Homo sapiens

89 known processes

KDM4A

lysine (K)-specific demethylase 4A

(Aliases: JMJD2,JMJD2A,JHDM3A,KIAA0677)

KDM4A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin organization GO:0006325 351 0.285
chromatin modification GO:0016568 298 0.269
cellular response to dna damage stimulus GO:0006974 379 0.155
dna repair GO:0006281 198 0.151
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.134
Yeast
regulation of cell differentiation GO:0045595 393 0.132
Rat
histone h3 k79 methylation GO:0034729 2 0.130
dna replication dependent nucleosome assembly GO:0006335 32 0.126
dna replication dependent nucleosome organization GO:0034723 32 0.125
dna replication independent nucleosome organization GO:0034724 27 0.115
histone modification GO:0016570 251 0.113
covalent chromatin modification GO:0016569 254 0.113
anatomical structure formation involved in morphogenesis GO:0048646 284 0.107
nucleotide excision repair GO:0006289 31 0.101
regulation of cell cycle process GO:0010564 266 0.096
dna replication independent nucleosome assembly GO:0006336 27 0.093
modification dependent macromolecule catabolic process GO:0043632 212 0.084
histone methylation GO:0016571 60 0.082
regulation of proteolysis GO:0030162 293 0.079
myeloid cell differentiation GO:0030099 117 0.078
protein catabolic process GO:0030163 325 0.076
nucleosome organization GO:0034728 66 0.073
histone lysine methylation GO:0034968 50 0.071
ubiquitin dependent protein catabolic process GO:0006511 206 0.070
mitotic cell cycle phase transition GO:0044772 162 0.069
regulation of mitotic cell cycle phase transition GO:1901990 118 0.068
cellular macromolecule catabolic process GO:0044265 380 0.068
nucleosome assembly GO:0006334 50 0.067
post embryonic development GO:0009791 2 0.066
modification dependent protein catabolic process GO:0019941 209 0.065
regulation of mitotic cell cycle GO:0007346 189 0.064
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.063
regulation of cellular protein catabolic process GO:1903362 96 0.063
neuroblast proliferation GO:0007405 4 0.063
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.063
negative regulation of multicellular organismal process GO:0051241 317 0.061
Rat
negative regulation of myeloid cell differentiation GO:0045638 42 0.061
macromolecule methylation GO:0043414 97 0.061
regulation of cell cycle GO:0051726 393 0.057
protein alkylation GO:0008213 74 0.057
negative regulation of megakaryocyte differentiation GO:0045653 16 0.054
cell cycle checkpoint GO:0000075 117 0.053
cellular macromolecular complex assembly GO:0034622 324 0.051
negative regulation of cellular component organization GO:0051129 235 0.050
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.050
proteasomal protein catabolic process GO:0010498 176 0.050
mitotic cell cycle GO:0000278 326 0.050
negative regulation of cell cycle GO:0045786 193 0.050
histone acetylation GO:0016573 93 0.048
cell cycle phase transition GO:0044770 173 0.047
mitotic cell cycle process GO:1903047 286 0.046
chromatin assembly GO:0031497 61 0.046
peptidyl lysine modification GO:0018205 144 0.046
immune system development GO:0002520 195 0.045
negative regulation of chromosome organization GO:2001251 48 0.045
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.045
negative regulation of cellular protein metabolic process GO:0032269 353 0.044
negative regulation of developmental process GO:0051093 247 0.044
Rat
protein dna complex subunit organization GO:0071824 80 0.044
protein processing GO:0016485 226 0.044
protein dna complex assembly GO:0065004 64 0.043
negative regulation of cellular catabolic process GO:0031330 83 0.043
growth GO:0040007 202 0.042
multicellular organismal aging GO:0010259 3 0.042
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.041
regulation of cellular ketone metabolic process GO:0010565 50 0.041
oogenesis GO:0048477 2 0.041
protein maturation GO:0051604 233 0.041
nervous system development GO:0007399 293 0.038
Rat
negative regulation of organelle organization GO:0010639 126 0.037
negative regulation of proteolysis GO:0045861 132 0.037
regulation of proteasomal protein catabolic process GO:0061136 87 0.037
ribonucleoside triphosphate catabolic process GO:0009203 391 0.036
ras protein signal transduction GO:0007265 73 0.036
chromatin assembly or disassembly GO:0006333 78 0.036
negative regulation of cell cycle phase transition GO:1901988 89 0.035
internal protein amino acid acetylation GO:0006475 101 0.035
cellular amino acid metabolic process GO:0006520 116 0.035
negative regulation of immune system process GO:0002683 136 0.035
ribonucleoside catabolic process GO:0042454 406 0.034
cell projection organization GO:0030030 252 0.033
regulation of mitosis GO:0007088 63 0.033
negative regulation of protein maturation GO:1903318 142 0.033
purine ribonucleoside metabolic process GO:0046128 437 0.033
protein acetylation GO:0006473 116 0.032
regulation of protein catabolic process GO:0042176 155 0.032
dna conformation change GO:0071103 113 0.032
cell division GO:0051301 168 0.032
positive regulation of developmental process GO:0051094 314 0.031
Rat
regulation of chromosome segregation GO:0051983 44 0.031
negative regulation of cell cycle process GO:0010948 121 0.031
determination of adult lifespan GO:0008340 2 0.031
Worm
dna packaging GO:0006323 77 0.031
regulation of cell cycle phase transition GO:1901987 126 0.031
regulation of protein maturation GO:1903317 150 0.030
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.030
female gamete generation GO:0007292 2 0.029
locomotory behavior GO:0007626 1 0.029
regulation of myeloid cell differentiation GO:0045637 81 0.029
negative regulation of mitotic cell cycle GO:0045930 102 0.029
negative regulation of catabolic process GO:0009895 104 0.029
mitotic cell cycle checkpoint GO:0007093 68 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.027
organophosphate catabolic process GO:0046434 430 0.027
cellular protein catabolic process GO:0044257 261 0.027
protein modification by small protein conjugation GO:0032446 342 0.027
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
histone h4 acetylation GO:0043967 47 0.027
protein ubiquitination GO:0016567 314 0.026
cellular lipid metabolic process GO:0044255 303 0.026
Yeast
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
epithelial cell proliferation GO:0050673 128 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.026
small gtpase mediated signal transduction GO:0007264 78 0.026
negative regulation of protein processing GO:0010955 142 0.025
nucleotide catabolic process GO:0009166 408 0.025
lipid metabolic process GO:0006629 381 0.025
Yeast
cellular component morphogenesis GO:0032989 314 0.025
negative regulation of cellular protein catabolic process GO:1903363 38 0.025
memory GO:0007613 3 0.025
chromosome segregation GO:0007059 114 0.025
regulation of protein processing GO:0070613 150 0.025
nucleoside triphosphate metabolic process GO:0009141 422 0.025
regulation of sister chromatid segregation GO:0033045 27 0.025
carbohydrate metabolic process GO:0005975 207 0.024
nucleoside catabolic process GO:0009164 408 0.024
reproductive process GO:0022414 106 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
Human
positive regulation of catabolic process GO:0009896 310 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
purine containing compound catabolic process GO:0072523 411 0.023
regulation of nuclear division GO:0051783 65 0.023
hematopoietic or lymphoid organ development GO:0048534 186 0.023
morphogenesis of embryonic epithelium GO:0016331 4 0.023
positive regulation of hydrolase activity GO:0051345 331 0.023
thalamus development GO:0021794 2 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
response to oxygen containing compound GO:1901700 369 0.023
segmentation GO:0035282 4 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
developmental process involved in reproduction GO:0003006 66 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
negative regulation of protein catabolic process GO:0042177 59 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
cellular ketone metabolic process GO:0042180 80 0.022
mitotic sister chromatid separation GO:0051306 18 0.022
negative regulation of cell proliferation GO:0008285 228 0.022
monocarboxylic acid metabolic process GO:0032787 185 0.022
sister chromatid segregation GO:0000819 54 0.022
adult locomotory behavior GO:0008344 1 0.022
neuromuscular junction development GO:0007528 3 0.022
cytoplasmic transport GO:0016482 379 0.022
megakaryocyte differentiation GO:0030219 25 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
single organism cellular localization GO:1902580 332 0.021
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.021
cell morphogenesis GO:0000902 296 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
regeneration GO:0031099 4 0.021
single organism reproductive process GO:0044702 98 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.020
regulation of cellular response to stress GO:0080135 244 0.020
regulation of chromosome organization GO:0033044 103 0.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.020
response to cytokine GO:0034097 232 0.020
mitotic nuclear division GO:0007067 119 0.020
maintenance of location GO:0051235 112 0.020
hematopoietic progenitor cell differentiation GO:0002244 38 0.020
protein localization to organelle GO:0033365 280 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.019
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.019
negative regulation of cell differentiation GO:0045596 171 0.019
Rat
peripheral nervous system development GO:0007422 2 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
hindbrain development GO:0030902 3 0.019
hemopoiesis GO:0030097 180 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
regulation of cell division GO:0051302 116 0.019
system process GO:0003008 349 0.019
Mouse
primary neural tube formation GO:0014020 3 0.019
cell development GO:0048468 328 0.019
Rat
rho protein signal transduction GO:0007266 26 0.019
neurogenesis GO:0022008 169 0.019
Rat
photoreceptor cell differentiation GO:0046530 2 0.018
neural tube formation GO:0001841 3 0.018
blastoderm segmentation GO:0007350 2 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
neuron differentiation GO:0030182 138 0.018
Rat
amine metabolic process GO:0009308 44 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
epithelium development GO:0060429 227 0.018
associative learning GO:0008306 1 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
protein deubiquitination GO:0016579 79 0.017
positive regulation of cell death GO:0010942 263 0.017
regulation of growth GO:0040008 165 0.017
gene silencing GO:0016458 49 0.017
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.017
regulation of epithelial cell proliferation GO:0050678 113 0.017
guanosine containing compound metabolic process GO:1901068 244 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
negative regulation of hematopoietic progenitor cell differentiation GO:1901533 18 0.017
regulation of nucleotide catabolic process GO:0030811 205 0.017
regulation of protein localization GO:0032880 296 0.017
regulation of mitotic sister chromatid separation GO:0010965 27 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
positive regulation of transport GO:0051050 336 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
regulation of intracellular transport GO:0032386 195 0.016
regulation of cellular component movement GO:0051270 334 0.016
nerve development GO:0021675 4 0.016
protein targeting GO:0006605 187 0.016
single organism membrane organization GO:0044802 268 0.016
spindle checkpoint GO:0031577 26 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
negative regulation of cell death GO:0060548 345 0.016
Rat
spermatid differentiation GO:0048515 4 0.016
mitotic sister chromatid segregation GO:0000070 53 0.016
cell growth GO:0016049 160 0.016
metaphase anaphase transition of cell cycle GO:0044784 21 0.016
regulation of mitotic sister chromatid segregation GO:0033047 27 0.016
regulation of transferase activity GO:0051338 355 0.016
cation transport GO:0006812 331 0.016
circadian behavior GO:0048512 2 0.015
dephosphorylation GO:0016311 209 0.015
positive regulation of cell growth GO:0030307 48 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
innate immune response GO:0045087 178 0.015
regulation of dna metabolic process GO:0051052 153 0.015
intracellular protein transport GO:0006886 270 0.015
motor neuron axon guidance GO:0008045 2 0.015
regulation of mapk cascade GO:0043408 262 0.015
generation of neurons GO:0048699 152 0.015
Rat
gtp metabolic process GO:0046039 239 0.015
nitrogen compound transport GO:0071705 191 0.015
gtp catabolic process GO:0006184 237 0.015
regulation of cell migration GO:0030334 289 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.015
positive regulation of organelle organization GO:0010638 195 0.015
neurological system process GO:0050877 163 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
rna processing GO:0006396 255 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
regulation of protein transport GO:0051223 213 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
chemical homeostasis GO:0048878 306 0.015
rhythmic behavior GO:0007622 2 0.015
regulation of gene silencing GO:0060968 24 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
internal peptidyl lysine acetylation GO:0018393 97 0.015
organ formation GO:0048645 3 0.015
nuclear transport GO:0051169 179 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
multi organism reproductive process GO:0044703 54 0.015
double strand break repair GO:0006302 101 0.015
regulation of ras protein signal transduction GO:0046578 155 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
regulation of gtpase activity GO:0043087 180 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
methylation GO:0032259 106 0.014
regulation of locomotion GO:0040012 329 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
cell part morphogenesis GO:0032990 137 0.014
endomembrane system organization GO:0010256 196 0.014
cellular amine metabolic process GO:0044106 41 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
protein modification by small protein removal GO:0070646 92 0.014
vesicle mediated transport GO:0016192 371 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
protein localization to membrane GO:0072657 160 0.014
anterior posterior axis specification GO:0009948 2 0.014
spermatid development GO:0007286 4 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
oxidation reduction process GO:0055114 396 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
cell fate determination GO:0001709 3 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
i kappab kinase nf kappab signaling GO:0007249 166 0.014
regulation of protein ubiquitination GO:0031396 95 0.014
organelle assembly GO:0070925 176 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
recombinational repair GO:0000725 50 0.014
membrane organization GO:0061024 292 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
apoptotic signaling pathway GO:0097190 268 0.014
immune response GO:0006955 307 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
tripartite regional subdivision GO:0007351 2 0.014
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.014
actin filament based process GO:0030029 224 0.014
small molecule biosynthetic process GO:0044283 157 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
regulation of cell growth GO:0001558 135 0.014
negative regulation of protein modification process GO:0031400 200 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.013
inner ear morphogenesis GO:0042472 4 0.013
neural tube closure GO:0001843 3 0.013
embryo development GO:0009790 123 0.013
cell adhesion GO:0007155 325 0.013
oocyte development GO:0048599 1 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
microtubule based process GO:0007017 210 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
reproduction GO:0000003 63 0.013
nuclear division GO:0000280 128 0.013
limbic system development GO:0021761 3 0.013
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.013
biological adhesion GO:0022610 331 0.013
regulation of response to external stimulus GO:0032101 222 0.013
regulation of kinase activity GO:0043549 314 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
establishment of planar polarity GO:0001736 3 0.013
glycerolipid metabolic process GO:0046486 107 0.013
transmembrane transport GO:0055085 399 0.013
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
regulation of protein kinase activity GO:0045859 289 0.013
mapk cascade GO:0000165 288 0.013
compound eye development GO:0048749 1 0.013
morphogenesis of a polarized epithelium GO:0001738 3 0.012
ion transmembrane transport GO:0034220 338 0.012
negative regulation of mitosis GO:0045839 24 0.012
viral life cycle GO:0019058 132 0.012
fatty acid metabolic process GO:0006631 115 0.012
tube closure GO:0060606 3 0.012
response to abiotic stimulus GO:0009628 336 0.012
secretion by cell GO:0032940 226 0.012
cell projection morphogenesis GO:0048858 129 0.012
regulation of cell motility GO:2000145 299 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
Rat
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.012
double strand break repair via homologous recombination GO:0000724 50 0.012
mitotic spindle checkpoint GO:0071174 18 0.012
organelle fission GO:0048285 149 0.012
negative regulation of gliogenesis GO:0014014 3 0.012
Rat
regulation of endopeptidase activity GO:0052548 170 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
visual behavior GO:0007632 2 0.012
cation transmembrane transport GO:0098655 238 0.012
regulation of gene expression epigenetic GO:0040029 73 0.012
regulation of multi organism process GO:0043900 157 0.012
regulation of cell development GO:0060284 161 0.012
Rat
anion transport GO:0006820 161 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
demethylation GO:0070988 37 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
salivary gland morphogenesis GO:0007435 4 0.012
response to axon injury GO:0048678 1 0.012
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.011
regulation of cytokine production GO:0001817 232 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
anatomical structure homeostasis GO:0060249 100 0.011
nuclear import GO:0051170 106 0.011
regulation of immune response GO:0050776 201 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
dna integrity checkpoint GO:0031570 71 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
forebrain generation of neurons GO:0021872 3 0.011
behavior GO:0007610 112 0.011
multi organism cellular process GO:0044764 156 0.011
Yeast
positive regulation of gtpase activity GO:0043547 166 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
tissue regeneration GO:0042246 3 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
metal ion transport GO:0030001 272 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.011
sensory perception of pain GO:0019233 4 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
regulation of response to dna damage stimulus GO:2001020 94 0.011
regulation of secretion by cell GO:1903530 177 0.011
rna interference GO:0016246 4 0.011
cerebellum development GO:0021549 2 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
protein autophosphorylation GO:0046777 123 0.011
cellular protein complex assembly GO:0043623 188 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
interspecies interaction between organisms GO:0044419 156 0.011
defense response GO:0006952 315 0.011
thymus development GO:0048538 3 0.011
forebrain neuron differentiation GO:0021879 3 0.011
regulation of secretion GO:0051046 194 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
Yeast
oocyte differentiation GO:0009994 2 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
cell projection assembly GO:0030031 126 0.011
sequestering of metal ion GO:0051238 24 0.011
neuron projection development GO:0031175 106 0.011
positive regulation of proteolysis GO:0045862 142 0.011
circulatory system development GO:0072359 262 0.011
cation homeostasis GO:0055080 189 0.011
positive regulation of transferase activity GO:0051347 227 0.011
spinal cord development GO:0021510 4 0.011
monosaccharide metabolic process GO:0005996 74 0.011
regulation of binding GO:0051098 111 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
regulation of cell projection organization GO:0031344 107 0.010
mating GO:0007618 1 0.010
regulation of peptidase activity GO:0052547 180 0.010
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.010
protein oligomerization GO:0051259 173 0.010
nucleus localization GO:0051647 1 0.010
sexual reproduction GO:0019953 37 0.010
organic acid biosynthetic process GO:0016053 97 0.010
actin mediated cell contraction GO:0070252 12 0.010
response to nitrogen compound GO:1901698 184 0.010
neurotransmitter secretion GO:0007269 4 0.010
spindle assembly checkpoint GO:0071173 17 0.010
mitochondrion organization GO:0007005 156 0.010
cellular response to external stimulus GO:0071496 111 0.010
neuron remodeling GO:0016322 2 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010
positive regulation of kinase activity GO:0033674 204 0.010
positive regulation of immune system process GO:0002684 283 0.010
cellular homeostasis GO:0019725 196 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
positive regulation of protein phosphorylation GO:0001934 313 0.010
lipid catabolic process GO:0016042 84 0.010
endosomal transport GO:0016197 129 0.010
skeletal system development GO:0001501 79 0.010
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.010

KDM4A disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.029
musculoskeletal system disease DOID:17 223 0.024
inherited metabolic disorder DOID:655 242 0.022
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020
disease of cellular proliferation DOID:14566 174 0.018
cancer DOID:162 167 0.018
organ system cancer DOID:0050686 164 0.018
sensory system disease DOID:0050155 203 0.018
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015
bone disease DOID:0080001 88 0.014
connective tissue disease DOID:65 109 0.014
retinal disease DOID:5679 118 0.013
immune system disease DOID:2914 155 0.013
muscular disease DOID:0080000 114 0.013
muscle tissue disease DOID:66 113 0.013
myopathy DOID:423 104 0.012
neurodegenerative disease DOID:1289 102 0.012
brain disease DOID:936 73 0.011
retinal degeneration DOID:8466 89 0.011