|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.945
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.938
|
|
|
|
nucleosome disassembly
|
GO:0006337 |
12 |
0.912
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.910
|
|
|
|
definitive erythrocyte differentiation
|
GO:0060318 |
2 |
0.907
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.887
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.885
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.883
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.863
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.713
|
|
|
|
protein dna complex disassembly
|
GO:0032986 |
12 |
0.705
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.583
|
Worm Fly |
|
|
nucleosome positioning
|
GO:0016584 |
3 |
0.578
|
|
|
|
nucleosome organization
|
GO:0034728 |
66 |
0.578
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.538
|
|
|
|
positive regulation of gene expression epigenetic
|
GO:0045815 |
7 |
0.532
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.500
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.477
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.418
|
|
|
|
chromatin disassembly
|
GO:0031498 |
13 |
0.403
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.353
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.313
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.297
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.294
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.280
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.271
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.267
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.266
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.259
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.254
|
Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.246
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.246
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.238
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.237
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.228
|
Fly |
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.227
|
|
|
|
pharyngeal system development
|
GO:0060037 |
2 |
0.223
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.222
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.219
|
|
|
|
chromatin mediated maintenance of transcription
|
GO:0048096 |
2 |
0.219
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.216
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.209
|
Fly |
|
|
chromatin remodeling at centromere
|
GO:0031055 |
2 |
0.205
|
|
|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.202
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.192
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.190
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.190
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.171
|
Worm |
|
|
protein acylation
|
GO:0043543 |
138 |
0.169
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.169
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.168
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.167
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.167
|
|
|
|
histone h3 k27 acetylation
|
GO:0043974 |
2 |
0.164
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.162
|
Fly |
|
|
regulation of single species biofilm formation
|
GO:1900190 |
2 |
0.158
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.156
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.153
|
|
|
|
positive regulation of chromatin assembly or disassembly
|
GO:0045799 |
2 |
0.152
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.151
|
Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.149
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.145
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.145
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.144
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.143
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.141
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.139
|
|
|
|
strand invasion
|
GO:0042148 |
2 |
0.139
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.138
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.131
|
Mouse Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.131
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.129
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.128
|
Yeast |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.122
|
|
|
|
positive regulation of epidermal growth factor receptor signaling pathway
|
GO:0045742 |
11 |
0.121
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.121
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.118
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.118
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.117
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.115
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.113
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.113
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.113
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.111
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.110
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.109
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.109
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.108
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.108
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.108
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.107
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.107
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.105
|
|
|
|
corticosteroid receptor signaling pathway
|
GO:0031958 |
5 |
0.105
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.103
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.103
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.102
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.099
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.096
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.095
|
Fly |
|
|
response to fatty acid
|
GO:0070542 |
13 |
0.094
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.093
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.093
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.092
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.091
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.090
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.090
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.090
|
Yeast |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.090
|
Yeast |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.087
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.086
|
Yeast |
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.086
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.085
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.085
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.084
|
|
|
|
atp dependent chromatin remodeling
|
GO:0043044 |
25 |
0.083
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.081
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.080
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.080
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.079
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.079
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
1 |
0.079
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.076
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.075
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.075
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.075
|
|
|
|
growth
|
GO:0040007 |
202 |
0.075
|
Yeast |
|
|
forebrain development
|
GO:0030900 |
26 |
0.072
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.072
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.071
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.071
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.071
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.070
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.069
|
Worm |
|
|
negative regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033144 |
18 |
0.069
|
|
|
|
oligosaccharide metabolic process
|
GO:0009311 |
13 |
0.068
|
Yeast |
|
|
thalamus development
|
GO:0021794 |
2 |
0.067
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.067
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.066
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.066
|
Yeast |
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.065
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.063
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.063
|
Worm |
|
|
brain morphogenesis
|
GO:0048854 |
1 |
0.062
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.062
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.062
|
Fly |
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.061
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.061
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.060
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.060
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.059
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.059
|
Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.059
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.059
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.058
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.058
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.057
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.057
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.057
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.057
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.056
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.056
|
Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.056
|
|
|
|
regulation of heterochromatin assembly
|
GO:0031445 |
1 |
0.055
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.055
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.055
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.055
|
Yeast |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.054
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.053
|
|
|
|
smooth muscle cell differentiation
|
GO:0051145 |
8 |
0.053
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.053
|
|
|
|
translation
|
GO:0006412 |
132 |
0.052
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.052
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.052
|
|
|
|
histone arginine methylation
|
GO:0034969 |
6 |
0.052
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.052
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.051
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.051
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.051
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.051
|
Yeast |
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.050
|
Fly |
|
|
dendrite development
|
GO:0016358 |
24 |
0.050
|
Fly |
|
|
system process
|
GO:0003008 |
349 |
0.049
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.049
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.049
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.049
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.049
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.048
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.048
|
Yeast |
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.048
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.048
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.047
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.047
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.047
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.046
|
Fly |
|
|
innate immune response
|
GO:0045087 |
178 |
0.046
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.046
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.045
|
|
|
|
positive regulation of cell fate commitment
|
GO:0010455 |
2 |
0.045
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.045
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.045
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.045
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.045
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.044
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.044
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.044
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.044
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.043
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.043
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.043
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.042
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.042
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.042
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.042
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.042
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.041
|
Yeast |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.041
|
Yeast |
|
|
striated muscle cell apoptotic process
|
GO:0010658 |
3 |
0.041
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.041
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.041
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.041
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.041
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.040
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.040
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.040
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.040
|
Yeast |
|
|
heart trabecula morphogenesis
|
GO:0061384 |
1 |
0.040
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.039
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.039
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.039
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.038
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.038
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.038
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.038
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.038
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.038
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.038
|
|
|
|
negative regulation of stem cell proliferation
|
GO:2000647 |
3 |
0.038
|
|
|
|
phospholipid catabolic process
|
GO:0009395 |
12 |
0.038
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.038
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.037
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.037
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.037
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.037
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.036
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.036
|
Worm |
|
|
definitive hemopoiesis
|
GO:0060216 |
2 |
0.036
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.036
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.036
|
|
|
|
trabecula formation
|
GO:0060343 |
1 |
0.036
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.036
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.036
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.036
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.036
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.035
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.035
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.035
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.035
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.035
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.035
|
|
|
|
regulation of cardiac muscle cell apoptotic process
|
GO:0010665 |
3 |
0.035
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.035
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.035
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.035
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.035
|
Yeast |
|
|
regulation of chromatin assembly
|
GO:0010847 |
2 |
0.035
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.034
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.034
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.033
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.033
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.033
|
Yeast |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.033
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.033
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.033
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.033
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.033
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.033
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.033
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.032
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.032
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.032
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.032
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.032
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.032
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.032
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.032
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.032
|
Yeast |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.032
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.031
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.031
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.031
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.031
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.031
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.031
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.031
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.031
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.031
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.031
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.030
|
|
|
|
behavioral fear response
|
GO:0001662 |
0 |
0.030
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.030
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.030
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.030
|
Yeast |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.030
|
Yeast |
|
|
mrna catabolic process
|
GO:0006402 |
56 |
0.030
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.030
|
|
|
|
heterochromatin assembly
|
GO:0031507 |
6 |
0.029
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.029
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.029
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.029
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.029
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.029
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.029
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.029
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.029
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.028
|
Worm |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.028
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.028
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.028
|
Worm |
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.028
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.028
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.028
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.028
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.027
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.027
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.027
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.027
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.027
|
Worm |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.027
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.027
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.027
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.027
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.027
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.027
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.026
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.026
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.026
|
Yeast |
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
1 |
0.026
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.026
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.026
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.026
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.026
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.026
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.026
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.026
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.026
|
|
|
|
response to testosterone
|
GO:0033574 |
1 |
0.025
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.025
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.025
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.025
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.025
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.025
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.025
|
Yeast |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.025
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.025
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.025
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.025
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.025
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.025
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.025
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.025
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.025
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.025
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.025
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.024
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.024
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.024
|
Yeast |
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.024
|
|
|
|
detection of mechanical stimulus
|
GO:0050982 |
4 |
0.024
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
1 |
0.024
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.024
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.024
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.024
|
Yeast |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.023
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.023
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.023
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.023
|
|
|
|
regulation of intracellular estrogen receptor signaling pathway
|
GO:0033146 |
13 |
0.023
|
|
|
|
negative regulation of striated muscle cell apoptotic process
|
GO:0010664 |
2 |
0.023
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.023
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.023
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.023
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.023
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.023
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.023
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.023
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.023
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.023
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.022
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.022
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.022
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.022
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.022
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.022
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.022
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.022
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.022
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.022
|
Worm |
|
|
base excision repair
|
GO:0006284 |
21 |
0.022
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.022
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.022
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.022
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.022
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.022
|
Yeast |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.022
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.022
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.022
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.022
|
|
|
|
positive regulation of heterochromatin assembly
|
GO:0031453 |
1 |
0.021
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.021
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.021
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.021
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.021
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.021
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.021
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.021
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.021
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.021
|
Fly |
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.021
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.021
|
|
|
|
negative regulation of cardiac muscle cell apoptotic process
|
GO:0010667 |
2 |
0.021
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.021
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.021
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.021
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.021
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.020
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.020
|
Yeast |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.020
|
Yeast |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.020
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.020
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.020
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.020
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.020
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.020
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.020
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.020
|
Yeast |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.020
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.020
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.020
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.020
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.019
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.019
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.019
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.019
|
|
|
|
glucocorticoid receptor signaling pathway
|
GO:0042921 |
5 |
0.019
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.019
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
3 |
0.019
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.019
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.019
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.019
|
Mouse |
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.019
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.019
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.019
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.019
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.019
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
8 |
0.019
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.018
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.018
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.018
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.018
|
|
|
|
alcohol catabolic process
|
GO:0046164 |
20 |
0.018
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.018
|
Yeast |
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.018
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.018
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.018
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.018
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.018
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.018
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.018
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.018
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.018
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.018
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.018
|
|
|
|
negative regulation of translation
|
GO:0017148 |
37 |
0.018
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.018
|
Yeast |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.018
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.018
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.018
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.018
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.017
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.017
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.017
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.017
|
Yeast |
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.017
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.017
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.017
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.017
|
|
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.017
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.017
|
|
