|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.915
|
Human Mouse Rat |
|
|
modified amino acid transport
|
GO:0072337 |
11 |
0.872
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.762
|
Human |
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
3 |
0.754
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.671
|
Human |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.664
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.594
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.590
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.586
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.575
|
Human Mouse Rat |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.556
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.542
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.528
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.515
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.481
|
Human |
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.475
|
|
|
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
2 |
0.421
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.415
|
Human Rat |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.411
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.389
|
Human |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.380
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.360
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.353
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.350
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.345
|
Human |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.337
|
Human Rat |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.321
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.310
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.309
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.296
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.293
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.291
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.279
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.276
|
Human Rat |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.248
|
Human Rat |
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.244
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.235
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.232
|
Rat |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.226
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.225
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.224
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.221
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.210
|
Human Rat |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.209
|
Human Rat |
|
|
startle response
|
GO:0001964 |
3 |
0.205
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.202
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.195
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.192
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.190
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.190
|
Human Rat |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.189
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.186
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.185
|
Human Rat |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.179
|
Human Rat |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.178
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.173
|
Rat |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.169
|
Human |
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.169
|
Human Mouse Rat |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.168
|
Human Rat |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.165
|
Human Rat |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.163
|
Human Rat |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.160
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.159
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.151
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.150
|
Human Rat |
|
|
cation transport
|
GO:0006812 |
331 |
0.149
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.147
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.146
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.145
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.144
|
Human |
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.143
|
Human |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.142
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.140
|
Human Rat |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.139
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.139
|
Human |
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.139
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.138
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.138
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.135
|
Human |
|
|
response to tumor cell
|
GO:0002347 |
10 |
0.135
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.132
|
Human |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.131
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.131
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.130
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.129
|
Human Rat |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.129
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.127
|
Human Rat |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.125
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.124
|
Human |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.123
|
Human Mouse Rat |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.121
|
Human Rat |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.116
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.115
|
Human |
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
17 |
0.115
|
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.115
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.114
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.114
|
Human Rat |
|
|
presynaptic membrane organization
|
GO:0097090 |
3 |
0.113
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.113
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.112
|
Human Rat |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.110
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.109
|
Human Rat |
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.108
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.107
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.107
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.106
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.104
|
Human Rat |
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.103
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.101
|
Human Rat |
|
|
immune effector process
|
GO:0002252 |
159 |
0.101
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.100
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.099
|
Mouse Rat |
|
|
epithelium development
|
GO:0060429 |
227 |
0.097
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.096
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.096
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.095
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.095
|
Human Rat |
|
|
memory
|
GO:0007613 |
3 |
0.094
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.093
|
|
|
|
negative regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010642 |
4 |
0.093
|
|
|
|
system process
|
GO:0003008 |
349 |
0.092
|
Human Mouse Rat |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.092
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.090
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.090
|
Human |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.090
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.089
|
Human |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.089
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.089
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.088
|
Human Rat |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.086
|
Human |
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.085
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.085
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.084
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.084
|
Human Rat |
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.083
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.082
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.082
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.082
|
Human |
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.081
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.080
|
|
|
|
amino acid betaine transport
|
GO:0015838 |
4 |
0.080
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.080
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.079
|
Human Rat |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.078
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.078
|
Human |
|
|
taxis
|
GO:0042330 |
157 |
0.078
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.077
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.077
|
Rat |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.076
|
Human Rat |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.076
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.075
|
Human Rat |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.074
|
Human |
|
|
negative regulation of neurological system process
|
GO:0031645 |
2 |
0.073
|
|
|
|
immunoglobulin biosynthetic process
|
GO:0002378 |
2 |
0.072
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.072
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.072
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.071
|
Human |
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.071
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.071
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.070
|
Human Mouse Rat |
|
|
immune system development
|
GO:0002520 |
195 |
0.070
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.070
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.069
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.069
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.068
|
Human |
|
|
limbic system development
|
GO:0021761 |
3 |
0.068
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.067
|
Human Rat |
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.066
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.066
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.065
|
Mouse Rat |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.065
|
Human Rat |
|
|
response to other organism
|
GO:0051707 |
261 |
0.065
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.064
|
Human Rat |
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.064
|
|
|
|
regulation of vasodilation
|
GO:0042312 |
4 |
0.064
|
Rat |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.064
|
|
|
|
regulation of excretion
|
GO:0044062 |
1 |
0.063
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.062
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.062
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.061
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.061
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.061
|
Rat |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.061
|
Human |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.061
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.059
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.059
|
Human Rat |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.058
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.058
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.057
|
Rat |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.057
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.057
|
Human |
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.057
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.057
|
Human Rat |
|
|
sodium ion homeostasis
|
GO:0055078 |
14 |
0.057
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.056
|
Human |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.056
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.055
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.055
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.055
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.055
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.055
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.055
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.055
|
Rat |
|
|
vasodilation
|
GO:0042311 |
4 |
0.055
|
Mouse Rat |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.054
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.054
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.054
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.054
|
Rat |
|
|
cytokine production
|
GO:0001816 |
247 |
0.054
|
Human |
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.053
|
Human Rat |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.053
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.053
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.053
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.053
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.053
|
Human |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.052
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.052
|
Human Rat |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.052
|
Rat |
|
|
negative regulation of nucleotide biosynthetic process
|
GO:0030809 |
11 |
0.052
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.051
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.051
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.051
|
Human |
|
|
negative regulation of cyclic nucleotide biosynthetic process
|
GO:0030803 |
10 |
0.051
|
Human |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.051
|
Human |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.050
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.050
|
Human |
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.050
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.050
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.050
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
3 |
0.050
|
|
|
|
cellular phosphate ion homeostasis
|
GO:0030643 |
4 |
0.050
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.050
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.049
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.049
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.049
|
Human |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.049
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.049
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.049
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.049
|
Human |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.048
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.048
|
|
|
|
positive regulation of phosphatidylinositol biosynthetic process
|
GO:0010513 |
3 |
0.048
|
Human |
|
|
inorganic anion transmembrane transport
|
GO:0098661 |
47 |
0.048
|
|
|
|
positive regulation of ligase activity
|
GO:0051351 |
19 |
0.048
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.047
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.047
|
Human Rat |
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.047
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.047
|
Human Rat |
|
|
renal absorption
|
GO:0070293 |
6 |
0.046
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.046
|
Human Rat |
|
|
innate immune response
|
GO:0045087 |
178 |
0.046
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.046
|
Human Rat |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.046
|
Human Rat |
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.045
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.045
|
Rat |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.045
|
Human |
|
|
adenylate cyclase inhibiting adrenergic receptor signaling pathway
|
GO:0071881 |
1 |
0.044
|
Human |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.044
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.044
|
Rat |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.044
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.044
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.043
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.043
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.043
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.043
|
Human |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.043
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.043
|
Human |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.043
|
Human |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.043
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.043
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.042
|
Rat |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.042
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.042
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.042
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.042
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.042
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.041
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.041
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.041
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.041
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.041
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.041
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.040
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.040
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.040
|
Human |
|
|
response to peptide
|
GO:1901652 |
65 |
0.040
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.040
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.040
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.039
|
Rat |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.039
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.039
|
Human |
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.039
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.038
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.038
|
Human |
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.038
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.038
|
|
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
29 |
0.038
|
Human |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.038
|
|
|
|
negative regulation of multicellular organismal metabolic process
|
GO:0044252 |
3 |
0.037
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.037
|
|
|
|
positive regulation of vasodilation
|
GO:0045909 |
4 |
0.037
|
Rat |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.037
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.037
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.037
|
Human |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.036
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.036
|
Rat |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.036
|
Human |
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
41 |
0.036
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.036
|
Rat |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.036
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.036
|
Rat |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.035
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.035
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.035
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.035
|
Human |
|
|
regulation of guanylate cyclase activity
|
GO:0031282 |
2 |
0.035
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.035
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.035
|
Human Mouse Rat |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.035
|
Human Rat |
|
|
blood circulation
|
GO:0008015 |
113 |
0.035
|
Human Mouse Rat |
|
|
tissue migration
|
GO:0090130 |
119 |
0.034
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.034
|
Human |
|
|
positive regulation of receptor internalization
|
GO:0002092 |
12 |
0.034
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.034
|
Human |
|
|
amino acid transport
|
GO:0006865 |
28 |
0.034
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.033
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.033
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.033
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.033
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.033
|
|
|
|
regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010640 |
6 |
0.033
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.033
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.033
|
|
|
|
regulation of cgmp biosynthetic process
|
GO:0030826 |
4 |
0.033
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.032
|
Human |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.032
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.032
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.032
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.032
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.032
|
Human Rat |
|
|
hydrogen transport
|
GO:0006818 |
23 |
0.031
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.031
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.031
|
Human Rat |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.031
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.031
|
Human |
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.031
|
|
|
|
positive regulation of ubiquitin protein transferase activity
|
GO:0051443 |
18 |
0.031
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.031
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.031
|
Human |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.031
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.031
|
Human |
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.030
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.030
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.030
|
Human Mouse Rat |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.030
|
|
|
|
growth
|
GO:0040007 |
202 |
0.030
|
Mouse Rat |
|
|
regulation of receptor internalization
|
GO:0002090 |
15 |
0.030
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.029
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.029
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.029
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.029
|
Human |
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.029
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.029
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.029
|
|
|
|
cellular trivalent inorganic anion homeostasis
|
GO:0072502 |
4 |
0.029
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.029
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.029
|
|
|
|
oligodendrocyte development
|
GO:0014003 |
6 |
0.029
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.028
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.028
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.028
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.028
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.028
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.028
|
Human |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.028
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.028
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.028
|
|
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
2 |
0.028
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.027
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.027
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.027
|
Human |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.027
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.027
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.027
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.027
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.027
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.027
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.027
|
|
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.027
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.027
|
|
|
|
negative regulation of collagen metabolic process
|
GO:0010713 |
3 |
0.027
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.026
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.026
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.026
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.026
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.026
|
Human |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.026
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.026
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.026
|
Human |
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.026
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.026
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.026
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.026
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.025
|
Rat |
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.025
|
Human |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.025
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.025
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.025
|
Human |
|
|
cgmp metabolic process
|
GO:0046068 |
19 |
0.025
|
Human |
|
|
oocyte development
|
GO:0048599 |
1 |
0.025
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.025
|
Rat |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.024
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.024
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.024
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.024
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.024
|
Human |
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.024
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.024
|
Human |
|
|
response to wounding
|
GO:0009611 |
168 |
0.024
|
Human Rat |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.024
|
Human |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.024
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.024
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.024
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.024
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.024
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.024
|
Human |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.023
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.023
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.023
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.023
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.023
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.023
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.023
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.023
|
Human |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.023
|
Mouse |
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.023
|
|
|
|
copulation
|
GO:0007620 |
1 |
0.023
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.023
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.023
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.023
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.023
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.023
|
Human |
|
|
spermatid development
|
GO:0007286 |
4 |
0.023
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.023
|
|
|
|
axon ensheathment in central nervous system
|
GO:0032291 |
1 |
0.023
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.023
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.023
|
Human |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.023
|
Human |
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
26 |
0.023
|
Human |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.022
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.022
|
|
|
|
trivalent inorganic anion homeostasis
|
GO:0072506 |
7 |
0.022
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.022
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.022
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.022
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.022
|
Rat |
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.022
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.022
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.022
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.022
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.022
|
|
|
|
endothelial cell development
|
GO:0001885 |
18 |
0.022
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.022
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.022
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.021
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.021
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.021
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.021
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.021
|
Human |
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.021
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.021
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.021
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.021
|
Human |
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
2 |
0.021
|
Human |
|
|
peptide transport
|
GO:0015833 |
74 |
0.021
|
Human |
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.021
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.021
|
Human |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.021
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.021
|
Human Rat |
|
|
phospholipase c activating adrenergic receptor signaling pathway
|
GO:0071882 |
1 |
0.021
|
Human |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.020
|
Human |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.020
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.020
|
Human |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.020
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.020
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.020
|
|
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.020
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.020
|
Human |
