|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.387
|
Human Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.360
|
Human |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.308
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.285
|
Human Yeast Mouse Worm Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.275
|
Human Rat |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.272
|
Human Mouse |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.261
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.255
|
Human Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.243
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.218
|
Yeast |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.217
|
Human Rat |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.187
|
Human Zebrafish |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.186
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.181
|
Human Yeast Mouse Worm Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.180
|
Mouse Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.180
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.176
|
Worm Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.160
|
Human |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.153
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.149
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.149
|
Worm Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.145
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.143
|
Human Worm |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.142
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.142
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.139
|
Human Rat Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.139
|
Human Yeast Mouse Worm Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.138
|
Human Yeast Mouse Worm Fly |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.135
|
Human Worm |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.135
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.134
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.134
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.130
|
Human |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.130
|
Human |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.126
|
Fly |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.126
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.125
|
Human Rat |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.121
|
Human Yeast Mouse Worm Fly |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.121
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.120
|
Human Yeast Mouse Worm Fly |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.119
|
Human |
|
|
growth
|
GO:0040007 |
202 |
0.117
|
Yeast Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.114
|
Human Rat Fly |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.111
|
Human Worm |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.110
|
Human |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.110
|
Human |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.108
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.108
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.108
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.108
|
Worm Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.107
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.106
|
Human Worm |
|
|
immune system development
|
GO:0002520 |
195 |
0.106
|
Human Zebrafish Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.104
|
Human Worm |
|
|
cation transport
|
GO:0006812 |
331 |
0.104
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.103
|
Human Rat |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.101
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.101
|
Human |
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.101
|
Yeast |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.100
|
Human Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.100
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.099
|
Human Rat |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.099
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.098
|
Human Yeast Mouse Worm Fly |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.098
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.097
|
Human Yeast Mouse Worm Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.097
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.096
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.096
|
Human |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.095
|
Human |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.095
|
Human |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.094
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.094
|
Human Yeast Mouse Worm Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.094
|
Human Worm Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.093
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.090
|
Human Rat Fly |
|
|
ossification
|
GO:0001503 |
121 |
0.088
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.088
|
Human Rat |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.083
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.083
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.083
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.083
|
Human Rat |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.082
|
Human |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.081
|
Rat |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.081
|
Human Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.080
|
Human |
|
|
muscle contraction
|
GO:0006936 |
73 |
0.079
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.079
|
Mouse Fly |
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.078
|
Yeast |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.078
|
Human Worm |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.078
|
Human Yeast Mouse Worm Fly |
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.077
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.075
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.074
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.074
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.073
|
Human Yeast Fly |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.073
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.073
|
Human Yeast Mouse Worm Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.073
|
Human Yeast Mouse Worm Fly |
|
|
secretion
|
GO:0046903 |
254 |
0.072
|
Human Worm |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.072
|
Mouse |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.070
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.070
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.070
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.069
|
Yeast |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.069
|
Human Worm |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.068
|
Human Rat |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.068
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.067
|
Human |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.067
|
Human Worm |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.066
|
Human Rat |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.066
|
Human Yeast Mouse Worm Fly |
|
|
cell growth
|
GO:0016049 |
160 |
0.066
|
Yeast Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.066
|
Zebrafish Worm Fly |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.066
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.065
|
Human Zebrafish |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.065
|
Human |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.065
|
Human Yeast Mouse Worm Fly |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.065
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.064
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.064
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.064
|
Human Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.063
|
Human Worm |
|
|
associative learning
|
GO:0008306 |
1 |
0.063
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.062
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.062
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.062
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.061
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.061
|
Yeast |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.061
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.061
|
Human Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.061
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.060
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.059
|
Human |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.058
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.058
|
Human Rat Fly |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.058
|
Human Worm |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.058
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.058
|
Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.057
|
Human |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.056
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.055
|
Human Worm |
|
|
cell development
|
GO:0048468 |
328 |
0.055
|
Yeast Worm Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.055
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.054
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.054
|
|
|
|
system process
|
GO:0003008 |
349 |
0.054
|
Mouse |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.053
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.053
|
Yeast |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.053
|
Human |
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.053
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.051
|
Human |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.051
|
Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.049
|
Human Mouse Worm |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.049
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.049
|
Mouse Fly |
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.049
|
Human |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.048
|
Human Worm |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.048
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.048
|
Mouse Worm Fly |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.048
|
Human |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.048
|
Yeast |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.047
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.047
|
Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.046
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.046
|
Fly |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.046
|
Human |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.045
|
Worm |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.045
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.045
|
Human |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.045
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.045
|
Fly |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.044
|
Human Worm |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.044
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.043
|
Worm |
|
|
protein processing
|
GO:0016485 |
226 |
0.043
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.043
|
Human Worm |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.043
|
Human |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.043
|
Yeast |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.043
|
Human |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.042
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.042
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.042
|
Worm |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.042
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.042
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.042
|
Human Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.041
|
|
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.041
|
Yeast |
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.041
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.041
|
Yeast |
|
|
response to radiation
|
GO:0009314 |
151 |
0.041
|
Mouse |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.040
|
Human Yeast Mouse Worm Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.040
|
Mouse Worm Fly |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.040
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.040
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.040
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.040
|
Human |
|
|
muscle system process
|
GO:0003012 |
81 |
0.040
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.039
|
Human Yeast Worm |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.038
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.038
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.038
|
Human Yeast Mouse Worm Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.037
|
Fly |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.037
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.037
|
Human |
|
|
rna splicing
|
GO:0008380 |
131 |
0.037
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.036
|
Human Rat |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.036
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.036
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.035
|
Mouse Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.035
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.035
|
Fly |
|
|
exocytosis
|
GO:0006887 |
71 |
0.035
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.035
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.035
|
Mouse |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.035
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.035
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.035
|
Fly |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.034
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.034
|
Yeast Worm Fly |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.034
|
Yeast |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.034
|
Human Mouse Worm |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.034
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.034
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.034
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.034
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.033
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.033
|
Human |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.033
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.033
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.033
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.033
|
Fly |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.032
|
Yeast |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.032
|
Human Worm |
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.032
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.032
|
Human Yeast Mouse Worm Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.032
|
Human Yeast Worm |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.032
|
Human Yeast Mouse Worm Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.032
|
Human Yeast Mouse Worm Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.032
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.032
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.032
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.032
|
Human Yeast Mouse Worm Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.032
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.031
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.031
|
Mouse |
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.031
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.031
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.031
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.031
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.031
|
Mouse |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.030
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.030
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.030
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.030
|
Fly |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.030
|
Yeast |
|
|
neuron development
|
GO:0048666 |
113 |
0.030
|
Fly |
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.030
|
Yeast Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.030
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.030
|
Yeast Fly |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.030
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.029
|
Worm |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.029
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.029
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.029
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.029
|
Human |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.029
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.029
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.028
|
Worm |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.028
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.028
|
Fly |
|
|
response to hormone
|
GO:0009725 |
175 |
0.028
|
Rat |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.028
|
Human Worm |
|
|
wound healing
|
GO:0042060 |
115 |
0.028
|
Human |
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.028
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.028
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.028
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.028
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.028
|
Human |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.027
|
Zebrafish Worm |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.027
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.027
|
Human Yeast Worm |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.027
|
Fly |
|
|
neuron death
|
GO:0070997 |
65 |
0.027
|
Human Mouse |
|
|
oocyte development
|
GO:0048599 |
1 |
0.027
|
Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.027
|
Human Yeast Mouse Worm Fly |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.027
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.027
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.026
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.026
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.026
|
Human Worm |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.026
|
Human |
|
|
stem cell development
|
GO:0048864 |
69 |
0.026
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.026
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.026
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.026
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.026
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.025
|
Yeast |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.025
|
|
|
|
aging
|
GO:0007568 |
66 |
0.025
|
Human Yeast |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.025
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.025
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.025
|
Fly |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.025
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.025
|
Mouse Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.025
|
Human Yeast Mouse Worm Fly |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.024
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.024
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.024
|
Yeast |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.024
|
|
|
|
head development
|
GO:0060322 |
108 |
0.024
|
Human |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.024
|
Human Worm |
|
|
immune response
|
GO:0006955 |
307 |
0.024
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.024
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.023
|
Yeast |
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.023
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.023
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.023
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.023
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.023
|
Zebrafish |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.023
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
15 |
0.023
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.023
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.022
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.022
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.022
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.022
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.022
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.022
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.022
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.022
|
Human |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.022
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.022
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.022
|
Yeast |
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.022
|
Human |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.022
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.022
|
Human Yeast Mouse Worm Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.022
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.022
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.021
|
Human Yeast Mouse Worm Fly |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.021
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.021
|
Rat |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.021
|
Human |
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.021
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.021
|
Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.021
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.021
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.021
|
Yeast Worm Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.021
|
Fly |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.021
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.021
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.020
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.020
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.020
|
Fly |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.020
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.020
|
Fly |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.020
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.020
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.020
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.019
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.019
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.019
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.019
|
Human |
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.019
|
Yeast |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.019
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.019
|
Rat |
|
|
cell aging
|
GO:0007569 |
52 |
0.019
|
Human Yeast |
|
|
endocytosis
|
GO:0006897 |
159 |
0.019
|
Worm |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.019
|
Human |
|
|
protein import
|
GO:0017038 |
130 |
0.019
|
Fly |
|
|
nuclear import
|
GO:0051170 |
106 |
0.019
|
Fly |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.019
|
Human Worm |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.019
|
Fly |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.019
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.019
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.019
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.019
|
Mouse Fly |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.019
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.019
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.018
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.018
|
|
|
|
ribosome biogenesis
|
GO:0042254 |
48 |
0.018
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.018
|
Fly |
|
|
neurological system process
|
GO:0050877 |
163 |
0.018
|
Mouse |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.018
|
Human |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.018
|
Yeast Worm Fly |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.018
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.018
|
Yeast Fly |
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.018
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.018
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.018
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.018
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.018
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.018
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.018
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.018
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.018
|
Fly |
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.018
|
Yeast |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.018
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.018
|
Yeast |
|
|
behavior
|
GO:0007610 |
112 |
0.018
|
Mouse Rat |
|
|
signal release
|
GO:0023061 |
70 |
0.018
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.017
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.017
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.017
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.017
|
Yeast |
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.017
|
Yeast Fly |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.017
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.017
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.017
|
Human |
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.017
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.017
|
Mouse Fly |
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.017
|
Yeast |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.017
|
Fly |
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.017
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.017
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.017
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.017
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.017
|
Human Yeast Mouse Worm Fly |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.017
|
Fly |
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.017
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.017
|
Yeast |
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.017
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.017
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.017
|
Yeast |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.016
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.016
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.016
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.016
|
Fly |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.016
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.016
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.016
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.016
|
Worm Fly |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.016
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.016
|
Zebrafish Fly |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.016
|
Human |
|
|
regionalization
|
GO:0003002 |
29 |
0.016
|
Fly |
|
|
heart development
|
GO:0007507 |
95 |
0.016
|
Zebrafish |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.016
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.016
|
Fly |
|
|
response to lipid
|
GO:0033993 |
206 |
0.016
|
Rat |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.016
|
Human |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.016
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.016
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.016
|
Human |
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.016
|
Yeast Fly |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.016
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.016
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.016
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.016
|
Worm |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.015
|
Human Zebrafish Fly |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.015
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.015
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.015
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.015
|
Fly |
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.015
|
Fly |
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.015
|
Mouse |
|
|
methylation
|
GO:0032259 |
106 |
0.015
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.015
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.015
|
Human |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.015
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.015
|
Human Mouse |
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.015
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.015
|
Fly |
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.015
|
Human |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.015
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.015
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.015
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.015
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.015
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.015
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.015
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.015
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.015
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.014
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.014
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.014
|
Human |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.014
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.014
|
Fly |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.014
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.014
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.014
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.014
|
Human |
|
|
platelet activation
|
GO:0030168 |
44 |
0.014
|
|
