GO:0010498 176 0.049
cytokinesis GO:0000910 96 0.048
protein catabolic process GO:0030163 325 0.047
negative regulation of phosphorus metabolic process GO:0010563 267 0.047
regulation of cellular ketone metabolic process GO:0010565 50 0.047
purine containing compound catabolic process GO:0072523 411 0.046
regulation of protein kinase activity GO:0045859 289 0.046
anterior posterior axis specification GO:0009948 2 0.046
dna damage checkpoint GO:0000077 68 0.046
protein modification by small protein conjugation GO:0032446 342 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.045
chromatin modification GO:0016568 298 0.044
vesicle mediated transport GO:0016192 371 0.044
cell cycle checkpoint GO:0000075 117 0.044
cellular amine metabolic process GO:0044106 41 0.044
atp metabolic process GO:0046034 176 0.043
gtp catabolic process GO:0006184 237 0.042
nucleotide catabolic process GO:0009166 408 0.041
organelle assembly GO:0070925 176 0.040
negative regulation of phosphate metabolic process GO:0045936 267 0.039
regulation of cell cycle phase transition GO:1901987 126 0.039
regulation of mapk cascade GO:0043408 262 0.038
guanosine containing compound catabolic process GO:1901069 239 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
regulation of kinase activity GO:0043549 314 0.038
female gamete generation GO:0007292 2 0.037
single organism cellular localization GO:1902580 332 0.036
negative regulation of protein metabolic process GO:0051248 391 0.036
positive regulation of cell differentiation GO:0045597 211 0.035
hindbrain development GO:0030902 3 0.034
cellular macromolecular complex assembly GO:0034622 324 0.034
regulation of response to external stimulus GO:0032101 222 0.034
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
actin cytoskeleton organization GO:0030036 207 0.034
post embryonic development GO:0009791 2 0.034
growth GO:0040007 202 0.034
regulation of viral process GO:0050792 103 0.034
response to starvation GO:0042594 59 0.033
mrna metabolic process GO:0016071 175 0.032
single organism reproductive process GO:0044702 98 0.032
negative regulation of protein modification process GO:0031400 200 0.032
response to fungus GO:0009620 4 0.032
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.032
multi organism cellular process GO:0044764 156 0.031
regulation of small gtpase mediated signal transduction GO:0051056 156 0.031
regulation of nucleotide catabolic process GO:0030811 205 0.030
purine ribonucleoside metabolic process GO:0046128 437 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.030
cellular response to starvation GO:0009267 58 0.030
regulation of protein localization GO:0032880 296 0.029
cell junction assembly GO:0034329 67 0.029
intracellular protein transport GO:0006886 270 0.029
ribonucleoside triphosphate metabolic process GO:0009199 412 0.029
generation of neurons GO:0048699 152 0.029
actin filament based process GO:0030029 224 0.029
atp catabolic process GO:0006200 157 0.028
mapk cascade GO:0000165 288 0.028
determination of adult lifespan GO:0008340 2 0.028
thymus development GO:0048538 3 0.027
dna biosynthetic process GO:0071897 40 0.027
vesicle organization GO:0016050 62 0.026
cellular component morphogenesis GO:0032989 314 0.026
regulation of cell development GO:0060284 161 0.026
ribonucleoprotein complex subunit organization GO:0071826 81 0.026
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.026
negative regulation of transport GO:0051051 176 0.026
synaptic transmission GO:0007268 61 0.026
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.026
amine metabolic process GO:0009308 44 0.026
locomotory behavior GO:0007626 1 0.026
g protein coupled receptor signaling pathway GO:0007186 207 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
regulation of cellular response to stress GO:0080135 244 0.024
peptidyl lysine acetylation GO:0018394 101 0.024
negative regulation of cell cycle GO:0045786 193 0.024
positive regulation of cellular component organization GO:0051130 376 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
regulation of ras gtpase activity GO:0032318 128 0.023
positive regulation of apoptotic process GO:0043065 246 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
regulation of mitotic cell cycle phase transition GO:1901990 118 0.023
regulation of response to dna damage stimulus GO:2001020 94 0.023
protein ubiquitination GO:0016567 314 0.023
chromatin organization GO:0006325 351 0.023
cellular ketone metabolic process GO:0042180 80 0.022
inner ear morphogenesis GO:0042472 4 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
positive regulation of gtp catabolic process GO:0033126 166 0.022
immune system development GO:0002520 195 0.022
cellular response to external stimulus GO:0071496 111 0.022
cell cell signaling GO:0007267 155 0.022
regulation of ras protein signal transduction GO:0046578 155 0.022
biological adhesion GO:0022610 331 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.022
dna integrity checkpoint GO:0031570 71 0.021
ribonucleoside monophosphate catabolic process GO:0009158 158 0.021
regulation of gtp catabolic process GO:0033124 180 0.021
regulation of purine nucleotide catabolic process GO:0033121 205 0.021
viral life cycle GO:0019058 132 0.021
protein localization to organelle GO:0033365 280 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
regulation of locomotion GO:0040012 329 0.020
metencephalon development GO:0022037 2 0.020
positive regulation of transferase activity GO:0051347 227 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
regulation of intracellular transport GO:0032386 195 0.020
cardiovascular system development GO:0072358 262 0.020
immune response GO:0006955 307 0.019
maintenance of location GO:0051235 112 0.019
cell morphogenesis GO:0000902 296 0.019
regulation of intracellular protein transport GO:0033157 123 0.019
regulation of cytokinesis GO:0032465 45 0.019
membrane organization GO:0061024 292 0.019
neuron projection development GO:0031175 106 0.019
regulation of cell motility GO:2000145 299 0.019
secretion by cell GO:0032940 226 0.019
regulation of cell division GO:0051302 116 0.018
neuron differentiation GO:0030182 138 0.018
positive regulation of protein phosphorylation GO:0001934 313 0.018
defense response to fungus GO:0050832 4 0.018
regulation of oocyte development GO:0060281 1 0.018
meiotic chromosome segregation GO:0045132 4 0.018
negative regulation of mitotic cell cycle GO:0045930 102 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
positive regulation of ras gtpase activity GO:0032320 117 0.018
rna processing GO:0006396 255 0.018
regulation of secretion by cell GO:1903530 177 0.017
cell cycle phase transition GO:0044770 173 0.017
negative regulation of cell death GO:0060548 345 0.017
protein processing GO:0016485 226 0.017
negative regulation of transferase activity GO:0051348 124 0.017
negative regulation of phagocytosis GO:0050765 4 0.017
regulation of binding GO:0051098 111 0.017
response to hormone GO:0009725 175 0.017
positive regulation of hydrolase activity GO:0051345 331 0.016
lipid metabolic process GO:0006629 381 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
regeneration GO:0031099 4 0.016
regulation of dna replication GO:0006275 68 0.016
regulation of autophagy GO:0010506 52 0.016
g2 m transition of mitotic cell cycle GO:0000086 41 0.016
regulation of gtpase activity GO:0043087 180 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
microtubule based process GO:0007017 210 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
microtubule cytoskeleton organization GO:0000226 176 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
macromolecular complex disassembly GO:0032984 60 0.015
meiosis i GO:0007127 4 0.015
cation homeostasis GO:0055080 189 0.015
positive regulation of organelle organization GO:0010638 195 0.015
negative regulation of kinase activity GO:0033673 106 0.015
cell adhesion GO:0007155 325 0.015
response to extracellular stimulus GO:0009991 85 0.015
defense response GO:0006952 315 0.015
protein autophosphorylation GO:0046777 123 0.014
protein polyubiquitination GO:0000209 110 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
reproductive process GO:0022414 106 0.014
neuromuscular junction development GO:0007528 3 0.014
innate immune response GO:0045087 178 0.014
response to organonitrogen compound GO:0010243 156 0.014
response to abiotic stimulus GO:0009628 336 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
multi organism reproductive process GO:0044703 54 0.014
cellular component disassembly GO:0022411 92 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
regulation of viral release from host cell GO:1902186 20 0.013
multicellular organism reproduction GO:0032504 42 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
protein localization to nucleus GO:0034504 136 0.013
response to oxygen containing compound GO:1901700 369 0.013
macroautophagy GO:0016236 39 0.013
multicellular organismal aging GO:0010259 3 0.013
compound eye development GO:0048749 1 0.013
chromosome segregation GO:0007059 114 0.013
alcohol metabolic process GO:0006066 114 0.013
regulation of immune response GO:0050776 201 0.012
microtubule organizing center organization GO:0031023 62 0.012
response to wounding GO:0009611 168 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
positive regulation of cytoskeleton organization GO:0051495 83 0.012
endomembrane system organization GO:0010256 196 0.012
ncrna processing GO:0034470 83 0.012
cellular protein complex assembly GO:0043623 188 0.012
regulation of secretion GO:0051046 194 0.012
regulation of growth GO:0040008 165 0.012
interspecies interaction between organisms GO:0044419 156 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
ncrna metabolic process GO:0034660 108 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
single organism nuclear import GO:1902593 104 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
cell development GO:0048468 328 0.012
regulation of peptidase activity GO:0052547 180 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
secretion GO:0046903 254 0.011
convergent extension GO:0060026 1 0.011
cell projection morphogenesis GO:0048858 129 0.011
protein oligomerization GO:0051259 173 0.011
neurotransmitter secretion GO:0007269 4 0.011
head development GO:0060322 108 0.011
organelle fission GO:0048285 149 0.011
gastrulation GO:0007369 51 0.011
regulation of interleukin 2 secretion GO:1900040 2 0.011
actin filament organization GO:0007015 128 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
regulation of dna metabolic process GO:0051052 153 0.011
positive regulation of dna metabolic process GO:0051054 73 0.011
regulation of cell projection organization GO:0031344 107 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
cellular component assembly involved in morphogenesis GO:0010927 73 0.011
dephosphorylation GO:0016311 209 0.011
rhythmic behavior GO:0007622 2 0.011
vasculature development GO:0001944 181 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
positive regulation of neurogenesis GO:0050769 49 0.011
reproduction GO:0000003 63 0.011
cell cycle g2 m phase transition GO:0044839 43 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
response to ionizing radiation GO:0010212 65 0.011
response to biotic stimulus GO:0009607 276 0.010
protein methylation GO:0006479 74 0.010
mitotic dna damage checkpoint GO:0044773 28 0.010
positive regulation of nucleotide metabolic process GO:0045981 230 0.010
viral process GO:0016032 146 0.010
nuclear division GO:0000280 128 0.010
endocytosis GO:0006897 159 0.010
regulation of response to wounding GO:1903034 101 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.010
protein import into nucleus GO:0006606 104 0.010
response to organic cyclic compound GO:0014070 204 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
regulation of cellular component movement GO:0051270 334 0.010
positive regulation of secretion by cell GO:1903532 108 0.010
regulation of cell migration GO:0030334 289 0.010

COBRA1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.031
disease of cellular proliferation DOID:14566 174 0.031
organ system cancer DOID:0050686 164 0.017