Homo sapiens

104 known processes

ATG7

ATG7 autophagy related 7 homolog (S. cerevisiae)

(Aliases: GSA7,DKFZp434N0735,APG7L,APG7-LIKE)

ATG7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
autophagic vacuole assembly GO:0000045 19 0.923
vacuole organization GO:0007033 44 0.897
lipoprotein metabolic process GO:0042157 42 0.716
vacuolar transport GO:0007034 34 0.454
Yeast
c terminal protein amino acid modification GO:0018410 1 0.449
Yeast
macroautophagy GO:0016236 39 0.435
protein modification by small protein conjugation GO:0032446 342 0.390
Yeast Fly
protein targeting to vacuole GO:0006623 8 0.347
Yeast
cytoplasmic transport GO:0016482 379 0.302
Yeast
intracellular protein transport GO:0006886 270 0.282
Yeast
determination of adult lifespan GO:0008340 2 0.267
Worm Fly
cellular amine metabolic process GO:0044106 41 0.260
protein localization to vacuole GO:0072665 11 0.259
Yeast
lipoprotein biosynthetic process GO:0042158 33 0.251
protein localization to organelle GO:0033365 280 0.246
Yeast
autophagic cell death GO:0048102 3 0.233
protein lipidation GO:0006497 33 0.219
establishment of protein localization to organelle GO:0072594 172 0.217
Yeast
multicellular organismal aging GO:0010259 3 0.198
Worm Fly
cellular ion homeostasis GO:0006873 168 0.177
amine metabolic process GO:0009308 44 0.176
regulation of cytokine production GO:0001817 232 0.161
membrane organization GO:0061024 292 0.159
Yeast
response to external biotic stimulus GO:0043207 261 0.148
Fly
cellular response to external stimulus GO:0071496 111 0.143
protein targeting GO:0006605 187 0.143
Yeast
chromatin organization GO:0006325 351 0.131
protein ubiquitination GO:0016567 314 0.130
defense response GO:0006952 315 0.125
Fly
growth GO:0040007 202 0.121
Worm
vasodilation GO:0042311 4 0.113
regulation of cellular amino acid metabolic process GO:0006521 6 0.107
response to biotic stimulus GO:0009607 276 0.098
Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.097
actin filament based process GO:0030029 224 0.096
single organism membrane organization GO:0044802 268 0.095
Yeast
post translational protein modification GO:0043687 7 0.092
Yeast
organelle assembly GO:0070925 176 0.088
regulation of cellular amine metabolic process GO:0033238 11 0.084
defense response to bacterium GO:0042742 63 0.082
metal ion transport GO:0030001 272 0.082
cellular ketone metabolic process GO:0042180 80 0.080
myosin filament assembly GO:0031034 2 0.080
autophagy GO:0006914 88 0.079
ion homeostasis GO:0050801 230 0.079
cilium assembly GO:0042384 63 0.078
cellular component assembly involved in morphogenesis GO:0010927 73 0.077
cellular response to nutrient levels GO:0031669 69 0.076
positive regulation of catabolic process GO:0009896 310 0.076
negative regulation of cellular amine metabolic process GO:0033239 3 0.076
immune response GO:0006955 307 0.075
single organism cellular localization GO:1902580 332 0.073
Yeast
purine ribonucleoside metabolic process GO:0046128 437 0.072
response to other organism GO:0051707 261 0.069
Fly
post embryonic development GO:0009791 2 0.069
Worm Fly
negative regulation of protein metabolic process GO:0051248 391 0.068
regulation of cellular ketone metabolic process GO:0010565 50 0.068
histone modification GO:0016570 251 0.067
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.067
positive regulation of autophagy GO:0010508 24 0.060
cellular amino acid metabolic process GO:0006520 116 0.060
protein acetylation GO:0006473 116 0.059
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.058
cytokine production GO:0001816 247 0.057
regulation of cellular response to stress GO:0080135 244 0.056
response to starvation GO:0042594 59 0.055
protein acylation GO:0043543 138 0.054
negative regulation of protein modification process GO:0031400 200 0.054
regulation of autophagy GO:0010506 52 0.053
immune effector process GO:0002252 159 0.052
Fly
positive regulation of transport GO:0051050 336 0.050
response to fungus GO:0009620 4 0.050
negative regulation of axonogenesis GO:0050771 4 0.049
internal protein amino acid acetylation GO:0006475 101 0.049
striated muscle myosin thick filament assembly GO:0071688 2 0.048
histone acetylation GO:0016573 93 0.047
regulation of cell morphogenesis GO:0022604 153 0.047
cation transport GO:0006812 331 0.047
purine nucleoside triphosphate metabolic process GO:0009144 412 0.046
cell morphogenesis GO:0000902 296 0.046
cellular response to extracellular stimulus GO:0031668 72 0.046
internal peptidyl lysine acetylation GO:0018393 97 0.045
calcium ion homeostasis GO:0055074 122 0.043
cellular response to starvation GO:0009267 58 0.043
regulation of protein localization GO:0032880 296 0.043
protein processing GO:0016485 226 0.043
regulation of cilium assembly GO:1902017 6 0.041
negative regulation of cell cycle GO:0045786 193 0.040
interspecies interaction between organisms GO:0044419 156 0.040
cellular calcium ion homeostasis GO:0006874 117 0.039
cellular chemical homeostasis GO:0055082 180 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.038
cellular component morphogenesis GO:0032989 314 0.038
establishment of protein localization to vacuole GO:0072666 8 0.038
Yeast
nucleoside catabolic process GO:0009164 408 0.038
regulation of establishment of protein localization GO:0070201 242 0.037
cellular macromolecular complex assembly GO:0034622 324 0.037
regulation of proteolysis GO:0030162 293 0.037
ras protein signal transduction GO:0007265 73 0.037
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
cellular lipid metabolic process GO:0044255 303 0.036
purine nucleoside catabolic process GO:0006152 398 0.036
cytosolic calcium ion homeostasis GO:0051480 89 0.036
positive regulation of cellular amine metabolic process GO:0033240 7 0.035
mitochondrion degradation GO:0000422 8 0.035
Yeast
response to virus GO:0009615 126 0.035
Fly
multi organism cellular process GO:0044764 156 0.035
regulation of anatomical structure size GO:0090066 101 0.034
chemical homeostasis GO:0048878 306 0.034
maintenance of location GO:0051235 112 0.033
peptidyl lysine modification GO:0018205 144 0.033
cation homeostasis GO:0055080 189 0.033
negative regulation of programmed cell death GO:0043069 321 0.033
purine ribonucleoside catabolic process GO:0046130 398 0.033
nucleoside triphosphate metabolic process GO:0009141 422 0.032
striated muscle cell differentiation GO:0051146 43 0.032
cellular divalent inorganic cation homeostasis GO:0072503 128 0.032
protein catabolic process GO:0030163 325 0.031
blood vessel remodeling GO:0001974 2 0.031
muscle structure development GO:0061061 98 0.031
positive regulation of interferon beta production GO:0032728 17 0.031
extrinsic apoptotic signaling pathway GO:0097191 119 0.031
actin cytoskeleton organization GO:0030036 207 0.031
defense response to other organism GO:0098542 129 0.030
Fly
positive regulation of interleukin 13 production GO:0032736 4 0.030
female gamete generation GO:0007292 2 0.030
Fly
defense response to gram positive bacterium GO:0050830 29 0.029
glycosyl compound catabolic process GO:1901658 413 0.029
regulation of protein transport GO:0051223 213 0.029
cellular protein complex assembly GO:0043623 188 0.029
regeneration GO:0031099 4 0.029
system process GO:0003008 349 0.028
regulation of homeostatic process GO:0032844 121 0.028
positive regulation of cytokine production GO:0001819 167 0.028
negative regulation of organelle organization GO:0010639 126 0.028
regulation of calcium ion transport into cytosol GO:0010522 33 0.028
peptidyl lysine acetylation GO:0018394 101 0.028
nitrogen compound transport GO:0071705 191 0.028
covalent chromatin modification GO:0016569 254 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
cell projection assembly GO:0030031 126 0.027
ribonucleoside monophosphate metabolic process GO:0009161 187 0.027
regulation of cellular component biogenesis GO:0044087 281 0.027
regulation of metal ion transport GO:0010959 120 0.027
defense response to virus GO:0051607 71 0.027
Fly
purine containing compound catabolic process GO:0072523 411 0.027
positive regulation of developmental process GO:0051094 314 0.026
secretion GO:0046903 254 0.026
response to cytokine GO:0034097 232 0.026
purine ribonucleotide catabolic process GO:0009154 404 0.026
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
regulation of reactive oxygen species metabolic process GO:2000377 41 0.026
cellular homeostasis GO:0019725 196 0.026
ribonucleoside triphosphate metabolic process GO:0009199 412 0.026
regulation of cell projection organization GO:0031344 107 0.026
regulation of nucleoside metabolic process GO:0009118 209 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.025
regulation of protein catabolic process GO:0042176 155 0.025
inorganic ion transmembrane transport GO:0098660 231 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
regulation of chromosome organization GO:0033044 103 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
lipid metabolic process GO:0006629 381 0.024
negative regulation of histone acetylation GO:0035067 6 0.024
cell projection organization GO:0030030 252 0.024
cellular macromolecule catabolic process GO:0044265 380 0.024
regulation of body fluid levels GO:0050878 99 0.024
lytic vacuole organization GO:0080171 24 0.024
purine nucleoside monophosphate metabolic process GO:0009126 186 0.024
cation transmembrane transport GO:0098655 238 0.024
sequestering of calcium ion GO:0051208 17 0.024
regulation of histone acetylation GO:0035065 19 0.024
transmembrane transport GO:0055085 399 0.024
cellular response to cytokine stimulus GO:0071345 181 0.024
heart contraction GO:0060047 62 0.024
microtubule based process GO:0007017 210 0.024
cilium organization GO:0044782 68 0.023
dephosphorylation GO:0016311 209 0.023
muscle cell differentiation GO:0042692 63 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
circulatory system process GO:0003013 113 0.023
regulation of protein maturation GO:1903317 150 0.023
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
central nervous system development GO:0007417 123 0.022
response to inorganic substance GO:0010035 127 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
calcium ion transport GO:0006816 147 0.022
memory GO:0007613 3 0.022
negative regulation of chromosome organization GO:2001251 48 0.022
ribonucleoside catabolic process GO:0042454 406 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.021
atp metabolic process GO:0046034 176 0.021
negative regulation of proteolysis GO:0045861 132 0.021
response to endoplasmic reticulum stress GO:0034976 49 0.021
endocytosis GO:0006897 159 0.021
striated muscle cell development GO:0055002 27 0.020
regulation of protein secretion GO:0050708 86 0.020
organophosphate catabolic process GO:0046434 430 0.020
nucleotide catabolic process GO:0009166 408 0.020
regulation of secretion by cell GO:1903530 177 0.020
single organism membrane fusion GO:0044801 37 0.020
positive regulation of cell proliferation GO:0008284 301 0.020
ribonucleotide biosynthetic process GO:0009260 81 0.020
protein maturation GO:0051604 233 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
cytokine secretion GO:0050663 64 0.019
positive regulation of interleukin 4 production GO:0032753 3 0.019
protein oligomerization GO:0051259 173 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
positive regulation of necrotic cell death GO:0010940 4 0.019
apoptotic signaling pathway GO:0097190 268 0.019
histone h4 acetylation GO:0043967 47 0.019
small gtpase mediated signal transduction GO:0007264 78 0.019
cardiac muscle cell contraction GO:0086003 4 0.019
negative regulation of cell death GO:0060548 345 0.019
cellular cation homeostasis GO:0030003 163 0.019
regulation of cellular protein catabolic process GO:1903362 96 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
regulation of immune effector process GO:0002697 91 0.019
Fly
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
cellular metal ion homeostasis GO:0006875 146 0.019
glycoprotein metabolic process GO:0009100 110 0.018
negative regulation of sequestering of calcium ion GO:0051283 41 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.018
oogenesis GO:0048477 2 0.018
Fly
associative learning GO:0008306 1 0.018
negative regulation of peptidyl lysine acetylation GO:2000757 8 0.018
divalent metal ion transport GO:0070838 152 0.018
calcium ion transport into cytosol GO:0060402 48 0.018
rna interference GO:0016246 4 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
negative regulation of catalytic activity GO:0043086 335 0.018
regulation of sequestering of calcium ion GO:0051282 41 0.018
positive regulation of apoptotic process GO:0043065 246 0.017
taxis GO:0042330 157 0.017
negative regulation of transferase activity GO:0051348 124 0.017
lysosome organization GO:0007040 24 0.017
adult locomotory behavior GO:0008344 1 0.017
histone h4 k16 acetylation GO:0043984 14 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
chromatin modification GO:0016568 298 0.017
immune system development GO:0002520 195 0.017
endosomal transport GO:0016197 129 0.017
regulation of protein ubiquitination GO:0031396 95 0.017
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
negative regulation of homeostatic process GO:0032845 59 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
actomyosin structure organization GO:0031032 59 0.016
regulation of protein kinase activity GO:0045859 289 0.016
cell cycle arrest GO:0007050 71 0.016
positive regulation of interleukin 13 biosynthetic process GO:0045368 1 0.016
motor neuron axon guidance GO:0008045 2 0.016
positive regulation of synaptic transmission GO:0050806 4 0.016
cell growth GO:0016049 160 0.016
positive regulation of kinase activity GO:0033674 204 0.016
cellular protein catabolic process GO:0044257 261 0.016
sleep GO:0030431 2 0.016
regulation of protein binding GO:0043393 66 0.016
neuromuscular junction development GO:0007528 3 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
negative regulation of cell growth GO:0030308 83 0.015
phospholipid metabolic process GO:0006644 99 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
response to abiotic stimulus GO:0009628 336 0.015
compound eye development GO:0048749 1 0.015
cellular response to abiotic stimulus GO:0071214 117 0.015
gtp metabolic process GO:0046039 239 0.015
cytoskeleton dependent intracellular transport GO:0030705 21 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
establishment of organelle localization GO:0051656 59 0.015
catecholamine secretion GO:0050432 1 0.015
sphingolipid metabolic process GO:0006665 38 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
regulation of interferon beta production GO:0032648 22 0.015
peripheral nervous system development GO:0007422 2 0.015
regulation of kinase activity GO:0043549 314 0.015
nerve development GO:0021675 4 0.015
aging GO:0007568 66 0.015
Worm Fly
positive regulation of protein phosphorylation GO:0001934 313 0.015
segmentation GO:0035282 4 0.015
nuclear transport GO:0051169 179 0.015
regulation of binding GO:0051098 111 0.014
positive regulation of secretion GO:0051047 116 0.014
innate immune response GO:0045087 178 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
rab protein signal transduction GO:0032482 4 0.014
positive regulation of cell death GO:0010942 263 0.014
positive regulation of ras gtpase activity GO:0032320 117 0.014
actin mediated cell contraction GO:0070252 12 0.014
cell development GO:0048468 328 0.014
Fly
basic amino acid transport GO:0015802 3 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
membrane lipid metabolic process GO:0006643 53 0.014
protein localization to membrane GO:0072657 160 0.014
response to bacterium GO:0009617 144 0.014
regulation of dephosphorylation GO:0035303 96 0.014
nervous system development GO:0007399 293 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
alcohol metabolic process GO:0006066 114 0.013
ribose phosphate biosynthetic process GO:0046390 82 0.013
muscle cell development GO:0055001 29 0.013
negative regulation of protein ubiquitination GO:0031397 35 0.013
locomotory behavior GO:0007626 1 0.013
regulation of cytokine secretion GO:0050707 57 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
regulation of glial cell differentiation GO:0045685 3 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
cellular biogenic amine metabolic process GO:0006576 34 0.013
long term memory GO:0007616 2 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
cell projection morphogenesis GO:0048858 129 0.013
actin filament based movement GO:0030048 17 0.013
regulation of histone modification GO:0031056 47 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
regulation of protein complex assembly GO:0043254 147 0.013
negative regulation of protein maturation GO:1903318 142 0.013
negative regulation of protein acetylation GO:1901984 11 0.013
purine containing compound biosynthetic process GO:0072522 88 0.013
neurological system process GO:0050877 163 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
somatic muscle development GO:0007525 1 0.012
positive regulation of cytokine biosynthetic process GO:0042108 25 0.012
response to hormone GO:0009725 175 0.012
cellular response to biotic stimulus GO:0071216 71 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
regulation of growth GO:0040008 165 0.012
monovalent inorganic cation transport GO:0015672 128 0.012
organic anion transport GO:0015711 103 0.012
early endosome to golgi transport GO:0034498 3 0.012
head development GO:0060322 108 0.012
negative regulation of protein catabolic process GO:0042177 59 0.012
atp catabolic process GO:0006200 157 0.012
regulation of cell cycle GO:0051726 393 0.012
vascular process in circulatory system GO:0003018 29 0.012
regulation of interleukin 4 biosynthetic process GO:0045402 2 0.012
oxidation reduction process GO:0055114 396 0.012
positive regulation of interleukin 4 biosynthetic process GO:0045404 1 0.012
rho protein signal transduction GO:0007266 26 0.012
gtp catabolic process GO:0006184 237 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
cell division GO:0051301 168 0.012
monovalent inorganic cation homeostasis GO:0055067 37 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
ethanolamine containing compound metabolic process GO:0042439 26 0.012
vesicle transport along microtubule GO:0047496 4 0.012
regulation of cell differentiation GO:0045595 393 0.012
carboxylic acid transport GO:0046942 63 0.012
interferon alpha production GO:0032607 11 0.011
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.011
positive regulation of immune system process GO:0002684 283 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
regulation of intracellular transport GO:0032386 195 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
regulation of secretion GO:0051046 194 0.011
regulation of protein acetylation GO:1901983 25 0.011
carbohydrate metabolic process GO:0005975 207 0.011
regulation of cytokine biosynthetic process GO:0042035 35 0.011
multicellular organismal response to stress GO:0033555 1 0.011
translation GO:0006412 132 0.011
regulation of cellular response to growth factor stimulus GO:0090287 76 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
biological adhesion GO:0022610 331 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
organelle localization GO:0051640 84 0.011
regulation of protein processing GO:0070613 150 0.011
positive regulation of mucus secretion GO:0070257 1 0.011
tube morphogenesis GO:0035239 95 0.011
regulation of blood vessel size GO:0050880 18 0.011
regulation of cell division GO:0051302 116 0.011
regulation of interleukin 10 biosynthetic process GO:0045074 2 0.011
response to axon injury GO:0048678 1 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
tissue regeneration GO:0042246 3 0.011
hyperosmotic response GO:0006972 4 0.010
macromolecule glycosylation GO:0043413 63 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
positive regulation of gtp catabolic process GO:0033126 166 0.010
regulation of actin filament polymerization GO:0030833 50 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
chemotaxis GO:0006935 157 0.010
developmental programmed cell death GO:0010623 3 0.010
Fly
regulation of synaptic plasticity GO:0048167 3 0.010
cytokine metabolic process GO:0042107 38 0.010
negative regulation of cellular catabolic process GO:0031330 83 0.010
regulation of nervous system development GO:0051960 88 0.010
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
meiosis i GO:0007127 4 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
regulation of cell cycle process GO:0010564 266 0.010
cell part morphogenesis GO:0032990 137 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
actin filament polymerization GO:0030041 45 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010
regulation of tube size GO:0035150 18 0.010
response to oxygen containing compound GO:1901700 369 0.010

ATG7 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.056
musculoskeletal system disease DOID:17 223 0.039
connective tissue disease DOID:65 109 0.039
lysosomal storage disease DOID:3211 47 0.036
inherited metabolic disorder DOID:655 242 0.036
disease of cellular proliferation DOID:14566 174 0.022
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
bone disease DOID:0080001 88 0.021
sensory system disease DOID:0050155 203 0.018
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.018
neurodegenerative disease DOID:1289 102 0.016
immune system disease DOID:2914 155 0.015
cancer DOID:162 167 0.015
organ system cancer DOID:0050686 164 0.015
retinal disease DOID:5679 118 0.014
cardiovascular system disease DOID:1287 106 0.013
brain disease DOID:936 73 0.010