Homo sapiens

51 known processes

CDK11A

cyclin-dependent kinase 11A

(Aliases: PITSLRE,MGC131975,CDK11-p46,p58GTA,CDC2L2,CDC2L3,CDK11-p110,CDK11-p58)

CDK11A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.334
amine metabolic process GO:0009308 44 0.143
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.126
cellular amine metabolic process GO:0044106 41 0.100
mrna metabolic process GO:0016071 175 0.089
cellular amino acid metabolic process GO:0006520 116 0.078
regulation of cell cycle GO:0051726 393 0.078
Mouse
oogenesis GO:0048477 2 0.076
response to abiotic stimulus GO:0009628 336 0.075
regulation of cell cycle process GO:0010564 266 0.075
Mouse
blastoderm segmentation GO:0007350 2 0.074
oocyte differentiation GO:0009994 2 0.071
regulation of cellular amino acid metabolic process GO:0006521 6 0.062
locomotory behavior GO:0007626 1 0.058
negative regulation of cell death GO:0060548 345 0.058
Mouse
tripartite regional subdivision GO:0007351 2 0.056
cellular ketone metabolic process GO:0042180 80 0.051
actin filament based process GO:0030029 224 0.051
oocyte development GO:0048599 1 0.051
mating GO:0007618 1 0.050
circadian behavior GO:0048512 2 0.050
nervous system development GO:0007399 293 0.050
female gamete generation GO:0007292 2 0.048
covalent chromatin modification GO:0016569 254 0.048
vesicle mediated transport GO:0016192 371 0.048
mrna processing GO:0006397 133 0.048
regulation of mitotic cell cycle GO:0007346 189 0.047
Mouse
rhythmic behavior GO:0007622 2 0.047
regulation of cellular amine metabolic process GO:0033238 11 0.047
protein autophosphorylation GO:0046777 123 0.046
multicellular organismal aging GO:0010259 3 0.046
intracellular protein transport GO:0006886 270 0.043
chromatin modification GO:0016568 298 0.041
anterior posterior axis specification embryo GO:0008595 2 0.041
protein catabolic process GO:0030163 325 0.041
negative regulation of programmed cell death GO:0043069 321 0.040
Mouse
mapk cascade GO:0000165 288 0.040
nuclear transcribed mrna catabolic process exonucleolytic GO:0000291 7 0.039
regulation of mapk cascade GO:0043408 262 0.038
single organism membrane organization GO:0044802 268 0.038
immune response GO:0006955 307 0.038
meiosis i GO:0007127 4 0.038
regulation of meiotic cell cycle GO:0051445 4 0.038
intracellular mrna localization GO:0008298 1 0.037
regulation of growth GO:0040008 165 0.037
compound eye development GO:0048749 1 0.036
cell development GO:0048468 328 0.036
sex determination GO:0007530 3 0.035
cytoplasmic transport GO:0016482 379 0.035
positive regulation of mapk cascade GO:0043410 190 0.033
protein modification by small protein conjugation GO:0032446 342 0.033
positive regulation of phosphorylation GO:0042327 394 0.033
growth GO:0040007 202 0.032
neurogenesis GO:0022008 169 0.032
biological adhesion GO:0022610 331 0.031
Fly
response to cytokine GO:0034097 232 0.031
anterior posterior axis specification GO:0009948 2 0.030
negative regulation of apoptotic process GO:0043066 316 0.030
Mouse
rna splicing GO:0008380 131 0.029
cell adhesion GO:0007155 325 0.029
Fly
regulation of mrna metabolic process GO:1903311 53 0.029
positive regulation of hydrolase activity GO:0051345 331 0.029
cellular macromolecular complex assembly GO:0034622 324 0.029
chromatin organization GO:0006325 351 0.029
dephosphorylation GO:0016311 209 0.028
cellular response to dna damage stimulus GO:0006974 379 0.028
segmentation GO:0035282 4 0.028
defense response GO:0006952 315 0.028
cellular macromolecule catabolic process GO:0044265 380 0.028
cell morphogenesis GO:0000902 296 0.028
Fly
regulation of endopeptidase activity GO:0052548 170 0.027
immune system development GO:0002520 195 0.027
cellular component morphogenesis GO:0032989 314 0.027
Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.027
ribonucleoprotein complex assembly GO:0022618 78 0.027
nucleoside monophosphate catabolic process GO:0009125 159 0.026
positive regulation of transferase activity GO:0051347 227 0.026
regulation of cellular response to stress GO:0080135 244 0.026
positive regulation of protein kinase activity GO:0045860 190 0.026
rna splicing via transesterification reactions GO:0000375 90 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
i kappab kinase nf kappab signaling GO:0007249 166 0.025
hemopoiesis GO:0030097 180 0.025
single organism cellular localization GO:1902580 332 0.025
protein ubiquitination GO:0016567 314 0.025
regulation of cell morphogenesis GO:0022604 153 0.024
Fly
spermatid development GO:0007286 4 0.024
cell projection organization GO:0030030 252 0.024
regulation of wnt signaling pathway GO:0030111 123 0.024
spermatid differentiation GO:0048515 4 0.024
nucleotide catabolic process GO:0009166 408 0.024
ras protein signal transduction GO:0007265 73 0.024
cellular response to endogenous stimulus GO:0071495 336 0.023
regulation of hormone levels GO:0010817 125 0.023
regulation of anatomical structure morphogenesis GO:0022603 286 0.023
Fly
associative learning GO:0008306 1 0.023
regulation of protein catabolic process GO:0042176 155 0.023
regulation of circadian sleep wake cycle GO:0042749 2 0.023
positive regulation of catabolic process GO:0009896 310 0.023
protein localization to membrane GO:0072657 160 0.022
positive regulation of cell death GO:0010942 263 0.022
enzyme linked receptor protein signaling pathway GO:0007167 303 0.022
cellular protein complex assembly GO:0043623 188 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
positive regulation of protein phosphorylation GO:0001934 313 0.022
dna replication GO:0006260 116 0.022
cell fate determination GO:0001709 3 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
protein maturation GO:0051604 233 0.021
regulation of peptidase activity GO:0052547 180 0.021
ribonucleoprotein complex biogenesis GO:0022613 116 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
cell cell signaling GO:0007267 155 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.021
organelle fission GO:0048285 149 0.021
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
histone modification GO:0016570 251 0.021
calcium ion transport GO:0006816 147 0.020
embryo development GO:0009790 123 0.020
Mouse Worm
protein processing GO:0016485 226 0.020
determination of adult lifespan GO:0008340 2 0.020
reproductive process GO:0022414 106 0.020
regulation of cell differentiation GO:0045595 393 0.020
morphogenesis of embryonic epithelium GO:0016331 4 0.020
neural tube formation GO:0001841 3 0.020
membrane organization GO:0061024 292 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
single organism reproductive process GO:0044702 98 0.019
regulation of meiosis GO:0040020 3 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
regeneration GO:0031099 4 0.019
response to nitrogen compound GO:1901698 184 0.019
purine containing compound catabolic process GO:0072523 411 0.019
primary neural tube formation GO:0014020 3 0.019
cation transport GO:0006812 331 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
rna processing GO:0006396 255 0.018
chronological cell aging GO:0001300 2 0.018
dna conformation change GO:0071103 113 0.018
cell division GO:0051301 168 0.018
Mouse
actin cytoskeleton organization GO:0030036 207 0.018
hematopoietic or lymphoid organ development GO:0048534 186 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.018
visual behavior GO:0007632 2 0.018
motor neuron axon guidance GO:0008045 2 0.018
regulation of protein kinase activity GO:0045859 289 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.017
cellular response to nitrogen compound GO:1901699 144 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
mitotic cell cycle process GO:1903047 286 0.017
Mouse
circadian sleep wake cycle process GO:0022410 2 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
regulation of response to external stimulus GO:0032101 222 0.017
metal ion transport GO:0030001 272 0.016
regulation of epithelial cell proliferation GO:0050678 113 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
ribonucleoprotein complex subunit organization GO:0071826 81 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
negative regulation of protein modification process GO:0031400 200 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
peptidyl serine modification GO:0018209 106 0.016
regulation of ion transport GO:0043269 189 0.016
response to radiation GO:0009314 151 0.016
generation of neurons GO:0048699 152 0.016
system process GO:0003008 349 0.016
negative regulation of protein metabolic process GO:0051248 391 0.016
regulation of synaptic plasticity GO:0048167 3 0.016
mrna splicing via spliceosome GO:0000398 89 0.016
cellular component disassembly GO:0022411 92 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
chemotaxis GO:0006935 157 0.015
intracellular receptor signaling pathway GO:0030522 104 0.015
visual learning GO:0008542 1 0.015
neuron development GO:0048666 113 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.015
negative regulation of organelle organization GO:0010639 126 0.015
regulation of rna splicing GO:0043484 62 0.015
cellular lipid metabolic process GO:0044255 303 0.015
nitrogen compound transport GO:0071705 191 0.015
hormone metabolic process GO:0042445 61 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
positive regulation of developmental process GO:0051094 314 0.015
regulation of cell growth GO:0001558 135 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
regulation of cellular component movement GO:0051270 334 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
regulation of immune response GO:0050776 201 0.015
regulation of protein processing GO:0070613 150 0.015
cellular response to cytokine stimulus GO:0071345 181 0.014
cardiovascular system development GO:0072358 262 0.014
cytokine mediated signaling pathway GO:0019221 109 0.014
organelle assembly GO:0070925 176 0.014
ribonucleoside catabolic process GO:0042454 406 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
neural tube closure GO:0001843 3 0.014
serine phosphorylation of stat protein GO:0042501 4 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
regulation of dna metabolic process GO:0051052 153 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
neuromuscular junction development GO:0007528 3 0.014
small molecule catabolic process GO:0044282 92 0.014
regulation of proteolysis GO:0030162 293 0.014
cell part morphogenesis GO:0032990 137 0.014
thymus development GO:0048538 3 0.014
positive regulation of immune system process GO:0002684 283 0.014
circadian sleep wake cycle GO:0042745 2 0.013
peptidyl tyrosine modification GO:0018212 170 0.013
positive regulation of smoothened signaling pathway GO:0045880 4 0.013
nerve development GO:0021675 4 0.013
positive regulation of transport GO:0051050 336 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
developmental process involved in reproduction GO:0003006 66 0.013
wnt signaling pathway GO:0016055 156 0.013
rna localization GO:0006403 41 0.013
response to growth factor GO:0070848 205 0.013
regulation of defense response GO:0031347 154 0.013
divalent metal ion transport GO:0070838 152 0.013
purine ribonucleoside catabolic process GO:0046130 398 0.013
nuclear division GO:0000280 128 0.013
Mouse
stem cell differentiation GO:0048863 93 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
mitotic cell cycle GO:0000278 326 0.013
Mouse Fly
negative regulation of cell cycle GO:0045786 193 0.013
mitotic nuclear division GO:0007067 119 0.013
Mouse
negative regulation of developmental process GO:0051093 247 0.013
t cell differentiation in thymus GO:0033077 4 0.013
atp metabolic process GO:0046034 176 0.013
response to axon injury GO:0048678 1 0.013
autophagy GO:0006914 88 0.013
regulation of dephosphorylation GO:0035303 96 0.012
behavior GO:0007610 112 0.012
regulation of protein maturation GO:1903317 150 0.012
regulation of leukocyte differentiation GO:1902105 61 0.012
sensory perception GO:0007600 103 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
regulation of transferase activity GO:0051338 355 0.012
response to fungus GO:0009620 4 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
dna recombination GO:0006310 77 0.012
tube closure GO:0060606 3 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
reproductive system development GO:0061458 56 0.012
response to light stimulus GO:0009416 87 0.012
response to organonitrogen compound GO:0010243 156 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
cell cycle phase transition GO:0044770 173 0.012
small molecule biosynthetic process GO:0044283 157 0.012
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.012
regulation of cell migration GO:0030334 289 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
response to hyperoxia GO:0055093 4 0.012
regulation of metal ion transport GO:0010959 120 0.012
cell morphogenesis involved in differentiation GO:0000904 144 0.012
regulation of nuclear division GO:0051783 65 0.012
Mouse
regionalization GO:0003002 29 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
multicellular organismal response to stress GO:0033555 1 0.012
ion homeostasis GO:0050801 230 0.012
methylation GO:0032259 106 0.012
organophosphate catabolic process GO:0046434 430 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
defense response to fungus GO:0050832 4 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
regulation of mrna processing GO:0050684 48 0.011
positive regulation of wnt signaling pathway GO:0030177 54 0.011
regulation of phosphatase activity GO:0010921 81 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
peptidyl serine phosphorylation GO:0018105 101 0.011
histone lysine methylation GO:0034968 50 0.011
lymphocyte homeostasis GO:0002260 4 0.011
nucleosome organization GO:0034728 66 0.011
response to oxygen containing compound GO:1901700 369 0.011
lipid metabolic process GO:0006629 381 0.011
cellular homeostasis GO:0019725 196 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
regulation of cell division GO:0051302 116 0.011
Mouse
negative regulation of protein maturation GO:1903318 142 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
nucleoside catabolic process GO:0009164 408 0.011
epithelium migration GO:0090132 119 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
taxis GO:0042330 157 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
memory GO:0007613 3 0.011
response to external biotic stimulus GO:0043207 261 0.010
response to hypoxia GO:0001666 96 0.010
cranial nerve development GO:0021545 4 0.010
response to transforming growth factor beta GO:0071559 94 0.010
neurological system process GO:0050877 163 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
response to decreased oxygen levels GO:0036293 96 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
blood vessel development GO:0001568 172 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
sleep GO:0030431 2 0.010
nuclear transport GO:0051169 179 0.010
cation homeostasis GO:0055080 189 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
regulation of protein serine threonine kinase activity GO:0071900 179 0.010
regulation of cell adhesion GO:0030155 166 0.010
positive regulation of kinase activity GO:0033674 204 0.010
negative regulation of protein processing GO:0010955 142 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010
cellular protein catabolic process GO:0044257 261 0.010
regulation of apoptotic signaling pathway GO:2001233 175 0.010
Mouse
innate immune response GO:0045087 178 0.010
dna packaging GO:0006323 77 0.010

CDK11A disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.040
myopathy DOID:423 104 0.035
muscular disease DOID:0080000 114 0.035
muscle tissue disease DOID:66 113 0.035
disease of cellular proliferation DOID:14566 174 0.024
disease of mental health DOID:150 70 0.023
cardiovascular system disease DOID:1287 106 0.022
cancer DOID:162 167 0.020
organ system cancer DOID:0050686 164 0.020
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020
sensory system disease DOID:0050155 203 0.018
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.018
neurodegenerative disease DOID:1289 102 0.016
connective tissue disease DOID:65 109 0.013
retinal disease DOID:5679 118 0.012