Homo sapiens

163 known processes

ACSL3

acyl-CoA synthetase long-chain family member 3

(Aliases: FACL3,PRO2194,ACS3)

ACSL3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 303 0.318
associative learning GO:0008306 1 0.254
lipid metabolic process GO:0006629 381 0.231
cellular amino acid metabolic process GO:0006520 116 0.170
post embryonic development GO:0009791 2 0.150
regulation of transferase activity GO:0051338 355 0.140
membrane organization GO:0061024 292 0.107
single organism membrane organization GO:0044802 268 0.097
amine metabolic process GO:0009308 44 0.096
multicellular organismal aging GO:0010259 3 0.088
regulation of kinase activity GO:0043549 314 0.088
secretion GO:0046903 254 0.078
small molecule biosynthetic process GO:0044283 157 0.077
cytoplasmic transport GO:0016482 379 0.077
system process GO:0003008 349 0.075
regulation of protein kinase activity GO:0045859 289 0.075
determination of adult lifespan GO:0008340 2 0.073
oogenesis GO:0048477 2 0.070
single organism cellular localization GO:1902580 332 0.068
glycerolipid metabolic process GO:0046486 107 0.068
regulation of mapk cascade GO:0043408 262 0.066
negative regulation of protein metabolic process GO:0051248 391 0.065
establishment of protein localization to organelle GO:0072594 172 0.065
lipid biosynthetic process GO:0008610 177 0.065
protein localization to organelle GO:0033365 280 0.064
neurological system process GO:0050877 163 0.063
chemical homeostasis GO:0048878 306 0.062
negative regulation of catalytic activity GO:0043086 335 0.062
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.061
organophosphate biosynthetic process GO:0090407 163 0.061
regulation of map kinase activity GO:0043405 108 0.059
regulation of vesicle mediated transport GO:0060627 130 0.059
female gamete generation GO:0007292 2 0.058
nucleoside phosphate catabolic process GO:1901292 412 0.057
regulation of cellular amine metabolic process GO:0033238 11 0.056
purine containing compound catabolic process GO:0072523 411 0.055
purine ribonucleoside metabolic process GO:0046128 437 0.054
nucleoside triphosphate catabolic process GO:0009143 394 0.053
negative regulation of phosphate metabolic process GO:0045936 267 0.053
purine ribonucleotide catabolic process GO:0009154 404 0.053
nucleoside catabolic process GO:0009164 408 0.052
regulation of cellular component biogenesis GO:0044087 281 0.052
ion homeostasis GO:0050801 230 0.050
negative regulation of protein phosphorylation GO:0001933 140 0.050
nucleoside triphosphate metabolic process GO:0009141 422 0.049
visual behavior GO:0007632 2 0.047
purine nucleotide catabolic process GO:0006195 405 0.047
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
purine nucleoside triphosphate metabolic process GO:0009144 412 0.045
protein targeting GO:0006605 187 0.045
signal transduction by phosphorylation GO:0023014 297 0.045
cofactor metabolic process GO:0051186 87 0.044
Yeast
ion transmembrane transport GO:0034220 338 0.044
negative regulation of kinase activity GO:0033673 106 0.043
cation transmembrane transport GO:0098655 238 0.042
cellular protein catabolic process GO:0044257 261 0.042
cellular ketone metabolic process GO:0042180 80 0.041
ribonucleoside catabolic process GO:0042454 406 0.041
vesicle mediated transport GO:0016192 371 0.040
visual learning GO:0008542 1 0.040
negative regulation of cellular protein metabolic process GO:0032269 353 0.039
protein catabolic process GO:0030163 325 0.039
metal ion transport GO:0030001 272 0.039
negative regulation of intracellular signal transduction GO:1902532 183 0.039
regulation of cytoplasmic transport GO:1903649 149 0.038
mapk cascade GO:0000165 288 0.038
defense response GO:0006952 315 0.038
negative regulation of cell death GO:0060548 345 0.038
ribonucleoside triphosphate metabolic process GO:0009199 412 0.038
inorganic cation transmembrane transport GO:0098662 194 0.038
glycosyl compound catabolic process GO:1901658 413 0.037
neuromuscular junction development GO:0007528 3 0.037
organic hydroxy compound metabolic process GO:1901615 147 0.037
intracellular protein transport GO:0006886 270 0.037
negative regulation of phosphorus metabolic process GO:0010563 267 0.037
inorganic ion transmembrane transport GO:0098660 231 0.036
response to cytokine GO:0034097 232 0.036
organonitrogen compound biosynthetic process GO:1901566 200 0.036
organophosphate catabolic process GO:0046434 430 0.036
regulation of membrane potential GO:0042391 95 0.035
positive regulation of cellular amine metabolic process GO:0033240 7 0.035
response to oxygen containing compound GO:1901700 369 0.034
purine nucleoside catabolic process GO:0006152 398 0.033
response to light stimulus GO:0009416 87 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.033
cation transport GO:0006812 331 0.033
sulfur compound metabolic process GO:0006790 101 0.032
Yeast
negative regulation of phosphorylation GO:0042326 174 0.032
positive regulation of catabolic process GO:0009896 310 0.031
negative regulation of protein modification process GO:0031400 200 0.031
locomotory behavior GO:0007626 1 0.031
nucleotide catabolic process GO:0009166 408 0.030
maintenance of location GO:0051235 112 0.030
regulation of protein transport GO:0051223 213 0.030
regulation of ion transport GO:0043269 189 0.030
Human
ribonucleotide catabolic process GO:0009261 405 0.030
peripheral nervous system development GO:0007422 2 0.029
anion transport GO:0006820 161 0.029
cellular amine metabolic process GO:0044106 41 0.029
regulation of cellular ketone metabolic process GO:0010565 50 0.029
embryo development GO:0009790 123 0.029
Worm
memory GO:0007613 3 0.028
regulation of cell cycle GO:0051726 393 0.028
cellular modified amino acid metabolic process GO:0006575 64 0.028
positive regulation of transport GO:0051050 336 0.028
positive regulation of nucleoside metabolic process GO:0045979 186 0.028
proteasomal protein catabolic process GO:0010498 176 0.028
carboxylic acid transport GO:0046942 63 0.027
monocarboxylic acid metabolic process GO:0032787 185 0.027
response to radiation GO:0009314 151 0.027
terpenoid biosynthetic process GO:0016114 2 0.027
ras protein signal transduction GO:0007265 73 0.027
regulation of defense response GO:0031347 154 0.027
positive regulation of hydrolase activity GO:0051345 331 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.027
cellular chemical homeostasis GO:0055082 180 0.027
actin filament based process GO:0030029 224 0.027
dephosphorylation GO:0016311 209 0.027
nitrogen compound transport GO:0071705 191 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.026
sphingolipid metabolic process GO:0006665 38 0.026
apoptotic mitochondrial changes GO:0008637 57 0.025
metal ion homeostasis GO:0055065 169 0.025
modification dependent protein catabolic process GO:0019941 209 0.025
microtubule based process GO:0007017 210 0.025
gtp catabolic process GO:0006184 237 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.025
nervous system development GO:0007399 293 0.025
Rat
cellular macromolecule catabolic process GO:0044265 380 0.025
regulation of establishment of protein localization GO:0070201 242 0.025
negative regulation of protein kinase activity GO:0006469 98 0.024
epithelium development GO:0060429 227 0.024
cell morphogenesis GO:0000902 296 0.024
endomembrane system organization GO:0010256 196 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
response to biotic stimulus GO:0009607 276 0.024
cellular homeostasis GO:0019725 196 0.024
spermatid differentiation GO:0048515 4 0.024
response to lipid GO:0033993 206 0.024
positive regulation of protein phosphorylation GO:0001934 313 0.023
long term memory GO:0007616 2 0.023
terpenoid metabolic process GO:0006721 27 0.023
long chain fatty acid metabolic process GO:0001676 30 0.023
ubiquitin dependent protein catabolic process GO:0006511 206 0.023
monocarboxylic acid biosynthetic process GO:0072330 67 0.023
Rat
nuclear transport GO:0051169 179 0.022
regulation of proteolysis GO:0030162 293 0.022
protein deubiquitination GO:0016579 79 0.022
establishment of nucleus localization GO:0040023 1 0.022
apoptotic signaling pathway GO:0097190 268 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
growth GO:0040007 202 0.022
Human
small gtpase mediated signal transduction GO:0007264 78 0.022
response to external biotic stimulus GO:0043207 261 0.022
negative regulation of map kinase activity GO:0043407 27 0.021
regulation of homeostatic process GO:0032844 121 0.021
cation homeostasis GO:0055080 189 0.021
guanosine containing compound catabolic process GO:1901069 239 0.021
nucleus localization GO:0051647 1 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
segmentation GO:0035282 4 0.021
compound eye development GO:0048749 1 0.021
single organism nuclear import GO:1902593 104 0.021
regulation of protein localization GO:0032880 296 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
organic hydroxy compound biosynthetic process GO:1901617 71 0.020
anatomical structure formation involved in morphogenesis GO:0048646 284 0.020
interspecies interaction between organisms GO:0044419 156 0.020
lipid storage GO:0019915 28 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.020
morphogenesis of embryonic epithelium GO:0016331 4 0.020
cellular component morphogenesis GO:0032989 314 0.020
plasma membrane organization GO:0007009 115 0.020
negative regulation of transferase activity GO:0051348 124 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
monovalent inorganic cation transport GO:0015672 128 0.020
steroid metabolic process GO:0008202 94 0.020
regulation of locomotion GO:0040012 329 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
secretion by cell GO:0032940 226 0.020
alcohol metabolic process GO:0006066 114 0.020
transmembrane transport GO:0055085 399 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
ribonucleoside monophosphate catabolic process GO:0009158 158 0.019
cellular divalent inorganic cation homeostasis GO:0072503 128 0.019
positive regulation of kinase activity GO:0033674 204 0.019
protein localization to membrane GO:0072657 160 0.019
mitotic cell cycle process GO:1903047 286 0.019
guanosine containing compound metabolic process GO:1901068 244 0.019
inner ear morphogenesis GO:0042472 4 0.019
gtp metabolic process GO:0046039 239 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.019
nucleoside monophosphate catabolic process GO:0009125 159 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
regulation of metal ion transport GO:0010959 120 0.018
nuclear migration GO:0007097 1 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
tripartite regional subdivision GO:0007351 2 0.018
modification dependent macromolecule catabolic process GO:0043632 212 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
reactive nitrogen species metabolic process GO:2001057 3 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.018
nuclear import GO:0051170 106 0.018
divalent inorganic cation homeostasis GO:0072507 136 0.018
hindbrain development GO:0030902 3 0.018
mitochondrion organization GO:0007005 156 0.018
immune response GO:0006955 307 0.018
innate immune response GO:0045087 178 0.017
cell projection organization GO:0030030 252 0.017
cell division GO:0051301 168 0.017
neural tube formation GO:0001841 3 0.017
regulation of cellular response to stress GO:0080135 244 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
divalent inorganic cation transport GO:0072511 158 0.017
cell development GO:0048468 328 0.017
lipid localization GO:0010876 106 0.017
protein processing GO:0016485 226 0.017
endosomal transport GO:0016197 129 0.017
limbic system development GO:0021761 3 0.017
negative regulation of immune system process GO:0002683 136 0.017
potassium ion transport GO:0006813 62 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
cellular response to endogenous stimulus GO:0071495 336 0.017
mitotic cell cycle GO:0000278 326 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
cellular cation homeostasis GO:0030003 163 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
regulation of multi organism process GO:0043900 157 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
reproductive process GO:0022414 106 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
oxidation reduction process GO:0055114 396 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
response to inorganic substance GO:0010035 127 0.015
cell part morphogenesis GO:0032990 137 0.015
protein tetramerization GO:0051262 47 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
cilium morphogenesis GO:0060271 75 0.015
oocyte development GO:0048599 1 0.015
establishment of organelle localization GO:0051656 59 0.015
chemotaxis GO:0006935 157 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.015
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
membrane lipid metabolic process GO:0006643 53 0.015
organ morphogenesis GO:0009887 147 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
protein modification by small protein removal GO:0070646 92 0.015
protein oligomerization GO:0051259 173 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
regulation of transporter activity GO:0032409 82 0.015
cognition GO:0050890 43 0.014
head development GO:0060322 108 0.014
Rat
behavior GO:0007610 112 0.014
sensory perception GO:0007600 103 0.014
protein maturation GO:0051604 233 0.014
positive regulation of cell death GO:0010942 263 0.014
calcium ion transmembrane transport GO:0070588 76 0.014
vesicle targeting rough er to cis golgi GO:0048207 2 0.014
regulation of gtpase activity GO:0043087 180 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
regulation of response to external stimulus GO:0032101 222 0.014
oocyte differentiation GO:0009994 2 0.014
blastoderm segmentation GO:0007350 2 0.014
cell adhesion GO:0007155 325 0.014
viral process GO:0016032 146 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
regulation of stress activated mapk cascade GO:0032872 84 0.014
spermatid development GO:0007286 4 0.014
cell growth GO:0016049 160 0.014
Human
glycerophospholipid biosynthetic process GO:0046474 40 0.013
cellular ion homeostasis GO:0006873 168 0.013
cerebellum development GO:0021549 2 0.013
organic acid transport GO:0015849 65 0.013
regulation of intracellular transport GO:0032386 195 0.013
regulation of cell differentiation GO:0045595 393 0.013
response to abiotic stimulus GO:0009628 336 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
response to endoplasmic reticulum stress GO:0034976 49 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
cellular response to organic cyclic compound GO:0071407 127 0.013
response to oxidative stress GO:0006979 121 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
biological adhesion GO:0022610 331 0.013
calcium ion homeostasis GO:0055074 122 0.013
response to nitrogen compound GO:1901698 184 0.013
calcium ion transport GO:0006816 147 0.013
cellular protein complex assembly GO:0043623 188 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.013
phospholipid metabolic process GO:0006644 99 0.013
multi organism cellular process GO:0044764 156 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
positive regulation of secretion GO:0051047 116 0.012
carboxylic acid catabolic process GO:0046395 71 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of ion transmembrane transport GO:0034765 132 0.012
response to organic cyclic compound GO:0014070 204 0.012
Rat
regulation of nucleoside metabolic process GO:0009118 209 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
adult locomotory behavior GO:0008344 1 0.012
cellular potassium ion transport GO:0071804 60 0.012
regeneration GO:0031099 4 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
positive regulation of transferase activity GO:0051347 227 0.012
alcohol biosynthetic process GO:0046165 52 0.012
response to hormone GO:0009725 175 0.012
viral life cycle GO:0019058 132 0.012
hippocampus development GO:0021766 1 0.012
membrane budding GO:0006900 28 0.012
embryonic morphogenesis GO:0048598 85 0.012
neurofilament cytoskeleton organization GO:0060052 2 0.012
response to organonitrogen compound GO:0010243 156 0.012
stress activated mapk cascade GO:0051403 93 0.012
multicellular organismal signaling GO:0035637 34 0.012
cell fate determination GO:0001709 3 0.012
cellular amide metabolic process GO:0043603 69 0.012
positive regulation of organelle organization GO:0010638 195 0.012
glycerophospholipid metabolic process GO:0006650 84 0.012
endodermal cell fate commitment GO:0001711 4 0.012
regulation of gtp catabolic process GO:0033124 180 0.011
positive regulation of cell cycle GO:0045787 140 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.011
protein import GO:0017038 130 0.011
positive regulation of ion transport GO:0043270 87 0.011
regulation of immune effector process GO:0002697 91 0.011
neural tube closure GO:0001843 3 0.011
cellular calcium ion homeostasis GO:0006874 117 0.011
tissue regeneration GO:0042246 3 0.011
immune effector process GO:0002252 159 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
divalent metal ion transport GO:0070838 152 0.011
regulation of nucleocytoplasmic transport GO:0046822 98 0.011
wnt signaling pathway GO:0016055 156 0.011
regulation of cellular component movement GO:0051270 334 0.011
eye photoreceptor cell differentiation GO:0001754 2 0.011
atp metabolic process GO:0046034 176 0.011
regulation of icosanoid secretion GO:0032303 4 0.011
Human
regulation of immune response GO:0050776 201 0.011
regulation of cell growth GO:0001558 135 0.011
Human
positive regulation of protein kinase activity GO:0045860 190 0.011
neurogenesis GO:0022008 169 0.011
neuronal action potential GO:0019228 9 0.011
peptidyl threonine phosphorylation GO:0018107 41 0.011
positive regulation of immune system process GO:0002684 283 0.011
protein import into nucleus GO:0006606 104 0.011
action potential GO:0001508 34 0.011
negative regulation of developmental process GO:0051093 247 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
aging GO:0007568 66 0.011
response to phenylpropanoid GO:0080184 1 0.011
nerve development GO:0021675 4 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
regulation of translation GO:0006417 89 0.010
anterior posterior axis specification GO:0009948 2 0.010
atp catabolic process GO:0006200 157 0.010
negative regulation of icosanoid secretion GO:0032304 2 0.010
Human
regulation of transmembrane transporter activity GO:0022898 74 0.010
metencephalon development GO:0022037 2 0.010
anion transmembrane transport GO:0098656 76 0.010
regulation of growth GO:0040008 165 0.010
Human
positive regulation of wnt signaling pathway GO:0030177 54 0.010
sodium ion transport GO:0006814 61 0.010
regulation of cell cycle process GO:0010564 266 0.010
regulation of cell motility GO:2000145 299 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
positive regulation of gtpase activity GO:0043547 166 0.010
regulation of cell migration GO:0030334 289 0.010
actin cytoskeleton organization GO:0030036 207 0.010
defense response to other organism GO:0098542 129 0.010
response to virus GO:0009615 126 0.010
rho protein signal transduction GO:0007266 26 0.010
positive regulation of cell migration GO:0030335 172 0.010
endocytosis GO:0006897 159 0.010
regulation of protein catabolic process GO:0042176 155 0.010
alpha amino acid metabolic process GO:1901605 72 0.010
generation of neurons GO:0048699 152 0.010

ACSL3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.036
central nervous system disease DOID:331 186 0.033
nervous system disease DOID:863 431 0.033
musculoskeletal system disease DOID:17 223 0.020
carbohydrate metabolic disorder DOID:2978 55 0.017
inherited metabolic disorder DOID:655 242 0.017
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
disease of mental health DOID:150 70 0.015
Human
immune system disease DOID:2914 155 0.013
glycogen storage disease DOID:2747 10 0.012
glycogen metabolism disorder DOID:0050728 10 0.012
connective tissue disease DOID:65 109 0.011
organ system cancer DOID:0050686 164 0.010