Homo sapiens

118 known processes

SIRT7

sirtuin 7

(Aliases: SIR2L7,MGC126840,MGC126842)

SIRT7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.152
cellular macromolecular complex assembly GO:0034622 324 0.091
female gamete generation GO:0007292 2 0.088
mrna metabolic process GO:0016071 175 0.080
membrane organization GO:0061024 292 0.080
rna processing GO:0006396 255 0.080
multicellular organismal aging GO:0010259 3 0.072
determination of adult lifespan GO:0008340 2 0.068
cellular amine metabolic process GO:0044106 41 0.067
segmentation GO:0035282 4 0.066
locomotory behavior GO:0007626 1 0.065
single organism membrane organization GO:0044802 268 0.063
regulation of cellular amino acid metabolic process GO:0006521 6 0.063
glycosyl compound catabolic process GO:1901658 413 0.063
regulation of cell cycle GO:0051726 393 0.063
regulation of cellular amine metabolic process GO:0033238 11 0.060
purine ribonucleotide catabolic process GO:0009154 404 0.057
endomembrane system organization GO:0010256 196 0.057
regulation of neural precursor cell proliferation GO:2000177 4 0.056
cellular ketone metabolic process GO:0042180 80 0.055
spermatid differentiation GO:0048515 4 0.055
regulation of cellular ketone metabolic process GO:0010565 50 0.053
cellular protein complex assembly GO:0043623 188 0.051
spermatid development GO:0007286 4 0.051
vesicle mediated transport GO:0016192 371 0.050
nucleoside triphosphate metabolic process GO:0009141 422 0.049
cellular amino acid metabolic process GO:0006520 116 0.049
actin cytoskeleton organization GO:0030036 207 0.046
purine containing compound catabolic process GO:0072523 411 0.046
cellular macromolecule catabolic process GO:0044265 380 0.046
ribonucleoprotein complex biogenesis GO:0022613 116 0.045
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.045
ribonucleoside triphosphate metabolic process GO:0009199 412 0.044
mitotic cell cycle process GO:1903047 286 0.044
purine ribonucleoside metabolic process GO:0046128 437 0.044
positive regulation of neural precursor cell proliferation GO:2000179 2 0.044
single organism cellular localization GO:1902580 332 0.043
cytoplasmic transport GO:0016482 379 0.042
positive regulation of catabolic process GO:0009896 310 0.041
purine nucleoside catabolic process GO:0006152 398 0.041
rna catabolic process GO:0006401 71 0.040
amine metabolic process GO:0009308 44 0.040
nucleoside triphosphate catabolic process GO:0009143 394 0.039
actin filament based process GO:0030029 224 0.039
dna repair GO:0006281 198 0.039
Human
blastoderm segmentation GO:0007350 2 0.038
protein modification by small protein conjugation GO:0032446 342 0.038
organophosphate catabolic process GO:0046434 430 0.036
negative regulation of phosphate metabolic process GO:0045936 267 0.035
purine nucleotide catabolic process GO:0006195 405 0.035
ribonucleotide catabolic process GO:0009261 405 0.035
nucleoside catabolic process GO:0009164 408 0.034
negative regulation of phosphorus metabolic process GO:0010563 267 0.034
regulation of transferase activity GO:0051338 355 0.034
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.033
mitotic cell cycle GO:0000278 326 0.033
protein complex disassembly GO:0043241 52 0.033
positive regulation of cell death GO:0010942 263 0.033
protein localization to membrane GO:0072657 160 0.032
secretion by cell GO:0032940 226 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
anatomical structure formation involved in morphogenesis GO:0048646 284 0.032
nervous system development GO:0007399 293 0.031
positive regulation of cellular amine metabolic process GO:0033240 7 0.031
anterior posterior axis specification GO:0009948 2 0.031
negative regulation of cellular amine metabolic process GO:0033239 3 0.031
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.030
positive regulation of transport GO:0051050 336 0.030
intracellular mrna localization GO:0008298 1 0.030
organelle fission GO:0048285 149 0.030
purine ribonucleoside catabolic process GO:0046130 398 0.030
ribonucleoside triphosphate catabolic process GO:0009203 391 0.030
regulation of kinase activity GO:0043549 314 0.030
endocytosis GO:0006897 159 0.030
organelle assembly GO:0070925 176 0.030
oogenesis GO:0048477 2 0.030
positive regulation of phosphorylation GO:0042327 394 0.029
memory GO:0007613 3 0.029
defense response GO:0006952 315 0.029
ribonucleoside catabolic process GO:0042454 406 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.029
negative regulation of catalytic activity GO:0043086 335 0.028
oocyte development GO:0048599 1 0.028
rna splicing GO:0008380 131 0.028
regulation of cellular component biogenesis GO:0044087 281 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
regeneration GO:0031099 4 0.027
tripartite regional subdivision GO:0007351 2 0.027
golgi vesicle transport GO:0048193 80 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
cellular response to oxygen containing compound GO:1901701 276 0.027
nucleotide catabolic process GO:0009166 408 0.027
regulation of cell cycle process GO:0010564 266 0.027
cellular component morphogenesis GO:0032989 314 0.027
neuromuscular junction development GO:0007528 3 0.027
oocyte differentiation GO:0009994 2 0.026
chemical homeostasis GO:0048878 306 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.026
regulation of protein kinase activity GO:0045859 289 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
secretion GO:0046903 254 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
covalent chromatin modification GO:0016569 254 0.025
cell development GO:0048468 328 0.025
anterior posterior axis specification embryo GO:0008595 2 0.025
response to oxygen containing compound GO:1901700 369 0.025
regulation of mapk cascade GO:0043408 262 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
i kappab kinase nf kappab signaling GO:0007249 166 0.024
nucleoside monophosphate metabolic process GO:0009123 191 0.024
microtubule based process GO:0007017 210 0.024
negative regulation of cellular component organization GO:0051129 235 0.023
protein localization to organelle GO:0033365 280 0.023
cell projection organization GO:0030030 252 0.023
regulation of protein localization GO:0032880 296 0.023
regulation of secretion by cell GO:1903530 177 0.023
atp metabolic process GO:0046034 176 0.023
defense response to other organism GO:0098542 129 0.023
protein processing GO:0016485 226 0.022
response to other organism GO:0051707 261 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.022
macromolecular complex disassembly GO:0032984 60 0.022
mrna catabolic process GO:0006402 56 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
establishment of protein localization to membrane GO:0090150 121 0.022
cellular component disassembly GO:0022411 92 0.022
innate immune response GO:0045087 178 0.022
apoptotic signaling pathway GO:0097190 268 0.022
cell adhesion GO:0007155 325 0.021
negative regulation of phosphorylation GO:0042326 174 0.021
chromatin modification GO:0016568 298 0.021
protein maturation GO:0051604 233 0.021
brain morphogenesis GO:0048854 1 0.021
regulation of synaptic plasticity GO:0048167 3 0.021
regulation of dephosphorylation GO:0035303 96 0.021
regulation of secretion GO:0051046 194 0.021
immune response GO:0006955 307 0.021
regulation of protein transport GO:0051223 213 0.021
regulation of dna metabolic process GO:0051052 153 0.021
Human
ncrna metabolic process GO:0034660 108 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
response to biotic stimulus GO:0009607 276 0.020
regulation of growth GO:0040008 165 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
adult locomotory behavior GO:0008344 1 0.020
ribonucleoside monophosphate metabolic process GO:0009161 187 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
defense response to fungus GO:0050832 4 0.020
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
response to fungus GO:0009620 4 0.020
chromatin organization GO:0006325 351 0.020
response to abiotic stimulus GO:0009628 336 0.020
dephosphorylation GO:0016311 209 0.020
mrna processing GO:0006397 133 0.019
dna conformation change GO:0071103 113 0.019
cell morphogenesis GO:0000902 296 0.019
ribonucleoprotein complex assembly GO:0022618 78 0.019
regulation of response to dna damage stimulus GO:2001020 94 0.019
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
small gtpase mediated signal transduction GO:0007264 78 0.019
gtp catabolic process GO:0006184 237 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.019
lipid metabolic process GO:0006629 381 0.018
modification dependent protein catabolic process GO:0019941 209 0.018
cell division GO:0051301 168 0.018
plasma membrane organization GO:0007009 115 0.018
response to external biotic stimulus GO:0043207 261 0.018
positive regulation of immune system process GO:0002684 283 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
cellular lipid metabolic process GO:0044255 303 0.018
response to nutrient levels GO:0031667 81 0.018
ncrna processing GO:0034470 83 0.018
receptor mediated endocytosis GO:0006898 84 0.018
protein catabolic process GO:0030163 325 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
mapk cascade GO:0000165 288 0.017
epithelial cell differentiation GO:0030855 141 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
negative regulation of cell death GO:0060548 345 0.017
compound eye development GO:0048749 1 0.017
mitotic nuclear division GO:0007067 119 0.017
negative regulation of protein modification process GO:0031400 200 0.017
regulation of locomotion GO:0040012 329 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
histone modification GO:0016570 251 0.016
atp catabolic process GO:0006200 157 0.016
regulation of cell differentiation GO:0045595 393 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
positive regulation of cytokine production GO:0001819 167 0.016
macromolecule methylation GO:0043414 97 0.016
immune system development GO:0002520 195 0.016
positive regulation of organelle organization GO:0010638 195 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
actin filament organization GO:0007015 128 0.016
positive regulation of transferase activity GO:0051347 227 0.016
growth GO:0040007 202 0.016
central nervous system development GO:0007417 123 0.016
regulation of proteolysis GO:0030162 293 0.016
oxidation reduction process GO:0055114 396 0.016
water homeostasis GO:0030104 14 0.016
small molecule biosynthetic process GO:0044283 157 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
peptidyl tyrosine phosphorylation GO:0018108 170 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
autophagy GO:0006914 88 0.015
reproductive process GO:0022414 106 0.015
cilium organization GO:0044782 68 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
rhythmic behavior GO:0007622 2 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
regulation of cell morphogenesis GO:0022604 153 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
Human
positive regulation of cellular component organization GO:0051130 376 0.015
endosomal transport GO:0016197 129 0.015
cell projection assembly GO:0030031 126 0.015
cell fate determination GO:0001709 3 0.015
reactive nitrogen species metabolic process GO:2001057 3 0.015
response to nitrogen compound GO:1901698 184 0.015
nucleoside monophosphate catabolic process GO:0009125 159 0.015
regulation of protein catabolic process GO:0042176 155 0.014
nitrogen compound transport GO:0071705 191 0.014
vesicle organization GO:0016050 62 0.014
neurological system process GO:0050877 163 0.014
metal ion transport GO:0030001 272 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
cell growth GO:0016049 160 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
embryo development GO:0009790 123 0.014
regulation of cytokine production GO:0001817 232 0.014
protein targeting GO:0006605 187 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
epithelium development GO:0060429 227 0.014
regulation of immune response GO:0050776 201 0.014
rho protein signal transduction GO:0007266 26 0.014
maintenance of location GO:0051235 112 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
response to extracellular stimulus GO:0009991 85 0.014
ribonucleoprotein complex subunit organization GO:0071826 81 0.014
negative regulation of organelle organization GO:0010639 126 0.014
cellular protein catabolic process GO:0044257 261 0.014
protein ubiquitination GO:0016567 314 0.014
regulation of meiosis GO:0040020 3 0.014
negative regulation of cell cycle GO:0045786 193 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
cellular response to nutrient levels GO:0031669 69 0.014
regulation of intracellular transport GO:0032386 195 0.014
regulation of cellular response to stress GO:0080135 244 0.014
Human
cellular component assembly involved in morphogenesis GO:0010927 73 0.014
cation transport GO:0006812 331 0.014
regulation of cell growth GO:0001558 135 0.014
regulation of protein maturation GO:1903317 150 0.013
associative learning GO:0008306 1 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
positive regulation of secretion GO:0051047 116 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
regulation of gene expression epigenetic GO:0040029 73 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
protein oligomerization GO:0051259 173 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
cellular response to lipid GO:0071396 127 0.013
intracellular protein transport GO:0006886 270 0.013
myosin filament assembly GO:0031034 2 0.013
cellular protein complex disassembly GO:0043624 36 0.013
single organism reproductive process GO:0044702 98 0.013
regulation of cell motility GO:2000145 299 0.013
rna splicing via transesterification reactions GO:0000375 90 0.013
chromosome segregation GO:0007059 114 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
regulation of meiotic cell cycle GO:0051445 4 0.012
immune response activating signal transduction GO:0002757 90 0.012
meiotic chromosome segregation GO:0045132 4 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
striated muscle myosin thick filament assembly GO:0071688 2 0.012
transmembrane transport GO:0055085 399 0.012
ras protein signal transduction GO:0007265 73 0.012
negative regulation of protein maturation GO:1903318 142 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
cytokine production GO:0001816 247 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
circadian behavior GO:0048512 2 0.012
mating GO:0007618 1 0.012
peripheral nervous system development GO:0007422 2 0.012
behavior GO:0007610 112 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
neuroblast proliferation GO:0007405 4 0.012
protein secretion GO:0009306 98 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
ribonucleoside monophosphate catabolic process GO:0009158 158 0.012
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.012
response to lipid GO:0033993 206 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
hemopoiesis GO:0030097 180 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
cellular response to external stimulus GO:0071496 111 0.012
reproduction GO:0000003 63 0.012
rna interference GO:0016246 4 0.012
neurogenesis GO:0022008 169 0.012
glial cell migration GO:0008347 4 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
dna recombination GO:0006310 77 0.012
Human
positive regulation of innate immune response GO:0045089 79 0.011
biological adhesion GO:0022610 331 0.011
cellular homeostasis GO:0019725 196 0.011
negative regulation of phosphatase activity GO:0010923 61 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
myosin filament organization GO:0031033 2 0.011
actin filament based movement GO:0030048 17 0.011
rna localization GO:0006403 41 0.011
response to starvation GO:0042594 59 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
ion transmembrane transport GO:0034220 338 0.011
response to virus GO:0009615 126 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
negative regulation of transferase activity GO:0051348 124 0.011
interspecies interaction between organisms GO:0044419 156 0.011
viral process GO:0016032 146 0.011
regulation of chromosome organization GO:0033044 103 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
lipid biosynthetic process GO:0008610 177 0.011
hindbrain development GO:0030902 3 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
gtp metabolic process GO:0046039 239 0.011
lymphocyte activation GO:0046649 133 0.011
regulation of protein complex assembly GO:0043254 147 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
negative regulation of protein processing GO:0010955 142 0.011
cardiovascular system development GO:0072358 262 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
response to bacterium GO:0009617 144 0.011
brain development GO:0007420 97 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
response to organonitrogen compound GO:0010243 156 0.011
nuclear division GO:0000280 128 0.011
positive regulation of protein transport GO:0051222 135 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
regulation of lymphocyte activation GO:0051249 103 0.011
regulation of cell division GO:0051302 116 0.011
mitochondrion organization GO:0007005 156 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.011
immune effector process GO:0002252 159 0.011
regulation of leukocyte activation GO:0002694 115 0.011
protein deubiquitination GO:0016579 79 0.011
cell type specific apoptotic process GO:0097285 125 0.011
protein localization to plasma membrane GO:0072659 93 0.011
mammary gland morphogenesis GO:0060443 2 0.011
regulation of response to external stimulus GO:0032101 222 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
cilium morphogenesis GO:0060271 75 0.011
sensory perception GO:0007600 103 0.011
meiosis i GO:0007127 4 0.011
response to organic cyclic compound GO:0014070 204 0.011
head development GO:0060322 108 0.011
positive regulation of immune response GO:0050778 159 0.011
negative regulation of growth GO:0045926 97 0.011
glycoprotein metabolic process GO:0009100 110 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of cellular component movement GO:0051270 334 0.011
receptor metabolic process GO:0043112 81 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.010
protein homooligomerization GO:0051260 100 0.010
negative regulation of transport GO:0051051 176 0.010
regulation of ion transmembrane transport GO:0034765 132 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
regulation of nuclear division GO:0051783 65 0.010
peptidyl tyrosine modification GO:0018212 170 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
regulation of protein processing GO:0070613 150 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.010
organic acid biosynthetic process GO:0016053 97 0.010
startle response GO:0001964 3 0.010
morphogenesis of embryonic epithelium GO:0016331 4 0.010
somitogenesis GO:0001756 2 0.010
positive regulation of synaptic transmission GO:0050806 4 0.010
viral life cycle GO:0019058 132 0.010
mrna splicing via spliceosome GO:0000398 89 0.010
regulation of cell activation GO:0050865 125 0.010
regulation of innate immune response GO:0045088 97 0.010
immune response regulating signaling pathway GO:0002764 97 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
inner ear morphogenesis GO:0042472 4 0.010
synaptic vesicle recycling GO:0036465 3 0.010
response to cytokine GO:0034097 232 0.010
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.010
negative regulation of kinase activity GO:0033673 106 0.010
circulatory system development GO:0072359 262 0.010
divalent inorganic cation transport GO:0072511 158 0.010
regulation of actin filament based process GO:0032970 141 0.010
response to radiation GO:0009314 151 0.010

SIRT7 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.024
disease of metabolism DOID:0014667 295 0.023
inherited metabolic disorder DOID:655 242 0.023
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
organ system cancer DOID:0050686 164 0.022
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015
sensory system disease DOID:0050155 203 0.015
muscular disease DOID:0080000 114 0.014
muscle tissue disease DOID:66 113 0.014
myopathy DOID:423 104 0.013
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012