Homo sapiens

101 known processes

TRIM38

tripartite motif containing 38

(Aliases: RNF15,RORET,MGC8946)

TRIM38 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune effector process GO:0002252 159 0.425
Human Mouse
cellular response to muramyl dipeptide GO:0071225 3 0.314
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.272
immune response GO:0006955 307 0.234
Human
adaptive immune response GO:0002250 49 0.217
Human
positive regulation of immune system process GO:0002684 283 0.214
Human
positive regulation of cytokine production GO:0001819 167 0.200
Human
immune response activating signal transduction GO:0002757 90 0.198
Human
activation of innate immune response GO:0002218 55 0.182
Human
regulation of cytokine production GO:0001817 232 0.173
Human Mouse
regulation of innate immune response GO:0045088 97 0.168
Human
positive regulation of defense response GO:0031349 87 0.162
Human
pattern recognition receptor signaling pathway GO:0002221 48 0.148
Human
activation of immune response GO:0002253 114 0.131
Human
viral life cycle GO:0019058 132 0.126
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.124
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.121
Human
positive regulation of innate immune response GO:0045089 79 0.117
Human
innate immune response GO:0045087 178 0.103
Human
regulation of establishment of protein localization GO:0070201 242 0.102
Human
positive regulation of immune response GO:0050778 159 0.098
Human
cytokine production GO:0001816 247 0.096
Human Mouse
regulation of lymphocyte activation GO:0051249 103 0.092
defense response to virus GO:0051607 71 0.090
Human Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.089
Human
positive regulation of developmental process GO:0051094 314 0.087
innate immune response activating signal transduction GO:0002758 48 0.086
Human
regulation of protein localization GO:0032880 296 0.084
Human
cellular response to dna damage stimulus GO:0006974 379 0.079
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.078
regulation of multi organism process GO:0043900 157 0.078
immune response regulating signaling pathway GO:0002764 97 0.078
Human
toll like receptor 2 signaling pathway GO:0034134 4 0.073
fas signaling pathway GO:0036337 3 0.072
peptidyl serine autophosphorylation GO:0036289 2 0.072
regulation of mapk cascade GO:0043408 262 0.071
Human
regulation of fas signaling pathway GO:1902044 2 0.069
protein modification by small protein conjugation GO:0032446 342 0.068
Human Mouse
intracellular receptor signaling pathway GO:0030522 104 0.061
Human
lymphocyte mediated immunity GO:0002449 48 0.061
response to other organism GO:0051707 261 0.057
Human Mouse
response to external biotic stimulus GO:0043207 261 0.056
Human Mouse
cellular response to nitrogen compound GO:1901699 144 0.056
response to oxygen containing compound GO:1901700 369 0.055
Human
i kappab kinase nf kappab signaling GO:0007249 166 0.055
defense response GO:0006952 315 0.054
Human Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.054
regulation of mitotic cell cycle GO:0007346 189 0.053
multi organism cellular process GO:0044764 156 0.053
negative regulation of protein transport GO:0051224 75 0.052
Human
t cell mediated immunity GO:0002456 25 0.051
protein secretion GO:0009306 98 0.051
Human
regulation of protein secretion GO:0050708 86 0.050
Human
positive regulation of leukocyte differentiation GO:1902107 37 0.050
regulation of adaptive immune response GO:0002819 33 0.049
Human
regulation of cell differentiation GO:0045595 393 0.049
positive regulation of phosphorylation GO:0042327 394 0.049
Human
reactive oxygen species metabolic process GO:0072593 75 0.048
positive regulation of cell differentiation GO:0045597 211 0.048
negative regulation of multicellular organismal process GO:0051241 317 0.045
Human
ion transmembrane transport GO:0034220 338 0.045
Human
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.045
cell fate determination GO:0001709 3 0.044
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.044
Human
cytoplasmic transport GO:0016482 379 0.044
protein ubiquitination GO:0016567 314 0.044
Human Mouse
interspecies interaction between organisms GO:0044419 156 0.043
determination of adult lifespan GO:0008340 2 0.043
cellular response to endogenous stimulus GO:0071495 336 0.042
regeneration GO:0031099 4 0.042
cellular macromolecular complex assembly GO:0034622 324 0.042
Human
regulation of apoptotic signaling pathway GO:2001233 175 0.041
Human
regulation of ion transport GO:0043269 189 0.041
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.040
cellular macromolecule catabolic process GO:0044265 380 0.040
Human Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.040
regulation of kinase activity GO:0043549 314 0.040
Human
interferon gamma production GO:0032609 39 0.039
Human
actin filament based process GO:0030029 224 0.039
Human
regulation of t cell activation GO:0050863 77 0.039
regulation of protein transport GO:0051223 213 0.038
Human
mitotic cell cycle GO:0000278 326 0.038
leukocyte mediated immunity GO:0002443 59 0.038
positive regulation of cell death GO:0010942 263 0.038
Human
negative regulation of viral genome replication GO:0045071 35 0.037
angiogenesis GO:0001525 147 0.035
regulation of leukocyte differentiation GO:1902105 61 0.034
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.034
ubiquitin dependent protein catabolic process GO:0006511 206 0.034
Human Mouse
syncytium formation by plasma membrane fusion GO:0000768 2 0.034
positive regulation of transport GO:0051050 336 0.034
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.034
Human
response to virus GO:0009615 126 0.034
Human Mouse
regulation of immune response GO:0050776 201 0.034
Human
negative regulation of protein maturation GO:1903318 142 0.033
Human
regulation of cell cycle GO:0051726 393 0.033
Human
regulation of response to biotic stimulus GO:0002831 55 0.032
Human Mouse
secretion by cell GO:0032940 226 0.032
Human
nucleocytoplasmic transport GO:0006913 176 0.032
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.032
protein localization to organelle GO:0033365 280 0.032
negative regulation of transport GO:0051051 176 0.030
Human
leukocyte differentiation GO:0002521 98 0.030
multicellular organismal aging GO:0010259 3 0.030
protein catabolic process GO:0030163 325 0.030
Human Mouse
cation transport GO:0006812 331 0.030
Human
anatomical structure homeostasis GO:0060249 100 0.029
interleukin 1 beta production GO:0032611 22 0.028
mapk cascade GO:0000165 288 0.028
Human
circulatory system development GO:0072359 262 0.028
cellular ketone metabolic process GO:0042180 80 0.028
blood vessel morphogenesis GO:0048514 162 0.027
protein oligomerization GO:0051259 173 0.027
Human
negative regulation of viral process GO:0048525 66 0.027
Human
anion transport GO:0006820 161 0.027
positive regulation of necrotic cell death GO:0010940 4 0.027
t cell differentiation GO:0030217 29 0.027
positive regulation of interleukin 8 production GO:0032757 36 0.027
negative regulation of viral transcription GO:0032897 23 0.026
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.026
t cell activation GO:0042110 99 0.026
protein autoubiquitination GO:0051865 37 0.026
Human
cellular protein catabolic process GO:0044257 261 0.026
Human Mouse
posttranscriptional regulation of gene expression GO:0010608 213 0.026
Human
response to biotic stimulus GO:0009607 276 0.026
Human Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.026
g1 s transition of mitotic cell cycle GO:0000082 78 0.025
activated t cell proliferation GO:0050798 13 0.025
epithelium development GO:0060429 227 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.025
Human Mouse
regulation of proteolysis GO:0030162 293 0.025
Human
neural tube formation GO:0001841 3 0.025
regulation of secretion GO:0051046 194 0.025
Human
response to abiotic stimulus GO:0009628 336 0.025
defense response to other organism GO:0098542 129 0.025
Human Mouse
regulation of cell cycle process GO:0010564 266 0.025
cytokine secretion GO:0050663 64 0.024
Human
regulation of cell migration GO:0030334 289 0.024
regulation of cytokine secretion GO:0050707 57 0.024
Human
regulation of protein processing GO:0070613 150 0.024
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
myoblast fusion GO:0007520 1 0.024
regulation of transmembrane transporter activity GO:0022898 74 0.023
organophosphate biosynthetic process GO:0090407 163 0.023
compound eye development GO:0048749 1 0.023
regulation of t cell proliferation GO:0042129 42 0.023
intracellular protein transport GO:0006886 270 0.023
carbohydrate derivative transport GO:1901264 20 0.023
programmed necrotic cell death GO:0097300 18 0.023
neuromuscular junction development GO:0007528 3 0.023
regulation of anatomical structure morphogenesis GO:0022603 286 0.023
immune system development GO:0002520 195 0.023
secretion GO:0046903 254 0.023
Human
negative regulation of mitotic cell cycle GO:0045930 102 0.023
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.023
amine metabolic process GO:0009308 44 0.022
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.022
mitotic cell cycle phase transition GO:0044772 162 0.022
positive regulation of protein transport GO:0051222 135 0.022
regulation of reactive oxygen species metabolic process GO:2000377 41 0.022
positive regulation of cell activation GO:0050867 81 0.022
negative regulation of intracellular protein transport GO:0090317 42 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
Human
regulation of cellular component biogenesis GO:0044087 281 0.021
Human
positive regulation of interferon gamma production GO:0032729 26 0.021
regulation of transferase activity GO:0051338 355 0.021
Human
regulation of lymphocyte proliferation GO:0050670 64 0.021
cellular response to oxygen containing compound GO:1901701 276 0.021
Human
positive regulation of regulatory t cell differentiation GO:0045591 3 0.021
defense response to bacterium GO:0042742 63 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.021
hemopoiesis GO:0030097 180 0.021
nuclear transport GO:0051169 179 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
regulation of cell cycle g1 s phase transition GO:1902806 42 0.020
metal ion transport GO:0030001 272 0.020
Human
regulation of dna binding GO:0051101 37 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
Human
negative regulation of cellular component organization GO:0051129 235 0.020
regulation of transporter activity GO:0032409 82 0.020
apoptotic signaling pathway GO:0097190 268 0.020
Human
negative regulation of cell proliferation GO:0008285 228 0.020
regulation of mononuclear cell proliferation GO:0032944 65 0.020
positive regulation of protein kinase activity GO:0045860 190 0.020
tissue regeneration GO:0042246 3 0.020
positive regulation of apoptotic signaling pathway GO:2001235 70 0.020
Human
cell cycle g1 s phase transition GO:0044843 80 0.020
circadian behavior GO:0048512 2 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
extrinsic apoptotic signaling pathway GO:0097191 119 0.019
regulation of cytoplasmic transport GO:1903649 149 0.019
regulation of secretion by cell GO:1903530 177 0.019
Human
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
Human
positive regulation of secretion by cell GO:1903532 108 0.019
biological adhesion GO:0022610 331 0.019
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.019
cellular response to organonitrogen compound GO:0071417 124 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.019
Human Mouse
protein polyubiquitination GO:0000209 110 0.019
Human Mouse
regulation of intracellular transport GO:0032386 195 0.019
Human
dephosphorylation GO:0016311 209 0.018
sensory perception of taste GO:0050909 36 0.018
protein targeting GO:0006605 187 0.018
regulation of dephosphorylation GO:0035303 96 0.018
leukocyte apoptotic process GO:0071887 31 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
Human
negative regulation of cell cycle GO:0045786 193 0.018
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.018
regulation of interferon beta production GO:0032648 22 0.018
Mouse
spermatid development GO:0007286 4 0.018
positive regulation of kinase activity GO:0033674 204 0.018
activation of protein kinase activity GO:0032147 90 0.018
positive regulation of protein secretion GO:0050714 60 0.018
regulation of interleukin 8 production GO:0032677 49 0.018
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.018
regulation of angiogenesis GO:0045765 92 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
detection of chemical stimulus GO:0009593 55 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.017
response to nitrogen compound GO:1901698 184 0.017
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 12 0.017
Human
regulation of lymphocyte mediated immunity GO:0002706 33 0.017
negative regulation of multi organism process GO:0043901 92 0.017
Human Mouse
double strand break repair GO:0006302 101 0.017
regulation of endothelial cell migration GO:0010594 67 0.017
spermatid differentiation GO:0048515 4 0.017
lymphocyte proliferation GO:0046651 70 0.017
rna processing GO:0006396 255 0.017
interleukin 8 production GO:0032637 51 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
regulation of cellular response to stress GO:0080135 244 0.016
mitotic cell cycle process GO:1903047 286 0.016
regulation of ion transmembrane transport GO:0034765 132 0.016
Human
cellular component morphogenesis GO:0032989 314 0.016
viral release from host cell GO:0019076 21 0.016
Human
regulation of cell cycle phase transition GO:1901987 126 0.016
signal transduction in response to dna damage GO:0042770 57 0.016
response to cytokine GO:0034097 232 0.016
female gamete generation GO:0007292 2 0.016
regulation of protein ubiquitination GO:0031396 95 0.015
Human
negative regulation of cell cycle process GO:0010948 121 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
endomembrane system organization GO:0010256 196 0.015
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.015
ncrna processing GO:0034470 83 0.015
cellular response to peptide GO:1901653 59 0.015
nucleoside transport GO:0015858 8 0.015
glycoprotein metabolic process GO:0009100 110 0.015
cardiovascular system development GO:0072358 262 0.015
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.015
Human
negative regulation of viral release from host cell GO:1902187 12 0.015
Human
positive regulation of apoptotic process GO:0043065 246 0.015
Human
mrna metabolic process GO:0016071 175 0.015
negative regulation of epithelial cell migration GO:0010633 38 0.015
endosomal transport GO:0016197 129 0.015
Human
regulation of viral release from host cell GO:1902186 20 0.015
Human
leukocyte activation GO:0045321 164 0.015
response to acid chemical GO:0001101 66 0.015
positive regulation of necroptotic process GO:0060545 2 0.014
positive regulation of interleukin 10 secretion GO:2001181 2 0.014
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.014
detection of chemical stimulus involved in sensory perception of taste GO:0050912 31 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
cellular amino acid metabolic process GO:0006520 116 0.014
positive regulation of cell migration GO:0030335 172 0.014
cellular lipid metabolic process GO:0044255 303 0.014
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.014
regulation of transmembrane transport GO:0034762 139 0.014
Human
ripoptosome assembly GO:0097343 1 0.014
epithelial cell differentiation GO:0030855 141 0.014
negative regulation of t cell receptor signaling pathway GO:0050860 4 0.014
regulation of circadian sleep wake cycle GO:0042749 2 0.014
nitrogen compound transport GO:0071705 191 0.014
regulation of cellular component movement GO:0051270 334 0.014
protein autophosphorylation GO:0046777 123 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
regulation of intracellular protein transport GO:0033157 123 0.013
regulation of vasculature development GO:1901342 97 0.013
vesicle mediated transport GO:0016192 371 0.013
Human
midgut development GO:0007494 1 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
Human
cell morphogenesis GO:0000902 296 0.013
positive regulation of cytokine secretion GO:0050715 42 0.013
regulation of viral transcription GO:0046782 34 0.013
Human
cell division GO:0051301 168 0.013
regulation of phosphatase activity GO:0010921 81 0.013
regulation of nucleocytoplasmic transport GO:0046822 98 0.013
rhythmic behavior GO:0007622 2 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
detection of stimulus GO:0051606 85 0.013
t cell apoptotic process GO:0070231 12 0.013
response to bacterium GO:0009617 144 0.013
Human
response to muramyl dipeptide GO:0032495 4 0.013
sensory perception of chemical stimulus GO:0007606 38 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
positive regulation of lymphocyte activation GO:0051251 73 0.013
positive regulation of cytokine biosynthetic process GO:0042108 25 0.013
ribonucleoprotein complex subunit organization GO:0071826 81 0.013
rna splicing GO:0008380 131 0.013
regulation of leukocyte proliferation GO:0070663 67 0.013
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.013
Human
neuroblast proliferation GO:0007405 4 0.013
viral transcription GO:0019083 35 0.013
Human
ribonucleoprotein complex assembly GO:0022618 78 0.013
muscle structure development GO:0061061 98 0.013
positive regulation of catabolic process GO:0009896 310 0.012
protein import into nucleus GO:0006606 104 0.012
generation of neurons GO:0048699 152 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
Human
sensory perception of bitter taste GO:0050913 28 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
single organism cellular localization GO:1902580 332 0.012
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
carbohydrate metabolic process GO:0005975 207 0.012
positive regulation of neutrophil apoptotic process GO:0033031 1 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
dna repair GO:0006281 198 0.012
detection of biotic stimulus GO:0009595 21 0.012
tissue morphogenesis GO:0048729 96 0.012
positive regulation of leukocyte activation GO:0002696 80 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
response to lipid GO:0033993 206 0.012
Human
production of molecular mediator of immune response GO:0002440 37 0.012
mononuclear cell proliferation GO:0032943 71 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
regulation of cell motility GO:2000145 299 0.012
viral process GO:0016032 146 0.012
leukocyte mediated cytotoxicity GO:0001909 27 0.012
nuclear export GO:0051168 69 0.012
negative regulation of locomotion GO:0040013 118 0.012
Human
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.012
antigen receptor mediated signaling pathway GO:0050851 38 0.012
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.012
multi organism metabolic process GO:0044033 41 0.012
Human
detection of stimulus involved in sensory perception GO:0050906 43 0.012
regulation of anion transport GO:0044070 25 0.012
regulation of tumor necrosis factor production GO:0032680 43 0.012
Human
negative regulation of proteolysis GO:0045861 132 0.012
Human
response to growth factor GO:0070848 205 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
cell type specific apoptotic process GO:0097285 125 0.011
positive regulation of multi organism process GO:0043902 56 0.011
cellular component disassembly GO:0022411 92 0.011
regulation of binding GO:0051098 111 0.011
lipid metabolic process GO:0006629 381 0.011
positive regulation of response to external stimulus GO:0032103 88 0.011
Human
autophagic cell death GO:0048102 3 0.011
rna interference GO:0016246 4 0.011
protein processing GO:0016485 226 0.011
Human
positive regulation of interleukin 1 beta secretion GO:0050718 11 0.011
blastoderm segmentation GO:0007350 2 0.011
locomotory behavior GO:0007626 1 0.011
neurological system process GO:0050877 163 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
Mouse
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.011
regulation of cellular ketone metabolic process GO:0010565 50 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
membrane hyperpolarization GO:0060081 1 0.011
negative regulation of cytoplasmic transport GO:1903650 46 0.011
cytokinesis GO:0000910 96 0.011
cellular amine metabolic process GO:0044106 41 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.011
Human
nucleoside monophosphate catabolic process GO:0009125 159 0.011
viral gene expression GO:0019080 35 0.011
Human
single organism carbohydrate metabolic process GO:0044723 193 0.011
positive regulation of map kinase activity GO:0043406 80 0.011
growth GO:0040007 202 0.011
toxin transport GO:1901998 4 0.011
response to organic cyclic compound GO:0014070 204 0.011
post embryonic development GO:0009791 2 0.011
positive regulation of viral entry into host cell GO:0046598 3 0.011
regulation of cell activation GO:0050865 125 0.011
regulation of calcium ion transport GO:0051924 79 0.011
Human
response to organonitrogen compound GO:0010243 156 0.011
tissue homeostasis GO:0001894 63 0.011
protein autoprocessing GO:0016540 4 0.011
atp metabolic process GO:0046034 176 0.011
negative regulation of intracellular transport GO:0032387 60 0.011
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.010
nucleotide catabolic process GO:0009166 408 0.010
epithelium migration GO:0090132 119 0.010
regulation of activated t cell proliferation GO:0046006 12 0.010
oogenesis GO:0048477 2 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.010
response to interferon gamma GO:0034341 39 0.010
cellular protein complex assembly GO:0043623 188 0.010
Human
positive regulation of t cell activation GO:0050870 54 0.010
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.010
protein import GO:0017038 130 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
stress activated protein kinase signaling cascade GO:0031098 94 0.010

TRIM38 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.037
nervous system disease DOID:863 431 0.037
central nervous system disease DOID:331 186 0.030
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
auditory system disease DOID:2742 53 0.014
disease of metabolism DOID:0014667 295 0.014
eye and adnexa disease DOID:1492 150 0.012