Homo sapiens

6 known processes

KIF5A

kinesin family member 5A

(Aliases: SPG10,MY050,NKHC,D12S1889)

KIF5A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 207 0.204
post embryonic development GO:0009791 2 0.152
transmembrane transport GO:0055085 399 0.138
nucleotide catabolic process GO:0009166 408 0.137
regulation of neuronal synaptic plasticity GO:0048168 1 0.135
locomotory behavior GO:0007626 1 0.117
Fly
metal ion transport GO:0030001 272 0.109
Human
memory GO:0007613 3 0.106
nucleoside triphosphate catabolic process GO:0009143 394 0.103
mating GO:0007618 1 0.100
synaptic transmission GO:0007268 61 0.093
guanosine containing compound catabolic process GO:1901069 239 0.091
nervous system development GO:0007399 293 0.090
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.088
gtp catabolic process GO:0006184 237 0.087
regulation of transferase activity GO:0051338 355 0.087
regulation of cell cycle GO:0051726 393 0.086
ion transmembrane transport GO:0034220 338 0.086
hair follicle morphogenesis GO:0031069 2 0.086
small gtpase mediated signal transduction GO:0007264 78 0.078
purine nucleoside catabolic process GO:0006152 398 0.075
cell development GO:0048468 328 0.074
Fly
purine ribonucleoside catabolic process GO:0046130 398 0.074
neurogenesis GO:0022008 169 0.074
Fly
positive regulation of catabolic process GO:0009896 310 0.073
female gamete generation GO:0007292 2 0.066
Fly
regulation of gtpase activity GO:0043087 180 0.066
neuromuscular junction development GO:0007528 3 0.066
generation of neurons GO:0048699 152 0.065
Fly
neuron projection development GO:0031175 106 0.065
Fly
ribonucleotide catabolic process GO:0009261 405 0.065
purine ribonucleotide catabolic process GO:0009154 404 0.064
positive regulation of nucleotide catabolic process GO:0030813 185 0.064
guanosine containing compound metabolic process GO:1901068 244 0.063
regulation of nucleotide catabolic process GO:0030811 205 0.062
cell projection organization GO:0030030 252 0.060
Fly
cation transport GO:0006812 331 0.060
Human
purine containing compound catabolic process GO:0072523 411 0.059
negative regulation of programmed cell death GO:0043069 321 0.059
purine nucleotide catabolic process GO:0006195 405 0.057
organophosphate catabolic process GO:0046434 430 0.057
secretion by cell GO:0032940 226 0.057
cell division GO:0051301 168 0.056
monovalent inorganic cation transport GO:0015672 128 0.056
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.055
vesicle mediated transport GO:0016192 371 0.054
regulation of protein kinase activity GO:0045859 289 0.051
purine nucleoside triphosphate metabolic process GO:0009144 412 0.051
regulation of membrane potential GO:0042391 95 0.051
Human
mitotic cell cycle process GO:1903047 286 0.051
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.050
associative learning GO:0008306 1 0.050
regulation of cellular ketone metabolic process GO:0010565 50 0.050
purine ribonucleoside metabolic process GO:0046128 437 0.049
cellular macromolecular complex assembly GO:0034622 324 0.048
Fly
ribonucleoside catabolic process GO:0042454 406 0.048
cellular amino acid metabolic process GO:0006520 116 0.047
regulation of ion transport GO:0043269 189 0.047
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.046
oogenesis GO:0048477 2 0.046
Fly
mitotic cell cycle GO:0000278 326 0.046
membrane organization GO:0061024 292 0.045
Human
actin filament based process GO:0030029 224 0.045
cellular ketone metabolic process GO:0042180 80 0.044
response to cytokine GO:0034097 232 0.044
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.044
cell projection morphogenesis GO:0048858 129 0.044
Fly
ras protein signal transduction GO:0007265 73 0.043
nucleoside catabolic process GO:0009164 408 0.042
system process GO:0003008 349 0.041
regulation of nucleotide metabolic process GO:0006140 269 0.040
regulation of mapk cascade GO:0043408 262 0.040
cellular amine metabolic process GO:0044106 41 0.040
regulation of purine nucleotide catabolic process GO:0033121 205 0.039
regulation of synaptic plasticity GO:0048167 3 0.039
cellular macromolecule catabolic process GO:0044265 380 0.039
positive regulation of gtpase activity GO:0043547 166 0.038
glycosyl compound catabolic process GO:1901658 413 0.037
positive regulation of synaptic transmission GO:0050806 4 0.037
oocyte differentiation GO:0009994 2 0.036
Fly
positive regulation of gtp catabolic process GO:0033126 166 0.036
regulation of gtp catabolic process GO:0033124 180 0.036
neuron development GO:0048666 113 0.036
Fly
positive regulation of hydrolase activity GO:0051345 331 0.035
signal transduction by phosphorylation GO:0023014 297 0.035
behavior GO:0007610 112 0.035
Fly
stem cell division GO:0017145 2 0.035
positive regulation of nucleotide metabolic process GO:0045981 230 0.035
posttranscriptional regulation of gene expression GO:0010608 213 0.034
cell part morphogenesis GO:0032990 137 0.034
Fly
mrna metabolic process GO:0016071 175 0.034
cell morphogenesis GO:0000902 296 0.034
Fly
central nervous system development GO:0007417 123 0.033
regulation of kinase activity GO:0043549 314 0.033
gtp metabolic process GO:0046039 239 0.033
amine metabolic process GO:0009308 44 0.033
regulation of cell cycle process GO:0010564 266 0.032
negative regulation of phosphate metabolic process GO:0045936 267 0.032
visual learning GO:0008542 1 0.032
cellular component morphogenesis GO:0032989 314 0.032
Fly
ion homeostasis GO:0050801 230 0.032
nucleoside triphosphate metabolic process GO:0009141 422 0.032
cell adhesion GO:0007155 325 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
positive regulation of cell differentiation GO:0045597 211 0.031
negative regulation of protein metabolic process GO:0051248 391 0.031
multicellular organismal aging GO:0010259 3 0.031
positive regulation of cellular catabolic process GO:0031331 284 0.031
positive regulation of nucleoside metabolic process GO:0045979 186 0.031
cytoplasmic transport GO:0016482 379 0.031
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.031
regulation of small gtpase mediated signal transduction GO:0051056 156 0.031
startle response GO:0001964 3 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
lipid metabolic process GO:0006629 381 0.030
cell morphogenesis involved in differentiation GO:0000904 144 0.030
Fly
secretion GO:0046903 254 0.030
response to abiotic stimulus GO:0009628 336 0.030
purine nucleoside triphosphate catabolic process GO:0009146 392 0.029
cellular response to dna damage stimulus GO:0006974 379 0.029
rna processing GO:0006396 255 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.029
Fly
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
negative regulation of protein modification process GO:0031400 200 0.028
positive regulation of programmed cell death GO:0043068 249 0.028
cellular response to growth factor stimulus GO:0071363 197 0.027
cytokinesis GO:0000910 96 0.027
chromatin organization GO:0006325 351 0.027
growth GO:0040007 202 0.026
visual behavior GO:0007632 2 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.026
neuron projection morphogenesis GO:0048812 50 0.026
Fly
organonitrogen compound biosynthetic process GO:1901566 200 0.026
cell cycle phase transition GO:0044770 173 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
cation transmembrane transport GO:0098655 238 0.025
negative regulation of ion transport GO:0043271 39 0.025
negative regulation of cellular component organization GO:0051129 235 0.025
inorganic ion transmembrane transport GO:0098660 231 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
positive regulation of ras gtpase activity GO:0032320 117 0.025
positive regulation of cell death GO:0010942 263 0.024
endomembrane system organization GO:0010256 196 0.024
Human
neuroblast proliferation GO:0007405 4 0.024
response to radiation GO:0009314 151 0.023
neuron differentiation GO:0030182 138 0.023
Fly
cell cell signaling GO:0007267 155 0.023
positive regulation of kinase activity GO:0033674 204 0.023
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
cellular ion homeostasis GO:0006873 168 0.023
protein catabolic process GO:0030163 325 0.023
cation homeostasis GO:0055080 189 0.023
biological adhesion GO:0022610 331 0.022
chemical homeostasis GO:0048878 306 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
negative regulation of acetylcholine gated cation channel activity GO:1903049 1 0.022
endosomal transport GO:0016197 129 0.022
organophosphate biosynthetic process GO:0090407 163 0.022
regulation of secretion GO:0051046 194 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
glutamate receptor signaling pathway GO:0007215 23 0.022
chromatin modification GO:0016568 298 0.022
positive regulation of cell cycle GO:0045787 140 0.022
regulation of neurogenesis GO:0050767 82 0.021
regulation of protein serine threonine kinase activity GO:0071900 179 0.021
synaptic transmission cholinergic GO:0007271 2 0.021
protein oligomerization GO:0051259 173 0.021
regulation of cell development GO:0060284 161 0.021
Fly
sensory perception of pain GO:0019233 4 0.021
mapk cascade GO:0000165 288 0.021
negative regulation of cell death GO:0060548 345 0.021
regulation of secretion by cell GO:1903530 177 0.021
cytokine production GO:0001816 247 0.021
sodium ion transmembrane transport GO:0035725 59 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
regeneration GO:0031099 4 0.021
regulation of ras gtpase activity GO:0032318 128 0.021
hindbrain development GO:0030902 3 0.020
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.020
regulation of cell differentiation GO:0045595 393 0.020
Fly
regulation of cell projection organization GO:0031344 107 0.019
establishment of organelle localization GO:0051656 59 0.019
Fly
camp biosynthetic process GO:0006171 47 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
regulation of cellular component movement GO:0051270 334 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
neurological system process GO:0050877 163 0.019
divalent inorganic cation transport GO:0072511 158 0.019
response to wounding GO:0009611 168 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
cellular divalent inorganic cation homeostasis GO:0072503 128 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
spermatid development GO:0007286 4 0.018
regulation of response to external stimulus GO:0032101 222 0.018
regulation of protein localization GO:0032880 296 0.018
Human
brain development GO:0007420 97 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
positive regulation of phosphorylation GO:0042327 394 0.017
regulation of cell division GO:0051302 116 0.017
positive regulation of developmental process GO:0051094 314 0.017
positive regulation of cell cycle process GO:0090068 106 0.017
rna splicing GO:0008380 131 0.017
positive regulation of mapk cascade GO:0043410 190 0.017
regulation of nervous system development GO:0051960 88 0.017
inorganic cation transmembrane transport GO:0098662 194 0.017
cellular protein catabolic process GO:0044257 261 0.017
cellular response to nitrogen compound GO:1901699 144 0.017
actin cytoskeleton organization GO:0030036 207 0.017
sodium ion transport GO:0006814 61 0.017
histone modification GO:0016570 251 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
spermatid differentiation GO:0048515 4 0.016
positive regulation of transferase activity GO:0051347 227 0.016
glycerophospholipid metabolic process GO:0006650 84 0.016
regulation of locomotion GO:0040012 329 0.016
oocyte development GO:0048599 1 0.016
Fly
head development GO:0060322 108 0.016
negative regulation of transferase activity GO:0051348 124 0.016
detection of stimulus GO:0051606 85 0.016
regulation of cell migration GO:0030334 289 0.016
regulation of cell motility GO:2000145 299 0.016
response to light stimulus GO:0009416 87 0.016
regulation of protein catabolic process GO:0042176 155 0.016
single organism membrane organization GO:0044802 268 0.016
Human
cellular chemical homeostasis GO:0055082 180 0.016
divalent inorganic cation homeostasis GO:0072507 136 0.016
sensory perception of taste GO:0050909 36 0.015
limbic system development GO:0021761 3 0.015
neuronal action potential GO:0019228 9 0.015
actin filament organization GO:0007015 128 0.015
phosphatidylinositol metabolic process GO:0046488 53 0.015
response to oxygen containing compound GO:1901700 369 0.015
metencephalon development GO:0022037 2 0.015
cell projection assembly GO:0030031 126 0.015
cellular calcium ion homeostasis GO:0006874 117 0.015
response to toxic substance GO:0009636 37 0.015
regulation of neuron death GO:1901214 56 0.015
peptidyl tyrosine modification GO:0018212 170 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
innate immune response GO:0045087 178 0.015
neuron projection regeneration GO:0031102 1 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
reproductive process GO:0022414 106 0.014
Fly
g1 s transition of mitotic cell cycle GO:0000082 78 0.014
serotonin transport GO:0006837 3 0.014
cellular response to organic cyclic compound GO:0071407 127 0.014
dephosphorylation GO:0016311 209 0.014
defense response GO:0006952 315 0.014
regulation of cell growth GO:0001558 135 0.014
response to growth factor GO:0070848 205 0.014
regulation of neuroblast proliferation GO:1902692 3 0.014
glycerolipid metabolic process GO:0046486 107 0.014
regulation of cytokinesis GO:0032465 45 0.013
regulation of dna metabolic process GO:0051052 153 0.013
axon cargo transport GO:0008088 2 0.013
Fly
exocytosis GO:0006887 71 0.013
regulation of map kinase activity GO:0043405 108 0.013
regulation of actin filament based process GO:0032970 141 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
microtubule based movement GO:0007018 32 0.013
Fly
angiogenesis GO:0001525 147 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
response to axon injury GO:0048678 1 0.013
transmission of nerve impulse GO:0019226 11 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
neuron death GO:0070997 65 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
circulatory system process GO:0003013 113 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
regulation of protein transport GO:0051223 213 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
taxis GO:0042330 157 0.013
Fly
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
chemotaxis GO:0006935 157 0.013
Fly
synaptic transmission involved in micturition GO:0060084 2 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.012
protein ubiquitination GO:0016567 314 0.012
nucleotide biosynthetic process GO:0009165 109 0.012
mitotic nuclear division GO:0007067 119 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
cognition GO:0050890 43 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
endocytosis GO:0006897 159 0.012
dna repair GO:0006281 198 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
cell activation GO:0001775 213 0.012
single organism cellular localization GO:1902580 332 0.012
Human Fly
regulation of cell morphogenesis GO:0022604 153 0.012
forebrain neuron differentiation GO:0021879 3 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
nitrogen compound transport GO:0071705 191 0.012
tissue migration GO:0090130 119 0.012
sensory perception of chemical stimulus GO:0007606 38 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
organelle fission GO:0048285 149 0.012
regulation of cell activation GO:0050865 125 0.012
positive regulation of neuroblast proliferation GO:0002052 2 0.011
camp metabolic process GO:0046058 61 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
regulation of short term neuronal synaptic plasticity GO:0048172 1 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
regulation of neuron projection development GO:0010975 57 0.011
axon development GO:0061564 34 0.011
Fly
regulation of protein stability GO:0031647 87 0.011
regulation of growth GO:0040008 165 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
lipid biosynthetic process GO:0008610 177 0.011
ossification GO:0001503 121 0.011
protein modification by small protein conjugation GO:0032446 342 0.011
negative regulation of developmental process GO:0051093 247 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
cardiac muscle contraction GO:0060048 34 0.011
regulation of leukocyte chemotaxis GO:0002688 46 0.011
anatomical structure homeostasis GO:0060249 100 0.011
negative regulation of kinase activity GO:0033673 106 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
regulation of neuron differentiation GO:0045664 70 0.011
ribonucleoprotein complex assembly GO:0022618 78 0.011
regulation of acetylcholine gated cation channel activity GO:1903048 1 0.011
regulation of protein binding GO:0043393 66 0.011
determination of adult lifespan GO:0008340 2 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
regulation of binding GO:0051098 111 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
semaphorin plexin signaling pathway GO:0071526 4 0.011
organelle localization GO:0051640 84 0.011
Fly
epidermis morphogenesis GO:0048730 3 0.011
signal transduction by p53 class mediator GO:0072331 72 0.011
protein localization to organelle GO:0033365 280 0.011
phospholipid metabolic process GO:0006644 99 0.011
axonogenesis GO:0007409 31 0.011
Fly
epithelium migration GO:0090132 119 0.011
maintenance of location GO:0051235 112 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
cell junction assembly GO:0034329 67 0.010
carbohydrate metabolic process GO:0005975 207 0.010
protein localization to membrane GO:0072657 160 0.010
Human
regulation of body fluid levels GO:0050878 99 0.010
cell growth GO:0016049 160 0.010
negative regulation of response to external stimulus GO:0032102 83 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010
regulation of proteolysis GO:0030162 293 0.010
cyclic nucleotide biosynthetic process GO:0009190 61 0.010
regulation of system process GO:0044057 101 0.010
cell type specific apoptotic process GO:0097285 125 0.010
sensory perception GO:0007600 103 0.010
response to oxygen levels GO:0070482 100 0.010
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.010
glycerolipid biosynthetic process GO:0045017 51 0.010
calcium ion transport GO:0006816 147 0.010
regulation of endopeptidase activity GO:0052548 170 0.010
positive regulation of cell division GO:0051781 59 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010

KIF5A disease predictions

Disease DO term ID Size Probability Func Analog Org
heart conduction disease DOID:10273 18 0.117
brugada syndrome DOID:0050451 8 0.117
cardiovascular system disease DOID:1287 106 0.117
central nervous system disease DOID:331 186 0.083
nervous system disease DOID:863 431 0.083
disease of mental health DOID:150 70 0.012
epilepsy syndrome DOID:1826 41 0.012
brain disease DOID:936 73 0.012
neurodegenerative disease DOID:1289 102 0.011
paraplegia DOID:607 19 0.002
hereditary spastic paraplegia DOID:2476 19 0.001