Homo sapiens

62 known processes

BLOC1S3

biogenesis of lysosomal organelles complex-1, subunit 3

(Aliases: FLJ26676,FLJ26641,RP,HPS8,BLOS3)

BLOC1S3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anterograde axon cargo transport GO:0008089 1 0.964
endosome to pigment granule transport GO:0043485 9 0.820
cellular pigment accumulation GO:0043482 9 0.806
melanosome localization GO:0032400 7 0.693
pigment granule maturation GO:0048757 9 0.600
oxidation reduction process GO:0055114 396 0.493
positive regulation of natural killer cell activation GO:0032816 8 0.368
mitochondrial membrane organization GO:0007006 40 0.338
regulation of natural killer cell activation GO:0032814 9 0.229
pigment granule transport GO:0051904 5 0.197
melanosome transport GO:0032402 5 0.185
endosomal transport GO:0016197 129 0.168
protein acetylation GO:0006473 116 0.167
natural killer cell activation GO:0030101 12 0.142
membrane organization GO:0061024 292 0.132
positive regulation of pigment cell differentiation GO:0050942 2 0.115
coagulation GO:0050817 78 0.112
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.101
positive regulation of developmental process GO:0051094 314 0.098
positive regulation of cell proliferation GO:0008284 301 0.095
pigment granule localization GO:0051875 7 0.089
regulation of body fluid levels GO:0050878 99 0.086
secretion by cell GO:0032940 226 0.085
peptidyl lysine modification GO:0018205 144 0.084
mitochondrion organization GO:0007005 156 0.074
regulation of developmental pigmentation GO:0048070 2 0.062
positive regulation of developmental pigmentation GO:0048087 2 0.052
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.052
developmental pigmentation GO:0048066 12 0.052
axon cargo transport GO:0008088 2 0.047
regulation of cell differentiation GO:0045595 393 0.047
protein acylation GO:0043543 138 0.047
regulation of membrane permeability GO:0090559 25 0.046
apoptotic signaling pathway GO:0097190 268 0.044
cell cell signaling GO:0007267 155 0.044
positive regulation of immune system process GO:0002684 283 0.044
regulation of pigment cell differentiation GO:0050932 2 0.044
vesicle mediated transport GO:0016192 371 0.044
positive regulation of cell differentiation GO:0045597 211 0.044
regulation of intracellular transport GO:0032386 195 0.043
single organism cellular localization GO:1902580 332 0.042
leukocyte activation GO:0045321 164 0.042
purine ribonucleoside catabolic process GO:0046130 398 0.041
cytoplasmic transport GO:0016482 379 0.040
hemostasis GO:0007599 76 0.040
regulation of cellular amino acid metabolic process GO:0006521 6 0.039
neuron projection development GO:0031175 106 0.038
peptidyl lysine acetylation GO:0018394 101 0.038
single organism membrane organization GO:0044802 268 0.037
generation of precursor metabolites and energy GO:0006091 68 0.036
cellular amine metabolic process GO:0044106 41 0.035
mitochondrial outer membrane permeabilization GO:0097345 15 0.035
establishment of vesicle localization GO:0051650 23 0.035
nervous system development GO:0007399 293 0.035
locomotory behavior GO:0007626 1 0.034
regulation of cell activation GO:0050865 125 0.034
cellular respiration GO:0045333 21 0.033
pigmentation GO:0043473 22 0.033
neurogenesis GO:0022008 169 0.033
amine metabolic process GO:0009308 44 0.033
cell projection organization GO:0030030 252 0.033
positive regulation of leukocyte activation GO:0002696 80 0.033
multicellular organismal aging GO:0010259 3 0.033
extrinsic apoptotic signaling pathway GO:0097191 119 0.031
melanocyte differentiation GO:0030318 2 0.031
cellular ketone metabolic process GO:0042180 80 0.030
intracellular protein transport GO:0006886 270 0.030
regulation of locomotion GO:0040012 329 0.030
positive regulation of lymphocyte activation GO:0051251 73 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
microtubule based process GO:0007017 210 0.029
epithelial cell differentiation GO:0030855 141 0.029
synaptic vesicle transport GO:0048489 5 0.029
organophosphate catabolic process GO:0046434 430 0.028
cellular amino acid metabolic process GO:0006520 116 0.028
epithelium development GO:0060429 227 0.027
apoptotic mitochondrial changes GO:0008637 57 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
neuron differentiation GO:0030182 138 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.026
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 16 0.025
regulation of cellular amine metabolic process GO:0033238 11 0.025
post embryonic development GO:0009791 2 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
secretion GO:0046903 254 0.025
regulation of lymphocyte activation GO:0051249 103 0.025
regulation of protein transport GO:0051223 213 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
mitotic cell cycle GO:0000278 326 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
response to abiotic stimulus GO:0009628 336 0.023
generation of neurons GO:0048699 152 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
regulation of leukocyte activation GO:0002694 115 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
cardiovascular system development GO:0072358 262 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
establishment of melanosome localization GO:0032401 5 0.022
segmentation GO:0035282 4 0.022
protein secretion GO:0009306 98 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
response to wounding GO:0009611 168 0.022
positive regulation of transport GO:0051050 336 0.022
regulation of cell cycle GO:0051726 393 0.022
transmembrane transport GO:0055085 399 0.021
mitotic cell cycle process GO:1903047 286 0.021
positive regulation of cell activation GO:0050867 81 0.021
nucleotide catabolic process GO:0009166 408 0.021
purine nucleotide catabolic process GO:0006195 405 0.021
lymphocyte activation GO:0046649 133 0.021
regulation of protein localization GO:0032880 296 0.020
ribonucleotide catabolic process GO:0009261 405 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
lipid metabolic process GO:0006629 381 0.020
signal release GO:0023061 70 0.020
positive regulation of catabolic process GO:0009896 310 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
positive regulation of phosphorylation GO:0042327 394 0.019
cell development GO:0048468 328 0.019
female gamete generation GO:0007292 2 0.019
endothelial cell proliferation GO:0001935 65 0.019
protein catabolic process GO:0030163 325 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
neurotransmitter secretion GO:0007269 4 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
cell morphogenesis GO:0000902 296 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
ribonucleoprotein complex assembly GO:0022618 78 0.018
response to oxygen containing compound GO:1901700 369 0.018
cellular component morphogenesis GO:0032989 314 0.018
cellular protein catabolic process GO:0044257 261 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
positive regulation of cell death GO:0010942 263 0.018
cell adhesion GO:0007155 325 0.018
rho protein signal transduction GO:0007266 26 0.018
positive regulation of hydrolase activity GO:0051345 331 0.017
regulation of cell cycle process GO:0010564 266 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
ras protein signal transduction GO:0007265 73 0.017
determination of adult lifespan GO:0008340 2 0.017
response to other organism GO:0051707 261 0.017
establishment of organelle localization GO:0051656 59 0.017
oogenesis GO:0048477 2 0.017
regeneration GO:0031099 4 0.017
immune response GO:0006955 307 0.017
memory GO:0007613 3 0.017
cellular response to endogenous stimulus GO:0071495 336 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
regulation of proteolysis GO:0030162 293 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
vasculature development GO:0001944 181 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
regulation of transferase activity GO:0051338 355 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
peripheral nervous system development GO:0007422 2 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
biological adhesion GO:0022610 331 0.016
regulation of cellular response to stress GO:0080135 244 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
aerobic respiration GO:0009060 7 0.016
mitochondrial transport GO:0006839 60 0.016
neuron development GO:0048666 113 0.016
adult locomotory behavior GO:0008344 1 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
maintenance of location GO:0051235 112 0.015
organ morphogenesis GO:0009887 147 0.015
carbohydrate metabolic process GO:0005975 207 0.015
purine containing compound catabolic process GO:0072523 411 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
protein processing GO:0016485 226 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
defense response GO:0006952 315 0.015
blood vessel morphogenesis GO:0048514 162 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
regulation of kinase activity GO:0043549 314 0.015
chemical homeostasis GO:0048878 306 0.015
blastoderm segmentation GO:0007350 2 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
protein localization to organelle GO:0033365 280 0.014
regulation of cell migration GO:0030334 289 0.014
energy derivation by oxidation of organic compounds GO:0015980 43 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
hindbrain development GO:0030902 3 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
small molecule biosynthetic process GO:0044283 157 0.014
response to external biotic stimulus GO:0043207 261 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
response to biotic stimulus GO:0009607 276 0.014
cytokine production GO:0001816 247 0.014
response to cytokine GO:0034097 232 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
rna splicing GO:0008380 131 0.014
regulation of rna splicing GO:0043484 62 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
positive regulation of transferase activity GO:0051347 227 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
protein ubiquitination GO:0016567 314 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
organelle assembly GO:0070925 176 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
nucleoside catabolic process GO:0009164 408 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
anterior posterior axis specification GO:0009948 2 0.014
negative regulation of cell death GO:0060548 345 0.014
cellular response to oxygen containing compound GO:1901701 276 0.013
cellular protein complex assembly GO:0043623 188 0.013
innate immune response GO:0045087 178 0.013
wound healing GO:0042060 115 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
microtubule based movement GO:0007018 32 0.013
system process GO:0003008 349 0.013
cellular chemical homeostasis GO:0055082 180 0.013
actin filament based process GO:0030029 224 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
cell cycle phase transition GO:0044770 173 0.013
regulation of immune response GO:0050776 201 0.013
mapk cascade GO:0000165 288 0.013
cellular response to abiotic stimulus GO:0071214 117 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
cellular homeostasis GO:0019725 196 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
regulation of cellular component movement GO:0051270 334 0.013
neuromuscular junction development GO:0007528 3 0.013
oocyte development GO:0048599 1 0.013
positive regulation of epithelial cell proliferation GO:0050679 65 0.013
regulation of protein binding GO:0043393 66 0.013
cation transport GO:0006812 331 0.013
protein oligomerization GO:0051259 173 0.013
oocyte differentiation GO:0009994 2 0.013
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 16 0.013
mitotic cell cycle phase transition GO:0044772 162 0.012
phototransduction GO:0007602 3 0.012
protein maturation GO:0051604 233 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
synaptic transmission GO:0007268 61 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
regulation of gtpase activity GO:0043087 180 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
rna splicing via transesterification reactions GO:0000375 90 0.012
spermatid differentiation GO:0048515 4 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
organelle localization GO:0051640 84 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
regulation of mapk cascade GO:0043408 262 0.012
regulation of angiogenesis GO:0045765 92 0.012
regulation of response to external stimulus GO:0032101 222 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
actin cytoskeleton organization GO:0030036 207 0.012
cell fate determination GO:0001709 3 0.012
gtp metabolic process GO:0046039 239 0.012
endosome to melanosome transport GO:0035646 9 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
nerve development GO:0021675 4 0.012
organ formation GO:0048645 3 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
protein polymerization GO:0051258 71 0.011
negative regulation of protein modification process GO:0031400 200 0.011
compound eye development GO:0048749 1 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
regulation of secretion GO:0051046 194 0.011
viral process GO:0016032 146 0.011
regulation of cell motility GO:2000145 299 0.011
circulatory system development GO:0072359 262 0.011
cellular response to external stimulus GO:0071496 111 0.011
striated muscle cell apoptotic process GO:0010658 3 0.011
response to lipid GO:0033993 206 0.011
rhythmic behavior GO:0007622 2 0.011
organelle fission GO:0048285 149 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
atp metabolic process GO:0046034 176 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
ion transmembrane transport GO:0034220 338 0.011
negative regulation of cell cycle GO:0045786 193 0.011
angiogenesis GO:0001525 147 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
regulation of protein maturation GO:1903317 150 0.011
regulation of growth GO:0040008 165 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
metal ion homeostasis GO:0055065 169 0.011
dephosphorylation GO:0016311 209 0.011
protein targeting GO:0006605 187 0.011
cell activation GO:0001775 213 0.011
cellular cation homeostasis GO:0030003 163 0.011
immune system development GO:0002520 195 0.011
chromatin modification GO:0016568 298 0.011
epithelial cell proliferation GO:0050673 128 0.011
positive regulation of locomotion GO:0040017 186 0.011
positive regulation of angiogenesis GO:0045766 51 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
response to fungus GO:0009620 4 0.010
multi organism cellular process GO:0044764 156 0.010
regulation of peptidase activity GO:0052547 180 0.010
regulation of protein kinase activity GO:0045859 289 0.010
sulfur compound metabolic process GO:0006790 101 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
endocytosis GO:0006897 159 0.010
tripartite regional subdivision GO:0007351 2 0.010
cell type specific apoptotic process GO:0097285 125 0.010
negative regulation of protein maturation GO:1903318 142 0.010
morphogenesis of embryonic epithelium GO:0016331 4 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
positive regulation of cell migration GO:0030335 172 0.010
negative regulation of cell differentiation GO:0045596 171 0.010
positive regulation of kinase activity GO:0033674 204 0.010
positive regulation of protein transport GO:0051222 135 0.010
peptidyl tyrosine phosphorylation GO:0018108 170 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
metencephalon development GO:0022037 2 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
inner ear morphogenesis GO:0042472 4 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
regulation of multi organism process GO:0043900 157 0.010
actin mediated cell contraction GO:0070252 12 0.010
regulation of cytokine production GO:0001817 232 0.010
cell growth GO:0016049 160 0.010

BLOC1S3 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.020
nervous system disease DOID:863 431 0.020
disease of metabolism DOID:0014667 295 0.018
musculoskeletal system disease DOID:17 223 0.017
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
central nervous system disease DOID:331 186 0.014
inherited metabolic disorder DOID:655 242 0.013
retinal disease DOID:5679 118 0.013
connective tissue disease DOID:65 109 0.012
disease of cellular proliferation DOID:14566 174 0.011
cancer DOID:162 167 0.011
organ system cancer DOID:0050686 164 0.011
immune system disease DOID:2914 155 0.011