Homo sapiens

79 known processes

MED17

mediator complex subunit 17

(Aliases: CRSP6,TRAP80,FLJ10812,CRSP77,DRIP80)

MED17 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.460
post embryonic development GO:0009791 2 0.310
defense response GO:0006952 315 0.242
regulation of cell cycle GO:0051726 393 0.160
Fly
regulation of neural precursor cell proliferation GO:2000177 4 0.119
nervous system development GO:0007399 293 0.117
regulation of transferase activity GO:0051338 355 0.112
regulation of cell cycle process GO:0010564 266 0.107
Fly
rna processing GO:0006396 255 0.098
negative regulation of cell proliferation GO:0008285 228 0.097
dna templated transcription initiation GO:0006352 35 0.093
regulation of cellular amine metabolic process GO:0033238 11 0.089
neuroblast proliferation GO:0007405 4 0.088
negative regulation of multicellular organismal process GO:0051241 317 0.087
oogenesis GO:0048477 2 0.085
cellular amine metabolic process GO:0044106 41 0.080
female gamete generation GO:0007292 2 0.071
rna 3 end processing GO:0031123 35 0.070
neurogenesis GO:0022008 169 0.070
mrna metabolic process GO:0016071 175 0.070
cellular ketone metabolic process GO:0042180 80 0.068
regulation of neuroblast proliferation GO:1902692 3 0.066
cellular amino acid metabolic process GO:0006520 116 0.063
histone modification GO:0016570 251 0.055
regulation of kinase activity GO:0043549 314 0.054
innate immune response GO:0045087 178 0.051
chromatin organization GO:0006325 351 0.050
cellular macromolecule catabolic process GO:0044265 380 0.049
immune response GO:0006955 307 0.048
determination of adult lifespan GO:0008340 2 0.047
response to external biotic stimulus GO:0043207 261 0.046
rna splicing GO:0008380 131 0.045
negative regulation of cell differentiation GO:0045596 171 0.045
blastocyst development GO:0001824 3 0.044
generation of neurons GO:0048699 152 0.043
defense response to other organism GO:0098542 129 0.043
cell development GO:0048468 328 0.042
negative regulation of developmental process GO:0051093 247 0.040
regulation of cell development GO:0060284 161 0.040
multicellular organismal aging GO:0010259 3 0.039
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
defense response to bacterium GO:0042742 63 0.038
regulation of protein kinase activity GO:0045859 289 0.037
covalent chromatin modification GO:0016569 254 0.036
vesicle mediated transport GO:0016192 371 0.035
negative regulation of kinase activity GO:0033673 106 0.034
response to other organism GO:0051707 261 0.034
regulation of cell differentiation GO:0045595 393 0.034
negative regulation of cell cycle phase transition GO:1901988 89 0.034
Fly
mitotic cell cycle process GO:1903047 286 0.033
Fly
internal protein amino acid acetylation GO:0006475 101 0.032
negative regulation of phosphorylation GO:0042326 174 0.031
chromatin modification GO:0016568 298 0.030
mitotic cell cycle GO:0000278 326 0.030
Fly
single organism reproductive process GO:0044702 98 0.030
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.029
endocytosis GO:0006897 159 0.029
enzyme linked receptor protein signaling pathway GO:0007167 303 0.028
ncrna metabolic process GO:0034660 108 0.028
regulation of growth GO:0040008 165 0.028
negative regulation of cell development GO:0010721 48 0.028
peptidyl lysine modification GO:0018205 144 0.027
protein catabolic process GO:0030163 325 0.026
cytoplasmic transport GO:0016482 379 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
reproductive system development GO:0061458 56 0.026
regulation of cellular ketone metabolic process GO:0010565 50 0.026
mrna processing GO:0006397 133 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
response to biotic stimulus GO:0009607 276 0.026
internal peptidyl lysine acetylation GO:0018393 97 0.025
negative regulation of phosphorus metabolic process GO:0010563 267 0.025
positive regulation of immune system process GO:0002684 283 0.025
receptor mediated endocytosis GO:0006898 84 0.025
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.025
macromolecule methylation GO:0043414 97 0.024
rna interference GO:0016246 4 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
amine metabolic process GO:0009308 44 0.024
protein modification by small protein conjugation GO:0032446 342 0.023
memory GO:0007613 3 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
neuron development GO:0048666 113 0.023
mitotic cell cycle phase transition GO:0044772 162 0.023
Fly
lipid metabolic process GO:0006629 381 0.023
embryo development GO:0009790 123 0.022
cellular component morphogenesis GO:0032989 314 0.022
negative regulation of immune system process GO:0002683 136 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
organelle assembly GO:0070925 176 0.021
dephosphorylation GO:0016311 209 0.021
cell cycle phase transition GO:0044770 173 0.021
Fly
immune system development GO:0002520 195 0.021
regulation of mapk cascade GO:0043408 262 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
ncrna processing GO:0034470 83 0.020
positive regulation of phosphorylation GO:0042327 394 0.020
neural tube formation GO:0001841 3 0.020
regulation of protein serine threonine kinase activity GO:0071900 179 0.019
neuron differentiation GO:0030182 138 0.019
response to growth factor GO:0070848 205 0.019
dna replication GO:0006260 116 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
cell projection morphogenesis GO:0048858 129 0.018
regulation of defense response GO:0031347 154 0.018
positive regulation of transport GO:0051050 336 0.018
growth GO:0040007 202 0.018
negative regulation of protein modification process GO:0031400 200 0.018
regulation of protein localization GO:0032880 296 0.018
regulation of meiotic cell cycle GO:0051445 4 0.018
neuron projection development GO:0031175 106 0.018
negative regulation of cell cycle GO:0045786 193 0.018
Fly
regulation of mitotic cell cycle phase transition GO:1901990 118 0.017
Fly
positive regulation of developmental process GO:0051094 314 0.017
negative regulation of neurogenesis GO:0050768 26 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
regulation of intracellular transport GO:0032386 195 0.016
mapk cascade GO:0000165 288 0.016
microtubule based process GO:0007017 210 0.016
regulation of chromosome organization GO:0033044 103 0.016
protein localization to organelle GO:0033365 280 0.016
muscle structure development GO:0061061 98 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
protein dna complex assembly GO:0065004 64 0.016
intrinsic apoptotic signaling pathway GO:0097193 127 0.016
sex differentiation GO:0007548 45 0.016
regulation of meiosis GO:0040020 3 0.015
negative regulation of protein kinase activity GO:0006469 98 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
positive regulation of innate immune response GO:0045089 79 0.015
positive regulation of cell death GO:0010942 263 0.015
methylation GO:0032259 106 0.015
regulation of neurogenesis GO:0050767 82 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
spermatid development GO:0007286 4 0.015
regulation of secretion GO:0051046 194 0.015
cellular protein complex assembly GO:0043623 188 0.015
protein dna complex subunit organization GO:0071824 80 0.014
multi organism reproductive process GO:0044703 54 0.014
protein oligomerization GO:0051259 173 0.014
long term memory GO:0007616 2 0.014
regulation of dna metabolic process GO:0051052 153 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
cell projection organization GO:0030030 252 0.014
negative regulation of mapk cascade GO:0043409 56 0.014
developmental process involved in reproduction GO:0003006 66 0.014
peptidyl lysine acetylation GO:0018394 101 0.014
cellular response to lipid GO:0071396 127 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
positive regulation of defense response GO:0031349 87 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
Fly
cellular response to endogenous stimulus GO:0071495 336 0.014
androgen receptor signaling pathway GO:0030521 34 0.014
maintenance of location GO:0051235 112 0.013
negative regulation of cell death GO:0060548 345 0.013
reproductive structure development GO:0048608 55 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
hemopoiesis GO:0030097 180 0.013
regulation of immune response GO:0050776 201 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
protein alkylation GO:0008213 74 0.013
negative regulation of neural precursor cell proliferation GO:2000178 1 0.013
regulation of binding GO:0051098 111 0.013
protein ubiquitination GO:0016567 314 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
metencephalon development GO:0022037 2 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
secretion GO:0046903 254 0.012
hindbrain development GO:0030902 3 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
reproductive process GO:0022414 106 0.012
response to bacterium GO:0009617 144 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
ncrna 3 end processing GO:0043628 4 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
lens development in camera type eye GO:0002088 2 0.012
negative regulation of stem cell proliferation GO:2000647 3 0.012
rna splicing via transesterification reactions GO:0000375 90 0.012
response to abiotic stimulus GO:0009628 336 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
nitrogen compound transport GO:0071705 191 0.012
stem cell division GO:0017145 2 0.011
histone acetylation GO:0016573 93 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.011
Fly
negative regulation of growth GO:0045926 97 0.011
chemotaxis GO:0006935 157 0.011
gonad development GO:0008406 34 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
circulatory system development GO:0072359 262 0.011
myosin filament organization GO:0031033 2 0.011
positive regulation of immune response GO:0050778 159 0.011
cell cycle checkpoint GO:0000075 117 0.011
Fly
regulation of cell activation GO:0050865 125 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
actomyosin structure organization GO:0031032 59 0.011
mrna splicing via spliceosome GO:0000398 89 0.011
regulation of cytokine production GO:0001817 232 0.011
histone lysine methylation GO:0034968 50 0.011
protein localization to nucleus GO:0034504 136 0.011
cell cycle g1 s phase transition GO:0044843 80 0.011
cell division GO:0051301 168 0.011
neuromuscular junction development GO:0007528 3 0.011
blood vessel morphogenesis GO:0048514 162 0.010
regulation of nervous system development GO:0051960 88 0.010
apoptotic signaling pathway GO:0097190 268 0.010
protein acetylation GO:0006473 116 0.010
development of primary sexual characteristics GO:0045137 35 0.010
protein homooligomerization GO:0051260 100 0.010
embryo development ending in birth or egg hatching GO:0009792 34 0.010
regulation of leukocyte activation GO:0002694 115 0.010
regulation of protein stability GO:0031647 87 0.010
proteasomal protein catabolic process GO:0010498 176 0.010
histone methylation GO:0016571 60 0.010
negative regulation of hydrolase activity GO:0051346 182 0.010
regulation of mitotic cell cycle GO:0007346 189 0.010
Fly
myosin filament assembly GO:0031034 2 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010

MED17 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
sensory system disease DOID:0050155 203 0.017
eye and adnexa disease DOID:1492 150 0.017
nervous system disease DOID:863 431 0.017
eye disease DOID:5614 149 0.012