Homo sapiens

0 known processes

SPO11

SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)

(Aliases: MGC39953,CT35)

SPO11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 80 0.100
regulation of cellular amino acid metabolic process GO:0006521 6 0.090
cellular amine metabolic process GO:0044106 41 0.082
post embryonic development GO:0009791 2 0.077
positive regulation of cellular amine metabolic process GO:0033240 7 0.076
regulation of cellular amine metabolic process GO:0033238 11 0.076
regulation of cellular ketone metabolic process GO:0010565 50 0.075
cellular amino acid metabolic process GO:0006520 116 0.075
amine metabolic process GO:0009308 44 0.060
positive regulation of peptidyl serine phosphorylation of stat protein GO:0033141 3 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.055
negative regulation of interleukin 5 secretion GO:2000663 1 0.055
female gamete generation GO:0007292 2 0.042
negative regulation of protein metabolic process GO:0051248 391 0.042
immune response GO:0006955 307 0.040
negative regulation of interleukin 13 secretion GO:2000666 1 0.040
cation transmembrane transport GO:0098655 238 0.039
defense response GO:0006952 315 0.039
positive regulation of cell proliferation GO:0008284 301 0.039
response to biotic stimulus GO:0009607 276 0.038
response to other organism GO:0051707 261 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
oogenesis GO:0048477 2 0.035
regulation of cell cycle GO:0051726 393 0.034
transmembrane transport GO:0055085 399 0.033
inorganic ion transmembrane transport GO:0098660 231 0.033
response to cytokine GO:0034097 232 0.032
regulation of locomotion GO:0040012 329 0.032
regulation of transferase activity GO:0051338 355 0.032
response to external biotic stimulus GO:0043207 261 0.032
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.031
regulation of peptidyl serine phosphorylation of stat protein GO:0033139 3 0.031
innate immune response GO:0045087 178 0.030
segmentation GO:0035282 4 0.029
mitotic cell cycle GO:0000278 326 0.029
response to abiotic stimulus GO:0009628 336 0.028
system process GO:0003008 349 0.028
ion transmembrane transport GO:0034220 338 0.028
cellular response to endogenous stimulus GO:0071495 336 0.027
multicellular organismal aging GO:0010259 3 0.027
oxidation reduction process GO:0055114 396 0.027
regulation of meiotic cell cycle GO:0051445 4 0.027
lipid metabolic process GO:0006629 381 0.027
regulation of establishment of protein localization GO:0070201 242 0.027
single organism cellular localization GO:1902580 332 0.026
sensory perception of smell GO:0007608 2 0.026
reactive nitrogen species metabolic process GO:2001057 3 0.026
regulation of cell cycle process GO:0010564 266 0.026
determination of adult lifespan GO:0008340 2 0.025
organonitrogen compound biosynthetic process GO:1901566 200 0.025
regeneration GO:0031099 4 0.025
negative regulation of programmed cell death GO:0043069 321 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
rna processing GO:0006396 255 0.024
response to oxygen containing compound GO:1901700 369 0.024
cytokine production GO:0001816 247 0.024
anion transport GO:0006820 161 0.024
regulation of cytokine production GO:0001817 232 0.024
cellular macromolecule catabolic process GO:0044265 380 0.024
positive regulation of protein phosphorylation GO:0001934 313 0.024
response to organic cyclic compound GO:0014070 204 0.024
intracellular protein transport GO:0006886 270 0.024
cytoplasmic transport GO:0016482 379 0.024
organelle fission GO:0048285 149 0.024
carbohydrate metabolic process GO:0005975 207 0.024
positive regulation of phosphorylation GO:0042327 394 0.023
cellular lipid metabolic process GO:0044255 303 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
chromatin organization GO:0006325 351 0.023
small molecule biosynthetic process GO:0044283 157 0.023
monocarboxylic acid metabolic process GO:0032787 185 0.023
reactive oxygen species biosynthetic process GO:1903409 4 0.023
regulation of response to external stimulus GO:0032101 222 0.023
cellular response to cytokine stimulus GO:0071345 181 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.022
single organism carbohydrate metabolic process GO:0044723 193 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
regulation of proteolysis GO:0030162 293 0.022
biological adhesion GO:0022610 331 0.022
response to bacterium GO:0009617 144 0.021
response to lipid GO:0033993 206 0.021
inorganic cation transmembrane transport GO:0098662 194 0.021
apoptotic signaling pathway GO:0097190 268 0.021
cell division GO:0051301 168 0.021
positive regulation of apoptotic process GO:0043065 246 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
cation transport GO:0006812 331 0.020
mitotic cell cycle process GO:1903047 286 0.020
regulation of protein transport GO:0051223 213 0.020
protein maturation GO:0051604 233 0.020
oocyte differentiation GO:0009994 2 0.020
protein modification by small protein conjugation GO:0032446 342 0.020
organophosphate catabolic process GO:0046434 430 0.020
negative regulation of cellular component organization GO:0051129 235 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
negative regulation of t helper 2 cell cytokine production GO:2000552 2 0.019
t helper 2 cell cytokine production GO:0035745 3 0.019
meiosis i GO:0007127 4 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
protein catabolic process GO:0030163 325 0.019
cell cycle phase transition GO:0044770 173 0.019
vesicle mediated transport GO:0016192 371 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
chemical homeostasis GO:0048878 306 0.018
negative regulation of cell death GO:0060548 345 0.018
regulation of cell motility GO:2000145 299 0.018
positive regulation of developmental process GO:0051094 314 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
oocyte development GO:0048599 1 0.018
spermatid differentiation GO:0048515 4 0.018
positive regulation of immune system process GO:0002684 283 0.018
regulation of kinase activity GO:0043549 314 0.018
chromatin modification GO:0016568 298 0.018
secretion by cell GO:0032940 226 0.018
regulation of immune response GO:0050776 201 0.018
monovalent inorganic cation transport GO:0015672 128 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
regulation of protein localization GO:0032880 296 0.018
cell growth GO:0016049 160 0.018
blastoderm segmentation GO:0007350 2 0.018
regulation of protein maturation GO:1903317 150 0.018
negative regulation of cell cycle GO:0045786 193 0.017
ras protein signal transduction GO:0007265 73 0.017
membrane organization GO:0061024 292 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
protein processing GO:0016485 226 0.017
regulation of acrosome reaction GO:0060046 4 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
negative regulation of transport GO:0051051 176 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
positive regulation of cell cycle GO:0045787 140 0.017
cellular response to lipid GO:0071396 127 0.017
nuclear division GO:0000280 128 0.017
regulation of cellular component movement GO:0051270 334 0.017
locomotory behavior GO:0007626 1 0.017
single organism membrane organization GO:0044802 268 0.017
positive regulation of cell death GO:0010942 263 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
positive regulation of catabolic process GO:0009896 310 0.017
cell adhesion GO:0007155 325 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
organ formation GO:0048645 3 0.016
startle response GO:0001964 3 0.016
regulation of cell adhesion GO:0030155 166 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
g protein coupled receptor signaling pathway GO:0007186 207 0.016
cell activation GO:0001775 213 0.016
negative regulation of interleukin 5 production GO:0032714 3 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
nerve development GO:0021675 4 0.016
spermatid development GO:0007286 4 0.016
regulation of secretion by cell GO:1903530 177 0.016
regulation of t helper 2 cell cytokine production GO:2000551 2 0.016
cellular protein catabolic process GO:0044257 261 0.016
cellular response to histamine GO:0071420 3 0.016
negative regulation of protein modification process GO:0031400 200 0.016
inorganic anion transmembrane transport GO:0098661 47 0.016
actin filament based process GO:0030029 224 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
protein localization to organelle GO:0033365 280 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
peptidyl tyrosine modification GO:0018212 170 0.016
interleukin 13 secretion GO:0072611 2 0.016
neuromuscular junction development GO:0007528 3 0.016
positive regulation of acrosome reaction GO:2000344 4 0.016
organic hydroxy compound metabolic process GO:1901615 147 0.016
organic hydroxy compound biosynthetic process GO:1901617 71 0.016
response to fungus GO:0009620 4 0.016
regulation of protein kinase activity GO:0045859 289 0.016
cellular response to organic cyclic compound GO:0071407 127 0.016
anterior posterior axis specification GO:0009948 2 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.015
sensory perception GO:0007600 103 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
epidermis morphogenesis GO:0048730 3 0.015
fatty acid metabolic process GO:0006631 115 0.015
regulation of multi organism process GO:0043900 157 0.015
lipid biosynthetic process GO:0008610 177 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
positive regulation of cytokine production GO:0001819 167 0.015
tissue regeneration GO:0042246 3 0.015
nucleotide catabolic process GO:0009166 408 0.015
positive regulation of cellular component movement GO:0051272 181 0.015
neurological system process GO:0050877 163 0.015
protein ubiquitination GO:0016567 314 0.015
adult locomotory behavior GO:0008344 1 0.015
regulation of protein secretion GO:0050708 86 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
nuclear transport GO:0051169 179 0.015
interspecies interaction between organisms GO:0044419 156 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
regulation of cell division GO:0051302 116 0.015
negative regulation of type 2 immune response GO:0002829 3 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
small gtpase mediated signal transduction GO:0007264 78 0.014
regulation of protein processing GO:0070613 150 0.014
viral life cycle GO:0019058 132 0.014
immune effector process GO:0002252 159 0.014
purine containing compound catabolic process GO:0072523 411 0.014
immune system development GO:0002520 195 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
cell development GO:0048468 328 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
regulation of secretion GO:0051046 194 0.014
positive regulation of cell migration GO:0030335 172 0.014
nitrogen compound transport GO:0071705 191 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
protein acetylation GO:0006473 116 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
maintenance of location GO:0051235 112 0.014
viral process GO:0016032 146 0.014
regulation of cell growth GO:0001558 135 0.014
response to nitrogen compound GO:1901698 184 0.014
negative regulation of protein processing GO:0010955 142 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.014
positive regulation of cell motility GO:2000147 177 0.014
limbic system development GO:0021761 3 0.014
negative regulation of protein maturation GO:1903318 142 0.014
regulation of growth GO:0040008 165 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
negative regulation of growth GO:0045926 97 0.014
steroid metabolic process GO:0008202 94 0.014
protein acylation GO:0043543 138 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
hemopoiesis GO:0030097 180 0.014
natural killer cell activation involved in immune response GO:0002323 2 0.014
cell fate determination GO:0001709 3 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
mitochondrion organization GO:0007005 156 0.013
regulation of peptidase activity GO:0052547 180 0.013
response to wounding GO:0009611 168 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
secretion GO:0046903 254 0.013
response to hormone GO:0009725 175 0.013
metal ion transport GO:0030001 272 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
peptidyl serine modification GO:0018209 106 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
positive regulation of transport GO:0051050 336 0.013
positive regulation of transferase activity GO:0051347 227 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
covalent chromatin modification GO:0016569 254 0.013
microtubule based process GO:0007017 210 0.013
regulation of meiosis GO:0040020 3 0.013
negative regulation of developmental process GO:0051093 247 0.013
cellular component morphogenesis GO:0032989 314 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
morphogenesis of embryonic epithelium GO:0016331 4 0.013
regulation of intracellular transport GO:0032386 195 0.013
thymus development GO:0048538 3 0.013
regulation of cell differentiation GO:0045595 393 0.013
multi organism cellular process GO:0044764 156 0.013
protein secretion GO:0009306 98 0.013
regulation of viral process GO:0050792 103 0.013
interleukin 5 secretion GO:0072603 2 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
mapk cascade GO:0000165 288 0.013
meiotic chromosome segregation GO:0045132 4 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
protein targeting GO:0006605 187 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
positive regulation of cell differentiation GO:0045597 211 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
alcohol metabolic process GO:0006066 114 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
leukocyte activation GO:0045321 164 0.012
positive regulation of organelle organization GO:0010638 195 0.012
positive regulation of locomotion GO:0040017 186 0.012
regulation of protein catabolic process GO:0042176 155 0.012
single organism reproductive process GO:0044702 98 0.012
divalent inorganic cation transport GO:0072511 158 0.012
negative regulation of locomotion GO:0040013 118 0.012
response to steroid hormone GO:0048545 80 0.012
translation GO:0006412 132 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
cell morphogenesis GO:0000902 296 0.012
cellular response to hydroxyisoflavone GO:0071413 1 0.012
negative regulation of proteolysis GO:0045861 132 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
myoblast fusion GO:0007520 1 0.012
cellular carbohydrate metabolic process GO:0044262 84 0.012
nitrogen cycle metabolic process GO:0071941 3 0.012
small molecule catabolic process GO:0044282 92 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
defense response to other organism GO:0098542 129 0.012
reproductive process GO:0022414 106 0.012
nervous system development GO:0007399 293 0.012
dephosphorylation GO:0016311 209 0.012
positive regulation of protein transport GO:0051222 135 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
ion homeostasis GO:0050801 230 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
positive regulation of kinase activity GO:0033674 204 0.012
hair follicle morphogenesis GO:0031069 2 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
actin cytoskeleton organization GO:0030036 207 0.012
memory GO:0007613 3 0.012
negative regulation of transmission of nerve impulse GO:0051970 1 0.012
methylation GO:0032259 106 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
microtubule cytoskeleton organization GO:0000226 176 0.011
negative regulation of synaptic transmission GO:0050805 2 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
rna splicing GO:0008380 131 0.011
peptidyl serine phosphorylation GO:0018105 101 0.011
epithelial cell migration GO:0010631 119 0.011
regulation of protein complex assembly GO:0043254 147 0.011
regulation of cell migration GO:0030334 289 0.011
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
regulation of cellular response to stress GO:0080135 244 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
cation homeostasis GO:0055080 189 0.011
epithelium development GO:0060429 227 0.011
cellular chemical homeostasis GO:0055082 180 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
negative regulation of cell growth GO:0030308 83 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
tripartite regional subdivision GO:0007351 2 0.011
regulation of binding GO:0051098 111 0.011
negative regulation of t cell cytokine production GO:0002725 4 0.011
hindbrain development GO:0030902 3 0.011
mrna metabolic process GO:0016071 175 0.011
somatic muscle development GO:0007525 1 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
tissue migration GO:0090130 119 0.011
regulation of membrane potential GO:0042391 95 0.011
histone modification GO:0016570 251 0.011
response to virus GO:0009615 126 0.011
somitogenesis GO:0001756 2 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
negative regulation of cytokine production GO:0001818 82 0.011
compound eye development GO:0048749 1 0.011
cellular response to genistein GO:0071412 1 0.011
organelle assembly GO:0070925 176 0.011
ossification GO:0001503 121 0.011
positive regulation of hormone biosynthetic process GO:0046886 4 0.011
response to decreased oxygen levels GO:0036293 96 0.011
wnt signaling pathway GO:0016055 156 0.011
cyclic nucleotide metabolic process GO:0009187 82 0.011
growth GO:0040007 202 0.011
epithelial cell proliferation GO:0050673 128 0.011
rho protein signal transduction GO:0007266 26 0.011
regulation of interleukin 5 secretion GO:2000662 2 0.011
activation of immune response GO:0002253 114 0.010
circadian behavior GO:0048512 2 0.010
negative regulation of transferase activity GO:0051348 124 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.010
negative regulation of protein transport GO:0051224 75 0.010
response to axon injury GO:0048678 1 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010
rhythmic behavior GO:0007622 2 0.010
mitotic nuclear division GO:0007067 119 0.010
regulation of transmission of nerve impulse GO:0051969 2 0.010
epithelium migration GO:0090132 119 0.010
nucleoside triphosphate catabolic process GO:0009143 394 0.010
chromosome segregation GO:0007059 114 0.010
endomembrane system organization GO:0010256 196 0.010
wound healing GO:0042060 115 0.010
oocyte maturation GO:0001556 1 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
ribonucleoside monophosphate metabolic process GO:0009161 187 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
negative regulation of cell migration GO:0030336 102 0.010
response to activity GO:0014823 0 0.010
ubiquitin dependent protein catabolic process GO:0006511 206 0.010
hormone metabolic process GO:0042445 61 0.010
regulation of interleukin 13 secretion GO:2000665 2 0.010
response to oxygen levels GO:0070482 100 0.010
dna repair GO:0006281 198 0.010
negative regulation of cellular component movement GO:0051271 106 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010

SPO11 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.030
inherited metabolic disorder DOID:655 242 0.030
sensory system disease DOID:0050155 203 0.027
nervous system disease DOID:863 431 0.027
eye and adnexa disease DOID:1492 150 0.022
eye disease DOID:5614 149 0.021
immune system disease DOID:2914 155 0.018
retinal disease DOID:5679 118 0.018
musculoskeletal system disease DOID:17 223 0.014
blindness DOID:1432 8 0.014
color blindness DOID:13399 8 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
organ system cancer DOID:0050686 164 0.013
hematopoietic system disease DOID:74 100 0.012
connective tissue disease DOID:65 109 0.011
central nervous system disease DOID:331 186 0.011
achromatopsia DOID:13911 7 0.010