Homo sapiens

0 known processes

IARS2

isoleucyl-tRNA synthetase 2, mitochondrial

(Aliases: ILERS,FLJ10326)

IARS2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.478
atp metabolic process GO:0046034 176 0.393
lipid metabolic process GO:0006629 381 0.371
ribonucleoside triphosphate metabolic process GO:0009199 412 0.367
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.356
oxidation reduction process GO:0055114 396 0.348
nucleoside catabolic process GO:0009164 408 0.322
ribonucleoside monophosphate metabolic process GO:0009161 187 0.320
nucleoside monophosphate metabolic process GO:0009123 191 0.310
purine nucleoside triphosphate metabolic process GO:0009144 412 0.267
purine nucleoside monophosphate metabolic process GO:0009126 186 0.257
purine nucleoside triphosphate catabolic process GO:0009146 392 0.221
purine ribonucleoside metabolic process GO:0046128 437 0.194
purine ribonucleoside catabolic process GO:0046130 398 0.171
ribonucleoside triphosphate catabolic process GO:0009203 391 0.149
glycosyl compound catabolic process GO:1901658 413 0.146
nucleoside triphosphate catabolic process GO:0009143 394 0.129
purine containing compound catabolic process GO:0072523 411 0.122
purine nucleoside monophosphate catabolic process GO:0009128 158 0.117
ribonucleoside catabolic process GO:0042454 406 0.113
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.100
post embryonic development GO:0009791 2 0.099
purine nucleotide catabolic process GO:0006195 405 0.087
membrane organization GO:0061024 292 0.082
positive regulation of proteolysis GO:0045862 142 0.081
ribonucleotide catabolic process GO:0009261 405 0.077
mitochondrial membrane organization GO:0007006 40 0.077
positive regulation of hydrolase activity GO:0051345 331 0.076
sulfur compound metabolic process GO:0006790 101 0.073
nucleoside monophosphate catabolic process GO:0009125 159 0.073
apoptotic mitochondrial changes GO:0008637 57 0.069
carbohydrate derivative biosynthetic process GO:1901137 207 0.069
monocarboxylic acid metabolic process GO:0032787 185 0.065
mitochondrial transport GO:0006839 60 0.065
inorganic ion transmembrane transport GO:0098660 231 0.064
cellular lipid metabolic process GO:0044255 303 0.063
ribonucleotide biosynthetic process GO:0009260 81 0.060
fatty acid metabolic process GO:0006631 115 0.060
cellular amino acid metabolic process GO:0006520 116 0.059
oogenesis GO:0048477 2 0.057
vesicle mediated transport GO:0016192 371 0.056
Worm
nucleotide catabolic process GO:0009166 408 0.055
establishment of protein localization to organelle GO:0072594 172 0.053
organophosphate catabolic process GO:0046434 430 0.052
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.052
wound healing GO:0042060 115 0.051
positive regulation of catabolic process GO:0009896 310 0.051
regulation of membrane potential GO:0042391 95 0.050
nucleoside phosphate catabolic process GO:1901292 412 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
cellular modified amino acid metabolic process GO:0006575 64 0.044
transmembrane transport GO:0055085 399 0.043
multicellular organismal aging GO:0010259 3 0.042
cellular ketone metabolic process GO:0042180 80 0.042
nucleoside triphosphate metabolic process GO:0009141 422 0.041
single organism membrane organization GO:0044802 268 0.040
microtubule based process GO:0007017 210 0.040
regulation of peptidase activity GO:0052547 180 0.039
ion transmembrane transport GO:0034220 338 0.038
response to other organism GO:0051707 261 0.038
positive regulation of cellular catabolic process GO:0031331 284 0.037
protein targeting GO:0006605 187 0.037
lipid biosynthetic process GO:0008610 177 0.036
ribonucleoside monophosphate catabolic process GO:0009158 158 0.035
positive regulation of peptidase activity GO:0010952 88 0.034
endocytosis GO:0006897 159 0.034
Worm
embryo development GO:0009790 123 0.034
Worm
cytoplasmic transport GO:0016482 379 0.033
determination of adult lifespan GO:0008340 2 0.033
ras protein signal transduction GO:0007265 73 0.033
regulation of endopeptidase activity GO:0052548 170 0.033
protein processing GO:0016485 226 0.032
amino acid activation GO:0043038 12 0.032
response to wounding GO:0009611 168 0.031
metal ion transport GO:0030001 272 0.031
system process GO:0003008 349 0.031
cellular macromolecular complex assembly GO:0034622 324 0.029
spermatid differentiation GO:0048515 4 0.029
atp catabolic process GO:0006200 157 0.028
defense response GO:0006952 315 0.028
negative regulation of apoptotic process GO:0043066 316 0.028
small gtpase mediated signal transduction GO:0007264 78 0.028
regulation of proteolysis GO:0030162 293 0.027
acetyl coa biosynthetic process from pyruvate GO:0006086 4 0.027
negative regulation of programmed cell death GO:0043069 321 0.026
purine nucleoside catabolic process GO:0006152 398 0.026
purine ribonucleotide catabolic process GO:0009154 404 0.025
mitotic spindle elongation GO:0000022 4 0.024
cation transmembrane transport GO:0098655 238 0.024
sleep GO:0030431 2 0.024
inorganic cation transmembrane transport GO:0098662 194 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
cellular protein complex assembly GO:0043623 188 0.023
cellular metal ion homeostasis GO:0006875 146 0.022
innate immune response GO:0045087 178 0.022
anatomical structure homeostasis GO:0060249 100 0.022
response to drug GO:0042493 81 0.022
ribose phosphate biosynthetic process GO:0046390 82 0.022
cell activation GO:0001775 213 0.022
tissue regeneration GO:0042246 3 0.021
covalent chromatin modification GO:0016569 254 0.021
cellular amide metabolic process GO:0043603 69 0.021
purine nucleotide biosynthetic process GO:0006164 84 0.021
sulfur compound biosynthetic process GO:0044272 38 0.021
immune response GO:0006955 307 0.021
response to endoplasmic reticulum stress GO:0034976 49 0.021
monovalent inorganic cation transport GO:0015672 128 0.021
neuromuscular junction development GO:0007528 3 0.021
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.021
organelle fusion GO:0048284 36 0.020
single organism cell adhesion GO:0098602 179 0.020
cation homeostasis GO:0055080 189 0.020
female gamete generation GO:0007292 2 0.020
ion homeostasis GO:0050801 230 0.020
oocyte development GO:0048599 1 0.020
behavior GO:0007610 112 0.020
tissue homeostasis GO:0001894 63 0.020
regulation of lipid metabolic process GO:0019216 96 0.020
peripheral nervous system development GO:0007422 2 0.019
cofactor metabolic process GO:0051186 87 0.019
hemostasis GO:0007599 76 0.019
neuron projection development GO:0031175 106 0.019
cell morphogenesis GO:0000902 296 0.019
response to external biotic stimulus GO:0043207 261 0.018
response to biotic stimulus GO:0009607 276 0.018
cell adhesion GO:0007155 325 0.018
anterior posterior axis specification GO:0009948 2 0.018
lipid localization GO:0010876 106 0.018
mitochondrion organization GO:0007005 156 0.018
regeneration GO:0031099 4 0.018
guanosine containing compound metabolic process GO:1901068 244 0.017
dicarboxylic acid metabolic process GO:0043648 29 0.017
digestive tract development GO:0048565 75 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
cellular cation homeostasis GO:0030003 163 0.016
oocyte differentiation GO:0009994 2 0.016
glycerolipid metabolic process GO:0046486 107 0.016
cellular component morphogenesis GO:0032989 314 0.016
single organism cellular localization GO:1902580 332 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
associative learning GO:0008306 1 0.016
protein localization to mitochondrion GO:0070585 25 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
purine ribonucleotide biosynthetic process GO:0009152 79 0.016
actin filament based movement GO:0030048 17 0.016
regulation of protein catabolic process GO:0042176 155 0.016
regulation of multi organism process GO:0043900 157 0.015
cell cell signaling GO:0007267 155 0.015
cell projection morphogenesis GO:0048858 129 0.015
regulation of mitochondrion organization GO:0010821 54 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
establishment of organelle localization GO:0051656 59 0.015
regulation of mitochondrial membrane potential GO:0051881 23 0.015
regulation of cytokine production GO:0001817 232 0.015
secretion by cell GO:0032940 226 0.015
response to bacterium GO:0009617 144 0.015
cellular ion homeostasis GO:0006873 168 0.014
cell part morphogenesis GO:0032990 137 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.014
cardiac muscle contraction GO:0060048 34 0.014
positive regulation of cytokine production GO:0001819 167 0.014
protein oligomerization GO:0051259 173 0.014
single organismal cell cell adhesion GO:0016337 148 0.014
zymogen activation GO:0031638 70 0.014
spermatid development GO:0007286 4 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
regulation of response to external stimulus GO:0032101 222 0.013
membrane fusion GO:0061025 43 0.013
tube development GO:0035295 125 0.013
blastoderm segmentation GO:0007350 2 0.013
regulation of cell cycle GO:0051726 393 0.013
mitotic cell cycle GO:0000278 326 0.013
protein localization to organelle GO:0033365 280 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
peptidyl serine modification GO:0018209 106 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
chaperone mediated protein folding GO:0061077 13 0.013
cellular chemical homeostasis GO:0055082 180 0.013
response to lipid GO:0033993 206 0.013
growth GO:0040007 202 0.012
endomembrane system organization GO:0010256 196 0.012
chemical homeostasis GO:0048878 306 0.012
intracellular protein transport GO:0006886 270 0.012
brain morphogenesis GO:0048854 1 0.012
small molecule biosynthetic process GO:0044283 157 0.012
receptor mediated endocytosis GO:0006898 84 0.012
Worm
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.012
fatty acid derivative biosynthetic process GO:1901570 18 0.012
adult locomotory behavior GO:0008344 1 0.012
actin filament based process GO:0030029 224 0.012
peptide metabolic process GO:0006518 51 0.012
protein targeting to mitochondrion GO:0006626 19 0.012
cell projection organization GO:0030030 252 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
Worm
amine metabolic process GO:0009308 44 0.012
locomotory behavior GO:0007626 1 0.012
reproduction GO:0000003 63 0.012
Worm
segmentation GO:0035282 4 0.012
nucleoside phosphate biosynthetic process GO:1901293 109 0.012
gtp metabolic process GO:0046039 239 0.011
organelle localization GO:0051640 84 0.011
establishment of protein localization to mitochondrion GO:0072655 22 0.011
cytokine production GO:0001816 247 0.011
cell development GO:0048468 328 0.011
maintenance of location GO:0051235 112 0.011
immune system development GO:0002520 195 0.011
cell type specific apoptotic process GO:0097285 125 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
rna localization GO:0006403 41 0.011
regulation of ion transport GO:0043269 189 0.011
nitrogen compound transport GO:0071705 191 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
metal ion homeostasis GO:0055065 169 0.011
response to inorganic substance GO:0010035 127 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
intracellular mrna localization GO:0008298 1 0.011
reactive oxygen species metabolic process GO:0072593 75 0.010
gtp catabolic process GO:0006184 237 0.010
response to cytokine GO:0034097 232 0.010
proteasomal protein catabolic process GO:0010498 176 0.010
ubiquitin dependent protein catabolic process GO:0006511 206 0.010
protein import GO:0017038 130 0.010
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
secretion GO:0046903 254 0.010

IARS2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.250
nervous system disease DOID:863 431 0.250
disease of metabolism DOID:0014667 295 0.099
amino acid metabolic disorder DOID:9252 50 0.099
inherited metabolic disorder DOID:655 242 0.099
neurodegenerative disease DOID:1289 102 0.044
disease of cellular proliferation DOID:14566 174 0.027
cancer DOID:162 167 0.021
immune system disease DOID:2914 155 0.015
carbohydrate metabolic disorder DOID:2978 55 0.012