Homo sapiens

96 known processes

DHX58

DEXH (Asp-Glu-X-His) box polypeptide 58

(Aliases: D11LGP2,D11lgp2e,LGP2)

DHX58 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of viral genome replication GO:0045069 48 0.211
viral life cycle GO:0019058 132 0.186
viral process GO:0016032 146 0.153
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.146
immune response GO:0006955 307 0.125
interspecies interaction between organisms GO:0044419 156 0.125
response to external biotic stimulus GO:0043207 261 0.120
defense response to virus GO:0051607 71 0.115
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.113
response to biotic stimulus GO:0009607 276 0.107
regulation of viral process GO:0050792 103 0.098
cytokine production GO:0001816 247 0.098
response to cytokine GO:0034097 232 0.085
cytoplasmic transport GO:0016482 379 0.084
Human
negative regulation of viral process GO:0048525 66 0.079
positive regulation of cytokine production GO:0001819 167 0.078
multi organism cellular process GO:0044764 156 0.077
glycosylation GO:0070085 71 0.077
nucleoside phosphate biosynthetic process GO:1901293 109 0.077
glycoprotein metabolic process GO:0009100 110 0.076
response to other organism GO:0051707 261 0.073
macromolecule glycosylation GO:0043413 63 0.070
innate immune response GO:0045087 178 0.068
response to virus GO:0009615 126 0.068
cellular macromolecule catabolic process GO:0044265 380 0.068
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.065
cellular macromolecular complex assembly GO:0034622 324 0.061
Human
regulation of multi organism process GO:0043900 157 0.060
positive regulation of transferase activity GO:0051347 227 0.059
negative regulation of multi organism process GO:0043901 92 0.059
protein glycosylation GO:0006486 62 0.054
negative regulation of protein metabolic process GO:0051248 391 0.053
positive regulation of cell death GO:0010942 263 0.053
mapk cascade GO:0000165 288 0.052
glycoprotein biosynthetic process GO:0009101 91 0.051
posttranscriptional regulation of gene expression GO:0010608 213 0.051
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.050
positive regulation of mapk cascade GO:0043410 190 0.049
positive regulation of phosphorylation GO:0042327 394 0.048
regulation of cytokine production GO:0001817 232 0.045
regulation of immune response GO:0050776 201 0.045
negative regulation of viral genome replication GO:0045071 35 0.044
immune effector process GO:0002252 159 0.044
forebrain neuron differentiation GO:0021879 3 0.043
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.043
Human
protein modification by small protein conjugation GO:0032446 342 0.042
Human
regulation of kinase activity GO:0043549 314 0.042
regulation of apoptotic signaling pathway GO:2001233 175 0.042
blastoderm segmentation GO:0007350 2 0.042
single organism cellular localization GO:1902580 332 0.041
Human
regulation of protein kinase activity GO:0045859 289 0.041
rna catabolic process GO:0006401 71 0.041
organophosphate biosynthetic process GO:0090407 163 0.040
protein acylation GO:0043543 138 0.040
signal transduction by phosphorylation GO:0023014 297 0.039
viral genome replication GO:0019079 50 0.039
positive regulation of protein phosphorylation GO:0001934 313 0.038
carbohydrate derivative biosynthetic process GO:1901137 207 0.038
monosaccharide metabolic process GO:0005996 74 0.037
cellular protein complex assembly GO:0043623 188 0.037
regulation of mapk cascade GO:0043408 262 0.037
hematopoietic stem cell differentiation GO:0060218 4 0.037
purine nucleotide biosynthetic process GO:0006164 84 0.036
gene silencing by mirna GO:0035195 23 0.036
Human
mrna metabolic process GO:0016071 175 0.035
lipoprotein metabolic process GO:0042157 42 0.035
immune response activating signal transduction GO:0002757 90 0.034
protein myristoylation GO:0018377 1 0.033
positive regulation of protein kinase activity GO:0045860 190 0.033
protein targeting GO:0006605 187 0.032
Human
lipoprotein biosynthetic process GO:0042158 33 0.031
single organism carbohydrate metabolic process GO:0044723 193 0.031
positive regulation of immune system process GO:0002684 283 0.030
memory GO:0007613 3 0.030
hair follicle morphogenesis GO:0031069 2 0.029
regulation of transferase activity GO:0051338 355 0.029
response to interferon alpha GO:0035455 11 0.029
regulation of anatomical structure morphogenesis GO:0022603 286 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.029
positive regulation of stress activated mapk cascade GO:0032874 60 0.028
regulation of cellular response to stress GO:0080135 244 0.028
defense response GO:0006952 315 0.027
post embryonic development GO:0009791 2 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
cellular amino acid metabolic process GO:0006520 116 0.027
cellular amine metabolic process GO:0044106 41 0.027
epidermis morphogenesis GO:0048730 3 0.027
immune system development GO:0002520 195 0.027
regulation of cellular component biogenesis GO:0044087 281 0.027
regulation of nuclease activity GO:0032069 11 0.026
purine containing compound biosynthetic process GO:0072522 88 0.026
oogenesis GO:0048477 2 0.026
segmentation GO:0035282 4 0.025
activation of immune response GO:0002253 114 0.025
secretion GO:0046903 254 0.025
regulation of cell cycle GO:0051726 393 0.025
nucleotide biosynthetic process GO:0009165 109 0.025
regulation of cellular amine metabolic process GO:0033238 11 0.025
biological adhesion GO:0022610 331 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
stem cell division GO:0017145 2 0.025
positive regulation of immune response GO:0050778 159 0.024
vesicle mediated transport GO:0016192 371 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
ion transmembrane transport GO:0034220 338 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
regulation of defense response to virus GO:0050688 33 0.023
regulation of stress activated mapk cascade GO:0032872 84 0.023
negative regulation of cell death GO:0060548 345 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
cell differentiation in spinal cord GO:0021515 1 0.023
nuclear transport GO:0051169 179 0.022
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.022
regulation of dna metabolic process GO:0051052 153 0.022
chemical homeostasis GO:0048878 306 0.022
transmembrane transport GO:0055085 399 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
hemopoiesis GO:0030097 180 0.022
female gamete generation GO:0007292 2 0.022
negative regulation of protein maturation GO:1903318 142 0.022
peripheral nervous system development GO:0007422 2 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
negative regulation of gliogenesis GO:0014014 3 0.021
secretion by cell GO:0032940 226 0.021
hexose metabolic process GO:0019318 55 0.021
neurological system process GO:0050877 163 0.021
single organism membrane organization GO:0044802 268 0.021
activation of protein kinase activity GO:0032147 90 0.021
carbohydrate metabolic process GO:0005975 207 0.021
regulation of cellular ketone metabolic process GO:0010565 50 0.020
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.020
protein ubiquitination GO:0016567 314 0.020
regeneration GO:0031099 4 0.020
cellular response to cytokine stimulus GO:0071345 181 0.020
microtubule based process GO:0007017 210 0.020
forebrain generation of neurons GO:0021872 3 0.020
nitrogen compound transport GO:0071705 191 0.020
regulation of immune effector process GO:0002697 91 0.020
determination of adult lifespan GO:0008340 2 0.019
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.019
membrane organization GO:0061024 292 0.019
regulation of cell differentiation GO:0045595 393 0.019
amine metabolic process GO:0009308 44 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
negative regulation of protein modification process GO:0031400 200 0.019
regulation of protein complex assembly GO:0043254 147 0.019
regulation of membrane potential GO:0042391 95 0.019
hindlimb morphogenesis GO:0035137 2 0.019
positive regulation of interferon alpha production GO:0032727 11 0.019
Human
regulation of nucleocytoplasmic transport GO:0046822 98 0.019
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
associative learning GO:0008306 1 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
regulation of secretion by cell GO:1903530 177 0.018
translation GO:0006412 132 0.018
mrna processing GO:0006397 133 0.018
lipid metabolic process GO:0006629 381 0.018
response to nitrogen compound GO:1901698 184 0.018
Human
stress activated protein kinase signaling cascade GO:0031098 94 0.018
cellular ketone metabolic process GO:0042180 80 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
ras protein signal transduction GO:0007265 73 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.017
system process GO:0003008 349 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
defense response to other organism GO:0098542 129 0.017
positive regulation of kinase activity GO:0033674 204 0.017
mitotic cell cycle GO:0000278 326 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
regulation of ribonuclease activity GO:0060700 3 0.017
regulation of cell development GO:0060284 161 0.017
ventral spinal cord development GO:0021517 1 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
regulation of proteolysis GO:0030162 293 0.016
dna catabolic process GO:0006308 49 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
glycosyl compound catabolic process GO:1901658 413 0.016
positive regulation of interleukin 13 biosynthetic process GO:0045368 1 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
purine containing compound catabolic process GO:0072523 411 0.016
spermatid differentiation GO:0048515 4 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
glucose metabolic process GO:0006006 45 0.016
anion transport GO:0006820 161 0.016
regulation of intracellular transport GO:0032386 195 0.016
Human
rna processing GO:0006396 255 0.016
Human
multicellular organismal aging GO:0010259 3 0.016
regulation of protein localization GO:0032880 296 0.015
Human
protein maturation GO:0051604 233 0.015
chromatin organization GO:0006325 351 0.015
nerve development GO:0021675 4 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
protein localization to nucleus GO:0034504 136 0.015
Human
negative regulation of hydrolase activity GO:0051346 182 0.015
regulation of cellular component movement GO:0051270 334 0.015
Human
regulation of cell motility GO:2000145 299 0.015
Human
ion homeostasis GO:0050801 230 0.015
regulation of protein localization to nucleus GO:1900180 85 0.015
Human
regulation of response to biotic stimulus GO:0002831 55 0.015
rho protein signal transduction GO:0007266 26 0.015
cell division GO:0051301 168 0.015
oocyte differentiation GO:0009994 2 0.015
cell adhesion GO:0007155 325 0.015
protein deubiquitination GO:0016579 79 0.015
endosomal transport GO:0016197 129 0.015
protein processing GO:0016485 226 0.015
meiotic chromosome segregation GO:0045132 4 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
negative regulation of transport GO:0051051 176 0.015
protein autophosphorylation GO:0046777 123 0.015
cell morphogenesis GO:0000902 296 0.015
positive regulation of transport GO:0051050 336 0.014
Human
cellular component morphogenesis GO:0032989 314 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
protein oligomerization GO:0051259 173 0.014
locomotory behavior GO:0007626 1 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
tripartite regional subdivision GO:0007351 2 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
protein localization to membrane GO:0072657 160 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.014
ribonucleoprotein complex biogenesis GO:0022613 116 0.014
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
regulation of defense response GO:0031347 154 0.014
organelle assembly GO:0070925 176 0.014
vasculature development GO:0001944 181 0.013
neurotransmitter secretion GO:0007269 4 0.013
activation of mapkk activity GO:0000186 18 0.013
regulation of defense response to virus by host GO:0050691 22 0.013
Human
response to dsrna GO:0043331 25 0.013
Human
purine ribonucleoside catabolic process GO:0046130 398 0.013
tissue morphogenesis GO:0048729 96 0.013
pattern recognition receptor signaling pathway GO:0002221 48 0.013
carboxylic acid catabolic process GO:0046395 71 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
metal ion transport GO:0030001 272 0.013
cation homeostasis GO:0055080 189 0.013
cell fate determination GO:0001709 3 0.013
regulation of protein catabolic process GO:0042176 155 0.013
positive regulation of organelle organization GO:0010638 195 0.013
compound eye development GO:0048749 1 0.013
oocyte development GO:0048599 1 0.013
ncrna metabolic process GO:0034660 108 0.013
Human
negative regulation of cell cycle GO:0045786 193 0.013
small molecule biosynthetic process GO:0044283 157 0.013
neural crest cell development GO:0014032 3 0.013
small gtpase mediated signal transduction GO:0007264 78 0.012
dna repair GO:0006281 198 0.012
neuromuscular junction development GO:0007528 3 0.012
protein catabolic process GO:0030163 325 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
regulation of translation GO:0006417 89 0.012
positive regulation of rig i signaling pathway GO:1900246 4 0.012
mitotic cell cycle process GO:1903047 286 0.012
negative regulation of organelle organization GO:0010639 126 0.012
epithelium development GO:0060429 227 0.012
regulation of cell adhesion GO:0030155 166 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
Human
regulation of protein maturation GO:1903317 150 0.012
negative regulation of proteolysis GO:0045861 132 0.012
spermatid development GO:0007286 4 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
muscle cell differentiation GO:0042692 63 0.012
synaptic vesicle recycling GO:0036465 3 0.012
cation transmembrane transport GO:0098655 238 0.012
divalent inorganic cation transport GO:0072511 158 0.011
regulation of mhc class i biosynthetic process GO:0045343 4 0.011
negative regulation of mitochondrial depolarization GO:0051902 2 0.011
cellular ion homeostasis GO:0006873 168 0.011
glucose homeostasis GO:0042593 31 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
positive regulation of catabolic process GO:0009896 310 0.011
apoptotic signaling pathway GO:0097190 268 0.011
anterior posterior axis specification GO:0009948 2 0.011
positive regulation of developmental process GO:0051094 314 0.011
cellular lipid metabolic process GO:0044255 303 0.011
intracellular receptor signaling pathway GO:0030522 104 0.011
regulation of chemokine production GO:0032642 31 0.011
nucleotide catabolic process GO:0009166 408 0.011
single organism nuclear import GO:1902593 104 0.011
Human
maintenance of location GO:0051235 112 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
rna interference GO:0016246 4 0.011
Human
actin filament based process GO:0030029 224 0.011
organophosphate catabolic process GO:0046434 430 0.011
ribonucleoprotein complex assembly GO:0022618 78 0.011
Human
regulation of gtpase activity GO:0043087 180 0.011
adult locomotory behavior GO:0008344 1 0.011
cellular response to molecule of bacterial origin GO:0071219 62 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
cell development GO:0048468 328 0.011
regulation of ion homeostasis GO:2000021 73 0.011
multi organism metabolic process GO:0044033 41 0.011
lipid biosynthetic process GO:0008610 177 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
embryonic hindlimb morphogenesis GO:0035116 2 0.011
regulation of glial cell proliferation GO:0060251 4 0.011
blood vessel morphogenesis GO:0048514 162 0.011
establishment of protein localization to membrane GO:0090150 121 0.010
ribonucleoprotein complex subunit organization GO:0071826 81 0.010
Human
response to abiotic stimulus GO:0009628 336 0.010
cellular chemical homeostasis GO:0055082 180 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
regulation of protein processing GO:0070613 150 0.010
cellular protein catabolic process GO:0044257 261 0.010
cell part morphogenesis GO:0032990 137 0.010
interferon beta production GO:0032608 23 0.010
Human
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010
positive regulation of synaptic transmission GO:0050806 4 0.010
cation transport GO:0006812 331 0.010

DHX58 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.028
cancer DOID:162 167 0.028
Human
disease of cellular proliferation DOID:14566 174 0.028
Human
organ system cancer DOID:0050686 164 0.025
Human
musculoskeletal system disease DOID:17 223 0.022
connective tissue disease DOID:65 109 0.022
central nervous system disease DOID:331 186 0.018
nervous system disease DOID:863 431 0.018
endocrine system disease DOID:28 26 0.015
Human
inherited metabolic disorder DOID:655 242 0.012
sensory system disease DOID:0050155 203 0.011