Homo sapiens

0 known processes

VDAC2

voltage-dependent anion channel 2

(Aliases: FLJ23841,POR)

VDAC2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
apoptotic mitochondrial changes GO:0008637 57 0.825
regulation of mitochondrion organization GO:0010821 54 0.740
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.645
apoptotic signaling pathway GO:0097190 268 0.582
Mouse
regulation of peptidase activity GO:0052547 180 0.544
positive regulation of mitochondrion organization GO:0010822 30 0.544
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.542
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.489
protein processing GO:0016485 226 0.483
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.446
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.352
purine nucleoside monophosphate metabolic process GO:0009126 186 0.333
phototransduction GO:0007602 3 0.333
Fly
activation of cysteine type endopeptidase activity GO:0097202 57 0.296
regulation of apoptotic signaling pathway GO:2001233 175 0.292
Mouse
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.288
zymogen activation GO:0031638 70 0.268
ribonucleoside monophosphate metabolic process GO:0009161 187 0.264
release of cytochrome c from mitochondria GO:0001836 35 0.243
positive regulation of apoptotic signaling pathway GO:2001235 70 0.228
response to abiotic stimulus GO:0009628 336 0.225
Fly
cation transport GO:0006812 331 0.206
positive regulation of organelle organization GO:0010638 195 0.205
spermatid development GO:0007286 4 0.201
Fly
regulation of endopeptidase activity GO:0052548 170 0.200
purine ribonucleoside metabolic process GO:0046128 437 0.186
fear response GO:0042596 0 0.183
system process GO:0003008 349 0.176
positive regulation of peptidase activity GO:0010952 88 0.176
chemical homeostasis GO:0048878 306 0.174
positive regulation of apoptotic process GO:0043065 246 0.170
nucleoside triphosphate metabolic process GO:0009141 422 0.164
regulation of cysteine type endopeptidase activity GO:2000116 127 0.164
ion transmembrane transport GO:0034220 338 0.159
Yeast Fly
positive regulation of cellular component organization GO:0051130 376 0.158
post embryonic development GO:0009791 2 0.157
nucleotide catabolic process GO:0009166 408 0.149
protein maturation GO:0051604 233 0.138
neuroblast proliferation GO:0007405 4 0.137
multicellular organismal response to stress GO:0033555 1 0.135
nucleoside monophosphate metabolic process GO:0009123 191 0.135
response to hypoxia GO:0001666 96 0.133
positive regulation of cell death GO:0010942 263 0.133
anion transport GO:0006820 161 0.126
Yeast Fly
response to decreased oxygen levels GO:0036293 96 0.123
positive regulation of programmed cell death GO:0043068 249 0.121
mating GO:0007618 1 0.120
purine nucleoside triphosphate metabolic process GO:0009144 412 0.120
positive regulation of proteolysis GO:0045862 142 0.119
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.115
membrane organization GO:0061024 292 0.113
ribonucleoside triphosphate catabolic process GO:0009203 391 0.109
positive regulation of hydrolase activity GO:0051345 331 0.109
regulation of proteolysis GO:0030162 293 0.101
mitochondrial transport GO:0006839 60 0.099
atp synthesis coupled electron transport GO:0042773 4 0.097
metal ion transport GO:0030001 272 0.092
transmembrane transport GO:0055085 399 0.091
Yeast Zebrafish Fly
regulation of purine nucleotide metabolic process GO:1900542 264 0.090
response to oxygen levels GO:0070482 100 0.090
inorganic cation transmembrane transport GO:0098662 194 0.090
carbohydrate derivative biosynthetic process GO:1901137 207 0.089
purine ribonucleoside catabolic process GO:0046130 398 0.089
organophosphate catabolic process GO:0046434 430 0.088
ribonucleoside triphosphate metabolic process GO:0009199 412 0.087
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.086
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.085
nucleoside phosphate catabolic process GO:1901292 412 0.082
mitochondrion organization GO:0007005 156 0.082
Yeast Fly
cellular response to decreased oxygen levels GO:0036294 51 0.082
multicellular organismal aging GO:0010259 3 0.081
nucleoside triphosphate catabolic process GO:0009143 394 0.079
cellular macromolecule catabolic process GO:0044265 380 0.075
intracellular protein transport GO:0006886 270 0.072
negative regulation of apoptotic process GO:0043066 316 0.071
Mouse
cell type specific apoptotic process GO:0097285 125 0.071
behavioral defense response GO:0002209 0 0.070
spinal cord development GO:0021510 4 0.067
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.064
purine nucleotide catabolic process GO:0006195 405 0.063
negative regulation of programmed cell death GO:0043069 321 0.062
Mouse
regulation of nucleoside metabolic process GO:0009118 209 0.059
negative regulation of cell proliferation GO:0008285 228 0.058
cellular response to hypoxia GO:0071456 51 0.058
cation transmembrane transport GO:0098655 238 0.057
ribonucleotide catabolic process GO:0009261 405 0.056
purine ribonucleotide catabolic process GO:0009154 404 0.052
regulation of oxidative phosphorylation GO:0002082 3 0.052
regulation of ion transport GO:0043269 189 0.051
Yeast Fly
regulation of neural precursor cell proliferation GO:2000177 4 0.047
neuron apoptotic process GO:0051402 39 0.047
cellular metal ion homeostasis GO:0006875 146 0.046
oxidative phosphorylation GO:0006119 10 0.046
regulation of nucleotide metabolic process GO:0006140 269 0.046
cellular response to oxygen levels GO:0071453 55 0.046
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.046
mitochondrial membrane organization GO:0007006 40 0.046
negative regulation of neural precursor cell proliferation GO:2000178 1 0.045
purine containing compound catabolic process GO:0072523 411 0.045
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
epithelium development GO:0060429 227 0.045
Human
neurological system process GO:0050877 163 0.043
cellular chemical homeostasis GO:0055082 180 0.043
purine nucleoside catabolic process GO:0006152 398 0.042
purine nucleoside triphosphate biosynthetic process GO:0009145 11 0.042
cellular ion homeostasis GO:0006873 168 0.042
regeneration GO:0031099 4 0.041
Zebrafish
oxidation reduction process GO:0055114 396 0.041
ion homeostasis GO:0050801 230 0.039
locomotory behavior GO:0007626 1 0.039
regulation of ion transmembrane transport GO:0034765 132 0.039
Yeast Fly
growth GO:0040007 202 0.038
Zebrafish
calcium ion transport GO:0006816 147 0.038
positive regulation of cellular catabolic process GO:0031331 284 0.038
response to radiation GO:0009314 151 0.037
Fly
monovalent inorganic cation transport GO:0015672 128 0.037
response to hormone GO:0009725 175 0.037
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.037
cellular homeostasis GO:0019725 196 0.037
Yeast
spermatid differentiation GO:0048515 4 0.036
Fly
cytoplasmic transport GO:0016482 379 0.035
rna splicing GO:0008380 131 0.035
regulation of transmembrane transport GO:0034762 139 0.035
Yeast Fly
mitotic cell cycle GO:0000278 326 0.034
negative regulation of organelle organization GO:0010639 126 0.034
vesicle mediated transport GO:0016192 371 0.034
generation of precursor metabolites and energy GO:0006091 68 0.034
regulation of mitochondrial membrane permeability GO:0046902 25 0.034
negative regulation of multicellular organismal process GO:0051241 317 0.034
detection of stimulus GO:0051606 85 0.033
Fly
reproductive system development GO:0061458 56 0.033
phosphate ion transport GO:0006817 7 0.033
anatomical structure homeostasis GO:0060249 100 0.033
cellular divalent inorganic cation homeostasis GO:0072503 128 0.033
negative regulation of stem cell proliferation GO:2000647 3 0.032
single organism cellular localization GO:1902580 332 0.032
microtubule based process GO:0007017 210 0.032
regulation of nucleotide catabolic process GO:0030811 205 0.031
nitrogen compound transport GO:0071705 191 0.031
Yeast
nucleoside triphosphate biosynthetic process GO:0009142 20 0.031
regulation of membrane permeability GO:0090559 25 0.031
actin cytoskeleton organization GO:0030036 207 0.031
ribonucleoside catabolic process GO:0042454 406 0.030
embryo development GO:0009790 123 0.030
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.030
amine metabolic process GO:0009308 44 0.030
divalent inorganic cation transport GO:0072511 158 0.029
single organism carbohydrate metabolic process GO:0044723 193 0.029
cellular respiration GO:0045333 21 0.028
neuromuscular junction development GO:0007528 3 0.027
divalent metal ion transport GO:0070838 152 0.027
defense response GO:0006952 315 0.027
protein localization to membrane GO:0072657 160 0.027
regulation of cell development GO:0060284 161 0.027
organic anion transport GO:0015711 103 0.027
regulation of purine nucleotide catabolic process GO:0033121 205 0.026
synaptic transmission GO:0007268 61 0.026
inorganic anion transmembrane transport GO:0098661 47 0.026
cellular cation homeostasis GO:0030003 163 0.026
regulation of growth GO:0040008 165 0.026
positive regulation of developmental process GO:0051094 314 0.026
single organism membrane organization GO:0044802 268 0.026
nucleoside catabolic process GO:0009164 408 0.025
negative regulation of hydrolase activity GO:0051346 182 0.025
divalent inorganic cation homeostasis GO:0072507 136 0.025
organelle assembly GO:0070925 176 0.025
lipid metabolic process GO:0006629 381 0.025
reproductive process GO:0022414 106 0.025
Fly
purine nucleoside monophosphate catabolic process GO:0009128 158 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
detection of abiotic stimulus GO:0009582 15 0.024
Fly
neuron death GO:0070997 65 0.024
glycosyl compound catabolic process GO:1901658 413 0.023
reproduction GO:0000003 63 0.023
Fly
negative regulation of cell differentiation GO:0045596 171 0.023
actin filament based process GO:0030029 224 0.023
mitochondrial calcium ion transport GO:0006851 7 0.023
ribonucleotide biosynthetic process GO:0009260 81 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
regulation of anion transport GO:0044070 25 0.021
Yeast Fly
alcohol metabolic process GO:0006066 114 0.021
positive regulation of catabolic process GO:0009896 310 0.021
protein import GO:0017038 130 0.020
negative regulation of protein metabolic process GO:0051248 391 0.020
positive regulation of immune system process GO:0002684 283 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
determination of adult lifespan GO:0008340 2 0.020
atp catabolic process GO:0006200 157 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
metal ion homeostasis GO:0055065 169 0.019
endomembrane system organization GO:0010256 196 0.019
endocytosis GO:0006897 159 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.019
atp metabolic process GO:0046034 176 0.019
negative regulation of transport GO:0051051 176 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
Fly
inorganic ion transmembrane transport GO:0098660 231 0.018
cellular response to oxygen containing compound GO:1901701 276 0.018
cellular lipid metabolic process GO:0044255 303 0.018
response to drug GO:0042493 81 0.018
regulation of transporter activity GO:0032409 82 0.018
female gamete generation GO:0007292 2 0.018
wound healing GO:0042060 115 0.018
Zebrafish
response to light stimulus GO:0009416 87 0.018
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.018
regulation of kinase activity GO:0043549 314 0.018
ribose phosphate biosynthetic process GO:0046390 82 0.018
aspartate metabolic process GO:0006531 4 0.018
positive regulation of gtpase activity GO:0043547 166 0.017
positive regulation of transport GO:0051050 336 0.017
behavior GO:0007610 112 0.017
mitochondrial calcium ion homeostasis GO:0051560 11 0.017
negative regulation of developmental process GO:0051093 247 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.017
cell cell signaling GO:0007267 155 0.017
cellular response to oxidative stress GO:0034599 85 0.016
gtp metabolic process GO:0046039 239 0.016
response to external biotic stimulus GO:0043207 261 0.016
tissue regeneration GO:0042246 3 0.016
Zebrafish
immune response GO:0006955 307 0.016
response to antibiotic GO:0046677 15 0.016
oogenesis GO:0048477 2 0.016
transition metal ion transport GO:0000041 23 0.016
cation homeostasis GO:0055080 189 0.015
response to wounding GO:0009611 168 0.015
Zebrafish
transition metal ion homeostasis GO:0055076 31 0.015
cell division GO:0051301 168 0.015
biological adhesion GO:0022610 331 0.015
negative regulation of cell death GO:0060548 345 0.015
Mouse
regulation of gtp catabolic process GO:0033124 180 0.015
response to toxic substance GO:0009636 37 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
Mouse
regulation of protein localization GO:0032880 296 0.014
negative regulation of catabolic process GO:0009895 104 0.014
atp biosynthetic process GO:0006754 11 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
Mouse
angiogenesis GO:0001525 147 0.014
cell adhesion GO:0007155 325 0.014
cell development GO:0048468 328 0.014
Fly
ribonucleoside monophosphate catabolic process GO:0009158 158 0.014
negative regulation of epithelial cell migration GO:0010633 38 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
cell differentiation in spinal cord GO:0021515 1 0.014
response to cytokine GO:0034097 232 0.013
glycosyl compound biosynthetic process GO:1901659 27 0.013
small molecule biosynthetic process GO:0044283 157 0.013
dna catabolic process GO:0006308 49 0.013
carbohydrate metabolic process GO:0005975 207 0.013
purine containing compound biosynthetic process GO:0072522 88 0.013
regulation of neuroblast proliferation GO:1902692 3 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.013
Mouse
response to oxygen containing compound GO:1901700 369 0.013
regulation of cellular component movement GO:0051270 334 0.013
regulation of intracellular transport GO:0032386 195 0.013
single organism reproductive process GO:0044702 98 0.013
Fly
establishment of protein localization to membrane GO:0090150 121 0.013
hydrogen transport GO:0006818 23 0.013
protein import into mitochondrial matrix GO:0030150 1 0.013
regulation of cell differentiation GO:0045595 393 0.013
multi organism reproductive process GO:0044703 54 0.012
Fly
vasculature development GO:0001944 181 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
regulation of protein maturation GO:1903317 150 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
energy derivation by oxidation of organic compounds GO:0015980 43 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
cell cycle phase transition GO:0044770 173 0.012
positive regulation of immune response GO:0050778 159 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
negative regulation of mitochondrion organization GO:0010823 22 0.012
central nervous system development GO:0007417 123 0.012
regulation of dna metabolic process GO:0051052 153 0.012
cell growth GO:0016049 160 0.012
regulation of gtpase activity GO:0043087 180 0.012
tripartite regional subdivision GO:0007351 2 0.012
regulation of immune response GO:0050776 201 0.012
organelle fission GO:0048285 149 0.012
epithelial cell differentiation GO:0030855 141 0.012
Human
purine nucleoside monophosphate biosynthetic process GO:0009127 16 0.012
detection of light stimulus GO:0009583 11 0.011
Fly
tube development GO:0035295 125 0.011
mitotic cell cycle process GO:1903047 286 0.011
protein targeting GO:0006605 187 0.011
purine ribonucleotide biosynthetic process GO:0009152 79 0.011
cytokine production GO:0001816 247 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
purine nucleotide biosynthetic process GO:0006164 84 0.011
adult locomotory behavior GO:0008344 1 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
organic acid catabolic process GO:0016054 71 0.011
regulation of protein kinase activity GO:0045859 289 0.011
cellular calcium ion homeostasis GO:0006874 117 0.011
regulation of cellular amino acid metabolic process GO:0006521 6 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
copper ion homeostasis GO:0055070 3 0.011
detection of external stimulus GO:0009581 15 0.011
Fly
innate immune response GO:0045087 178 0.011
peptidyl serine modification GO:0018209 106 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
inorganic anion transport GO:0015698 60 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
guanosine containing compound metabolic process GO:1901068 244 0.010
cellular response to abiotic stimulus GO:0071214 117 0.010
energy coupled proton transport down electrochemical gradient GO:0015985 2 0.010
reproductive structure development GO:0048608 55 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
cellular component morphogenesis GO:0032989 314 0.010
aerobic respiration GO:0009060 7 0.010
organelle localization GO:0051640 84 0.010
phosphate ion transmembrane transport GO:0035435 4 0.010
dicarboxylic acid biosynthetic process GO:0043650 4 0.010
regulation of cell migration GO:0030334 289 0.010
regulation of cell growth GO:0001558 135 0.010

VDAC2 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.045
eye and adnexa disease DOID:1492 150 0.045
nervous system disease DOID:863 431 0.045
cancer DOID:162 167 0.032
disease of cellular proliferation DOID:14566 174 0.032
organ system cancer DOID:0050686 164 0.032
immune system disease DOID:2914 155 0.021
retinal disease DOID:5679 118 0.014
eye disease DOID:5614 149 0.014
hematopoietic system disease DOID:74 100 0.011
retinal degeneration DOID:8466 89 0.011